成果及论文 - 中国药科大学王文广组

主要基金资助

1. 国家自然科学基金青年基金(82304428)，2024.01-2026.12，30万，主持；

2. 江苏省自然科学基金青年基金 (BK20221042)，2022.07-2025.07，20万，主持；

3. 宸安生物 “青云计划”（全国仅十项），50万样本检测费，2022.01-2025.01，主持；

4. 中国药科大学科研启动经费,2021.09-2027-09，100万，主持。

5. 中国药科大学青年人才交叉项目，2023.07-2025.07，300万，参与。

代表性论文

1.Wenguang Wang^#, Haiheng Xu^#, Qingsong Ye^#, Feng Tao, Ian Wheeldon, Ahu Yuan, Yiqiao Hu*, Jinhui Wu*, Systemic immune responses to irradiated tumours via the transport of antigens to the tumour periphery by injected flagellate bacteria., Nature Biomedical Engineering. 2022.https://www.nature.com/articles/s41551-021-00834-6

2.Wenguang Wang^#, Yuhao Cheng^#, Peng Yu^#, Haoran Wang, Yue Zhang, Haiheng Xu, Qingsong Ye, Ahu Yuan*, Yiqiao Hu*, Jinhui Wu*, Perfluorocarbon regulates the intratumoural environment to enhance hypoxia-based agent efficacy. Nature Communications. 2019, 10:1580.https://www.nature.com/articles/s41467-019-09389-2

3.Shuqian Ma^#, Kaiyuan Hu^#, Junjie Xue^#, Di Wu, Ya Chu, Fangfei Jin, Weijun Zhao, Yiqiao Hu, Jing Yan*, Jinhui Wu*, Yong Yang*, Wenguang Wang*. Self-assembly nanoparticles potentiate in-situ tumor vaccine of radiotherapy by regulating tumor immunogenicity and tumor-associated macrophages. Chemical Engineering Journal (2024): 154663.https://www.sciencedirect.com/science/article/abs/pii/S1385894724061540

4.Wenguang Wang^#,*, Xingli Wang^#, Feng Tao, Kaiyuan Hu, Junying Zhang, Jinhui Wu,Linjun You*, Weijun Zhao*, Fluorinated hyaluronic acid encapsulated perfluorocarbon nanoparticles as tumor-targeted oxygen carriers to enhance radiotherapy. Molecular Pharmaceutics.19.11 (2022): 3948-3958.https://pubs.acs.org/doi/abs/10.1021/acs.molpharmaceut.2c00432

5.Wentao Song, Yiming Wang, Bing Wang, Yingfang Yao, Wenguang Wang, Jinhui Wu, Qing Shen, Wenjun Luo, Zhigang Zou. (2020). Super stable CsPbBr3@ SiO2 tumor imaging reagent by stress-response encapsulation. Nano Research, 13(3), 795-801.https://link.springer.com/article/10.1007/s12274-020-2697-9

代表性专利：

1. 王文广，杨勇，左曙光，赵莉莉，褚亚，吕淼，王璐瑶，林昂，赵维俊。一种特异性标记异源蛋白的肿瘤新抗原疫苗体系及其应用（CN202311338909.3）。

2. 杨勇，王文广，李娴静，陈一为，薛俊杰，杜秀丽，林昂，赵维俊。一种在体构建CAR-M细胞疗法的靶向性mRNA-LNP递送系统及制法和应用（CN202410220054.2）。