四川大学华西医院助理研究员
近年来的研究工作主要以光敏显色和核酸扩增为技术基础，构建新型比色传感方法和现场分子诊断技术。
E-mail: lixianming@scu.edu.cn
在研项目：
国家自然科学基金青年基金：基于P2O74-调控的实时比色PCR体系构建及其在致病菌精准筛查中的应用（批准号：22204109；起讫年月：2023.1-2025.12），经费：30万
中国博士后面上基金：基于焦磷酸根调控的PCR比色试纸及其在致病菌精准筛查中的应用探究（批准号：2022M722263；起讫年月：2023.1-2025.12），经费：8万
四川省科技厅自然科学基金：基于光敏显色纸基的核酸现场检测方法研究（批准号：2022NSFSC1222；起讫年月：2023-2024），经费：10万
博士毕业后论文：
Li, X. M.†; Tang, H. H.†; Chen, C. Y.; Niu, Q.; Zhou, Z.; Zheng, Y. T.; Liu, Y.; Muñoz, L. E.; Herrmann, M.; Wu, P.; Zhao, Y. Improved Diagnosis of Systemic Lupus Erythematosus with Human-Derived Double-Stranded DNA Antigen, Biosens. Bioelectron. 2025, 267, 116809. (†: equal contribution)
Li, X. M.; Li, L.; Tang, H. H.; Xie, C. X.; Zhao, Y.*; Wu, P.* Non-Colorimetric Sensing with 3,3´,5,5´-Tetramethylbenzidine. Sens. Actuators B, 2025, 422, 136643.
Li, L.†; Li, X. M.†; Liu, X. H.; Jiang, X. M.*; Wu, P.* A Derivative of 3,3',5,5'-tetramethylbenzidine for Highly Robust Colorimetric Sensing of Nitrite in Food Samples. Sens. Actuators B, 2025, 422, 136671. (†: equal contribution)
Li, X. M.; Zheng, T.; Xiao, Y. L.; Zhao, Y.; Wu, P.* Field-Deployable Colorimetric Array for On-Site Diagnosis of Urinary Tract Infection and Identification of Causative Pathogens, Anal. Chem. 2024, 96, 14679-14687.
Liu, H. L.; Zhang, X.; Li, X. M.*; Wu, P.* NIR-II-Absorbing TMB Derivative for 1064 nm-Excited Photothermal Immunoassay, Anal. Chem. 2024, 96, 5633-5639.
Wang, Y. Y.; Zheng, T.; Li, X. M.*; Wu, P.* Integrating Recombinase Polymerase Amplification and Photosensitization Colorimetric Detection in One Tube for Fast Screening of C. sakazakii in Formula Milk Powder, Anal. Chem. 2024, 96, 5727-5733.
Li, X. M.†; Fan, W. T.†; Tang, H. H.; Li, D. D.; Xiao, Y. L.*; Yang, B.; Zhao, Y.; Wu, P.* Neutral pH photoenzymatic activity of Au-doped g-C3N4 nanosheet for colorimetric detection of total antioxidant capacity in food samples, Food Chem. 2024, 439, 138158. (†: equal contribution)
Xie, C. X.†; Li, X. M.†; Yu, Q. W.; Wang, M. J.; Yang, B.; Ying, B. W.*; Wu, P.* Dual-FRET Aptasensor for Rapid Screening of Ochratoxin A in Food Samples. Sens. Actuators B, 2024, 408, 135515. (†: equal contribution)
Lei, F. J.†; Li, X. M.†; Liu, Y.; Yang B.*; Ying, B. W.; Wu, P.* Visual Monitoring of Lead Exposure in Children’s Daily Activities with an AuNP-based Indicator. Sens. Actuators B 2024, 398, 134731. (†: equal contribution)
Li, X. M.; Li, C. H.; Liu, Y.; Tang, H. H.; Zhao, Y.*; Wu, P.* A portable aptasensor for facile personalized monitoring of serum uric acid, Sens. Actuators B 2023, 394, 134351.
Li, X. M.; Wang, Y. Y.; Tang, H. H.; Yang, B.; Zhao, Y.*; Wu, P.* Evaluation of the Sequence-Dependent Relative Activity of APE1 for Optimal Biosensing Design, Biosens. Bioelectron. 2022, 214, 114539
Li, X. M.†; Yang H.†; He, J. L.; Yang, B.*; Zhao, Y.; Wu, P.* Full Liberation of 2-Aminopurine with Nucleases Digestion for Highly Sensitive Biosensing, Biosens. Bioelectron. 2022, 196, 113721. (†: equal contribution)
博士毕业前论文：
Li, X. M.; Zheng, T.; Xie, Y.-N.; Li, F.*; Jiang, X.; Hou, X. D.; Wu, P.* Recombinase Polymerase Amplification Coupled with Photosensitization Colorimetric Assay for Fast Salmonella spp. Testing, Anal. Chem. 2021, 93, 6559-6566.
Li, X. M.; Gao, L.; Li, F.; Hou, X. D.; Wu, P* Universal and Label-Free Photosensitization Colorimetric Assays Enabled by Target-Induced Termini Transformation of dsDNA Resistant to Exo III Digestion, Chem. Commun. 2019, 55, 7211-7214.
Li, X. M.; Zhang, H. C.; Tang, Y. R.; Wu, P.; Xu, S. X.*; Zhang, X. F.* A Both-End Blocked Peroxidase-Mimicking DNAzyme for Low-Background Chemiluminescent Sensing of miRNA. ACS Sens., 2017, 2, 810-816.
Xu, S. X.; Li, X. M.; Li, C. B.; Li, J. L.; Zhang, X. F.*; Wu, P.*; Hou, X. D. In Situ Generation and Consumption of H2O2 by Bienzyme-Quantum Dots Bioconjugates for Improved Chemiluminescence Resonance Energy Transfer. Anal. Chem., 2016, 88, 6418-6424.（导师第一作者）
Li, X. M.; Zheng, T.; Gao, L.; Li, F.*; Hou, X. D.; Wu, P.* Recombinase Polymerase Amplification: from Principle to Performance. Chem. J. Chin. Univ.-Chin., 2020, 41, 2587-2597.
Ding, Y.†; Li, X. M.†; Zhang, X. F.; Li, F.*; Hou, X. D.; Wu, P.* Systematic Probing the Sequence Selectivity of Exonuclease III with a Photosensitization Colorimetric Assay. ACS Omega, 2019, 4, 13382-13387. (†: equal contribution)
Ye, P. Q.; Li, X. M.; Xie, Y.-N.; Wu, P.* Facile Monitoring of Meat Freshness with a Self-Constructed Photosensitization Colorimetric Instrument, Food Chem. 2022, 385, 132676.
Li, X.; Li, X. M.; Chen, Q.; Chen, J. B.*; Wu, P.* Activating the Neutral pH Photozymatic Activity of g-C3N4 Nanosheet through Post-Synthetic Incorporation of Pt, Chem. Commun. 2022, 58, 6930-6933.