Main funding support

1. National Natural Science Foundation of China Youth Fund (82304428), from January 2024 to December 2026.12, with a total of 300000 yuan, presided over;

2. Jiangsu Provincial Natural Science Foundation Youth Fund (BK20221042), July 2022-20225.07, 200000 yuan, presided over;

3. Chen'an Biotechnology's "Qingyun Plan" (only ten projects nationwide), with a sample testing fee of 500000 yuan, from January 2022 to May 2021, hosted by;

4. The research start-up fund of China Pharmaceutical University ranges from September 2021 to September 2027-091 million, with the principal investigator.

5. China Pharmaceutical University Youth Talent Cross Project, with 2023.07-202.5073 million participants.

Representative papers

1.Wenguang Wang#,  Haiheng Xu#, Qingsong Ye#, Feng Tao, Ian Wheeldon, Ahu Yuan, Yiqiao Hu*, Jinhui Wu*, Systemic immune responses to irradiated tumours via the transport of antigens to the tumour periphery by injected flagellate bacteria., Nature Biomedical Engineering. 2022.

2.Wenguang Wang#,  Yuhao Cheng#, Peng Yu#, Haoran Wang, Yue Zhang, Haiheng Xu, Qingsong Ye, Ahu Yuan*, Yiqiao Hu*, Jinhui Wu*, Perfluorocarbon regulates the intratumoural environment to enhance hypoxia-based agent efficacy. Nature Communications. 2019, 10:1580.

3.Shuqian Ma#, Kaiyuan Hu#, Junjie Xue#, Di Wu, Ya Chu, Fangfei Jin, Weijun Zhao, Yiqiao Hu, Jing Yan*, Jinhui Wu*, Yong Yang*, Wenguang Wang*. Self-assembly nanoparticles potentiate in-situ tumor vaccine of radiotherapy by regulating tumor immunogenicity and tumor-associated macrophages. Chemical Engineering Journal (2024): 154663.

4.Wenguang Wang#,*, Xingli Wang#, Feng Tao, Kaiyuan Hu, Junying Zhang, Jinhui Wu,Linjun You*, Weijun Zhao*, Fluorinated hyaluronic acid encapsulated perfluorocarbon nanoparticles as tumor-targeted oxygen carriers to enhance radiotherapy. Molecular Pharmaceutics.19.11 (2022): 3948-3958.

5.Wentao Song, Yiming Wang, Bing Wang, Yingfang Yao, Wenguang Wang, Jinhui Wu, Qing Shen, Wenjun Luo, Zhigang Zou. (2020).  Super stable CsPbBr3@ SiO2 tumor imaging reagent by stress-response encapsulation. Nano Research, 13(3), 795-801.

Representative patents:

1. Wang Wenguang, Yang Yong, Zuo Shuguang, Zhao Lili, Chu Ya, Lv Miao, Wang Luyao, Lin Ang, Zhao Weijun. A tumor neoantigen vaccine system with specific labeling of heterologous proteins and its application (CN202311338909.3).

2. Yang Yong, Wang Wenguang, Li Xianjing, Chen Yiwei, Xue Junjie, Du Xiuli, Lin Ang, Zhao Weijun. A targeted mRNA-LNP delivery system, preparation method, and application for in vivo CAR-M cell therapy (CN202410220054.2).

3. Wu Jinhui, Wang Wenguang, Tao Feng, Xu Haiheng, Hu Yiqiao. A modified bacterium and its preparation method and application (CN202210061247.9).