40224
当前位置: 首页   >  成果及论文
成果及论文

荣誉奖项

第二十二届施维雅(SERVIER)青年药理学家奖(2018)

第三届刘昌孝院士人才奖:优秀青年科技工作者奖(2017)

第二十届中国药理学会青年药理学家(2016)

《药学学报》中英文两刊优秀青年编委(2020)

全国大学生生命科学创新创业大赛优秀指导教师一等奖 (2020)

国际药理学知名期刊Journal of Ethnopharmacology 杰出贡献奖(2018)

国际食品科学知名期刊Journal of Functional Foods 杰出贡献奖(2017)

国际药学知名期刊Journal of Pharmaceutical and Biomedical Analysis 杰出贡献奖(2017,2016,2015)

国际植物医学知名期刊Phytomedicine 杰出贡献奖(2016)

科研项目

主持国家自然科学基金(82274010)

主持国家自然科学基金(81773808)

主持国家自然科学基金(81301908)

主持上海市自然科学基金(13ZR1412600)

主持上海市科委实验动物创新基金(15140904700)

主持上海市科委“科技创新行动计划”实验动物研究领域重点项目17140901000

主持上海市科委“科技创新行动计划”科技合作项目(18430760400)

主持上海市长宁区卫生健康委员会科研项目(2019CNECNUPI02)

主持中央高校基本科研业务费专项资金项目(40500-20104-222370)

参与国家自然科学基金重点项目(81830083

参与上海市科委基金多项(11DZ2260300, 12XD1406100, 14DZ2270100

指导学生获奖

国家级

2023年 硕士生付田田 荣获研究生国家奖学金

2022年 硕士生徐媛 荣获研究生国家奖学金

2021年 硕士生刘洁 荣获国家研究生奖学金

2020年 徐媛,罗函荣获第五届全国大学生生命科学创新创业大赛一等奖

2019年 张远金荣获中国毒理学会药物毒理与安全性评价学术大会青年优秀论文奖

2019年 硕士生程怡,尚旭阳 获得国家研究生奖学金

2018年 覃璇 荣获博士研究生国家奖学金

2018年 张远金荣获第十二届全国药物和化学异物代谢大会青年优秀论文奖

2017年 硕士生唐朔文 获得国家研究生奖学金

2016年 博士生覃璇,陈昂 分别荣获第二届药物代谢朝阳论坛---朝阳学子报告二,三等奖

2016年 博士生鲁健获得中国药理学会第十四次全国学术大会优秀壁报奖

2016年 硕士生赵军芳 获得国家研究生奖学金

2015年 硕士生陈昂,覃璇 获得国家研究生奖学金

2014年 硕士生汤玉,丁同贵 获得国家研究生奖学金

2013年 硕士生孙敏 获得国家研究生奖学金

省级

2019年 梁辰美子 获上海市优秀毕业生称号

2019年 罗函,徐媛荣获上海大学生创新创业训练计划项目基金

2018年 鲁健荣获第五届浦江DMPK论坛优秀青年论文奖

2017年 赵军芳获上海市优秀毕业生称号

2015年 汤玉获上海市优秀毕业生称号

2014年 孙敏获上海市优秀毕业生称号

校级

2023年 徐媛荣获第32届十佳女大学生称号

2020年 尚旭阳,程怡 荣获华东师范大学优秀毕业生称号

2016年 张远金 获华东师范大学优秀毕业生称号

2016年 赵军芳 获华东师范大学优秀学生称号

2016年 硕士生周小静 获华东师范大学研究生科研创新基金

2015年 硕士生张远金 获华东师范大学优秀研究生奖学金

2015年 硕士生陈昂 获华东师范大学研究生科研创新基金

2014年 本科生张禾雨 获华东师范大学本科生优秀毕业论文



主编书籍

Xin Wang (Editor),《Dextromethorphan: Pharmacology, Clinical Uses and Health Effects》,ISBN:978-1-63484-016-3,美国诺华科学出版社Nova Science Publishers, Inc. (2015)


Xin Wang (Editor),《CRISPR: Advances in Research and Applications》,ISBN:978-1-53612-946-5,美国诺华科学出版社Nova Science Publishers, Inc. (2017)


参编书籍

1 《基础与临床中药毒理学》P377-386,香港商务出版社(2009)

2 《Caffeine Consumption and Health》P33-50,美国诺华科学出版社Nova Science Publishers, Inc. (2012)

3 《Advances in Chemistry Research: Volume 15》P133-142, 美国诺华科学出版社Nova Science Publishers, Inc. (2012)

4 《Cytochrome P450 Enzymes: Biochemistry, Pharmacology and Health Implications》P51-86, 美国诺华科学出版社Nova Science Publishers, Inc. (2014)


代表性论文

Zhang Y, Huang J, Huang S, Liu J, Deng L, Liang C, Guo Y, Yao B, Wang X*. Construction and characterization of a humanized SLCO1B1 rat model with its application in evaluating the uptake of different statins. Acta Pharmaceutica Sinica B 2024, 14(4): 1592-1604. (APSB推荐论文设计构建OATP1B1人源化大鼠模型用于研究他汀类药物的摄取转运


Liu J, Lu J, Yao B, Zhang Y, Huang S, Chen X, Shen Y, Wang X*. Construction of humanized CYP1A2 rats using CRISPR/Cas9 to promote drug metabolism and pharmacokinetic research. Drug Metabolism and Disposition 2024, 52(1): 56-62.  (Cover story)


Zhang Y, Yao B, Guo Y, Huang S, Liu J, Zhang Y, Liang C, Huang J, Tang Y, Wang X*. Sorafenib reduces the production of epoxyeicosatrienoic acids and leads to cardiac injury by inhibiting CYP2J in rats. Biochemical Pharmacology 2024, 223: 116169. doi: https://doi.org/10.1016/j.bcp.2024.116169



Shen Y, Liu J, Yao B, Zhang Y, Huang S, Liang C, Huang J, Tang Y, Wang X*Non-alcoholic fatty liver disease changes the expression and activity of hepatic drug-metabolizing enzymes and transporters in rats. Toxicology Letters 2024, 396: 36-47.

 


Chen X, Lu N, Huang S, Zhang Y, Liu Z, Wang X*Assessment of doxorubicin toxicity using human cardiac organoids: A novel model for evaluating drug cardiotoxicity.Chemico-Biological Interactions 2023, 386: 110777.


Lu J, Shang X, Yao B, Sun D, Liu J, Zhang Y, Wang H, Shi J, Chen H, Shi T, Liu M, Wang X*. The role of CYP1A1/2 in cholesterol ester accumulation provides a new perspective for the treatment of hypercholesterolemia. Acta Pharmaceutica Sinica B 2023, 13(2): 648-661. doi: 10.1016/j.apsb.2022.08.005


Zhang Y, Gao J, Xu Y, Liu J, Huang S, Li G, Yao B, Sun Z*, Wang X*. Investigation of cytochrome P450 inhibitory properties of deoxyshikonin, a bioactive compound from Lithospermum erythrorhizon Sieb. et Zucc. Phytotherapy Research 2023, doi: 10.1002/ptr.7664. 

Liu J, Shang X, Yao B, Zhang Y, Huang S, Guo YWang X*. Design and construction of carboxylesterase 2c gene knockout rats by CRISPR/Cas9. Current Drug Metabolism 2023, https://dx.doi.org/10.2174/1389200224666230123140919

Fu T, Yao B, Guo Y, Zhang Y, Huang S, Wang X*. Establishment of LC–MS/MS method for quantifying chlorpromazine metabolites with application to its metabolism in liver and placenta microsomes. Journal of Pharmaceutical and Biomedical Analysis 2023, 233: 115457.


Liao J, Chen S, Hsiao S, Jiang Y, Yang Y, Zhang Y, Wang X, Lai Y, Bauer DE, Wu Y. Therapeutic adenine base editing of human hematopoietic stem cells. Nature Communications 2023, 14(1): 207.

Zhang Y, Gao L, Yao B, Huang S, Zhang Y, Liu J, Liu Z*, Wang X*. Role of epoxyeicosatrienoic acids in cardiovascular diseases and cardiotoxicity of drugs. Life Sciences 2022, 310: 121122. doi: 10.1016/j.lfs.2022.121122


Liu J, Yao B, Gao L, Zhang Y, Huang S, Wang X*.  Emerging role of carboxylesterases in nonalcoholic fatty liver disease. Biochemical Pharmacology 2022, 205: 115250. 


Zhang Y, Zhang L, Xu P, Qin X, Wang P, Cheng Y, Yao B, Wang X*. Cytochrome P450 2E1 gene knockout or inhibition prevents obesity induced by high-fat diet via regulating energy expenditure. Biochemical Pharmacology 2022, 202: 115160.


Yu J, Chen X, Zhang Y, Cui X, Zhang Z, Guo W, Wang D, Huang S, Chen Y, Hu Y, Zhao C, Qiu J, Li Y, Meng M, Guo M, Shen F, Zhang M, Zhou B, Gu X, Wang J, Wang X*, Ma X*, Xu L*. Antibiotic Azithromycin inhibits brown/beige fat functionality and promotes obesity in human and rodents. Theranostics 2022; 12(3): 1187-1203. doi:10.7150/thno.63067


Xu Y, Lu J, Guo Y, Zhang Y, Liu J, Huang S, Zhang Y, Gao L*, Wang X*. Hypercholesterolemia reduces the expression and function of hepatic drug metabolizing enzymes and transporters in rats. Toxicology Letters 2022, 364: 1-11. doi.org/10.1016/j.toxlet.2022.05.009


Gao J, Zhang Y, Lei X, Xu Y, Sun Z*, Wang X*Risk assessment of the inhibition of hydroxygenkwanin on human and rat cytochrome P450 by cocktail method. Toxicol In Vitro 2022, 79: 105281. doi: 10.1016/j.tiv.2021.105281. 

Wang X, Fa J, Zhang Y, Huang S, Liu J, Gao J, Xing L, Liu Z*, Wang X*. Evaluation of herbdrug interaction between Danshen and rivaroxaban in rat and human liver microsomes. Frontiers in Pharmacology 2022, 13: 950525.

Lu J, Liu J, Guo Y, Zhang Y, Xu Y, Wang X*.  CRISPR-Cas9: A method for establishing rat models of drug metabolism and pharmacokinetics. Acta Pharmaceutica Sinica B 2021, 11(10): 2973-2982. doi.org/10.1016/j.apsb.2021.01.007


Liu J, Cheng Y, Zhang Y, Huang S, Liu Z*, Wang X*. Lactobacillus rhamnosus induces CYP3A and changes the pharmacokinetics of verapamil in rats. Toxicology Letters 2021, 352: 46-53. https://doi.org/10.1016/j.toxlet.2021.09.010 


Xu Y, Lu J, Yao B, Zhang Y, Huang S, Liu J, Zhang Y, Guo Y, Wang X*. P-glycoprotein mediates the pharmacokinetic interaction of olanzapine with fluoxetine in rats. Toxicology and Applied Pharmacology 2021, 431: 115735. https://doi.org/10.1016/j.taap.2021.115735


Liu J, Shang X, Huang S, Xu Y, Lu J, Zhang Y, Liu Z*, Wang X*. Construction and characterization of CRISPR/Cas9 knockout rat model of carboxylesterase 2a gene. Molecular Pharmacology 2021, 100: 480-490. (Editor Choice paper) DOI: https://doi.org/10.1124/molpharm.121.000357


Qin X, Zhang Y, Lu J, Huang S, Liu Z*, Wang X*. CYP3A deficiency alters bile acid homeostasis and leads to changes in hepatic susceptibility in rats. Toxicology and Applied Pharmacology 2021, 429: 115703. doi.org/10.1016/j.taap.2021.115703


Zhang Y, Huang S, Zhong W, Chen W, Yao B, Wang X*. 3D organoids derived from the small intestine: An emerging tool for drug transport research. Acta Pharmaceutica Sinica B 2021, 11(7): 1697-1707. doi.org/10.1016/j.apsb.2020.12.002


Sun D, Lu J, Zhang Y, Liu J, Liu Z, Yao B, Guo Y, Wang X*. Characterization of a novel CYP1A2 knockout rat model constructed by CRISPR/Cas9. Drug Metabolism and Disposition 2021, 49(8): 638-647.


Zhang Y, Huang S, Liu J, Wang X*. Construction and application of innovation gene-edited rats and intestinal 3D organoids models in drug metabolism and pharmacokinetics. Chinese Journal of Clinical Pharmacology and Therapeutics 2021, 26(8): 914-922. (Cover story)


Huang S, Zhang Y, Zhang Y, Liu J, Liu Z*, Wang X*. Establishment of LC-MS/MS method for determination of aloperine in rat plasma and its application in preclinical pharmacokinetics. Journal of Chromatography B 2021, 1173(2):122671. doi.org/10.1016/j.jchromb.2021.122671


Chen A, Zhang Y, Sun D,  Xu Y, Guo Y, Wang X*. Investigation of the content differences of arachidonic acid metabolites in a mouse model of breast cancer by using LC–MS/MS. Journal of Pharmaceutical and Biomedical Analysis 2021, 194: 113763.



Lu J, Chen A, Ma X, Shang X, Zhang Y, Guo Y, Liu M, Wang X*. Generation and Characterization of Cytochrome P450 2J3/10 CRISPR/Cas9 Knockout Rat Model. Drug Metabolism and Disposition 2020, 48(11): 1129-1136. (Cover Story)

About the cover: New CYP2J3/10 knockout rat model for drug metabolism and cardiovascular disease. See the article by Lu et al. (dx.doi.org/10.1124/dmd.120.000114).



Lu J, Shang X, Zhong W, Xu Y, Shi R, Wang X*. New insights of CYP1A in endogenous metabolism:a focus on single nucleotide polymorphisms and diseases. Acta Pharmaceutica Sinica B 2020, 10: 91-104. doi:10.1016/j.apsb.2019.11.016


Luo H, Xu Y, Sun D, Cheng Y, Sun Z, Gao J, Zhang Y, Wang X*. Assessment of the inhibition risk of paris saponins, bioactive compounds from Paris polyphylla, on CYP and UGT enzymes via cocktail inhibition assays. Regulatory Toxicology and Pharmacology 2020, 113: 104637. doi:10.1016/j.yrtph.2020.104637


Ma X, Shang X, Qin X, Lu J, Liu M, Wang X*. Characterization of organic anion transporting polypeptide 1b2 knockout rats generated by CRISPR/Cas9: A novel model for drug transport and hyperbilirubinemia disease.  Acta Pharmaceutica Sinica B 2020, 10: 850-860. doi:10.1016/j.apsb.2019.11.007


Li Y, Meng Q, Yang M, Liu D, Hou X, Tang L, Wang X#, Lyu Y, Chen X, Liu K, Yu A, Zuo Z, Bi H. Current Trends in Drug Metabolism and Pharmacokinetics. Acta Pharmaceutica Sinica B 2019, 9, 1113-1144. doi:10.1016/j.apsb.2019.10.001


Ma X, Qin X, Shang X, Liu M, Wang X*. Organic anion transport polypeptide 1b2 selectively affects the pharmacokinetic interaction between paclitaxel and sorafenib in rats. Biochemical Pharmacology 2019, 169: 113612doi:10.1016/j.bcp.2019.08.014


Qin X, Wang X*. Role of vitamin D receptor in the regulation of CYP3A gene expression. Acta Pharmaceutica Sinica B 2019, 9, 1087-1098. doi:10.1016/j.apsb.2019.03.005


Zhang L, Liang C, Xu P, Liu M, Xu F, Wang X*. Characterization of in vitro Mrp2 transporter model based on intestinal organoids. Regulatory Toxicology and Pharmacology 2019, 108: 104449. doi:10.1016/j.yrtph.2019.104449



Zhang L, Xu P, Cheng Y, Wang P, Ma X, Liu M, Wang X*, Xu F*. Diet-induced obese alters the expression and function of hepatic drug-metabolizing enzymes and transporters in rats. Biochemical Pharmacology 2019, 164, 368-376. doi:10.1016/j.bcp.2019.05.002


Liang C, Zhao J, Lu J, Zhang Y, Ma X, Shang X, Li Y, Ma X, Liu M, Wang X*. Development and characterization of MDR1 (Mdr1a/b) CRISPR/Cas9 knockout rat model. Drug Metabolism and Disposition 2019 Feb;47(2):71-79. doi: 10.1124/dmd.118.084277. Epub 2018 Nov 26


Cheng Y, Tang S, Chen A, Zhang Y, Liu M, Wang X*. Evaluation of the inhibition risk of shikonin on human and rat UDP-glucuronosyltransferases (UGT) through the cocktail approach. Toxicology Letters 2019, 312, 214-221. doi: 10.1016/j.toxlet.2019.05.017


Tang S, Ma X, Lu J, Zhang Y, Liu M, Wang X*. Preclinical toxicology and toxicokinetic evaluation of ailanthone, a natural product against castration-resistant prostate cancer, in mice. Fitoterapia 2019,136: 104161.doi:10.1016/j.fitote.2019.04.016


He Y, Peng S, Wang J, Chen H, Cong X, Chen A, Hu M, Qin M, Wu H, Gao S, Wang L, Wang X*, Yi Z*, Liu M*. Ailanthone targets p23 to overcome MDV3100 resistance in castration-resistant prostate cancer. Nature Communications 2016, 7:13122.

Cancer: Antimalarial agent shows potential for prostate cancer treatment(Nature Communications)

A drug used for malaria could stop prostate cancer tumours growing

Prostate cancer NEWS: Deadly tumours could be treated with MALARIA drug


Wang P, Qin X, Liu M, Wang X*.The burgeoning role of cytochrome P450-mediated vitamin D metabolites against colorectal cancer. Pharmacological Research 2018, 133, 9-20. doi:10.1016/j.phrs.2018.04.022


Qin X, Wang X*Quantification of nucleotides and their sugar conjugates in biological samples: Purposes, instruments and applications. Journal of Pharmaceutical and Biomedical Analysis 2018, 158, 280-287. doi:10.1016/j.jpba.2018.06.013 (The invited review)


Lu J, Liu D, Zhou X, Chen A, Jiang Z, Ye X, Liu M, Wang X*.Plant natural product plumbagin presents potent inhibitory effect on human cytochrome P450 2J2 enzyme. Phytomedicine 2018, 39, 137-145. doi: 10.1016/j.phymed.2017.12.026


Chen A, Zhou X, Cheng Y, Tang S, Liu M, Wang X*Design and optimization of thecocktail assay for rapid assessment of the activity of UGT enzymes in human and rat liver microsomes. Toxicology Letters 2018, 295, 379-389. doi: 10.1016/j.toxlet.2018.07.021


Li J, Li L, Qin X, Degrace P,  Demizieux L, Limbu S, Wang X, Zhang M, Li D, Du Z. Inhibited carnitine synthesis causes systemic alteration of nutrient metabolism in zebrafish. Frontiers in Physiology2018, 9, 509. doi:10.3389/fphys.2018.00509


Su L, Li J, Zhou Z, Huang D, Zhang Y, Pei H, Guo W, Wu H, Wang X, Liu M, Yang CG, Chen Y. Design, synthesis and evaluation of hybrid of tetrahydrocarbazole with 2,4-diaminopyrimidine scaffold as antibacterial agents. European Journal of Medicinal Chemistry 2018 Nov 8;162:203-211. doi: 10.1016/j.ejmech.2018.11.016. 


Zhang L, Zhao J, Liang C, Liu M, Xu F*Wang X*A novel biosensor based on intestinal 3D organoids for detecting the function of BCRP. Drug Delivery 2017, 24, 1453-1459. doi:10.1080/10717544.2017.1381199


Tang S, Chen A, Zhou X, Zeng L, Liu M, Wang X*. Assessment of the inhibition risk of shikonin on cytochrome P450 via cocktail inhibition assay. Toxicology Letters 2017, 281, 74-83. doi: 10.1016/j.toxlet.2017.09.014


Qin X, Lu J, Wang P, Xu P, Liu M, Wang X*Cytochrome P450 3A selectively affects the pharmacokinetic interaction between erlotinib and docetaxel in rats. Biochemical Pharmacology 2017, 143,129-139. doi:10.1016/j.bcp.2017.07.013


Lu J, Zhang Y, Sun M, Liu M, Wang X*. Comprehensive assessment of Cucurbitacin E related hepatotoxicity and drug-drug interactions involving CYP3A and P-glycoprotein. Phytomedicine 2017, 26, 1-10.



Lu J, Shao Y, Qin X, Liu D, Chen A, Li D*, Liu M*Wang X*. CRISPR knockout rat cytochrome P450 3A1/2 model for advancing drug metabolism and pharmacokinetics research. Scientific Reports 2017, 7,42922.



Li JM, Li LY, Qin X, Ning LJ, Lu DL, Li DL, Zhang ML, Wang X*, Du ZY*. Systemic regulation of L-carnitine in nutritional metabolism in zebrafish, Danio rerio. Scientific Reports 2017, 7, 40815.


Qin X, Chen A, Lu J, Zhang YJ, Liu MY, Wang X*. Evaluation of plasma stability and pharmacokinetics of parthenolide in rats with LC-MS/MS analysis. Acta Pharmaceutica Sinica 2017, 52, 609-614. doi:10.16438/j.0513-4870.2016-1006


Wang X*, Tang Y, Lu J, Shao Y, Qin X, Li Y, Wang L, Li D, Liu M. Characterization of novel cytochrome P450 2E1 knockout rat model generated by CRISPR/Cas9. Biochemical Pharmacology 2016, 105, 80-90.


Qin X, Liu M, Wang X*. New insights into the androgen biotransformation in prostate cancer: a regulatory network among androgen, androgen receptors and UGTs .Pharmacological Research 2016, 106, 114-22.


Zhao J, Zeng Z, Sun J, Zhang Y, Li D, Zhang X, Liu M, Wang X*. A Novel Model of P-Glycoprotein Inhibitor Screening Using Human Small Intestinal Organoids. Basic & Clinical Pharmacology & Toxicology 2017, 120, 250-255.


Chen A, Zhou X, Tang S, Liu M, Wang X*. Evaluation of the inhibition potential of plumbagin against cytochrome P450 using LC-MS/MS and cocktail approach. Scientific Reports 2016, 6, 28482.


Zhang Y, Zeng Z, Zhao J, Li D, Liu M, Wang X*Measurement of Rhodamine 123 in Three-Dimensional Organoids: A Novel Model for P-Glycoprotein Inhibitor Screening. Basic & Clinical Pharmacology & Toxicology 2016, 119, 349-352.


Qin M, Peng S, Liu N, Hu M, He Y, Li G, Chen H, He Y, Chen A, Wang X, Liu M, Chen Y, Yi Z. LG308, a novel synthetic compound with anti-microtubule activity in prostate cancer cells, exerts effective antitumor activity. J Pharmacol Exp Ther.2015, 355, 473-483. 


Lu J, Ding T, Qin X, Liu M, Wang X*. In vitro and in vivo evaluation of cucurbitacin E on rat hepatic CYP2C11 expression and activity using LC-MS/MS. Sci China Life Sci. 2017,60, 215-224. doi10.1007/s11427-015-4911-7. 


Zheng C, Zhou W, Wang T, You P, Zhao Y, Yang Y, Wang X, Luo J, Chen Y, Liu M, Chen H. A Novel TGR5 Activator WB403 Promotes GLP-1 Secretion and Preserves Pancreatic β-Cells in Type 2 Diabetic Mice. PLoS One 2015 Jul 24;10(7):e0134051. doi: 10.1371/journal.pone.0134051.


Chen A, Qin X, Lu J, Yi Z, Liu M, Wang X*. Development of a validated LC-MS/MS method for the determination of ailanthone in rat plasma with application to pharmacokinetic study. Journal of Pharmaceutical and Biomedical Analysis 2015, 102, 514-518.


Sun M, Tang Y, Ding T, Liu M,Wang X*. Investigation of cytochrome P450 inhibitory properties of maslinic acid, a bioactive compound from Olea europaea L., and its structure-activity relationship. Phytomedicine 2015, 22, 56-65.


Ding T, Zhang Y, Chen A, Tang Y, Liu M, Wang X*(Corresponding author). Effects of Cucurbitacin E, a Tetracyclic Triterpene Compound from Cucurbitaceae, on the Pharmacokinetics and Pharmacodynamics of Warfarin in Rats. Basic & Clinical Pharmacology & Toxicology 2015, 116, 385-389. DOI: 10.1111/bcpt.12329


Yang F, Zhang T, Wu H, Yang Y, Liu N, Chen A, Li Q, Li J, Qin L, Jiang B, Wang X, Pang X, Yi Z, Liu M, Chen Y. Design and Optimization of Novel Hydroxamate-Based Histone Deacetylase Inhibitors of Bis-Substituted Aromatic Amides Bearing Potent Activities against Tumor Growth and Metastasis. Journal of Medicinal Chemistry 2014, 57, 9357-9369. DOI: 10.1021/jm5012148


Chen A, Qin X, Tang Y, Liu M, Wang X*. Evaluation of enzyme inhibition kinetics in drug-drug interactions. Chemico-Biological Interactions 2014, 222, 133-134.


Lu J, Qin X, Liu M, Wang X*. A note on CYP2J2-mediated terfenadine hydroxylation in human liver microsomes. Food and Chemical Toxicology 2014, 71, 284-285.


Sun M, Tang Y, Ding T, Liu M, Wang X*. Inhibitory effects of celastrol on rat liver cytochrome P450 1A2, 2C11, 2D6, 2E1 and 3A2 activity. Fitoterapia 2014, 92, 1-8.