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成果及论文

  1. Shoucheng Wang, Yongjie Chi, Danyang Wang, Kai Zhao*, Lianyan Wang*, Regulation of Oxygen in the Tumor Microenvironment Synergizes with Immunotherapy to Suppress Tumor Progression, Journal of Functional Biomaterials, 2024, 15:357. (IF: 5.0)

  2. Yuan Gao, Shulan Han, Funa Lu, Qi Liu, Jun Yang, Wenling Wang, Yuanyuan Wang, Jing Zhang,Ruijun Ju, Xiaoling Shen, Yanping Zhao*, Hongjun Wang*, Wenjie Tan*, and Lianyan Wang*; Dimethyl-Dioctadecyl-Ammonium Bromide/Poly(lactic acid) Nano-Adjuvant Enhances the Immunity and Cross-Protection of NM2e-Based Universal Influenza Vaccine, ACS Nano, 2024, 18, 20, 12905-12916.(IF: 15.8)

  3. Pengwei Xu, Xiaojie Yue, Xiaofan Yuan*, Bing Zhao*, Hemp seed globulin-alginate nanoparticles for encapsulation of Cannabisin A with enhanced colloidal stability and antioxidant activity，International Journal of Biological Macromolecules, 2024,256 :128380. (IF: 8.2)

  4. Pengwei Xu, Xiaojie Yue, Xiaofan Yuan*, Bing Zhao*, Non-covalent interaction between hemp seed globulin and two hemp seed phenolic compounds: Mechanism and effects on protein structure, bioactivity, and in vitro simulated digestion，International Journal of Biological Macromolecules，2024, 255:128077. (IF: 8.2)

  5. Pengwei Xu, Xiaofan Yuan*, Bing Zhao*. Jet milling improves the polyphenol dissolution profile and biological activitiesof the hemp seed shell. Food Bioscience, 2024, 57:103497. (IF: 4.8)

  6. Yuan Gao, Jun Yang, Yaru Zhang, Ying Zhao, Xin Zhao, Xining Zhang, Jing Zhang, Li Mao*, Hongjun Wang*, Huimei Wang*, Lianyan Wang*, In vitro and in vivo evaluation of immune response of poly(lactic acid) nanoparticles with different end groups, International Journal of Biological Macromolecules, 2023, 253: 126593. (IF: 8.2)

  7. Shulan Han, Yongjie Chi, Zhu Yang, Juan Ma and Lianyan Wang*,umor Microenvironment Regulation and Cancer Targeting Therapy Based on Nanoparticles, Journal of Functional Biomaterials, 2023, 14: 136. (IF: 5.0)

  8. Pengwei Xu, Xiaofan Yuan*, Bing Zhao*, Bioactive polyphenols separated from hemp seed shells ameliorate H2O2-induced oxidative stress injury in human umbilical vein endothelial cells. Journal of Food Science, 2023, 88:537–551.(IF: 3.2)

  9. Yuan Zhu, Hang Li, Pengwei Xu, Xiaofan Yuan* and Bing Zhao*, Natural deep eutectic solvent extraction of chlorogenic acid from Eucommia leaves: high extractability, stability, antibacterial, and antioxidant activity, New Journal of Chem, 2023, 47:18096-18107. (IF: 2.7)

  10. Pengwei Xu, Xiaofan Yuan*, Bing Zhao*,  Covalent modification of hemp seed polyphenols improves the structural and functional properties of the main hemp seed protein fraction，Food Bioscience，2023, 56:103293. (IF: 4.8)

  11. Pengwei Xu, Xiaofan Yuan*, Bing Zhao*, A study on pH-mediated variations and differences in the structure and function of hemp seed albumin, globulin, and protein isolate. Food Bioscience, 2023, 56:103452.(IF: 4.8)

  12. Pengwei Xu, Xiaofan Yuan*, Bing Zhao*, Preparation, characterization, and physicochemical property of the inclusion complexes of Cannabisin A with ,B-cyclodextrin and hydroxypropyl- B-cyclodextrin. Journal of Molecular Structure, 2023, 1272-1282. (IF: 4.0)

  13. Yuan Gao, Siru Guo, Ying Zhao, Qianru Ji, Cholil Yun, Shengfang Wang, Yaru Zhang, Wenjie Wang, Huimei Wang. Extraction and preconcentration of the main target polyphenols from Empetrum nigrum by freeze-ultrasonic thawing method based on synthetic gemini surfactant aqueous systems. Food and Bioprocess Technology, 16 (2023) 844-856. (IF: 5.6）

  14. Yuan Gao, Yutong Shi, Na Miao, Wenxin Xing, Cholil Yun, Shengfang Wang, Wenjie Wang, Huimei Wang. A green ultrasound-assisted enzymatic extraction method for efficient extraction of total polyphenols from Empetrum nigrum and determination of its bioactivities. Journal of Industrial and Engineering Chemistry, 109 (2022) 559-567. (IF: 6.1)

  15. Yuan Gao, Quanxing Dong, Shuting Zhao, Ying Zhao, Yaru Zhang, Hailong Wang, Yajun Wang, Wenjie Wang, Lianyan Wang*, Huimei Wang*. Efficient ultrasound-assisted enzymatic method for extraction of immunostimulant QS-21 from Quillaja Saponaria Molina. Industrial Crops & Products, 2022, 189: 115807.（IF: 5.6）

  16. Xin Zhao, Lianyan Wang, Yanhua Zhu*. Development of COVID-19 Recombinant Subunit Vaccine and Adjuvant. Frontiers in Medical Science Research, 2022, 4(12): 35-40.

  17. Zhu Yang, Yongjie Chi, Jiaxin Bao, Xin Zhao, Jing Zhang and Lianyan Wang*. Virus-like Particles for TEM Regulation and Antitumor Therapy. Journal of Functional Biomaterials, 2022, 13: 304.（IF: 5.0）

  18. Yongjie Chi, Peng Sun, Yuan Gao, Jing Zhang and Lianyan Wang*. Ion Interference Therapy of Tumors Based on Inorganic Nanoparticles. Biosensor, 2022, 12: 100.（IF: 4.9）

  19. Cholil Yun, Shengfang Wang, Yuan Gao, Na Miao, Yutong Shi, Ilbong Ri, Wenjie Wang, Huimei Wang. Optimization of ultrasound-assisted enzymatic pretreatment for enhanced extraction of baicalein and wogonin from Scutellaria baicalensis. Journal of Chromatography B, 1188 (2022) 123077. (IF: 3.0) 

  20. Na Miao, Cholil Yun, Yutong Shi, Yuan Gao, Shuang Wu, Zhonghua Zhang, Shulan Han, Huimei Wang, Wenjie Wang. Enhancement of flavonoid synthesis and antioxidant activity in Scutellaria baicalensis aerial parts by UV-A radiation. Industrial Crops and Products, 187 (2022) 115532. (IF:5.9)

  21. Na Miao, Cholil Yun, Shulan Han, Yutong Shi, Yuan Gao, Shuang Wu, Zhuowen Zhao, Huimei Wang, Wenjie Wang. Postharvest UV-A radiation affects flavonoid content, composition, and bioactivity of Scutellaria baicalensis root. Postharvest Biology and Technology, 189(2022)111933. (IF: 7.0)

  22. Cholil Yun, Xiaochao Ji, Yuwen Chen, Zhuowen Zhao, Yuan Gao, Lin Gu, Danqi She, Ilbong Ri, Wenjie Wang, Huimei Wang. Ultrasound-assisted enzymatic extraction of Scutellaria baicalensis root polysaccharide and its hypoglycemic and immunomodulatory activities. International Journal of Biological Macromolecules, 227 (2022)134-145. (IF: 8.2)

  23. Cholil Yun, Zhuowen Zha, Ilbong Ri, Yuan Gao, Yutong Shi, Na Miao, Lin Gu, Wenjie Wang, Huimei Wang. How does UV-B stress affect secondary metabolites of Scutellaria baicalensis in vitro shoots grown at different 6-benzyl aminopurine concentrations? Physiologia Plantarum, 2022;174:e13778. (IF: 6.4)

  24. Yuan Gao, Shengfang Wang, Shikun Dang, Shulan Han, Cholil Yun, Wenjie Wang, Huimei Wang. Optimized ultrasoud-assisted extraction of total polyphenols from Empetrum nigrum and its bioactivities. Journal of Chromatography B, 1173 (2021) 122699. (IF: 3.0)

  25. Shulan Han†, Wenyan Ma†, Dawei Jiang†, Logan Sutherlin, Jing Zhang, Yu Lu, Nan Huo, Zhao Chen, Jonathan W. Engle, Yanping Wang*, Xiaojie Xu*, Lei Kang*, Weibo Cai* and Lianyan Wang*. Intracellular signaling pathway in dendritic cells and antigen transport pathway in vivo mediated by an OVA@DDAB/PLGA nano‑vaccine. Journal of Nanobiotechnology, 2021, 19:394-425. (IF: 10.6)

  26. Lingzhi Zhang, Mingyan Li, Changxing Gao, Shengfang Wang, Lianyan Wang*, Qing Zhu*. Micro- and nano-encapsulated hybrid system (MNEHDS): a novel approach for colon-targeted oral delivery of berberine. Molecular Pharmaceutics, 2021, 18: 1573-1581. (IF: 4.5)

  27. Shulan Han, Wenjie Wang, Shengfang Wang, Tingyuan Yang, Guifeng Zhang, Di Wang, Ruijun Ju, Yu Lu, Huimei Wang*, Lianyan Wang*. Tumor microenvironment remodeling and tumor therapy based on M2-like tumor associated macrophage-targeting nano-complexes. Theranostics, 2021,11(6): 2892-2916. (IF: 12.4)

  28. Lu Xu, Chun Zhang, Jing Zhang, Rong Yu, Zhiguo Su. Design, Synthesis and Primary Immunologic Evaluation of M2e-CRM197 Conjugate as a Universal Influenza Vaccine Candidate. Curr Pharm Biotechnol, 2021,22 (14):1910-1918. (IF: 2.2)

  29. Shulan Han, Wenjie Wang, Shengfang Wang, Shuo Wang, Ruijun Ju, Zihao Pan, Tingyuan Yang, Guifeng Zhang, Huimei Wang(*) and Lianyan Wang*. Multifunctional biomimetic nanoparticles loading baicalin for polarizing tumor-associated macrophages. Nanoscale, 2019, 11 (42): 20206-20220. (IF: 5.8)

  30. Qi Liu, Xiaoming Chen, JileiJia, Ting Lu, Tingyuan Yang, Lianyan Wang*, Potential Hepatitis B Vaccine Formulation Prepared by Uniform-Sized Lipid Hybrid PLA Microparticles with Adsorbed Hepatitis B Surface Antigen, Mol. Pharmaceutics, 2018, 15 (11): 5227-5235 . (IF: 4.9)

  31. ChengchengJia, Tingyuan Yang, Yongjiang Liu, Ali Zhu, Fei Yin, Yajun Wang, Lan Xu, Yan Wang, Mei Yan, Qingman Cai, Xiaoxu Liang, Ruijun Ju,,Jianping Chen*, Lianyan Wang*, A Novel Human papillomavirus 16 L1 Pentamer-loaded Hybrid Particles Vaccine System: Influence of size on Immune Responses, ACS Appl. Mater. Inter., 2018, 10(42): 35745-35759. (IF: 8.3) 

  32. Meiyang Yang, Tingyuan Yang, ,JileiJia, Ting Lu, Hailin Wang, Xueying Yan(*), Lianyan Wang(*), Lian Yuand Yue Zhao, Fabrication and characterization of DDAB/PLA-alginate composite microcapsules as single-shot vaccine, RSC Adv., 2018, 8: 13612-13624. (IF: 3.9)

  33. Huimei Wang, Shulan Han, Lianyan Wang∗, Tingyuan Yang, Guifeng Zhang, Lian Yu, Yue Zhao, Dual-function baicalin and baicalin-loaded poly(lactic-co-glycolicacid) nanoparticles: Immune activation of dendritic cells and arrest of the melanoma cell cycle at the G2/M phase, Particuology, 2018, 37: 64-71.(IF: 4.1)

  34. LianyanWang(*), Qi Liu, JileiJia, Tingyuan Yang, Guanghui Ma, Design of pH-responsive poly(D, L-lactic-co-glycolic acid) nanoparticles to promote immune response, J Control Release, 2017, 259: E81. (IF: 10.5)

  35. Xing Wang, Xia Wu, Helin Xing, Guilan Zhang, Quan Shi, Lingling E, Na Liu, Tingyuan Yang, Dongsheng Wang, Feng Qi, Lianyan Wang(*), Hongchen Liu(*), Porous Nanohydroxyapatite/Collagen Scaffolds Loading Insulin PLGA Particles for Restoration of Critical Size Bone Defect, ACS Appl. Mater. Inter., 2017, 9(13): 11380-11391. (IF: 8.3) 

  36. Jilei Jia, Qi Liu, Tingyuan Yang, LianyanWang(*), and Guanghui Ma(*), Facile Fabrication of Varisized Calcium Carbonate Microspheres as Vaccine Adjuvant, J. Mater. Chem. B, 2017, 5(8): 1611-1623. (IF: 6.1)

  37. Jilei Jia, Weifeng Zhang, Qi Liu, Tingyuan Yang, Lianyan Wang(*), Guanghui Ma(*), Adjuvanticity Regulation by Biodegradable Polymeric Nano-/microparticles Size, Mol. Pharmaceutics, 2017, 14(1): 14–22. (IF: 4.9)

  38. Qi Liu, JileiJia, Tingyuan Yang, Qingze Fan, Lianyan Wang(*), and Guanghui Ma(*), Pathogen-Mimicking Polymeric Nanoparticles Based on Dopamine Polymerization as Vaccines Adjuvants Induce Robust Humoral and Cellular Immune Responses, Small, 2016, 12 (13): 1744-1757. (IF: 13)

  39. Zhan Zhou, Jing Zhang, Yan Zhang, Guanghui Ma, Zhiguo Su. Specific Conjugation of the Hinge Region for Homogeneous Preparation of Antibody Fragment-Drug Conjugate: A Case Study for Doxorubicin-PEG-anti-CD20 Fab' Synthesis. Bioconjug Chem. 2016, 27(1):238-46. (IF: 4.0)

  40. Hui Liu, Lianyan Wang, Tingyuan Yang, Guifeng Zhang, Jian Huang, Jing Sun, Junsheng Huo, Optimization and Evaluation of fish oil microcapsules, Particuology, 2016, 29: 162-168. (IF: 4.1)

  41. Bo Zhang, Tingyuan Yang, Qibao Wang(*), Guifeng Zhang, JunshengHuo, Jian Huang, and Lianyan Wang(*), Fabrication of uniform alginate-agarose microcapsules loading FeSO4 using water-oil-water-oil multiple emulsions system combined with premix membrane emulsification technique, Colloids and Surfaces A: Physicochemical and Engineering Aspects, 2016, 498: 128-138. (IF: 4.9)

  42. Qi Liu, Xiaoming Chen, JileiJia, Weifeng Zhang, Tingyuan Yang, Lianyan Wang(*), and Guanghui Ma(*), pH-Responsive Poly(D,L‑lactic-co-glycolicacid) Nanoparticles with Rapid Antigen Release Behavior Promote Immune Response, ACS Nano, 2015, 9 (5) : 4925-4938. (IF: 15.8)

  43. Tingyuan Yang(*), Tongtong Ma, Lianyan Wang, Dong Wang, and Guanghui Ma(*), Uniform-sized PLGA-HSPC lipospheres as a biocompatible platform for controlled release of proteins and peptides, J Control Release, 2015, 213: E105-E106. (IF: 10.5)

  44. Weifeng Zhang(*), Lianyan Wang, Yuan Liu, Xiaoming Chen, Qi Liu, JileiJia, and Guanghui Ma(*), Regulating the surface charges of polymeric microparticles to improve the efficacy of particle-adjuvanted vaccine, J Control Release, 2015, 213: E105-E106. (IF: 10.5)

  45. Weifeng Zhang(#), Lianyan Wang(#), Tingyuan Yang, Yuan Liu, Xiaoming Chen, Qi Liu, JileiJia, and Guanghui Ma(*), Immunopotentiator-loaded polymeric microparticles as robust adjuvant to improve vaccine efficacy, Pharm Res, 2015, 32(9): 2837-2850. (IF: 3.5)

  46. Lianyan Wang(#), Tingyuan Yang(#), and Guanghui Ma(*), Particle Design of Membrane Emulsification for Protein Drug and Vaccine Delivery, Curr Pharm Design, 2015, 21 (19) : 2563-2598. (IF: 2.6)

  47. Lianyan Wang(*), MingmingCai, Yuan Liu, Tingyuan Yang, Yejing Zeng, Yueling Zhang, Qiang Li, Baocheng Zhu, and Guanghui Ma(*), Polymer hydrophobicity regulates paclitaxel distribution in microspheres, release profile and cytotoxicity in vitro, Powder Technol, 2015, 275 : 77-84. (IF: 4.5)

  48. Weifeng Zhang(#), Lianyan Wang(#), Yuan Liu, Xiaoming Chen, Qi Liu, JileiJia, Tingyuan Yang, ShaohuiQiu, and Guanghui Ma(*), Immune responses to vaccines involving a combined antigen-nanoparticle mixture and nanoparticle-encapsulated antigen formulation, Biomaterials, 2014, 35(23): 6086-6097. (IF: 12.8)

  49. Xiaoming Chen, Yuying Liu, Lianyan Wang(*), Yuan Liu, Weifeng Zhang, Bei Fan, Xiaowei Ma, Qipeng Yuan, Guanghui Ma(*), and Zhiguo Su(*), Enhanced humoral and cell-mediated immune responses generated by cationic polymer coated PLA microspheres with adsorbed HBsAg, Mol Pharmaceuts, 2014, 11(6): 1772-1784. (IF: 4.5)

  50. Lin Dai, Tingyuan Yang, Jing He, Lihong Deng, Jing Liu, Luying Wang, Jiandu Lei(*), and Lianyan Wang(*), Cellulose-graft-poly(L-lactic acid) nanoparticles for efficient delivery of anti-cancer drugs, J Mater Chem B, 2014, 2: 6749-6757. (IF: 6.1)

  51. Weifeng Zhang(#), Lianyan Wang(#), Yuan Liu, Xiaoming Chen, Jiahui Li, Tingyuan Yang, Wenqi An, Xiaowei Ma, Ruowen Pan, and Guanghui Ma(*), Comparison of PLA Microparticles and Alum as Adjuvants for H5N1 Influenza Split Vaccine: Adjuvanticity Evaluation and Preliminary Action Mode Analysis, Pharm Res, 2014, 31(4): 1015-1031. (IF: 3.5)

  52. Tongtong Ma(#), Lianyan Wang(#), Tingyuan Yang, Dong Wang , Guanghui Ma(*), and Siling Wang(*), PLGA-lipid liposphere as a promising platform for oral delivery of proteins, Colloid Surface B, 2014, 117: 512-519. (IF: 5.4)

  53. Tongtong Ma(#), Lianyan Wang(#), Tingyuan Yang, Dong Wang , Guanghui Ma(*), and Siling Wang(*), M-cell targeted polymeric lipid nanoparticles containing a toll-like receptor agonist to boost oral immunity, Int J Pharm., 2014, 473(1-2): 296-303. (IF: 5.3)

  54. Yuan Liu, Yu Zhang, Xiaoxiao Yang, Lianyan Wang(*), and Guanghui Ma(*), Uniform-sized water-in-oil vaccine formulations enhance immune response against Newcastle disease and avian influenza in chickens, Int Immunopharm, 2014, 23(2): 603-608. (IF: 4.8)

  55. Xiaoming Chen, LianyanWang(*), Qi Liu, JileiJia, Yuan Liu, Weifeng Zhang, Guanghui Ma(*), and Zhiguo Su(*). Polycation-decorated PLA microspheres induce robust immune responses via commonly used parenteral administration routes, Int Immunopharm, 2014, 23(2): 592-602. (IF: 4.8）

  56. Shaohui Qiu, Qiang Wei, Zhenlun Liang, Guanghui Ma, Lianyan Wang, Wenqi An, Xiaowei Ma, Xin Fang, Peng He, Hemin Li, and Zhongyu Hu(*), Biodegradable polylactide microspheres enhance specific immune response induced by Hepatitis B surface antigen, Hum Vacc Immunother, 2014, 10(8): 2350-2356. (IF: 4.1)

  57. Yuying Liu, Xiaoming Chen, Lianyan Wang(*), Tingyuan Yang, Qipeng Yuan, and Guanghui Ma, Surface charge of PLA microparticles in regulation of antigen loading, macrophage phagocytosis and activation, and immune effects in vitro, Particuology, 2014, 17: 74-80. (IF: 4.1)

  58. Yuan Liu, Guifeng Zhang, Lihong Deng, Jiandu Lei(*), Lianyan Wang, and Jing He, Synthesis characterization and adsorption behavior of molecularly imprinted nanoparticles for tripterine using precipitation polymerization, Anal Methods-UK, 2014, 6(3): 684-689. (IF: 2.7)

  59. HabibaNazir, Weifeng Zhang, Yuan Liu, Xiaoming Chen, Lianyan Wang(*), MM Naseer and Guanghui Ma(*), Silicone oil emulsions: strategies to improve their stability and applications in hair care products, Int J Cosmetic Sci, 2014, 36(2): 124-133. (IF: 2.7)

  60. Tongtong Ma(#), Lianyan Wang(#), Tingyuan Yang, Dong Wang , Guanghui Ma(*), and Siling Wang(*), Homogeneous PLGA-Lipid nanoparticle as a promising oral vaccine delivery system for ovalbumin, Asian J Pharm Sci, 2014, 9: 129 -136.(IF: 10.7)

  61. Lianyan Wang(*), Yuan Liu, Weifeng Zhang, Xiaoming Chen, Tingyuan Yang, and Guanghui Ma, Microspheres and microcapsules for protein delivery: strategies of drug activity retention, Curr Pharm Design, 2013, 19(65): 6340-6352. (IF: 2.6）

  62. Yuan Liu, Ying Yin, Lianyan Wang(*), Weifeng Zhang, Xiaoming Chen, Xiaoxiao Yang, Junjie Xu, and Guanghui Ma(*), Surface hydrophobicity of microparticles modulates adjuvanticity, J Mater Chem B, 2013, 1(32): 3888-3896. (IF: 6.1)

  63. Yuan Liu, Ying Yin, Lianyan Wang(*), Weifeng Zhang, Xiaoming Chen, Xiaoxiao Yang, Junjie Xu(*), and Guanghui Ma(*), Engineering Biomaterial-Associated Complement Activation to Improve Vaccine Efficacy, Biomacromolecules, 2013, 14(9): 3321-3328. (IF: 5.5)

  64. Zhan Zhou, Jing Zhang, Lijing Sun, Guanghui Ma, Zhiguo Su, Comparison of site-specific PEGylations of the N-terminus of interferon beta-1b: selectivity, efficiency, and in vivo/vitro activity. Bioconjug Chem. 2014, 25(1):138-46.  (IF: 4.0)

  65. Qiang Li, Rongyue Zhang, Jua Li, Xiaofeng Yan, Lianyan Wang, Fangling Gong, Zhiguo Su, and Guanghui Ma(*), In situ inhibitor (HCl) removal promoted heterogeneous Friedel-Crafts reaction of polystyrene microsphere with Lewis acids catalysts, J MolCatal A-Chem, 2013, 37: 53-65. 

  66. Lianyan Wang(*), Tingyuan Yang, Jian Yang, Qiang Li, DongxiaHao, Juanjuan Yang and Guanghui Ma(*), In situ Magnetization Technique for Synthesis of Magnetic Polymer Microspheres, Powder Technol, 2013, 235(5): 1017-1024. (IF: 4.5)

  67. HabibaNazir, Lianyan Wang(*), GuopingLian, Shiping Zhu Yueling Zhang, Yuan Liu, and Guanghui Ma(*), Multilayered Silicone Oil Droplets of Narrow Size Distribution: Preparation and Improved Deposition on Hair, Colloid Surface B, 2012, 100: 42-49. (IF: 5.4)

  68. Hua Yue, Wei Wei, Bei Fan, Zhanguo Yue, Lianyan Wang, Guanghui Ma(*), and Zhiguo Su(*), The orchestration of cellular and humoral responses is facilitated by divergent intracellular antigen trafficking in nanoparticle-based therapeutic vaccine, Pharmacol Res, 2012, 65(2): 189-197. (IF: 9.1)

  69. Rongyue Zhang, Qiang Li, Jing Zhang, Juan Li, Guanghui Ma, Zhiguo Su，Preparation of poly (ethylene glycol) acrylate grafted polystyrene resin for solid-phase peptide synthesis. Reactive and Functional Polymers, 2012,72(10): 773-780. (IF: 4.5)

  70. Piping Lv, Wei Wei, Hua Yue, Tingyuan Yang, Lianyan Wang, and Guanghui Ma(*), Porous quaternized chitosan nanoparticles containing paclitaxel nanocrystals improved therapeutic efficacy in non-small-cell lung cancer after oral administration, Biomacromolecules, 2011, 12(12): 4230-4239. (IF: 5.5)

  71. Zhanguo Yue, Wei Wei, Piping Lv, Hua Yue, Lianyan Wang, Zhiguo Su, and Guanghui Ma(*), Surface charge affects cellular uptake and intracellular trafficking of chitosan-based nanoparticles, Biomacromolecules, 2011, 12(7): 2440-2446. (IF: 5.5)

  72. Yueling Zhang, Wei Wei, Piping Lv, Lianyan Wang(*), and Guanghui Ma(*), Preparation and evaluation of alginate-chitosan microspheres for oral delivery of insulin, Eur J Pharm Biopharm, 2011, 77(1): 11-19. (IF: 4.4)

  73. Yi Wei, Yuxia Wang(*), Lianyan Wang, DongxiaHao, and Guanghui Ma(*), Fabrication strategy for amphiphilic microcapsules with narrow size distribution by premix membrane emulsification, Colloid Surface B, 2011, 87(2): 399-408. (IF: 5.4)

  74. HabibaNazir, Piping Lv, Lianyan Wang(*), GuopingLian, Shiping Zhu, and Guanghui Ma(*), Uniform-sized silicone oil microemulsions: Preparation, investigation of stability and deposition on hair surface, J Colloid Interf Sci, 2011, 364(1): 56-64. (IF: 9.4) 

  75. Yueling Zhang, XingyuanJia, Lianyan Wang(*), Jingzhong Liu, and Guanghui Ma(*), Preparation of Ca-Alginate Microparticles and Its Application for Phenylketonuria Oral Therapy, Ind Eng Chem Res, 2011, 50(7): 4106-4112. (IF: 3.8)

  76. Wei Wei, Guanghui Ma(*), Lianyan Wang, Jie Wu, and Zhiguo Su, Hollow quaternized chitosan microspheres increase the therapeutic effect of orally administered insulin, Acta Biomater, 2010, 6 (1): 205-209. (IF: 9.4)

  77. Hua Yue, Wei Wei, Zhanguo Yue, Piping Lv, Lianyan Wang, Guanghui Ma(*), and Zhiguo Su(*), Particle size affects the cellular response in macrophages, Eur J Pharm Sci, 2010, 41(5): 650-657. (IF: 4.3)

  78. Jian Yang, DongxiaHao, Caixia Bi, Zhiguo Su, Lianyan Wang(*), and Guanghui Ma(*), Rapid synthesis of uniform magnetic microspheres by combing premix membrane emulsification and in situ formation techniques, Ind Eng Chem Res, 2010, 49(13): 6047-6053. (IF: 3.8) 

  79. Guanghui Ma(*), Jian Yang, Piping Lv, Lianyan Wang, Wei Wei, Rui Tian, Jie Wu , Zhiguo Su, Preparation of uniform microspheres and microcapsules by modified emulsification process, Macromol Symposia, 2010, 288: 41-48. 

  80. Piping Lv, Wei Wei, Fangling Gong, Yueling Zhang, Huiying Zhao, Jiandu Lei, Lianyan Wang(*), and Guanghui Ma(*), Preparation of Uniformly Sized Chitosan Nanospheres by a Premix Membrane Emulsification Technique, Ind Eng Chem Res, 2009, 48(19): 8819-8828. (IF: 3.8)

  81. Wei Wei, Lan Yuan, Gang Hu, Lianyan Wang, Jie Wu, Xue Hu, Zhiguo Su, and Guanghui Ma(*), Monodisperse chitosan microspheres with interesting structures for protein drug delivery, Adv Mater, 2008, 20(12): 2292-2296. (SCI, IF: 27.4)

  82. Qingzhu Zhou, Lianyan Wang, Guanghui Ma(*), and Zhiguo Su, Multi-stage premix membrane emulsification for preparation of agarose microbeads with uniform size, J Membrane Sci, 2008, 322(1): 98-104. (IF: 8.4)

  83. Jing Zhang, Zhiguo Su, Guanghui Ma, Synthesis and characterization of heterotelechelic poly(ethylene glycol)s with amino acid at one end and hydroxyl group at another end, Journal of Applied Polymer Science, 2008, 110, 2432-2439. (IF: 2.7)

  84. Wei Wei, Lianyan Wang, Lan Yuan, Xiaoda Yang, Zhiguo Su, and Guanghui Ma(*), Bioprocess of uniform-sized crosslinked chitosan microspheres in rats following oral administration, Eur J Pharm Biopharm, 2008, 69(3): 878-886. (IF: 4.4)

  85. Jie Wu, Wei Wei, Lianyan Wang, Zhiguo Su, and Guanghui Ma(*), Preparation of uniform-sized pH-sensitive quaternized chitosan microsphere by combining membrane emulsification technique and thermal-gelation method, Colloid Surface B, 2008, 63(2): 164-175. (IF: 5.4)

  86. Qiang Wei, Wei Wei, Bo Lai, Lianyan Wang, Yuxia Wang, Zhiguo Su, and Guanghui Ma(*), Uniform-sized PLA nanoparticles: Preparation by premix membrane emulsification, Int J Pharm, 2008, 359(1-2): 294-297. (IF: 5.3)

  87. Qiang Wei, Wei Wei, Rui Tian, Lianyan Wang, Zhiguo Su, and Guanghui Ma(*), Preparation of uniform-sized PELA microspheres with high encapsulation efficiency of antigen by premix membrane emulsification, J Colloid Interf Sci, 2008, 323(2): 267-273. (IF: 9.4)

  88. Yueling Zhang, GuopingLian, Shiping Zhu, Lianyan Wang, Wei Wei, and Guanghui Ma(*), Investigation on the uniformity and stability of sunflower oil/water emulsions prepared by SPG membrane, Ind Eng Chem Res, 2008, 47(17): 6412-6417. (IF: 3.8)

  89. Wei Wei, Lianyan Wang, Lan Yuan, Qiang Wei, Xiaoda Yang, Zhiguo Su, and Guanghui Ma(*), Preparation and Application of Novel Microspheres Possessing Autofluorescent Properties, Adv Funct Mater, 2007, 17(16): 3153-3158. (IF: 18.5)

  90. Jing Zhang, Yongjiang Zhao, Zhiguo Su, Guanghui Ma, Synthesis of monomethoxy poly(ethylene glycol) without diol poly(ethylene glycol). Journal of Applied Polymer Science, 2008, 105, 3780-3786. (IF: 2.7)

  91. Jie Wu, Wei Wei, Lianyan Wang, Zhiguo Su, and Guanghui Ma(*), A thermosensitive hydrogel based on quaternized chitosan and poly(ethylene glycol) for nasal drug delivery system, Biomaterials, 2007, 28(13): 2220-2232. (IF: 12.8)

  92. Qingzhu Zhou, Lianyan Wang, Guanghui Ma(*), and Zhiguo Su, Preparation of uniform-sized agarose beads by microporous membrane emulsification technique, J Colloid Interf Sci, 2007, 311(1): 118-127. (IF: 9.4)

  93. Lianyan Wang, YonghongGu, Qingzhu Zhou, Guanghui Ma(*), Yinhua Wan, and Zhiguo Su, Preparation and characterization of uniform-sized chitosan microspheres containing insulin by membrane emulsification and a two-step solidification process, Colloid Surface B, 2006, 50(2): 126-135. (IF: 5.4)

  94. Lianyan Wang, YonghongGu, Zhiguo Su, and Guanghui Ma(*), Preparation and improvement of release behavior of chitosan microspheres containing insulin, Int J Pharm, 2006, 311(1-2); 187-195. (IF: 5.3)

  95. Lianyan Wang, GuanghuiMa(*), and Zhiguo Su, Preparation of uniform sized chitosan microspheres by membrane emulsification technique and application as carrier of protein drug, J Control. Release, 2005, 106(1-2): 62-75. (IF: 10.5)

  96. 张亚茹，王慧梅，迟永杰，高媛，赵颖，暴佳欣，张竞，王连艳(*)，mRNA疫苗及其基于聚合物的递送系统研究进展，中国生物工程杂志，2023,43（5）：55-68。

  97. 暴佳欣，王连艳(*)，周志茂，张竞，朱艳华，壳聚糖复合微球吸附水中药物污染物的研究进展，工业用水与废水，2023，54（1）：1-5。

  98. 赵颖，许克新，胡浩，王慧梅，王连艳(*)，纳米递药系统在膀胱功能障碍性疾病及膀胱肿瘤治疗中的研究进展，中国医药工业杂志，2022，53（12）：118-126。

  99. 袁晓凡，赵晓玫，管庆磊，菊苣川牛膝复合物增强小鼠免疫力的研究，中医临床研究，2022，15(4)：60-64。

  100. 刘雪，张竞， 梁博， 张耀， 王伟颖， 张纯， 刘永东 ，多肽与化疗药物偶联提高药物的有效性和安全性，过程工程学报，2021，21（11）：1245-1258。

  101. 高媛,邢文馨,王慧梅.大孔树脂纯化岩高兰多酚的工艺研究[J].植物研究, 2021, 41(04): 626-632. 

  102. 王东，霍元子，王连艳，阎雪莹，常秀莲，赵思奇，周亮，彭孝明，杨婷媛，艾塞那肽口服给药PLGA/SA微球的制备，维吾尔医药，2020，2：171-174。

  103. 王红芳，王连艳，杨婷媛，殷瑛，阎雪莹，DDAB/PLA 纳米颗粒佐剂浓度对免疫效果的影响，现代预防医学，2018，45（14）：2603-2609。

  104. 王慧梅，范艳敏，王连艳，基于微胶囊技术对油脂包埋的研究进展，现代食品科技，2018，34（10）：1-11。

  105. 马文颜，康磊，王连艳，霍焱，申镐源，王艳萍(*)，131I标记卵清蛋白及其载131I-OVA的PLGA /DDAB纳米粒SPECT显像，科学技术与工程，2018，18（8）：27-33。

  106. 江苗苗， 张 竞， 鲁勖琳，C群和W135群流脑结合疫苗的制备及其初步免疫评价，过程工程学报，2018,18 (6): 1283-1292.

  107. 张宇，王连艳，王艳萍(*)，嗜酸乳杆菌微胶囊制备及工艺优化，食品与发酵工业，2018，44（06）：1-13。

  108. 邱越佳，孟丹，杨婷媛，王连艳，朱艳华(*)，口服载胰岛素PLGA 纳米球的制备及初步药效学评价，中国医药工业杂志，2018，49（5）:614-621。

  109. 王海霖，贾吉磊，王连艳，杨婷媛，朱艳华，靶向DC抗肿瘤疫苗制剂的研究进展，赤子，2018，441：158-158。

  110. 孟丹，邱越佳，杨婷媛，王连艳，王硕，朱艳华(*)，马光辉，聚合物脂质纳米球的制备优化，现代生物医学进展，2018，18（10）：1887-1891。

  111. 高媛,李慧敏,赵彤彤,孙艳涛.罗汉果饮料的研制研究[J].食品安全质量检测学报,2018,9(14):3760-3764.

  112. 徐璐， 张竞， 余蓉， 苏志国，大肠杆菌表达CRM197及其在通用流感疫苗中的应用，过程工程学报， 2017,17 (5): 1054-1058.

  113. 余瑾瑜 孔英俊 张焱 张竞 杨小雁 张贵锋 苏志国 王明林，氧化硅片表面配基疏水性及白附行为的影响，过程工程学报， 2016, (5): 774 -780。

  114. 张博，王瑛，王启宝，杨婷媛，张贵锋，王连艳(*)，快速膜乳化法制备尺寸均一的载硫酸亚铁明胶微球，过程工程学报，2015，15（4）：847-853。

  115. 刘雁南，王连艳(*)，杨婷媛，刘艳辉，马光辉，白油佐剂粒径均一性与炎症和免疫学效应相关性，过程工程学报，2015，15（4）：653-658。

  116. 徐婧，王连艳(*)，杨婷媛，刘艳辉，马光辉，聚乳酸纳米颗粒的制备与表征，过程工程学报，2015，15（3）：495-500。

  117. 何超群，杨婷媛(*)，王连艳，张贵锋，齐峰，张嵘，马光辉，SD大鼠Ⅱ型糖尿病模型的建立与评价，过程工程学报，2015（3）:501-505。

  118. 王东，王连艳，常秀莲，杨婷媛(*)，马光辉，提高蛋白多肽口服生物利用度的方法，过程工程学报，2014，14（2）：354-360。

  119.  贾成成，王连艳(*)，方颖，陈健平，曹科，刘永江，马光辉，PLGA微球粒径对HPV L1 五聚体候选疫苗免疫效果的调控，过程工程学报，2013，12（4）：638-644。

  120. 刘玉莹，陈小明，王连艳(*)，袁其朋，马光辉，鱼精蛋白对PLA微球佐剂的调控，过程工程学报，2013，13（4）：646-653。

  121. 李修乐，刘琳，高建萍，张竞，孔英俊，王明林，张贵锋，苏志国，PEG化rhG-CSF的修饰位点识别研究，药物生物技术，2013，04，348-352。

  122. 蔡明明，王连艳(*)，吕丕平，马光辉，朱宝成，壳聚糖季铵盐表面修饰对载紫杉醇PLGA 微球体外药效学的影响，过程工程学报，2012，12（3）：86-91。

  123. 宋春艳，王连艳(*)，吴有斌，张竞，马光辉，张栩，壳聚糖微球的自发荧光机理，过程工程学报，2011， 11（3）：487-491。

  124. 李娜，王连艳(*)，吴有斌，曾烨靖，马光辉，苏志国，乙肝表面抗原在微球表面的吸附行为、活性和结构变化，过程工程学报， 2010，10（3）：559-567。

  125. 曾烨靖，王连艳(*)，马光辉，马润宇，快速膜乳化法制备载紫杉醇聚乳酸类微球，过程工程学报，2010，10（3）：568-575。

  126. 田瑞，王连艳(*)，吴颉，张洁，曾烨婧，马光辉，利用快速膜乳化法制备粒径均一的PLGA纳微球和纳微囊，过程工程学报， 2009，9(4)：754-762。

  127. 李鹏， 梁洪， 张竞， 苏志国，2-氯三苯甲基氯树脂的制备及其在多肽固相合成中的应用，过程工程学报， 2009， 9 (3): 558-562.

  128. 梁洪，李鹏 ， 张竞， 苏志国，聚苯乙烯基质RNA固相有机合成载体的制备与性能表征，过程工程学报， 2009， 9 (4): 770-775。

  129. 古永红，王连艳，谭天伟，马光辉(*)，尺寸均一的壳聚糖微球的制备及其作为胰岛素控释载体的研究，生物工程学报， 2006，22(1)：150-155。

  130. 王连艳，马光辉(*)，疫苗控释微球研究进展，国外医学-预防、诊断、治疗用生物制品分册，2004，27(2)：78-83。