2099
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成果及论文
  1. Peng Zhang, Guangwei Wu (共一), Stephanie C. Heard, Changshan Niu, Stephen A. Bell, Fengli Li, Ying Ye, Yonghui Zhang, and Jaclyn M. Winter*. Identification and Characterization of a Cryptic Bifunctional Type I Diterpene Synthase Involved in Talaronoid Biosynthesis from a Marine-Derived Fungus Org. Lett. 2022,2438, 7037-7041  https://pubs.acs.org/doi/10.1021/acs.orglett.2c02904  

     

  2. Zhenzhen Zhang, Xueqian He, Xiaomin Zhang, Dehai Li, Guangwei Wu, Zhenzhen Liu, Chao Niu, Lanping Yang, Wenting Song, Zhanlin Li, and Zhenhui Wang* Production of Multiple Talaroenamines from Penicillium malacosphaerulum via One-Pot/Two-Stage Precursor-Directed Biosynthesis. J. Nat. Prod. 2022, 85, 9, 2168–2176 https://doi.org/10.1021/acs.jnatprod.2c00394  

  3. Guangwei Wu*, Xuan Qian, Yeqiang Huang, Yujia Liu, Luning Zhou, Wei Wang, Jing Li, Tianjiao Zhu, Qianqun Gu, and Dehai Li* Nonenzymatic Self-Assembly Access to Diverse ortho-Quinone Methide-Based Pseudonatural Products Org. Lett. 2022, 24, 28, 5235–5239. https://pubs.acs.org/doi/10.1021/acs.orglett.2c02268



  4. Jinteng Cao† , Guangwei Wu†共一), Lei Wang, Fuliang Cao, Yan Jiang,* and  Linguo Zhao,* Oriented Deep Eutectic Solvents as Efficient Approach  for Extraction of Bioactive Saponins from Husks of Xanthoceras sorbifolia  Bunge. Antioxidants 2022, 11(4), 736 https://doi.org/10.3390/antiox11040736


  5. Lu Yang, Guangwei Wu, Fanyue Meng, Huomiao Ran, Wen-Bing Yin,Wei Li*, Xiaoqing Liu* Combination Strategy of Genetic Dereplication and Manipulation of Epigenetic Regulators Reveals a Novel Compound from Plant Endophytic Fungus. Int J Mol Sci. 2022 Mar 28;23(7):3686. doi: 10.3390/ijms23073686




  6. Ting Yang, Jie Liu, Li-Bin Lin, Jia-Yao Hu, Guang-Wei Wu, Pei-Hong Fan, Dong-Zhu Duan, Jian Xiao,*, Xiao-Ling Wang Acrocalysterols A and B, two new steroids from endophytic fungus Acrocalymma sp Phytochemistry Letters 48 (2022) 77–80. https://doi.org/10.1016/j.phytol.2022.02.003


  7. Zhang Jinyu, Zhang Peng, Zeng Guohong, Wu Guangwei, Qi Landa, Chen Guocan, Fang Weiguo, Yin Wen-Bing.Transcriptional Differences Guided Discovery and Genetic Identification of Coprogen and Dimerumic Acid Siderophores in Metarhizium robertsii. Frontiers in Microbiology, 2021,12,783609.                      doi: 10.3389/fmicb.2021.783609.      





  8. Stephanie C Heard, Guangwei Wu*, Jaclyn M Winter*. Antifungal Natural Products Curr. Opin. Biotechnol. 2021, 69, 232–241. https://doi.org/10.1016/j.copbio.2021.02.001




  9. Guangwei Wu, Bryn T. M. Dentinger, Jason R. Nielson, Rand.all T. Peterson, Jaclyn M. Winter*. Emerimicins V‒X, 15-Residue Peptaibols Discovered from an Acrenomium sp. Through Integrated Genomic and Chemical Approaches  J. Nat. Prod. 2021, 84, 4, 1113–1126https://doi.org/10.1021/acs.jnatprod.0c01186


  10. Stephanie C Heard , Guangwei Wu*,Jaclyn M. Winter*, Discovery and characterization of a cytochalasan biosynthetic cluster from the marine-derived fungus Aspergillus flavipes CNL-338 J. Antibiot., 2020; 73(11):803-807 https://www.nature.com/articles/s41429-020-00368-0


  11. Guangwei Wu, Guihong Yu, Yunjia Yu, Shuang Yang, Zhongwei Duan, Wei Wang, Yankai Liu, Rilei Yu, Jing Li, Tianjiao Zhu, Qianqun Gu, Dehai Li. Chemoreactive-inspired discovery of influenza A virus dual inhibitor to block hemagglutinin-mediated adsorption and membrane fusion. J. Med. Chem. 2020, 63, 13, 6924–6940. https://pubs.acs.org/doi/10.1021/acs.jmedchem.0c00312


  12. Lin Chen, Guang-Wei Wu, Dong Liu, Wen-Ying Zhuang, Wen-Bing Yin. Trichodermatides E and F from fungus Trichoderma applanatum. J. Asian Nat. Prod. Res. 2019, 21(7):659-665.


  13. Guangwei Wu, Xin Qi, Xiaomei Mo, Guihong Yu, QiangWang, Tianjiao Zhu, Qianqun Gu, Ming Liu, Jing Li, Dehai Li. Structure-based discovery of cytotoxic dimeric tetrahydroxanthones as potential topoisomerase I inhibitors from a marine-derived fungus. Eur J Med Chem., 2018, 148, 268-278. https://doi.org/10.1016/j.ejmech.2018.02.041


  14. Guihong Yu, Guangwei Wu, Zichao Sun, Xiaomin Zhang, Qian Che, Qianqun Gu, Tianjiao Zhu, Dehai Li, Guojian Zhang. Cytotoxic Tetrahydroxanthone Dimers from the Mangrove-Associated Fungus Aspergillus versicolor HDN1009. Mar. Drugs 2018, 16, 335. https://doi.org/10.3390/md16090335


  15. Zhenzhen Zhang, Xueqian He, Guangwei Wu, Congcong Liu, Changjun Lu, Qianqun Gu, Qian Che, Tianjiao Zhu, Guojian Zhang, Dehai Li. Aniline-Tetramic Acids from the Deep-Sea-Derived Fungus Cladosporium sphaerospermum L3P3 Cultured with the HDAC Inhibitor SAHA. J. Nat. Prod., 2018, 81 (7), 1651-1657. https://doi.org/10.1021/acs.jnatprod.8b00289


  16. Guangwei Wu, Jason R. Nielson, Randall T. Peterson, Jaclyn M. Winter Bonnevillamides, Linear Heptapeptides Isolated from a Great Salt Lake-Derived Streptomyces sp. Mar. Drugs 2017, 15, 195. https://doi.org/10.3390/md15070195 


  17. Guangwei Wu, Haichuan Zhou, Peng Zhang, Xiuna Wang, Wei Li, Weiwei Zhang, Xingzhong Liu, Hong-Wei Liu, Nancy P. Keller, Zhiqiang An, Wen-Bing Yin. Polyketide Production of Pestaloficiols and Macrodiolide Ficiolides Revealed by Manipulations of Epigenetic Regulators in an Endophytic Fungus. Org. Lett. 2016, 18, 1832–1835. https://doi.org/10.1021/acs.orglett.6b00562


  18. Gui-Hong Yu, Guang-Wei Wu, Tian-Jiao Zhu, Qian-Qun Gu, De-Hai Li. Cladosins F and G, two new hybrid polyketides from the deep-sea-derived Cladosporium sphaerospermum 2005-01-E3 J. Asian Nat. Prod. Res. 2015 17, 120–124. https://doi.org/10.1080/10286020.2014.940330


  19. Xinhua Ma, Jixing Peng, Guangwei Wu, Tianjiao Zhu, Guoqiang Li, Qianqun Gu, Dehai Li. Speradines B-D, oxygenated cyclopiazonic acid alkaloids from the sponge-derived fungus Aspergillus flavus MXH-X104 Tetrahedron 2015, 71, 3522–3527. https://doi.org/10.1016/j.tet.2015.03.050


  20. 李伟, 吴广畏, 杨玉萍, 尹文兵. 后基因组时代的真菌天然产物发现. 2015, 菌物学报, 5:914-926. DOI:10.13346/j.mycosystema.150098


  21. Guangwei Wu, Guihong Yu, Tibor Kurtán, Attila Mándi, Jixing Peng, Xiaomei Mo, Ming Liu, Hui Li, Xinhua Sun, Jing Li, Tianjiao Zhu, Qianqun Gu, Dehai Li. Xanthone-Chromanone Dimers from the Mangrove-derived Fungus Aspergillus versicolor HDN1009 J. Nat. Prod., 2015, 78 (11), 2691–2698. https://doi.org/10.1021/acs.jnatprod.5b00636


  22. Guangwei Wu, Xinhua Sun, Guihong Yu, Wei Wang, Tianjiao Zhu, Qianqun Gu, Dehai Li. Cladosins A-E, Fungal Hybrid Polyketides from a Deep-Sea Derived Fungus Cladosporium sphaerospermum. J. Nat. Prod. 2014, 77, 270-275. https://doi.org/10.1021/np400833x


  23. Xinhua Sun, Xianglan Kong, Huquan Gao, Tianjiao Zhu, Guangwei Wu, Qianqun Gu, Dehai Li Two new meroterpenoids produced by the endophytic fungus Penicillium sp. SXH-65. Arch. Pharm. Res. 2014, 37, 978–982. https://doi.org/10.1007/s12272-013-0268-2


  24. Aiqun Lin, Guangwei Wu, Qianqun Gu, Tianjiao Zhu, Dehai Li. New Eremophilane-type Sesquiterpenes from an Antarctic Deep-sea Derived Fungus, Penicillium sp. PR19N-1. Arch. Pharm. Res. 2014 37, 839–844. https://doi.org/10.1007/s12272-013-0246-8


  25. Guojian Zhang, Guangwei Wu, Tianjiao Zhu, Tibor Kurtán, Attila Mándi, Jieying Jiao, Jing Li, Xin Qi, Qianqun Gu, Dehai Li. Meroterpenoids with Diverse Ring Systems from the Sponge-Associated Fungus Alternaria alternate JJY-32. J. Nat. Prod., 2013, 76 (10), 1946–1957. https://doi.org/10.1021/np4005757


  26. Guangwei Wu, Aiqun Lin, Qianqun Gu, Tianjiao Zhu, Dehai Li. Four New Chloro-Eremophilane Sesquiterpenes from an Antarctic Deep-Sea Derived Fungus, Penicillium sp. PR19N-1. Mar. Drugs 2013, 11, 1399–1408. https://doi.org/10.3390/md11041399


  27. Guangwei Wu, Hongyan Ma, Tianjiao Zhu, Jing Li, Qianqun Gu, Dehai Li. Penilactones A and B, two novel polyketides from Antarctic deep-sea derived fungus Penicillium crustosum PRB-2. Tetrahedron, 2012, 68, 9745–9749. https://doi.org/10.1016/j.tet.2012.09.038


  28. Guang-Wei Wu, Jin-Ming Gao, Xin-Wei Shi, Qiang Zhang, Shao-Peng Wei, Kan Ding. Microbial Transformations of Diosgenin by the White-Rot Basidiomycete Coriolus versicolor, J. Nat. Prod. 2011, 74, 2095–2101. https://doi.org/10.1021/np2003484


  29. Guang Wei Wu, Xiao Jun Li, Yi Gao, Yuan Jia, Jin Ming Gao. New polyhydroxylated metabolite derived from biotransformation of diosgenin by the white-rot fungus Coriolus versicolor. Chinese Chem. Lett., 2010, 21:446–448.https://doi.org/10.1016/j.cclet.2009.11.018


  30. Ting Dong, Guang-Wei Wu, Xiao-Ning Wang, Jin-Ming Gao, Jian-Guang Chen, Shoei-Sheng Lee Microbiological transformation of diosgenin by resting cells of filamentous fungus, Cunninghamella echinulata CGMCC 3.2716. J. Mol. Catal. B-Enzym. 2010, 67:251–256. https://doi.org/10.1016/j.molcatb.2010.09.001