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成果及论文

(1) Yang Sun, Fei Gao, Cai Yang, Yingying Li, Cheng Jin, Sitao Xie, Cheng Lv, Ding Ding, Da Han, Juan Li, Ruowen Wang*, Weihong Tan*. ‘Construction of Bispecific Aptamer-Drug Conjugate by a Hybrid Chemical Biological Approach’; Bioconjugate. Chem. 2020, 31, 1289-1294.

(2) Kaiming Chen, Jie Zhou, Zhentao Shao, Jia Liu, Jia Song, Ruowen Wang*, Juan Li*, Weihong Tan*. ‘Aptamers as Versatile Molecular Tools for Antibody Production Monitoring and Quality Control’; J. Am. Chem. Soc. 2020, 142, 12079-12086.

(3) Jianmei Zou, Cheng Jin, Ruowen Wang, Hailan Kuai, Lili Zhang, Xiaobing Zhang, Juan Li, Liping Qiu, Weihong Tan*. ‘Fluorinated DNA Micelles: Synthesis and Properties’; Anal. Chem. 2018, 90, 6843-6850. 

(4) Cheng Jin, Xiaojing Liu, Huarong Bai, Ruowen Wang, Jie Tan, Xuehui Peng, Weihong Tan*. ‘Engineering Stability-Tunable DNA Micelles Using Photocontrollable Dissociation of an Intermolecular G-Quadruplex’; ACS Nano. 2017, 11, 12087-12093.

(5) RuoWen Wang, Cheng Jin, Xiaoyan Zhu, Liyi Zhou, Wenjing Xuan, Yuan Liu, Qiaoling Liu, and Weihong Tan*. Artificial Base zT as Functional “Element” for Constructing Photoresponsive DNA Nanomolecules’; J. Am. Chem. Soc. 2017, 139, 9104-9107

(6) Cheng Jin, Ting Fu, RuoWen Wang*, Hui Liu, Jiamei Zou, Zilong Zhao, Mao Ye, Xiaobing Zhang and Weihong Tan*. ‘Fluorinated molecular beacons as functional DNA nanomolecules for cellular imaging’; Chem. Sci. 2017, 8, 7082-7086. 

(7) RuoWen Wang*, Danqing LuHuarong BaiCheng Jin, Guobei Yan, Mao Ye, Liping Qiu, Rongshan Chang, Cheng Cui, Hao Liang and Weihong Tan*. ‘Using modified aptamers for site specific protein–aptamer conjugations’; Chem. Sci. 2016, 7, 2157-2161.

(8) RuoWen Wang, Chunming Wang, Yang Cao, Zhi Zhu, Chaoyong Yang, Jianzhong Chen, Feng-Ling Qing and Weihong Tan*. ‘Trifluoromethylated Nucleic Acid Analogues Capable of Self-Assembly through Hydrophobic Interactions’; Chem. Sci. 2014, 5, 4076-4081. 

(9) Hao Liang, Xiao-Bing Zhang, Yifan Lv, Liang Gong, RuoWen Wang, Xiaoyan Zhu, Ronghua Yang and Weihong Tan*. ‘Functional DNA-Containing Nanomaterials: Cellular Applications in Biosensing, Imaging, and Targeted Therapy’; Acc. Chem. Res. 2014, 47, 1891-1901. 

(10) RuoWen Wang, Guizhi Zhu, Lei Mei, Yan Xie, Mao Ye, Feng-Ling Qing and Weihong Tan*. ‘Automated and Modular Synthesis of Aptamer-Drug Conjugates for Targeted Drug Delivery’; J. Am. Chem. Soc. 2013, 136, 2731-2734.

(11) Ruo-Wen Wang and Barry Gold*. “A Facile Synthetic Approach to 7-Deazaguan-ine Nucleosides via a Boc Protection Strategy”; Org. Lett., 2009, 11, 2465–2468.

(12) Ruo-Wen Wang, Xiao-Long Qiu, Mikael Bols, Fernando Ortega Caballero and Feng-Ling Qing*Synthesis and Biological Evaluation of Glycosidase Inhibitors:gem-Difluoro-Methylenated Nojirimycin Analogues’; J. Med. Chem. 2006; 49, 2989.  

(13) Ruo-Wen Wang, Jun Xu说明: ?code=200B, Oscar Lopez说明: ?code=200B, Mikael Bols, Feng-Ling Qing*.  ‘Difluoromethylenated PolyhydroxylatedPyrrolidines: Facile Synthesis, Crystal Structure and Biological Evaluation’; Future Medicinal Chemistry 2009, 1, 991-997.

(14) Ruo-Wen Wang and Feng-Ling Qing*. ‘Highly Stereocontrolled Synthesis of gem-Difluoromethylenated Azasugars: D- and L-1,4,6-Trideoxy-4,4-difluoronojirimycinOrg. Lett. 2005, 7, 2189-2192.