1. 基于光敏显色的核酸检测：

我们着眼于开发能在水溶液中诱导室温磷光的新型基质，并将室温磷光信号转换成更容易测定的显色或化学发光信号，并在此基础上实现高灵敏检测。

代表性论文：

1. Wang, Y. Y.; Hu, H.; Dong, T. Y.; Mansour, H.; Zhang, X. F.; Li, F.*; Wu, P.* Double Stranded DNA Matrix for Photosensitization Switching. CCS Chem. 2020, 2, 2394-2404.

2. Dong, T. Y.; Mansour, H.; Hu, H.; Wang, G. A.; Watson, C. J. F.; Yousef, M.; Matamoros, G.; Sanchez, A. L.; MacNeil, A. J.; Wu, P.*; Li, F.* Colorimetric Polymerase Chain Reaction Enabled by a Fast Light-Activated Substrate Chromogenic Detection Platform. Anal. Chem. 2020, 92, 6456-6461.
   

3. Li, X. M.; Zheng, T.; Xie, Y.-N.; Li, F.*; Jiang, X.; Hou, X. D.; Wu, P.* Recombinase Polymerase Amplification Coupled with Photosensitization Colorimetric Assay for Fast Salmonella spp. Testing. Anal. Chem. 2021, 93, 6559-6566.
   

4. Hu, H.; Zhang, J.; Ding, Y.; Zhang, X.; Xu, K. L.*; Hou, X.; Wu, P* Modulation of the Singlet Oxygen Generation from the Double Strand DNA-SYBR Green I Complex Mediated by T-Melamine-T Mismatch for Visual Detection of Melamine. Anal. Chem. 2017, 89, 5101-5106.
   

5. Zhang, X. F.; Huang, C. P.; Xu, S. X.; Chen, J. B.; Zeng, Y.; Wu, P*; Hou, X. D.* Photocatalytic Oxidation of TMB with the Double Strand DNA-SYBR Green I Complex for Label-Free and Universal Colorimetric Bioassay. Chem. Commun., 2015, 51, 14465-14468. 
   

2. 新型光敏剂的开发：

基于光敏剂的工作原理，着眼于其光物理和光化学过程的调控，开发新型光敏剂，用于可视化分析和光动力抗菌等。

代表性论文：

1. Wang, Y.; Li, J. Z.; Zhou, Z. W.; Zhou, R. H.; Sun, Q.; Wu, P.* Halo-Fluorescein for Photodynamic Bacteria Inactivation in Extremely Acidic Conditions. Nat. Commun. 2021, 12, 526.

2. Zhang, J. Y.; Wu, S. H.; Lu, X. M.; Wu, P.*; Liu, J. W.* Manganese as a Catalytic Mediator for Photo-oxidation and Breaking the pH Limitation of Nanozymes. Nano Lett. 2019, 19, 3214-3220. 

3. Li, C. B.; Wang, Y.; Li, C. H.; Xu, S. X.*; Hou, X. D.; Wu, P* Simultaneously Broadened Visible Light Absorption and Boosted Intersystem Crossing in Platinum-Doped Graphite Carbon Nitride for Enhanced Photosensitization. ACS Appl. Mater. Interfaces 2019, 11, 20770-20777.

4. Zhang, J. Y.; Wu, S. H.; Lu, X. M.; Wu, P.*; Liu, J. W.* Lanthanide Boosted Singlet Oxygen from Diverse Photosensitizers along with Potent Photocatalytic Oxidation. ACS Nano 2019, 13, 14152-14161.

5. Zhang, J. Y.; Lu, X. M.; Tang, D. D.; Wu, S. H.; Hou, X. D.; Liu, J. W.*; Wu, P* Phosphorescent Carbon Dots for Highly Efficient Oxygen Photosensitization and as Photooxidative Nanozymes. ACS Appl. Mater. Interfaces, 2018, 10, 40808-40814.

3. 新型磷光材料及其在分析检测中的应用：

开发新型磷光材料，探究其在分析化学和环境化学中的应用。

代表性论文：

1. Zheng, H. Y.; Cao, P. S.; Wang, Y. Y.; Lu, X. M.; Wu, P.* Ultralong Room-Temperature Phosphorescence from Boric Acid. Angew. Chem. Int. Ed. 2021, 60, 9500-9506.

2. Zheng, H. Y.; Wang, Y. Y.; Cao, P. S.; Wu, P.* Color-Tunable Ultralong Room Temperature Phosphorescence from EDTA. Chem. Commun. 2021, 57, 3575-3578.

3. Lu, X. M.; Zhang, J. Y.; Xie, Y.-N.; Zhang, X. F.; Jiang, X. M.*; Hou, X. D.; Wu, P*  Ratiometric Phosphorescent Probe for Thallium in Serum, Water, and Soil Samples Based on Long-Lived, Spectrally-Resolved Mn-doped ZnSe Quantum Dots and Carbon Dots, Anal. Chem., 2018, 90, 2939-2945.

4. Zhou, R. H.; Sun, S.-K.; Li, C. H.; Wu, L.; Hou, X. D.*; Wu, P* Enriching Mn-Doped ZnSe Quantum Dots onto Mesoporous Silica Nanoparticles for Enhanced Fluorescence/Magnetic Resonance Imaging Dual-Modal Bio-Imaging, ACS Appl. Mater. Interfaces, 2018, 10, 34060-34067.

5. He, H. W.; Li, C. H.; Tian Y. F.*; Wu, P*; Hou, X. D. Phosphorescent Differential Sensing of Physiological Phosphates with Lanthanide Ions-Modified Mn-Doped ZnCdS Quantum Dots, Anal. Chem., 2016, 88, 5892-5897.