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成果及论文

英文文章:

2023

1. Lijuan Ma, Nan Li, Jing Wang, Chaofu Ma, Xiaoyan Hu, Mingshuang Li, Zhisheng Wu. Advances in application and innovation of microfluidic platforms for pharmaceutical analysis. TrAC Trends in Analytical Chemistry,2023,160,doi: 10.1016/j.trac.2023.116951IF: 14.908 Q1 B1.

2.Ma, Chaofu; Ma, Lijuan; Wang, Zijian; Li, Nan; Li, Mingshuang; Wang, Jing; Wang, Xiaomeng; Song, Xiao; Yan, Hao; Han, Yanyu; Guan, Yongxia; Yao, Jingchun; Zhang, Guimin; Wu, Zhisheng. Original end-to-end smart diagnosis framework of systematic critical quality attributes meets FDA standards of phytomedicine by biosensor and multi-information fusion coupled with AI algorithm. Green Chemistry 2023, doi:10.1039/D2GC03835HIF: 11.034 Q1 B1.

3. Ma Lijuan, Li Boyi, Ma Jinchen, Wu Chunyuan, Li Nan, Zhou Kailin, Yan Yun, Li Mingshuang, Hu Xiaoyan, Yan Hao, Wang Qi, Zheng Yanfei, Wu Zhisheng. Novel discovery of schisandrin A regulating the interplay of autophagy and apoptosis in oligoasthenospermia by targeting SCF/c-kit and TRPV1 via biosensors. Acta Pharmaceutica Sinica B, 2023, doi: 10.1016/j.apsb.2023.01.004IF: 14.903 Q1 B1

4. Qianqian Li, Jingqi Zeng, Lijuan Ma, Jinyuan Zhu, Fangyu Zhang, Yunan Wei, Mingshuang Li, Lu Yao, Jing Du, Zhisheng Wu. Successive challenge for multi-batch overall pharmaceutical manufacturing control from two-step digital process to OQC strategy by integrated intelligent algorithm. Journal of Industrial Information Integration,2023, 33, doi: 10.1016/j.jii.2023.100454IF: 11.718 Q1


2022

1.  Lijuan Ma, Jing Zhang, Ling Lin, Tuanjie Wang, Chaofu Ma, Xiaomeng Wang, Mingshuang Li, Yanjiang Qiao, Yongxiang Wang, Guimin Zhang, Zhisheng Wu, Data-driven engineering framework with AI algorithm of Ginkgo Folium tablets manufacturing, Acta Pharmaceutica Sinica B, 2022, doi:10.1016/j.apsb.2022.08.011IF: 14.903 Q1 B1.

2. Xiaoyan Hu, Jingqi Zeng, Lijuan Ma, Xiaomeng Wang, Jing Du, Lu Yao, Zhisheng Wu, End-to-end dataflow engineering framework of honey manufacturing from intermediates to process by TAS1R2@AuNPs/SPCE biosensor coupled with quality transfer principle, Fundamental Research, 2022, doi:10.1016/j.fmre.2022.09.029IF: NA NA NA.

2021

1.   Ma Lijuan,Zheng Yanfei,Wang Ji,Li Qianqian,Zeng Jingqi,Wang Zijian,Hou Tingjun,Zhang Yang,Li Mingshuang,Shen Rongmin,Chen Xuemei,Qin Jingbo,Lei Leting,Xia Qing,Wang Qi,Qiao Yanjiang,Wu Zhisheng. Development of MIF/IL-1β biosensors for discovery of critical quality attributes and potential allergic rhinitis targets from clinical real-world data by intelligent algorithm coupled with in vitro and vivo mechanism validation[J]. Biosensors and Bioelectronics,2021,194.

2.   Zhao Na,Ma Lijuan,Wang Kaiyi,Zhang Fangyu,Li Mingshuang,Liu Xiaona,Zhu Mingli,Lu Ying,Song Xiao,Yan Hao,Xiao Wei,Qiao Yanjiang,Wu Zhisheng. NIR robustness model of variable selection investigation of critical quality attributes coupled with different simulate noises by prediction capability and reproducibility.[J]. Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy,2021,267(P2).

3.   Li Qianqian,Zeng Jingqi,Lin Ling,Zhang Jing,Zhu Jinyuan,Yao Lu,Wang Shuying,Du Jing,Wu Zhisheng. Mid-infrared spectra feature extraction and visualization by convolutional neural network for sugar adulteration identification of honey and real-world application[J]. LWT,2021,140.

2020

1.   Qianqian Li,Jingqi Zeng,Ling Lin,Jing Zhang,Jinyuan Zhu,Lu Yao,Shuying Wang,Zhongqing Yao,Zhisheng Wu. Low risk of category misdiagnosis of rice syrup adulteration in three botanical origin honey by ATR-FTIR and general model[J]. Food Chemistry,2020,332.

2.   Ling Lin,Manfei Xu,Lijuan Ma,Jingqi Zeng,Fangyu Zhang,Yanjiang Qiao,Zhisheng Wu. A rapid analysis method of safflower ( Carthamus tinctorius L.) using combination of computer vision and near-infrared[J]. Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy,2020,236.

3.   Lijuan Ma,Daihan Liu,Chenzhao Du,Ling Lin,Jinyuan Zhu,Xingguo Huang,Yuan Liao,Zhisheng Wu. Novel NIR modeling design and assignment in process quality control of Honeysuckle flower by QbD[J]. Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy,2020,242.

4.   Liu, X., Xiaoqing, C., Li, K., Wang, X., Lin, Z., Wu, Z., & Qiusheng, Z. (2020). Geographical authenticity evaluation of Mentha haplocalyx by LIBS coupled with multivariate analyses. Plasma Science and Technology. doi:10.1088/2058-6272/ab7edaIF: 1.842 Q3 B3

5.   Qianqian Li, Zhisheng Wu,Ling Lin,Jingqi Zeng,Jixiong Zhang,Hong yan&Shungeng Min. High-level Fusion Coupled with Mahalanobis Distance Weighted (MDW)Method for Multivariate Calibration.[J].Scientific Reports,(2020)10:5478

6.   Lijuan Ma,Yang Li,Leting Lei,Jingqi Zeng,Jing Zhang,Yanjiang Qiao,Zhisheng Wu. Real-time process quality control of ramulus cinnamomi by critical quality attribute using microscale thermophoresis and on-line NIR[J]. Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy,2020,224.117463

7.   Zeng J,Zhou Z,Liao Y, et al. System Optimisation Quantitative Model of On-line Nir: a Case of Glycyrrhiza Uralensis Fisch Extraction Process[J]. Phytochemical Analysis, 2020,1-7.

2019

1. Lijuan Ma, Yanfang Peng, Yanling Pei, Jingqi Zeng, Haoran Shen, Junjie Cao, Yanjiang Qiao & Zhisheng Wu. Systematic discovery about NIR spectral assignment from chemical structural property to natural chemical compounds[J]. Scientific reports, 2019, 9(1):9503.

2.   Chenzhao Du, Shengyun Dai, Anbang Zhao, Yanjiang Qiao, Zhisheng Wu. Optimization of PLS modeling parameters via quality by design concept for Gardenia jasminoides Ellis using online NIR sensor. Spectrochimica Acta Part A Molecular & Biomolecular Spectroscopy, 2019, 222, 117267

2018

1.  Ma Lijuan, Zhou Luwei, Xu Manfei, Huang Xingguo, Zhang Qiao, Dai Shengyun, Qiao Yanjiang*, Wu Zhisheng*. Investigation of the distributional homogeneity on chlorpheniramine maleate tablets using NIR-CI[J]. Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2018, 11(5) 204:783-790.

2.  Liu Xiaona, Wang Shifeng, Wang Zhaoyi, Zheng Qiusheng, Li Defang*, Wu Zhisheng*. Deoxyschizandrin loaded liposomes on the suppression lipid accumulation in 3T3-l1 adipocytes[J]. Molecules, 2018, 9, 23(9):2158.

3.  Zhao Na, Ma Lijuan, Huang Xingguo, Liu Xiaona, Qiao Yanjiang*, Wu Zhisheng*. Pharmaceutical analysis model robustness from Bagging-PLS and PLS using systematic tracking mapping[J]. Frontiers in Chemistry, 2018, 7(6) 6:262.

4.  Dai Shengyun, Pan Xiaoning, Ma Lijuan, Huang Xingguo, Du Chenzhao, Qiao Yanjiang*, Wu Zhisheng*. Discovery of the linear region of near infrared diffuse reflectance spectra using the kubelka-munk theory[J]. Frontiers in Chemistry, 2018, 5(7) 6:154.

5.  Chenzhao Du, Shengyun Dai, Yanjiang Qiao*, Zhisheng Wu*. Error propagation of partial least squares for parameters optimization in NIR modeling[J]. Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2018, 5, 192:244-250.

2017

1.  Jing Li, Yanjiang Qiao, Zhisheng Wu*. Nanosystem trends in drug delivery using quality-by-design concept[J]. Journal of Controlled Release, 2017,6(28):256:9-18.

2.  Xiaosu Miao, Qingyu Cui, Honghui Wu, Yanjiang Qiao, Yanfei Zheng*, Zhisheng Wu*. New sensor technologies in quality evaluation of Chinese materia medica: 2010–2015[J], Acta Pharmaceutica Sinica B, 2017,3(7) 2:137-145.

3.  Yu Fulai, Zhao Na, Wu Zhi-Sheng, Huang Mei, Zhang*, Ying-Bo, Hu Xuan, Chen, Xiao-Lu, Huang, Lu-Qi, Pang, Yu-Xin*. NIR rapid assessments of blumea balsamifera (Ai-na-xiang) in China[J], Molecules, 2017, 10,22(10):1730.

4.  Miao Xiao-Su, Cui Qing-Yu, Wang Zhao-Yi, Liu Xiao-Na, Zhao An-Bang, Qiao Yan-Jiang*, Wu Zhi-Sheng*. Advance in quality assessment of Chinese materia medica using microscopic and morphological methods[J]. Chinese Journal of Natural Medicines, 2017, 9(15):653-663.

5.  Xiaona Liu, Shifeng Wang, Zhisheng Wu, Zhaoyi Wang, Yanjiang Qiao*. Scientific fusion of liver-based therapy of traditional Chinese medicine theory and modern deoxyschizandrin nano-delivery system on the hepatoprotective activity[J]. Journal of Controlled Release, 2017, 8(10)259:149-150.

6.  WU Zhi-sheng, LIU Xiao-na, TAN Peng, PEI Yan-ling, DAI Xing-xing, QIAO Yan-jiang*. Research on steaming procedure of aconite root with FTIR and two- dimensional IR correlation spectroscopy. Spectroscopy and spectral analysis, 2017, 37(06):1745-1748.

7.  Xiaoying Li1, Zhisheng Wu1, Xin Feng, Shanshan Liu, Xiaojie Yu, Qun Ma, Yanjiang Qiao. Quality-by-Design: Multivariate model for multicomponent quantification in refining process of honey. Phcog Mag, 2017(13):193-8. (1Co-first authors).

2016

1.  Manfei Xu, Shengyun Dai, Zhisheng Wu*, Xinyuan Shi, Yanjiang Qiao*. Rapid analysis of dyed safflowers by color objectification and pattern recognition methods. Journal of Traditional Chinese Medical Sciences, 2016, 3(4):234–241.

2. Manfei Xu,Chenzhao Du,Na Zhang,Xinyuan Shi,Zhisheng Wu,Yanjiang Qiao.Color spaces of safflower(Carthamus tinctorius L.) for quality assessment[J].Journal of Traditional Chinese Medical Sciences,2016,3(03):168-175.

3.  Manfei Xu, Luwei Zhou, Qiao Zhang, Zhisheng Wu*, Xinyuan Shi, Yanjiang Qiao, Near-infrared chemical imaging for quantitative analysis of chlorpheniramine maleate and distribution homogeneity assessment in pharmaceutical formulations[J]. Innov. Opt. Health Sci, 2016, 9(4):1-9.

4.  Na Zhao, Zhisheng Wu*, Yaqian Cheng, Xinyuan Shi, Yanjiang Qiao*. MDL and RMSEP assessment of spectral pretreatments by adding different noises in calibration/validation datasets. Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy 2016, (163):20–27.

5.  Zhisheng Wu, Guang Wan, Cuicui Su, Meiwan Chen, Xinyuan Shi, Dehai Liang*, Yanjiang Qiao*, Nano-analysis of triptolide liposomes for potential therapy of prostate cancer,Nanomedicine: Nanotechnology. Biology and Medicine, 2016, 12(2):528-528.

6.  Zheng Zhou, Yang Li, Xinyuan Shi, Zhisheng Wu*, Yanjiang Qiao*. Comparison of ensemble strategies in on-line NIR for monitoring the extraction process of Pericarpium Citri Reticulatae based on different variable selections. Planta Medica, 2016, 82(2):154-162.

7.  Luwei Zhou, Manfei Xu, Zhisheng Wu*, Xinyuan Shi, Yanjiang Qiao*, PAT: From Western solid dosage forms to Chinese materia medica preparations using NIR-CI. Drug Testing and Analysis, 2016, 8(1):71-85.

2015

1.  Zhao Na, Wu Zhi-sheng, Zhang Qiao, Shi Xin-yuan, Ma Qun, QiaoYan-jiang*. Optimization of parameter selection for partial least squares model development[J]. Scientific Reports, 2015,7(13):5.

2.  Xiaoning Pan, Feiyan Li, Zhisheng Wu*, Qiao Zhang, Zhaozhou Lin, Xinyuan Shi and Yanjiang Qiao. Near infrared spectroscopy model development and variable importance in projection assignment of particle size and lobetyolin content of Codonopsis radix. J Near Infrared Spec, 2015, 23(5):327–335.

3.  Liu Xiaona, Huang Jianmei, Wu Zhisheng*, Zhang Qiao, Shi Xinyuan, Zhao Na,Jia Shuaiyun, Qiao Yanjiang*, Microanalysis of multi-element in Juncus effusus L. by LIBS Technique. plasma science and technology, 2015, 17(11): 904-906.

4.  Xiaoning Pan, Yang Li, Zhisheng Wu*, Qiao Zhang, Zhou Zheng, Xinyuan Shi, Yanjiang Qiao*, A online NIR sensor for the pilot-scale extraction process in fructus aurantii coupled with single and ensemble methods. Sensors, 2015, 15(4):8749-8763.

5.  Xiaona Liu, Qun Ma, Shanshan Liu, Xinyuan Shi, Zhisheng Wu*, Yanjiang Qiao*. Monitoring As and Hg variation in An-Gong-Niu-Huang Wan (AGNH) intermediates in a pilot scale blending process using laser-induced breakdown spectroscopy. Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2015, 151, 547-552.

6.  Yanling Pei, Zhisheng Wu*, Xinyuan Shi, Xiaoning Pan, Yanfang Peng, Yanjiang Qiao*. NIR assignment of Magnolol by 2D-COS technology and model application in Huoxiangzhengqi Oral Liquid. Spectroscopy and Spectral Analysis, 2015, 35(8):2119.

7.  Yanling Pei, Zhisheng Wu*, Xinyuan Shi, Xiaoning Pan, Yanfang Peng, Yanjiang Qiao*. NIR assignment of Isopsoralen by 2D-COS technology and model application in Yunkang Oral Liquid[J]. Innov. Opt. Health Sci, 2015, 8(6):1-8.

8.  Yang Li, Mingye Guo, Xinyuan Shi, Zhisheng Wu*, Jianyu Li, Bing Xu, Qun Ma and Yanjiang Qiao*. On-line NIR analysis for multi-ingredients and multi-phases extraction in Radix Glycyrrhizae coupled with MWPLS and SiPLS models. Chinese medicine, 2015, 10(1):1-10.

9.  Zhisheng Wu, Xinyuan Shi*, Guang Wan, Manfei Xu, Yanjiang Qiao*. MEMS- NIR validation of different sampling modes and sample sets coupled with multiple models, Planta Medica, 2015, 81, 167-174.

10.  Zisheng Wu, Luwei Zhou, Bing Xu, Shengyun Dai, Xinyuan Shi, Yanjiang Qiao*. Evaluation of NIR spectromicroscopy for the analysis of glycyrrizhic acid in licorice. Chinese Journal of Natural Medicines, 2015, 13(4).

11.  Yifei Wang, Zhisheng Wu*, Zhaoyi Wang, Manfei Xu, Xinyuan Shi, Yanjiang Qiao*. Rapid analysis of spatial distribution of PVPP and hardness of Yinhuang dispersible tablets by NIR-CI. J. Innov. Opt. Health Sci. 2015, 8(5):1-7.

12.  Yang Li, Zhisheng Wu*, Qun Ma, Xinyuan Shi, Yanjiang Qiao*. Near-infrared for on-line determination of quality parameter of Sophora japonica L. (formula particles): From lab investigation to pilot-scale extraction process. Pharmacognosy Magazine, 2015, 11, 8-13.

2014

1.  Xiaona Liu, Qiao Zhang, Zhisheng Wu*, Xinyuan Shi, Na Zhao, Yanjiang Qiao*. Rapid elemental analysis and provenance study of blumea balsamifera DC using laser-induced breakdown spectroscopy. Sensors, 2014, 15(1):642-655.

1.  Zhisheng Wu*, Guoqing Ouyang, Xinyuan Shi, Qun Ma, Guang Wan, Yanjiang Qiao*. Absorption and quantitative characteristics of C-H bond and O-H bond of NIR. Optics and Spectroscopy, 2014, 117, 703-709.

2.  Zhisheng Wu, Min Du, Xinyuan Shi, Bing Xu, Yanjiang Qiao*. Robust PLS prediction model for Saikosaponin A in Bupleurum chinense DC. coupled with granularity-hybrid calibration set. Journal of Analytical Methods in Chemistry, 2014, (2015):1-7.

3.  Zhisheng Wu*, Xinyuan Shi, Zhao N, Y Pei, Manfei Xu, Luwei Zhou, Yang Li, Yanjiang Qiao*. Estimation of multivariate detection limits of four quality parameters in licorice using MEMS–NIR spectrometry coupled with two sampling accessories[J]. Journal of Innovative Optical Health Sciences 2014, 8(4):1-10.

4.  Luwei Zhou, Zhisheng Wu*, Xinyuan Shi, Manfei Xu, Bing Xu, Yanjiang Qiao*. Rapid discrimination of chlorpheniramine maleate and assessment of its surface content uniformity in a pharmaceutical formulation by NIR-CI coupled with statistical measurement. Spectroscopy, 2014,(5):1-9.

5.  Luwei Zhou, Zhisheng Wu*, Xinyuan Shi, Manfei Xu, Qiao Zhang, Yanjiang Qiao*. The research on NIR-CI parameters optimization of chlorpheniramine maleate tablets based on binary image and statistical measurement[J]. Spectroscopy and Spectral Analysis, 2014, 34(10):2821-2826.

6.  Yang Li, Zhisheng Wu*, Xiaoning Pan, Xinyuan Shi, Mingye Guo, Bing Xu, QIAO Yan-jiang*. Applications and prospects of On-Line near infrared spectroscopy technology in manufacturing of chinese materia medica[J]. Spectroscopy and Spectral Analysis, 2014, 10, 2632-2638.

7.  Yanling Pei, Zhisheng Wu*, Xinyuan Shi, Luwei Zhou, Yanjiang Qiao*. Rapid assessment of critical quality attributes of Chinese materia medica (Ⅱ): strategy of NIR assignment[J]. Spectroscopy and Spectral Analysis 2014, 34, 2391-2396.

8.  Zhao Chen, Zhisheng Wu*, XinYuan Shi, Bing Xu, Na Zhao, Yanjiang Qiao*. A study on model performance for ethanol precipitation process of lonicera japonica by NIR based on Bagging-PLS and Boosting-PLS algorithm. Chinese Journal of Analytical Chemistry, 2014,11,1679-1686.

2013

1.  Zhisheng Wu, Chenglin Sui, Bing Xu, Lu Ai, Qun Ma, Xinyuan Shi, Yanjiang Qiao*. Multivariate detection limits of on-line NIR model for extraction process of chlorogenic acid from Lonicera japonica. Journal of Pharmaceutical and Biomedical Analysis, 2013, 77, 16-20.

2.  Yanfang Peng, Xinyuan Shi, Luwei Zhou, Yanling Pei, Yang Li, Zhisheng Wu*, Qiaoyan Jiang*. Multivariate detection limit of baicalin in Qingkailing injection based on four NIR technology type. Spectroscopy and Spectral Analysis, 2013, 33(9):2363-2368.

3.  Zhisheng Wu, Yanfang Peng, Wei Chen, Bing Xu, Qun Ma, Xinyuan Shi*, Yanjiang Qiao*. NIR spectroscopy as a process analytical technology (PAT) tool for monitoring and understanding of a hydrolysis process[J]. Bioresource Technology, 2013,6(01) 137:394-399.

4.  Zhisheng Wu, Qun Ma, Zhaozhou Lin, Yanfang Peng, Lu Ai, Xinyuan Shi*, Yanjiang Qiao*. A novel model selection strategy using total error concept[J]. Talanta, 2013,3(30) 107:248-254.

2012

1.  Zhisheng Wu, Min Du, Bing Xu, Zhaozhou Lin, Xinyuan Shi, Yanjiang Qiao*. Absorption characteristics and quantitative contribution of overtones and combination of NIR: Method development and validation. Journal of Molecular Structure, 2012,10(19):97-102.

2.  Zhisheng Wu, Ou Tao, Xinxing Dai, Xinyuan Shi, Yanjiang Qiao*. Monitoring blending process of Yinhuang powder by near infrared chemical imaging. Vibrational Spectroscopy, 2012,63, 373-379.

3.  Zhisheng Wu, Min Du, Chenglin Sui, Xinyuan Shi, Yanjiang Qiao*. Development and validation of PLS model using low-concentration calibration range: rapid analysis of solution from Lonicera japonica in ethanol precipitation process. Analytical Methods, 2012, 4, 1084-1088.

4.  Zhisheng Wu, Min Du, Chenglin Sui, Xinyuan Shi, Yanjiang Qiao*.Validation of a NIR quantification method for the determination of chlorogenic acid in Lonicera japonica solution in ethanol precipitation process. Journal of Pharmaceutical and Biomedical Analysis, 2012, 62, 1-6.

5.  Zhisheng Wu, Ou Tao, Wei Cheng, Lu Yu, Xinyuan Shi, Yanjiang Qiao*. Visualizing excipient composition and homogeneity of compound liquorice tablets by near-infrared chemical imaging. Spectrochimica Acta Part A, 2012, 86, 631-636

2011

1.  Zhisheng Wu, Ou Tao, Wei Cheng, Lu Yun, Xinyuan Shi, Yanjiang Qiao*. Research on spatial distribution and composition uniformity of Rukuaixiao tablets intermediate by spectral imaging. Chinese Journal of Analytical Chemistry, 2011, 5, 628-634.

2010

1.  Zhenfeng Hong1, Wang Chen1, Jinyan Zhao1, Zhisheng Wu1, JianHeng Zhou, Tianjiao Li and Juan Hu*. Hepatoprotective effects of Rubus aleaefolius poir and identification of its active constituents. Journal of Ethnopharmacology, 2010, 129, 267–272. (1Co-first authors).

2009

1.  Juan Hu1 and Zhisheng Wu1, Jingjing Yan, Wensheng Pang, Dehai Liang*, Xiaojie Xu*. A promising approach for understanding the mechanism of Traditional Chinese Medicine by aggregation morphology. Journal of Ethnopharmacology, 2009, 123, 267–274. (1Co-first authors).

2.  Zhisheng Wu, Jing Zhang, Wang Chen, Juan Hu*. Studies on the aggregation and interaction of Daidzin with bovine serum albumin by fluorescence spectrum and laser light scattering. acta chim. Sinica, 2009, 67(14):1609-1614.

 

 文章:

2022

1.    彭严芳,王君,吴志生,刘晓娜,乔延江.丹参酮ⅡA和隐丹参酮近红外光谱的2D-COS解析及其在丹参酮提取物近红外模型中应用[J].光谱学与光谱分析,2022,42(06):1781-1785.

2021

1.    雷乐庭,马丽娟,魏宇楠,林玲,朱金媛,曾敬其,张静,李倩倩,姚璐,吴志生.中药大品种制造关键质量属性表征:化学与功效属性结合的同仁牛黄清心丸模块化辨识研究[J].中国中药杂志,2021,46(07):1606-1615.

2.   魏宇楠,黄兴国,曾敬其,李倩倩,马丽娟,雷乐庭,张瀚,姚璐,王淑英,吴志生.中药大品种制造关键质量属性表征:水分含量化学属性的同仁牛黄清心丸NIR现场检测方法研究[J].中国中药杂志,2021,46(07):1592-1597.

3.   朱金媛,曾敬其,李倩倩,马丽娟,陆影,张瀚,郑燕飞,吴春媛,吴志生.中药大品种制造关键质量属性表征:特征成分化学属性的黄精赞育胶囊质量控制方法研究[J].中国中药杂志,2021,46(07):1629-1635.

4.   张静,祝明利,林玲,曾敬其,彭潇,姚仲青,李敏,关永霞,吴志生.中药大品种制造关键质量属性表征:粉末物理属性的银杏叶提取物物料质量控制方法研究[J].中国中药杂志,2021,46(07):1622-1628.

5.   曾敬其,张静,张芳语,张瀚,祝明利,陆影,关永霞,吴志生.中药大品种制造关键质量属性表征:沸腾时间状态属性的提取过程在线NIR质量控制研究[J].中国中药杂志,2021,46(07):1644-1650.

6.   祝明利,张芳语,张瀚,陆影,曾敬其,张静,马朝富,王文哲,姚仲青,吴志生.中药大品种制造关键质量属性表征:粉末与颗粒物理属性的苏黄止咳胶囊中间体过程质量控制方法研究[J].中国中药杂志,2021,46(07):1636-1643.

7.   张芳语,林玲,曾敬其,祝明利,陆影,张瀚,李倩倩,马丽娟,姚璐,吴志生.中药大品种制造关键质量属性表征:空间分布均匀度质量属性的同仁牛黄清心丸贵细药混合过程控制可视化方法研究[J].中国中药杂志,2021,46(07):1585-1591.

8.    林玲,张芳语,张静,马朝富,王文哲,雷乐庭,朱金媛,姚仲青,李敏,吴志生.中药大品种制造关键质量属性表征:空间分布均匀度属性的银杏叶片质量控制可视化方法研究[J].中国中药杂志,2021,46(07):1616-1621.

9.    曾敬其,李倩倩,马丽娟,祝明利,毛宁,伍振峰,姚璐,王淑英,吴志生.中药大品种制造关键质量属性表征:质构感官属性的同仁牛黄清心丸质量控制方法研究[J].中国中药杂志,2021,46(07):1598-1605.

10.  陆影,曾敬其,马金辰,戴幸星,朱金媛,张芳语,祝明利,张瀚,姚璐,王淑英,左艳,吴志生.中药大品种制造关键质量属性表征:滋味质量属性的小儿感冒口服液口感配方优化策略研究与应用[J/OL].中国中药杂志:1-9.

11.    刘南岑,耿立冬,马丽娟,吴志生.中药制造领域近红外光谱技术的专利技术进展和趋势[J].中草药,2021,52(21):6768-6774.

2020

1.    马丽娟,暴正瀚,雷乐庭,王逸飞,朱振宇,王济,王琦,乔延江,郑燕飞,吴志生.基于数据挖掘和网络药理学的新冠肺炎预防方药组方规律和作用机制研究[J].世界科学技术-中医药现代化,2020,22(03):566-572.

2.    廖源,吴建华,马丽娟,张静,雷乐庭,李玲孺,李英帅,王琦,乔延江,王济,吴志生.基于网络药理学的中期诊疗方干预新型冠状病毒肺炎(COVID-19)作用机制研究[J].中草药,2020,51(07):1776-1784.

2019

1.    曾敬其,朱金媛,雷乐庭,林玲,张杰,吴志生,朱振宇,王逸飞,李文华.QbD理念的医院制剂创研:妇科止痒洗剂全程工艺优化策略[J].中国中药杂志,2019,44(20):4342-4349.

2.    吴志生,石涵芬,曾敬其,张静,廖源,黄兴国,郑燕飞,王济,王琦.QbD理念的名医名方创研:脱敏定喘颗粒工艺优化研究[J].中国中药杂志,2019,44(20):4322-4328.

3.    王逸飞,朱振宇,吴志生,李文华.QbD理念的中药缓控释制剂的设计与研发研究[J].中国中药杂志,2019,44(20):4317-4321.

4.    黄兴国,张静,杜文慧,江宗岳,杨继,吴志生.QbD理念的经典名方研究:四物汤加减方的提取工艺优化研究[J].中国中药杂志,2019,44(20):4329-4335.

2018

1.  赵安邦,杜晨朝,吴志生,郑燕飞,王济,何文静,王琦.过敏康颗粒质量控制方法研究[J].中华中医药杂志,2018,33(03):1036-1040.

2017

1.  杜晨朝,赵安邦,吴志生,乔延江.近红外光谱结合不同变量筛选方法用于金银花提取过程中绿原酸量的在线监测[J].中草药,2017,48(16):3317-3321.

2.  吴志生,刘晓娜,谭鹏,裴艳玲,戴幸星,乔延江.基于 2D-COS 红外光谱的附子炮制过程时序段解析研究[J].光谱学与光谱分析,2017,37(06):1745-1748.

3.  王逸飞,章烨雯,王景雁,林红梅,徐铃燕,谭鹏,吴志生,吴清.基于近红外化学成像技术的市售凝胶贴膏空间分布均匀性评价方法研究[J]. 中华中医药杂志,2017,32(04):1830-1832.

4.  刘晓娜,郑秋生,车晓青,吴志生,乔延江.基于 QbD 理念的安宫牛黄丸整体混合终点评价方法研究[J].中国中药杂志,2017,42(06):1083-1088.

2016

1.  杜晨朝, 吴志生, 赵娜, 周正, 史新元, 乔延江. 基于两类误差检测理论金银花提取过程的MEMS-NIR在线分析建模方法研究[J]. 中国中药杂志, 2016, (19): 3563-3568.

2.  吴志生,徐冰,王耘,史新元,乔延江.朝向过程系统工程的中药制药工业发展战略[J].中华中医药杂志,2016,31(09):3417-3419.

3.  徐曼菲,吴志生,刘晓娜,史新元,乔延江.从辨色论质谈中药质量评价方法[J].中国中药杂志,2016,41(02):177-181.

2015

1.  周正,吴志生,史新元,王佳茜,乔延江.Bagging-PLS 的黄柏中试提取过程在线近红外质量监测研究[J].世界中医药,2015,10(12):1939-1942.

2.  裴艳玲,吴志生,史新元,潘晓宁,彭严芳,乔延江.厚朴酚近红外光谱的 2D-COS 解析及其在藿香正气口服液 模型中应用 [J].   光谱学与光谱分析,2015,35(08):2119-2123.

3.  吴志生,史新元,徐冰,戴幸星,乔延江.中药质量实时检测:NIR 定量模型的评价参数进展[J].中国中药杂志,2015,40(14):2774-2781.

4.  吴志生,杜敏,潘晓宁,赵娜,史新元,乔延江.硫磺熏蒸的葛根横纵截面快速判别分析[J].中国中药杂志,2015,40(12):2336-2339.

5.  刘晓娜,史新元,贾帅芸,赵娜,吴志生,乔延江.基于LIBS 技术对4种珍宝藏药快速多元素分析[J].中国中药杂志,2015,40(11):2239-2243.

6.  刘晓娜,张乔,史新元,吴志生,乔延江.基于 LIBS 技术的树脂类药材快速元素分析及判别方法研究[J].中华中医药杂志,2015,30(05):1610-1614.

7.  吴志生,杜敏,潘晓宁,史新元,乔延江.粒径对多类中药材 NIR 频谱区的检测研究[J].中国中药杂志,2015,40(02):287-291.

2014

1.  周璐薇,吴志生,史新元,裴艳玲,乔延江.中药关键质量属性快速评价:近红外化学成像可视化技术[J].世界科学技术-中医药现代化,2014,16(12):2568-2574.

2.  刘晓娜,史新元,贾帅芸,赵娜,吴志生,乔延江.基于 LIBS 技术的藏药佐太快速元素分析研究[J].世界科学技术-中医药现代化,2014,16(12):2582-2585.

3.  陈昭,吴志生,史新元,徐冰,赵娜,乔延江.Bagging 偏最小二乘和 Boosting 偏最小二乘算法的金银花醇沉过程近红外光谱定量模型预测能力研究[J].分析化 学,2014,42(11):1679-1686.

4.  裴艳玲,吴志生,史新元,潘晓宁,刘晓娜,乔延江.基于辛甘化阳,酸甘化阴思想的桂枝- 白芍药对配比的液质联用分析[J]. 世界科学技术- 中医药现代化,2014,16(10):2180-2184.

5.  李洋,吴志生,潘晓宁,史新元,郭明晔,徐冰,乔延江.在线近红外光谱在我国中药研究和生产中应用现状与展望[J].光谱学与光谱分析,2014,34(10):2632-2638.

6.  周璐薇,吴志生,史新元,徐曼菲,张乔,乔延江.基于二值化图像结合像元统计法的扑 尔敏 片剂 近红外 成像 检测 参数 优化 研究[J]. 光谱 学与 光谱分析,2014,34(10):2821-2826.

7.  李洋,吴志生,史新元,潘晓宁,张乔,乔延江.中试规模和不同提取时段的黄芩配方颗粒质量参数在线NIR 监测研究[J].中国中药杂志,2014,39(19):3753-3756.

8.  裴艳玲,吴志生,史新元,周璐薇,乔延江.中药关键质量属性快速评价(Ⅱ):NIR光谱解析策略例证[J].光谱学与光谱分析,2014,34(09):2391-2396.

9.  彭严芳,史新元,李洋,周璐薇,裴艳玲,华国栋,吴志生,乔延江.基于多变量检测限的模型变量筛选方法研究 [J].世界科学技术-中医药现代化,2014,16(05):960-965.

2013

1.  隋丞琳,林兆洲,吴志生,徐冰,李洋,史新元,乔延江.药渣粒径对中药提取过程在线检测取样系统影响的模拟研究[J].分析化学,2013,41(12):1899-1904.

2.  陈昭,林兆洲,吴志生,乔延江.小波变换在 NIR 定量模型中的应用[J].世界中医药,2013,8(11):1273-1276+1279.

3.  刘晓娜,吴志生,乔延江.LIBS 快速评价产品质量属性的研究进展及在中药的应用前景[J].世界中医药,2013,8(11):1269-1272.

4.  杜敏,吴志生,巩颖,史新元,华国栋,乔延江.基于近红外光谱技术的道地山药快速无损分析[J].世界中医药,2013,8(11):1277-1279.

5.  彭严芳,史新元,周璐薇,裴艳玲,李洋,吴志生,乔延江.基于四种 NIR 仪器类型的清开灵注射液中黄芩苷成分的多变量检测限研究[J]. 光谱学与光谱分析,2013,33(09):2363-2368.

 2012及之前

1.  杜敏,吴志生,林兆洲,隋丞琳,史新元,乔延江.光程对清开灵注射液中黄芩苷近红外定量模型的影响[J].药物分析杂志,2012,32(10):1796-1800.

2.  乔延江,杜敏,史新元,吴志生,徐冰.欧盟制药工业近红外光谱技术应用、申报和变更资料要 求指南(草案 )[J]. 世界科学技术 (中医药现代化),2012,14(04):1933-1943.

3.  隋丞琳,吴志生,林兆洲,徐冰,杜敏,史新元,乔延江.样本数据重复性对 NIR 校正模型的影响[J].中国中药杂志,2012,37(12):1751-1754.

4.  吴志生,杨彩媚,韩静,林埔,张宽,胡娟.动态光散射法研究中药注射剂的分子形态[J].中国民族民间医药,2012,21(09):58-60.

5.  吴志生. 中药过程分析中 NIR 技术的基本理论和方法研究[D].北京中医药大学,2012.

6.  吴志生,史新元,隋丞琳,杜敏,彭严芳,乔延江.清开灵注射液中间体银黄液中黄 芩苷含量近红外测定方法 的建立和验证 [J].   中华中医药杂志,2012,27(04):1021-1024.

7.  吴志生. 清开灵注射液中间体银黄液中黄芩苷含量近红外测定方法的建立和验证[A]. 中华中医药学会、《中华中医药杂志》社.第三届全国中医药博士生优秀论文颁奖会议论文集[C].中华中医药学会、《中华中医药杂志》社:《中华中医药杂志》编辑部,2012:4.

8.  王运丽,史新元,吴志生,程伟,乔延江.基于氯化铵溶液的近红外在线定量分析方法的建立[J].中国实验方剂学杂志,2012,18(01):43-47.

9.  吴志生,陶欧,程伟,郁露,史新元,乔延江.基于光谱成像技术的乳块消素片活性成分空间分布及均匀性研究[J].分析化学,2011,39(05):628-634.

10.  吴志生, 章靓, 陈旺, 胡娟. 激光光散射与荧光光谱法研究大豆苷与牛血清白蛋白作用及聚集态[J]. 化学学报, 2009, 67(14): 1609-1614.

11.  吴志生, 庞文生, 黄美霞, 章靓, 陈旺, 胡娟. 银杏叶提取物分子聚集形态(英文)[J]. 天然产物研究与开发, 2009, 21(06): 939-942+959.