祝贺课题组和国家纳米科学中心梁兴杰研究员合作的邀稿综述发表在《Adv. NanoBiomed Res.》上,第一作者为课题组直博生潘雨晴.
感谢课题组长导师梁兴杰研究员给予的邀稿机会,以及审稿人和主编的认可。
Title: Nanotechnology-Empowered Combination Cancer Immunotherapies: Mechanisms, Synergies, and Perspectives
Link: https://onlinelibrary.wiley.com/doi/10.1002/anbr.202300129
Abstract:
This review is aiming to systematically elucidate the unique role of nanotechnology in optimizing therapeutic modalities for combinatorial cancer immunotherapy, which enables the synergistic integration of multiple treatment strategies. In particular, nanotechnology has enabled the synergistic combination of immunotherapy with physical therapies, chemotherapy, metal therapy, and nucleic acid therapy. In each combination regimen, nanocarriers play multifaceted roles by achieving targeted codelivery of different therapeutics and optimizing each individual treatment modality. This offers new paradigms to guide precision medicine in cancer treatment. Immunotherapy alone is unlikely to achieve personalized precision medicine for cancer, and new treatment modalities are needed in the future. To overcome technical bottlenecks and realize precise regulation of the tumor microenvironment for personalized cancer treatment, it is crucial to develop novel nanosystems with integrated sensing, targeting, and therapeutic functionalities.