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成果及论文

完整论文发表情况见:https://orcid.org/0000-0002-3709-072X


Year-2024--------------------------------------------------------------------------------------------------------------------------------------------


32. Qu, H.;  Wu, J.;  Pan, Y.;  Abdulla, A.;  Duan, Z.;  Cheng, W.;  Wang, N.;  Chen, H.;  Wang, C.;  Yang, J.;  Tang, J.;  Yang, C.;  Wu, C.*; Xue, X.*, Biomimetic Nanomodulator Regulates Oxidative and Inflammatory Stresses to Treat Sepsis-Associated Encephalopathy. ACS Nano 2024, 18, 41, 28228–28245 doi: 10.1021/acsnano.4c08157. IF=15.8



31. Chen, H.;  Qu, H. *; Pan, Y.; Cheng, W.; Xue, X*. Manganese-coordinated nanoparticle with high drug-loading capacity and synergistic photo-/immuno-therapy for cancer treatments. Biomaterials, 2025, 312, 122745. IF=12.8


30. Chen, H.;  Qu, H.;  Lu, B.;  Pan, Y.;  Yang, J.;  Duan, Z.;  Wu, J.;  Wang, Y.;  Wang, C.;  Hu, R.*; Xue, X.*, A metal-coordination stabilized small-molecule nanomedicine with high drug-loading capacity and synergistic photochemotherapy for cancer treatment. Nanoscale 2024, 16, 14734-14747. IF=5.8. Selected as "Nanoscale 2024 HOT article" and "Nanoscale 2024 Emerging Investigators (新锐科学家)"


29. Pan, Y. Xue, X*. Liang, X-J*. Nanotechnology-Empowered Combination Cancer Immunotherapies: Mechanisms, Synergies, and Perspectives,  Advanced NanoBiomed Research2024, 0, 2300129 (Invited review). IF=4.0

28. Wang, Y.†; Dong, H.†; Qu, H.; Cheng, W.; Chen, H.; Gu, Y.; Jiang, H.*; Xue, X.*; Hu, R.* Bio-mimetic lung-targeting nanoparticles with antioxidative and Nrf2 activating properties to treat ischemia reperfusion induced acute lung injury, Nano Letters, 2024, 24 (7), 2131-2141  IF=10.8  封面



Year-2023--------------------------------------------------------------------------------------------------------------------------------------------


27. Qu, H.†; Li, L.†; Chen, H.; Tang, M.; Cheng, W.; Lin, T-Y.; Li, L.; Li, B.;* Xue, X.* Drug-drug conjugates self-assembled nanomedicines triggered photo-/immuno- therapy for synergistic cancer treatments. Journal of Controlled Release, 2023, 363, 361-375. IF=10.8

26. Qu, H.†; Chen, H.†; Cheng, W.; Pan, Y.; Duan, Z.; Wang, Y.; Liang, X-J.*; Xue, X.* Charge-Reversible Crosslinked Nanoparticle for Improved Pro-Apoptotic Peptide Delivery and Synergistic Photodynamic Cancer Therapy. Nano Research2023 16 (12): 13267-13282 IF=10.269

25. Xue, X.; Qu, H.†; Bo, R.†; Zhang, D.; Zhu, Z.; Xiang, B.; Li, L.; Ricci, M.; Pan, C-X.; Lin, T-Y.; Li, Y.*; A Transformable Nanoplatform with Multiple Therapeutic and Immunostimulatory Properties for Treatment of Advanced Cancers. Biomaterials 2023, 299, 122145. IF=15.03

24. Li, G.; Song, Z.; Ru, Y.; Zhang, J.; Luo, L.; Yang, W.; Wu, H.; Jin, H.; Bao, X.; Wei, D.; Zhao, Y.; Qu, H.; Zhu, Z.*; Xue, X.*; Zhou, G.*, Small-molecule nanoprodrug with high drug loading and EGFR, PI3K/AKT dual-inhibiting properties for bladder cancer treatment. Exploration  2023,  00, 20220141. IF=N/A

23. Qu, H.; Chen, H.; Cheng, W.; Wang, Y.; Xia, Y.; Zhang, L.; Ma, B.; Hu, R.*; Xue, X.*; A Supramolecular Assembly Strategy for Hydrophilic Drug Delivery towards Synergistic Cancer Treatment. Acta Biomaterialia 2023, 164, 407. IF=10.633

22. Qu, H.; Jin, X.; Cheng, W.; Wu, D.; Ma, B.; Lou, C.; Zheng, J.; Jing, L.*; Xue, X.*; Wang, Y.*, Uncovering the Fate and Risks of Intravenously injected Prussian Blue Nanoparticles in mice by an Integrated Methodology of Toxicology, Pharmacokinetics, Proteomics and Metabolomics. Particle and Fibre Toxicology, 2023, 20, 18. IF=9.112

21. Li, L.; Lindstrom, A.; Birkeland, A.; Tang, M.; Lin, T-Y.; Zhou, Y.*; Xiang, B.*; Xue, X.*; Li, Y.*, Deep tumor-penetrating nano-delivery strategy to improve diagnosis and therapy in patient-derived xenograft (PDX) oral cancer model and patient tissue. Nano Research 2023, 16, 2927–2937. IF=10.269



Year-2022--------------------------------------------------------------------------------------------------------------------------------------------

20. Xue, X.*; Qu, H.; Li, Y.*, Stimuli-Responsive Crosslinked Nanomedicine for Cancer Treatment.Exploration 2022, 20210134. IF=N/A Wiley高贡献作者奖

19. Chen, H.; Timashev, P.; Zhang, Y.; Xue, X.*; Liang, X.-J.*, Nanotechnology-based combinatorial phototherapy for enhanced cancer treatment. RSC Advances 202212 (16), 9725-9737. IF= 4.036

18. Zhang, Y.†; Qu, H.†; Xue, X.*, Blood-brain barrier penetrating liposomes with synergistic chemotherapy for glioblastoma treatment. Biomaterials Science 202210 (2), 423-434. IF=7.59



Before SJTU--------------------------------------------------------------------------------------------------------------------------------------------

17. Xue, X.†; Ricci, M.†; Qu, H.; Lindstrom, A.; Zhang, D.; Wu, H.; Lin, T.-Y.; Li, Y.*, Iron-crosslinked Rososome with robust stability and high drug loading for synergistic cancer therapy.Journal of Controlled Release 2021329, 794-804. IF=11.47

16. Wang, Z.Xue, X.; Lu, H.; He, Y.; Lu, Z.; Chen, Z.; Yuan, Y.; Tang, N.; Dreyer, C. A.; Quigley, L.; Curro, N.; Lam, K. S.; Walton, J. H.; Lin, T.-y.; Louie, A. Y.; Gilbert, D. A.; Liu, K.; Ferrara, K. W.; Li, Y.*, Two-way magnetic resonance tuning and enhanced subtraction imaging for non-invasive and quantitative biological imaging. Nature Nanotechnology 202015, 482–490. IF=39.213. 被中外媒体报道99次,包括F1000,福布斯 (Forbes),科学日报 (ScienceDaily),新浪网,生物艺术,纳米人等知名媒体。F1000 (Rated Exceptional)。

15. Xue, X.; Huang, Y.; Bo, R.; Jia, B.; Wu, H.; Yuan, Y.; Wang, Z.; Ma, Z.; Jing, D.; Xu, X.; Yu, W.; Lin, T.-y.; Li, Y.*, Trojan Horse nanotheranostics with dual transformability and multifunctionality for highly effective cancer treatment. Nature Communications 20189 (1), 3653. IF= 17.7申请PCT国际专利一项。基于该工作的纳米药物已帮助实验室拿到600余万美元的基金资助,包括1个小型企业创新研究基金 (SBIR) 和2个美国国立卫生院的研究项目基金 (R01)。

14. Xue, X.; Zhao, Y.; Dai, L.; Zhang, X.; Hao, X.; Zhang, C.; Huo, S.; Liu, J.; Liu, C.; Kumar, A.; Chen, W.-Q.; Zou, G.; Liang, X.-J.*, Spatiotemporal Drug Release Visualized through a Drug Delivery System with Tunable Aggregation-Induced Emission. Advanced Materials 201426 (5), 712-717. IF= 32.08. 首次用聚集诱导发光分子递送药物的工作之一,被聚集诱导发光概念的提出者唐本忠院士撰文,以“有价值的化学”高亮报道在美国化学学会网站上. 

13. Xue, X.; Bo, R.; Qu, H.; Jia, B.; Xiao, W.; Yuan, Y.; Vapniarsky, N.; Lindstrom, A.; Wu, H.; Zhang, D.; Li, L.; Ricci, M.; Ma, Z.; Zhu, Z.; Lin, T.-y.; Louie, A. Y.; Li, Y.*, A nephrotoxicity-free, iron-based contrast agent for magnetic resonance imaging of tumors. Biomaterials 2020257, 120234. IF=15.03.

12. Xue, X.; Huang, Y.; Wang, X.; Wang, Z.; Carney, R. P.; Li, X.; Yuan, Y.; He, Y.; Lin, T.-y.; Li, Y.*, Self-indicating, fully active pharmaceutical ingredients nanoparticles (FAPIN) for multimodal imaging guided trimodality cancer therapy. Biomaterials 2018161, 203-215. IF=15.03.

11. Xue, X.; Jin, S.; Zhang, C.; Yang, K.; Huo, S.; Chen, F.; Zou, G.; Liang, X.-J.*, Probe-Inspired Nano-Prodrug with Dual-Color Fluorogenic Property Reveals Spatiotemporal Drug Release in Living Cells. ACS Nano 2015, 9(3), 2729-2739. IF= 18.02.

10. Wang, Z.Xue, X.; He, Y.; Lu, Z.; Jia, B.; Wu, H.; Yuan, Y.; Huang, Y.; Wang, H.; Lu, H.; Lam, K. S.; Lin, T.-Y.; Li, Y., Novel Redox-Responsive Polymeric Magnetosomes with Tunable Magnetic Resonance Property for In Vivo Drug Release Visualization and Dual-Modal Cancer Therapy. Advanced Functional Materials 20180 (0), 1802159. IF=19.92.

9. Xue, X.; Jin, S.; Li, Z.; Zhang, C.; Guo, W.; Hu, L.; Wang, P. C.; Zhang, J.; Liang, X.-J.*, Through-Bond Energy Transfer Cassette with Dual-Stokes Shifts for “Double Checked” Cell Imaging. Advanced Science 2017, 1700229. IF=17.52

8. Yuan, Y.; Bo, R.; Jing, D.; Ma, Z.; Wang, Z.; Lin, T.-y.; Dong, L.; Xue, X.*; Li, Y.*, Excipient-free porphyrin/SN-38 based nanotheranostics for drug delivery and cell imaging. Nano Research202013, 503-510. IF=10.26

7. Yu, W.Xue, X.; Ma, A.-H.; Ruan, Y.; Zhang, H.; Cheng, F.; Li, Y.*; Pan, C.-X.*; Lin, T.-Y.*, Self-Assembled Nanoparticle-Mediated Chemophototherapy Reverses the Drug Resistance of Bladder Cancers through Dual AKT/ERK Inhibition. Advanced Therapeutics 2020, 3, 2000032. IF=5.002. 

6. Xue, X.; Lindstrom, A.; Qu, H.; Li, Y.*, Recent advances on small-molecule nanomedicines for cancer treatment. WIREs Nanomedicine and Nanobiotechnology 201912 (3), e1607. IF=10.86

5. Xue, X.; Lindstrom, A.; Li, Y.*, Porphyrin-Based Nanomedicines for Cancer Treatment. Bioconjugate Chemistry 201930 (6), 1585-1603. IF=6.06
4. Yuan, Y.; He, Y.; Bo, R.; Ma, Z.; Wang, Z.; Dong, L.; Lin, T.-y.; Xue, X.*; Li, Y.*, A facile approach to fabricate self-assembled magnetic nanotheranostics for drug delivery and imaging. Nanoscale 201810 (46), 21634-21639. IF=8.3

3. Yang, X.Xue, X.; Luo, Y.; Lin, T.-y.; Zhang, H.; Lac, D.; Xiao, K.; He, Y.; Jia, B.; Lam, K. S.*; Li, Y.*, Sub-100nm, long tumor retention SN-38-loaded photonic micelles for tri-modal cancer therapy. Journal of Controlled Release 2017261, 297 - 306. IF=11.47.

2. Xue, X.; Xu, J.; Wang, P. C.; Liang, X.-J.*, Subcellular behaviour evaluation of nanopharmaceuticals with aggregation-induced emission molecules. Journal of Materials Chemistry C 20164, 2719-2730. IF=8.06.

1. Xue, X. †; Zhao, Y. †; Zhang, X.; Zhang, C.; Kumar, A.; Zhang, X.; Zou, G.; Wang, P.; Zhang, J.; Liang, X.-J.*, Phenylboronic acid-functionalized magnetic nanoparticles for one-step saccharides enrichment and mass spectrometry analysis. Biophysics Report 2015, 1 (2), 61-70. IF=N/A