论文

25 Synthesis of Benzo[6,6]-Spiroketal Compounds

DU Xiao（杜笑）, TANG Yuqin, CHEN Weiyu, MA Aijun*

Chinese Journal of Synthetic Chemistry, 2024, 32, 737-742.

24 De novo synthesis of atropisomeric benzofurans via Cu/SPDO complex catalyzed asymmetric formal [3 + 2] annulation

Fan-Xiao Meng（孟凡晓）, Xing-Yu Wang, Ka Lu, Ju-Song Yang, Fu-Min Zhang,* Ai-Jun Ma,* Bao Du, Yong-Qiang Tu*

Sci. China Chem. 2024, 67, https://doi.org/10.1007/s11426-024-2174-x.

23 Copper-Catalyzed Sequential C(sp2)−H/C(sp3)−H Annulation of Indoles with Propargylic Alcohols to Access Hydrobenzo[b]carbazoles

Yi-Rui Zhang, Zong-Wang Qiu, Zhao-Jie Fu, Shao-Shuai Chen, Han-Peng Pan, Bao Qiong Li, Ai-Jun Ma*, Xiang-Zhi Zhang*

Advanced Synthesis & Catalysis, 2024, 336, 1320-1324.

22 Cooperative Cu/Pd-Catalyzed 1,5-Boroacylation of Cyclopropyl-Substituted Alkylidenecyclopropanes

Hui-Hui Zeng, Yu-Qing Wang, Yong-Yu He, Xiao-Ling Zhong, Hongguang Li, Ai-Jun Ma*, and Jin-Bao Peng*

J. Org. Chem. 2024,  89, 2637–2648.

21 Acid-Promoted Cyclization of α-Azidobenzyl Ketones through C═N Bond Formation: Synthesis of 6-Substituted Quinoline Derivatives

Jing-Yun Zheng（郑景云）, Ying Luo, Ting-Ting Ou, Xin-Jie Zhang, Yong-Qiang Lao, Na Feng, Jin-Bao Peng, Xiang-Zhi Zhang, Xiaojun Yao, and Ai-Jun Ma*


Org. Lett. 2024, 26, 586-590.










20  Ruthenium-Catalyzed Carbonylation of α-Aminoaryl-Tethered Alkylidenecyclopropanes: Synthesis of Eight-Membered Benzolactams  

Miao-Miao Ji, Peng-Rui Liu, Jun-Dong Yan, Yong-Yu He, Hongguang Li, Ai-Jun Ma*, and Jin-Bao Peng*

Org. Lett. 2024, 26, 231-235.






19 Direct syntheses of N-alkyl-2-pyridones using 2-halogenated pyridines

Xia Chen（陈霞）, Jianyi Shi, Yuqun Lin, Yibiao Li, Shaohua Jiang, Tianxiang Chen, Zhongzhi Zhu*, Ai-Jun Ma*

Eur. J. Org. Chem. 2023, e202301184.






18 Synthesis of Benzo[6,6]-Spiroketal Compounds

LIN Siwu（林思武）, ZHAO Lili, SHEN Zhonghui, MA Ai-Jun*

Chinese Journal of Synthetic Chemistry, 2023, 31, 252-256.




17 Total Synthesis of (+)-Peniciketal B

 Shan-Shan Li（李汕珊）, Li-Li Zhao（赵丽丽）, Min Pan, Na Feng, Bao-Qiong Li, Xiang-Zhi Zhang, Jin-Bao Peng*, and Ai-Jun Ma*

Org. Lett. 2023, 25, 8501–8505.






16 Palladium-Catalyzed Intramolecular Heck/Aminocarbonylation of Alkene-Tethered Iodobenzenes with Nitro Compounds: Synthesis of Carbamoyl-Substituted Benzoheterocycles

Yun Kang, Jin-Liang Lu, Zhi Zhang, Ying-Kang Liang, Ai-Jun Ma*, and Jin-Bao Peng*

J. Org. Chem. 2023, 88, 5097–5107.







15 Ring-Opening-Recombination Strategy Based on 2-Methylbenzothiazole Salts: Syntheses of Thiazinopyrrole Fused-Ring Derivatives

Shengting Xu, Zhongzhi Zhu, Zhendong Yang, Zuyu Mai, Tianxiang Chen, Ai-Jun Ma*,  Xiuwen Chen* 

Advanced Synthesis & Catalysis, 2023, 365, 3819-3823.










14 K2CO3-Promoted oxy-Michael Addition/Cyclization of α,β-Unsaturated Carbonyl Compounds with Naphthols: Synthesis of Naphthopyrans

 Shan-Shan Li（李汕珊）, Li-Li Zhao（赵丽丽）, Min Pan, Na Feng, Jin-Bao Peng, and Ai-Jun Ma^*

Molecules, 2023, 28, 5502.









13 Synthesis and Antioxidant Activities of Novel Melatonin Derivatives

HE Li（贺利）, CHEN Mengting, ZHOU Junjie, LUO Lu, FENG Na^*, MA Ai-Jun^*

^{Chinese Journal of Synthetic Chemistry, 2022, 30, 893-901.}




12 Total synthesis of bi-magnolignan

Si-Yuan Lu（卢思远）, Hong-Mei Wang, Na Feng* and Ai-Jun Ma*

RSC Adv., 2023, 13, 8844-8846. 









11 Studies toward synthesis of the core skeleton of spiroaspertrione A

Zhong-Hui Shen（沈中辉）, Si-Yuan Lu, Jing-Yun Zheng, Xiang-Zhi Zhang, Jin-Bao Peng, Ai-Jun Ma*

Frontiers in Chemistry, 2022, doi:10.3389/fchem.2022.1022533






10 Synthesis of melatonin derivatives and the neuroprotective effects in Parkinson's disease models of Caenorhabditis elegans

Li He（贺利）, Jing-Jing Du, Meng-Ting Chen, Jun-Jie Zhou, Lu Luo, Baoqiong Li, Xiang-Zhi Zhang, Wen-Zhe Ma, Ai-Jun Ma*, Na Feng*

Frontiers in Chemistry, 2022, doi:10.3389/fchem.2022.918116/abstract







9 Intramolecular Aerobic Ring Expansion of Cyclic Ketone: A Mild Method for the Synthesis of Medium-Sized Lactones and Macrolactones

Qi-Ming Liang（梁绮明）,Jing-Yun Zheng, Si-Yuan Lu, Hong-Mei Wang, Lu Luo, Xiang-Zhi Zhang, Jin-Bao Peng, Na Feng, Ai-Jun Ma*

Advanced Synthesis & Catalysis, 2022, 364, 2152-2156.  (Featured in Org. Chem. Highlights)






8 Synthesis of disubstituted γ-butyrolactones and spirocyclopropanes via a multicomponent reaction of aldehydes, Meldrum’s acid and sulfoxonium ylides

Shan-Shan Li（李汕珊）, Qi Qin, Zhuang Qi, Li-Miao Yang, Yun Kang, Xiang-Zhi Zhang, Ai-Jun Ma* and Jin-Bao Peng *

Org. Chem. Front., 2021, 8, 3069-3075.



 

7 Synthesis of Cinnamic Acid Ester Derivatives of Chrysin

CHEN Han-qia（陈汉洽）, YANG Meng-yuan, WEI Dong-mei, HE Li, ZHENG Jing-yun, LI Jie-fang, ZHONG Hao-liang, FENG Na, MA Ai-jun*, ZHANG Shu-yu*, ZHANG Kun*,

Chin. J. Syn. Chem. 2020, 28, 848-854.

 

6 Recent Progress in Synthesis of Polysubstituted Pyrazoles

Wang, Shaohua, Zhang, Banghong, Chen, Jie, Zheng, Yingying, Feng, Na, Ma, Aijun*, Xu, Xuetao*, Abdullah, M. Asirid

Chin. J. Org. Chem. 2020, 40, 15-27.



 

5 Synthesis and biological evaluation of coumarin derivatives as aglucosidase inhibitors

Xue-Tao Xu, Xu-Yang Deng, Jie Chen, Qi-Ming Liang, Kun Zhang, Dong-Li Li, Pan-Pan Wu, Xi Zheng, Ren-Ping Zhou, Zheng-Yun Jiang, Ai-Jun Ma*, Wen-Hua Chen*, Shao-Hua Wang*

Eur. J. Med. Chem. 2020, 189, 112013.



 

4 Synthetic Studies on the Kigamicins

Ai-Jun Ma and Joseph M. Ready*

Org. Lett. 2019, 21, 1148−1151.



 

Before 2018

3 Synthesis and Biological Evaluation of Kibdelone C and Its Simplified Derivatives

Janjira Rujirawanich, Soyeon Kim, Ai-Jun Ma, John R. Butler, Yizhong Wang, Chao Wang, Michael Rosen, Bruce Posner, Deepak Nijhawanc, and Joseph M. Ready*,

J. Am. Chem. Soc. 2016, 138, 10561-10570.



 

2 Total Synthesis of the Nominal Didemnaketal A

Fu-Min Zhang, Lei Peng, Hui Li, Ai-Jun Ma, Jin-Bao Peng, Jing-Jing Guo, Dengtao Yang, Si-Hua Hou, Yong-Qiang Tu^*, and William Kitching

Angew. Chem. Int. Ed. 2012, 51, 10846-10850.



 

1 Total Synthesis of (-)-FR901483

Ai-Jun Ma, Yong-Qiang Tu^*, Jin-Bao Peng, Qing-Yun Dou, Si-Hua Hou, Fu-Min Zhang, and Shao-Hua Wang

Org. Lett. 2012, 14, 3604–3607.






专利

7 马爱军；王红梅；梁绮明；冯娜 “一种羧酸类化合物及其制备方法与应用”，2024.09.24（授权），中国，ZL202310103680.9

6 陈霞；马爱军；师建毅；陈修文；朱忠智 “一种金鸡纳碱衍生物及其制备方法和应用”，2024.03.26（授权），中国，ZL202211233912.4

5 马爱军；李汕珊；赵丽丽；潘敏；冯娜；陈春灵；游松涛 “一种苯并吡喃类化合物及其制备方法”，2024.01.12（授权），中国，ZL202210881947.2 

4 马爱军；贺利；朱瑞焘；周俊杰；陈梦婷；文慧心；罗路；冯娜 “一种褪黑激素肉桂酸衍生物及其制备方法”，2023.07.04（授权），中国，ZL202210518275.9 

3 冯娜；贺利；杨梦圆；韦冬梅；马爱军 “一种白杨素肉桂酸酯或其衍生物及其制备方法”，2023.02.17（授权），中国，ZL 202010891873.1

2 马爱军；梁绮明；欧婷婷；郑景云；李凤萍；卢思远；冯娜；陈春灵；游松涛 “2-乙基-3,4-二氢-1(2H)-异喹啉酮的制备方法”，2022.6.21（授权），中国，ZL202110688971.X

1 涂永强; 马爱军 “一种免疫抑制剂FR901483中间体及其合成方法”2015.2.18（授权），中国，CN102643276B







教学

中国大学慕课《药物化学》

《药物化学》是一门发现与发明新药、合成化学药物、阐明药物化学性质、研究药物分子与机体细胞（生物大分子）之间相互作用规律的综合性学科，是药学领域中重要的带头学科。本课程由大湾区九所高校十名老师共同倾力打造！采九校之石可以攻玉，纳十师之长可以厚己。一起学习《药物化学》，走近新药梦开始的地方。 —— 课程团队