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成果及论文

2019

  • Xu, W., Jiang, H., Leng, J., Ong, H. and Wu, J. (2019), Visible‐Light‐Induced Selective Defluoroborylation of Polyfluoroarenes, gem‐Difluoroalkenes, and Trifluoromethylalkenes. Angew. Chem. Int. Ed.. Accepted Author Manuscript. DOI: 10.1002/anie.201911819
  •  Zhang, Y., Yang, X., Tang, H., Liang, D., Wu, J.*, and Huang, D.* (2019), Pyrenediones as Versatile Photocatalysts for Oxygenation Reactions with in situ Generation of Hydrogen Peroxide under Visible Light.2019, Green Chem., 2019, Accepted Manuscript. DOI: 10.1039/C9GC03152A
  • Kuang, Y. , Wang, K. , Shi, X. , Huang, X. , Meggers, E. and Wu, J.* (2019), Asymmetric Synthesis of 1,4‐Dicarbonyl Compounds from Aldehydes via the Marriage of Hydrogen Atom Transfer Photocatalysis with Chiral Lewis Acid Catalysis. Angew. Chem. Int. Ed.. 2019, 58, 16859-16863. DOI:10.1002/anie.201910414
  • Liu, R., Chia, S. P. M., Goh, Y. Y., Cheo, H. W., Fan, B., Li, R., Zhou, R., Wu, J.* "Visible‐Light‐Mediated Regioselective Allylation, Benzylation, and Silylation of Methylene‐Malononitriles via Photoredox‐Induced Radical Cation Fragmentation" Eur. J. Org. Chem. 2019, Accepted Article. DOI: 10.1002/ejoc.201900902.
  •  Fan, X., Xiao, P., Jiao, Z., Yang, T., Dai, X., Xu, W., Tan, J. D., Cui, G.,* Su, H., Fang, W., Wu, J.* "Neutral-Eosin-Y-Photocatalyzed Silane Chlorination Using Dichloromethane" Angew. Chem. Int. Ed. 2019, 58, 12580-12584. DOI: 10.1002/anie.201908556.
  • Zhou, R., Li, J., Cheo, H. W., Chua, R., Zhan, G., Hou, Z., Wu, J.* "Visible-light-mediated Deuteration of Silanes with Deuterium Oxide" Chem. Sci. 2019, 10, 7340–7344. DOI: 10.1039/C9SC02818H.
  • Xu, J.-H., Wu, W.-B., Wu, J.* "Photoinduced Divergent Alkylation/Acylation of Pyridine N-Oxides with Alkynes under Anaerobic and Aerobic Conditions" Org. Lett. 2019, 21, 5321–5325. DOI: 10.1021/acs.orglett.9b01940.
  • Ou, W., Zhang, G., Wu, J., Su, C.* "Photocatalytic Cascade Radical Cyclization Approach to Bioactive Indoline-Alkaloids over Donor–Acceptor Type Conjugated Microporous Polymer" ACS Catal. 2019, 9, 5178–5183. DOI: 10.1021/acscatal.9b00693.
  • Wong, Y. -C., Wu, W.-B., Wang, T., Ng, J. D. A., Khoo, K. H.,* Wu, J.*, Tan, Z.-K. "Color Patterning of Luminescent Perovskites via Light‐Mediated Halide Exchange with Haloalkanes" Adv. Mater. 2019, 1901247. DOI: 10.1002/adma.201901247.
  • "Young Career Focus: Dr. Jie Wu" Synform 2019, 05, A68–A70. DOI: 10.1055/s-0037-1612161.
  • Ng, C. K., Toh, R. W., Lin, T. T., Luo, H.-K., Hor, T. S. A.,* Wu, J.* "Metal-salen molecular cages as efficient and recyclable heterogeneous catalysts for cycloaddition of CO2 with epoxides at ambient conditions" Chem. Sci. 2019, 10, 1549–1554. DOI: 10.1039/C8SC05019H.
  • Li, J., Luo Y., Cheo, H. W., Lan, Y.,* Wu, J.* "Photoredox Catalysis Modulated Nickel-Catalyzed Divergent Difunctionalization of Ethylene" Chem 2019, 5, 192–203. DOI: 10.1016/j.chempr.2018.10.006.


2018

  • Xue, C.-W., Li, J., Lee, J. P., Zhang, P.,* Wu, J.* "Continuous Amination of Aryl/Heteroaryl Halides Using Aqueous Ammonia in a Teflon AF-2400 Tube-in-Tube Micro-Flow Reactor" Reaction Chemistry & Engineering 2018, 4, 346–350  (Invited article for special issue "RCE Emerging Investigators 2019"). DOI: 10.1039/C8RE00216A.
  • Cao, H., Jiang, H., Feng, H., Kwan, J. M. C., Liu, X., Wu, J.* "Photo-Induced Decarboxylative Heck-Type Coupling of Unactivated Aliphatic Acids and Terminal Alkenes in the Absence of Sacrificial Hydrogen Acceptors" J. Am. Chem. Soc. 2018, 47, 16360–16367. DOI: 10.1021/jacs.8b11218.
  • Hou, J., Ee, A., Cao, H., Ong, H.-W., Xu, J.-H. Wu, J.* "Visible‐Light‐Mediated Metal‐Free Difunctionalization of Alkenes with CO2 and Silanes or C(sp3)-H Alkanes" Angew. Chem. Int. Ed. 2018, 57, 17220–17224. DOI: 10.1002/anie.201811266.
  • Deng, H.-P., Zhou, Q., Wu, J.* "Micro-Tubing Reactor-Assisted Aliphatic C-H Functionalization Utilizing HCl as the Hydrogen Atom Transfer Catalyst Precursor in Conjunction with an Organo Photoredox Catalyst" Angew. Chem. Int. Ed. 2018, 57,12661–12665. DOI: 10.1002/anie.201804844.
  • Wu, W.-B., Wong, Y.-C., Tan, Z.-K.,* Wu, J.* "Photo-induced thiol coupling and C–H activation using nanocrystalline lead-halide perovskite catalysts" Catal. Sci. Technol. 2018, 8, 4257–4263. DOI: 10.1039/c8cy01240g.
  • Li, J.-S., Wu, J.* "Recent Development of Photo-Mediated Generation of Silyl Radicals and Their Application in Organic Synthesis" ChemPhotoChem 2018, 2, 839–846. DOI: 10.1002/cptc.201800110 (Invited Review).
  • Liu, H., Ma, L., Zhou, R., Chen, X.,* Fang, W., Wu, J.* "One-Pot Photo-Mediated Giese Reaction/Friedel-Crafts Hydroxyalkylation/Oxidative Aromatization to Access Naphthalene Derivatives from Toluenes and Enones" ACS Catal. 2018, 8, 6224–6229. DOI: 10.1021/acscatal.8b00481.
  • Hou, J., Li, J.-S., Wu, J.* "Recent Development of Light-Mediated Carboxylation Using CO2 as the Feedstock" Asian J. Org. Chem. 2018, 7, 1439–1447. DOI: 10.1002/ajoc.201800226 (Invited Review).
  • Fan, X.-Z., Rong, J.-W., Wu, H.-L., Zhou, Q., Deng, H.-P., Tan, J. D., Xue, C.-W., Wu, L.-Z., Tao, H.-R., Wu, J.* "Eosin Y as a Direct Hydrogen Atom Transfer Photocatalyst for the Functionalization of C-H Bonds" Angew. Chem. Int. Ed. 2018, 57, 8514–8518. Manuscript. DOI: 10.1002/anie.201803220.
  • Hou, J., Ee, A., Feng, W., Xu, J.-H., Zhao, Y.,* Wu, J.* "Visible-Light-Driven Alkyne Hydro-/Carbocarboxylation Using CO2 via Iridium/Cobalt Dual Catalysis for Divergent Heterocycle Synthesis" J. Am. Chem. Soc. 2018, 140, 5257–5263. DOI: 10.1021/jacs.8b01561.
  • Toh, R. W., Li, J. S., Wu, J. Utilization of Stop-flow Micro-tubing Reactors for the Development of Organic Transformations. J. Vis. Exp. 2018, (131), e56897, doi:10.3791/56897.

 

 2017

  • Zhou, R.; Goh, Y. Y.; Liu, H.; Tao, H.; Li, L.; Wu, J.* “Visible-Light-Mediated Metal-Free Hydrosilylation of Alkenes through Selective Hydrogen Atom Transfer for Si-H Activation” Angew. Chem. Int. Ed. 2017, 56(52), 16621–16625. DOI: 10.1002/anie.201711250.

  • Deng, H.; Fan, X.; Chen, Z.; Xu, Q.; & Wu, J.* "Photo-induced nickel-catalyzed chemo- and regioselective hydroalkylation of internal alkynes with ether and amide a-hetero C(sp3)-H bonds" J. Am. Chem. Soc. 2017, 139, 13579–13584. DOI: 10.1021/jacs.7b08158.

  • Zhou, R.; Liu, H.; Tao, H.; Yu, X.; & Wu, J.* "Metal-free direct alkylation of unfunctionalized allylic/benzylic sp 3 C–H bonds via photoredox induced radical cation deprotonation." Chem. Sci. 2017, 8(6), 4654–4659., DOI: 10.1039/C7SC00953D.

  • Xue, F.†; Deng, H.†; Xue, C.; Mohamed, D. K. B.; Tang, K. Y.; Wu, J.* “Reaction Discovery Using Acetylene Gas as the Chemical Feedstock Accelerated by the ‘Stop-Flow’ Micro-Tubing Reactor System” Chem. Sci. 2017, 8(5), 3623–3627. DOI: 10.1039/C7SC00408G. (†Co-first authors)

  • Wu, J.; Li, J.; Xue, C.; Mohamed D. “Lotus-Type Reactor for Large-Scale Continuous-Flow and Stop-Flow Synthesis” 2017, Patent application No. 10201700300X.


  2016
  • Wu, J.; Deng H.; Xue, F.; Mohamed, D. “Modular ‘Stop-Flow’ Parallel Microtubing Reactor Platform Useful for High-Pressure Reaction Screening” 2016, US 62/320726 (US Provisional Patent).

  • Cai, B., Evans, R. W., Wu, J., & Panek, J. S. Total Synthesis of Nuclear Factor of Activated T-Cells-68 (NFAT-68): Sequential Use of Chiral Allenylsilane and Titanium Alkoxide-Mediated Reductive Coupling Bond Construction. Org. Lett, 2016, 18(17), 4304–4307.

  • Ng, C. K.; Wu, J.*; Hor, T. S. A.*; Luo, H.-K.* “A Binary Catalyst System of a Cationic Ru-CNC Pincer Complex with an Alkali Metal Salt for Selective Hydroboration of Carbon Dioxide” Chem. Comm. 2016, 52, 11842-11845.

  • Mohamed, D. K. B.; Yu, X.-J.; Li, J.-S.; Wu, J.* "Reaction Screening in Continuous Flow Reactors" Tetrahedron Lett. 2016, 57, 3965–3977. (Invited Review)