张道宏，女，中共党员，博士生导师，食品学院食品安全与营养系教授。陕西省青年科技新星，国家自然科学基金委员会项目评议专家，陕西省科技计划项目评审专家，全国优秀博士学位论文提名获得者。Sensors & Actuators B: Chemical、Analytical Chemistry、Journal of Agricultural and Food Chemistry、Talanta、Food Chemistry、Food Control、Food analytical methods、Materials Express等杂志审稿人。
一、主要研究方向
主要从事食品中有毒有害物质的识别及免疫学快速检测技术研究
二、工作、学习情况
2022.01-至今，西北农林科技大学，食品科学与工程学院，教授
2021.05-2021.11，韩国汉阳大学（Hanyang University），访问学者
2015.1-2021.12，西北农林科技大学食品科学与工程学院，副教授
2011.7-2014.12，西北农林科技大学食品科学与工程学院，讲师
2008.9-2011.7，中国农业科学院，武汉油料作物研究所，农产品质量与食物安全，农学博士，导师：李培武院士
2004.9-2007.7，华中农业大学，动物科技与动物医学院，预防兽医，农学硕士，导师：石德时教授
2000.9-2004.7，山东农业大学，动物科技学院，动物医学，农学学士
三、独立开设课程
独立开设本科生《实验动物学》理论及实验课程、研究生《研究生实验动物学》的理论课程。
四、取得的研究成果和目前正在进行的科学研究工作
（一）主持和参与的科研项目
1.主持项目
[11] 基于信号放大及双识别的模式化食源性致病菌多元快速检测研究，国家自然科学基金面上项目（31972150），2020.1-2023.12，主持，经费58万元。
[10] 基于新型生物探针的免疫层析技术对畜产品中雌二醇残留的快速检测研究，陕西省重点研发计划项目—一般项目，2019NY-109，2019.01-2021.12，主持，经费10万元。
[9] 食品安全关键快检技术装备的开发及规范化研究，陕西省科技厅重点研发计划产业创新链（群）项目-社会发展领域（2019ZDLSF07-08），2019.12.1-2022.03.31，子项目负责人，经费8万元。
[8] 国家自然科学基金青年基金（31201357），2013.1-2015.12。主持，经费23万元。
[7] 陕西省科学技术研究发展计划农业攻关项目（2014K02-13-03），2014.1-2015.12。主持，经费10万元。
[6] 陕西省青年科技新星计划项目（2014KJXX-42），2014.1-2016.12。主持，经费10万元。
[5] 新疆自治区高技术研究发展计划项目（201317106），2013.1-2015.12。子项目负责人，经费3万元。
[4] 西北农林科技大学博士启动基金（2011BSJJ077），2012.1-2014.12。主持，经费5万元。
[3] 校基本科研业务费专项资金项目（QN2013061），2013.1-2015.12。主持，经费10万元。
[2] 陕西省专项配套经费，2014.1-2016.12，主持，经费5万元。
[1] 校基本科研业务费专项资金校青年培育专项项目，(2452015397)，2015.08-2015.12，主持，经费4万元。
2.参与项目
[7] 基于超顺磁性纳米材料免疫层析的二元沙门氏菌食物中毒快速检测研究，（广东省科技厅）广东省自然基金面上项目，2020.1-2023.12，主要参与人员，经费10万元
[6] 国家自然科学基金（21675127），基于不对称原生细胞模型的食源性致病菌智能化检测方法研究。2017年1月-2020年12月。主要参与人员，经费60万元。
[5] 国家自然科学基金面上项目，C200702，芹菜素对食品污染物3-MCPD所致肾损伤的保护作用及机制研究，2016/01-2019/12，主要参与人员，经费60万元。
[4] 国家自然科学基金（31201286），HSPB8在棒曲霉毒素引起的人胚肾细胞毒性中的作用及控制机理，2013.1-2015.12，主要参与人员，经费23万元。
[3] 国家科技支撑计划子课题（2012BAK17B06），猕猴桃产品农药残留的全产业链识别、溯源与控制技术研究，2012.1-2014.12，主要参与人员，经费15万元。
[2] 陕西省科学技术研究发展计划项目（2012KJXX-17），畜产品中β-受体激动剂药物残留多联检试纸条快速检测方法研究，2012.1-2014.12，主要参与人员，经费20万元。
[1] “十二五”国家科技计划课题（2012BAH30F03），功能因子检测技术体系研究与构建，2012.1-2014.12，主要参与人员，经费30万元。
（二）论文发表情况（通讯作者/第一作者）
[37] Man Zhao, Xiaolin Yao, Sijie Liu, Han Zhang, Lulu Wang, Xuechi Yin, Lihong Su, Baocheng Xu, Jianlong Wang, Quanxue Lan*, Daohong Zhang*. Antibiotic and mammal IgG based lateral flow assay for simple and sensitive detection of Staphylococcus aureus. Food Chemistry, 2021, (339): 127955. （一区，Top期刊，IF=6.306）
[36] Sijie Liu, Leina Dou, Xiaolin Yao, Wentao Zhang, Man Zhao, Xuechi Yin, Jing Sun, Daohong Zhang*, Jianlong Wang*. Nanozyme amplification mediated on-demand multiplex lateral flow immunoassay with dual-readout and broadened detection range. Biosensors & Bioelectronics, 2020 (169): 112610.（一区，IF=10.257）
[35] Daohong Zhang, Lingzhi Yan, Yongzhi Zhang, Tao Li and Jianlong Wang* . An ultra simple and cost-effective µPAD by pasting hydrophilic channels to a hydrophobic basement. Food frontiers, 2020: 1-8.
[34] Zonghan Wang, Xiaolin Yao, Yongzhi Zhang, Rong Wang, Yanwei Ji, Jing Sun, Daohong Zhang⁎, Jianlong Wang⁎. Functional nanozyme mediated multi-readout and label-free lateral flflow immunoassay for rapid detection of Escherichia coli O157:H7. Food Chemistry. 2020 (329): 127224.（一区，IF=6.306）
[33] Leina Dou, Linpin Luo, Xu Zhang, Wentao Zhang, Lizhi Liu, Xuechi Yin, Sijie Liu, Jing Sun, Daohong Zhang*, Jianlong Wang*. Biomimetic cell model for fluorometric and smartphone colorimetric dual-signal readout detection of bacteria toxin. Sensors & Actuators B: Chemical. 2020, 312:127956.（一区，IF=7.1）
[32] Sijie Liu, Leina Dou, Xiaolin Yao, Bingxin Zhao, Zonghan Wang, Jing Sun, Daohong Zhang*, Jianlong Wang*. Polydopamine nanospheres as high-affinity signal tag towards lateral flow immunoassay for sensitive furazolidone detection. Food Chemistry, 2020 (315): 126310. (一区，IF= 6.306)
[31] Lihong Su, Lulu Wang, Xiaolin Yao, Xuechi Yin, Han Zhang, Man Zhao, Sijie Liu, Zonghan Wang, Jianlong Wang, Daohong Zhang*. Small size nanoparticles—Co3O4 based lateral flow immunoassay biosensor for highly sensitive and rapid detection of furazolidone. Talanta, 2020,（二区，TOP期刊，IF=5.339）
[30] Tong Bu, Lingzhi Yan, Qiong Huang, Leina Dou, Bingxin Zhao, Lunjie Huang, Qingfeng Yang, Na Hu, Baowei Yang, Yourui Suo, Jianlong Wang* and Daohong Zhang*. Dual Recognition Strategy and Magnetic Enrichment based Lateral Flow Assay toward Pathogen Bacteria Detection. Talanta, 2020(206): 120204.（二区，TOP期刊，IF=5.339）
[29] Yinge Li, Xue Fu, Wenxin Zhu, Jiandong Gong, Jing Sun, Daohong Zhang*, Jianlong Wang*. Self-ZIF template-directed synthesis of a CoS nanoflflake array as a Janus electrocatalyst for overall water splitting†. Inorg. Chem. Front., 2019, 6, 2090–2095.（二区，IF=5.958）
[28]Tong Bu#, Jianlong Wang#,Leina Dou, Bingxin Zhao, Tao Li and Daohong Zhang*. New functional tracers-two dimensional nanosheets based immunochromatographic assay for Salmonella enteritidis detection. Journal of Agricultural and Food Chemistry, 2019, 67, 6642−6649.（一区，IF=4.192）
[27] Xiaolin Yao, Zonghan Wang, Leina Dou, Bingxin Zhao, Yixin He, Jianlong Wang, Jing Sun, Tao Li, Daohong Zhang*. An innovative immunochromatography assay for highly sensitive detection of 17β-estradiol based on an indirect probe strategy. Sensors & Actuators B: Chemical, 2019 (289): 48-55.（一区，IF=7.1）
[26]Qiong Huang, Bingxin Zhao, Tong Bu, Lingzhi Yan, Leina Dou, Qingfeng Yang, Jianlong Wang and Daohong Zhang*. Immunoassay of clenbuterol with bacteria as natural signal carriers for signal amplification. Sensors & Actuators B: Chemical, 2019 (288): 210-216.（一区，IF=7.1）
[25] Zonghan Wang, Xiaolin Yao, Rong Wang, Yanwei Ji, Tianli Yue, Jing Sun, Tao Li, Jianlong Wang*, Daohong Zhang*. Label-free strip sensor based on surface positively charged nitrogen-rich carbon nanoparticles for rapid detection of Salmonella enteritidis. Biosensors & Bioelectronics, 2019 (132): 360–367.（一区，IF=10.257）
[24] Leina Dou, Tong Bu, Wentao Zhang, Bingxin Zhao, Qingfeng Yang, Lunjie Huang, Sihang Li, Chengyuan Yang, Jianlong Wang, Daohong Zhang*. Chemical-staining based lateral flow immunoassay: A nanomaterials-free and ultra-simple tool for a small molecule detection. Sensors & Actuators B: Chemical, 2019 (279): 427–432.（一区，IF=7.1）
[23] Tong Bu, Qiong Huang, Lingzhi Yan, Wentao Zhang, Leina Dou, Lunjie Huang, Qingfeng Yang, Bingxin Zhao, Baowei Yang, Tao Li, Jianlong Wang and Daohong Zhang*. Applicability of biological dye tracer in strip biosensor for ultrasensitive detection of pathogenic bacteria. Food Chemistry, 2019 (274): 816-821. (一区，IF= 6.306)
[22] Mengyue Zhang, Lingzhi Yan, Qiong Huang, Tong Bu, Shaoxuan Yu, Xubo Zhao, Jianlong Wang, Daohong Zhang*. Highly sensitive simultaneous detection of major ochratoxins by an immunochromatographic assay. Food Control, 2018 (84), 215-220. (一区，IF= 4.258)
[21] Tong Bu, Lingzhi Yan, Qiong Huang, Lunjie Huang, Mengyue Zhang, Qingfeng Yang, Baowei Yang, Jianlong Wang* and Daohong Zhang*. Ultra technically-simple and sensitive detection for Salmonella Enteritidis by immunochromatographic assay based on gold growth. Food Control, 2018 (84)：536–543. (一区，IF=4.258)
[20] Leina Dou, Bingxin Zhao, Tong Bu, Wentao Zhang, Qiong Huang, Lingzhi Yan, Lunjie Huang, Yanru Wang, Jianlong Wang and Daohong Zhang*. Highly sensitive detection of a small molecule by a paired labels recognition system based lateral flow assay. Analytical and Bioanalytical Chemistry, 2018, 410 (13): 3161–3170. (二区，IF=3.637)
[19] Lingzhi Yan, Leina Dou, Tong Bu, Qiong Huang, Rong Wang, Qingfeng Yang, Lunjie Huang, Jianlong Wang* and Daohong Zhang*. Highly sensitive furazolidone monitoring in milk by a signal amplified lateral flow assay based on magnetic nanoparticles labeled dual-probe. Food Chemistry, 2018, 261:131-138. (一区，IF=6.306)
[18] Qiong Huang, Tong Bu, Wentao Zhang, Lingzhi Yan, Mengyue Zhang, Qingfeng Yang, Lunjie Huang, Baowei Yang, Na Hu, Yourui Suo, Jianlong Wang* and Daohong Zhang*. An improved clenbuterol detection by immunochromatographic assay with bacteria@Au composite as signal amplifier. Food Chemistry, 2018, 262:48-55. (一区，IF= 6.306)
[17] Bingxin Zhao, Qiong Huang, Leina Dou, Tong Bu, Kai Chen, Qingfeng Yang, Lingzhi Yan, Jianlong Wang, Daohong Zhang*. Prussian blue nanoparticles based lateral flow assay for high sensitive determination of clenbuterol. Sensors & Actuators B: Chemical, 2018 (275): 223–229. （一区，IF=7.1）
[16] Yuanyuan Xue,# Wentao Zhang#, Mengyue Zhang, Lizhi Liu, Wenxin Zhu, Lingzhi Yan, Jing Wang, Yanru Wang, Jianlong Wang*, Daohong Zhang*. Development of a paper-based microfluidic analytical device by a more facile hydrophobic substrate generation strategy. Analytical Biochemistry, 2017 (525)：100–106. (四区，IF=2.877)
[15] Wei Liu#, Daohong Zhang#, Wenxin Zhu, Sikai Zhang, Yashan Wang, Shaoxuan Yu, Tao Liu, Xiao Zhang, Wentao Zhang, Jianlong Wang*. Colorimetric and visual determination of total nereistoxin-related insecticides by exploiting a nereistoxin-driven aggregation of gold nanoparticles. Microchim Acta, 2015 (182): 401–408. (二区，IF=6.232)
[14] Shaoxuan Yu, Wentao Zhang, Wei Liu, Wenxin Zhu, Ruochen Guo, Yashan Wang, Daohong Zhang* and Jianlong Wang*. The inhibitory effect of selenium nanoparticles on protein glycation in vitro. Nanotechnology, 2015, 26 (14): 145703 (15pp). (三区，IF=3.551)
[13] Tao Liu, Gang Nie, Xiao Zhang, Wei Liu, Wentao Zhang, Yashan Wang, Daohong Zhang*, Jianlong Wang*. Development of a Detection Kit Based on G-Quadruplex DNAzyme for Detection of Lead(II) Ion in Food Samples, Food Analytical Methods, 2015 (8): 1133–1140. (二区，IF=2.667)
[12] Tao Liu, Xiao Zhang, Jianpeng Hao, Wenxin Zhu, Wei Liu, Daohong Zhang*, Jianlong Wang*, Acetylcholinesterase-free colorimetric detection of chlorpyrifos in fruit juice based on the oxidation reaction of H2O2 with chlorpyrifos and ABTS2− catalyzed by hemin/G-quadruplex DNAzyme. Food Analytical Methods, 2015 (8): 1556–1564. (二区，IF=2.667）
[11] Tao Liu, Xiao Zhang, Wenxin Zhu, Wei Liu, Daohong Zhang*, Jianlong Wang*. A G-quadruplex DNAzyme based colorimetric method for facile detection of Alicyclobacillus acidoterrestris. Analyst, 2014 (139): 4315–4321. (二区，IF=3.978)
[10] Yashan Wang#, Daohong Zhang#, Wei Liu, Xiao Zhang, Shaoxuan Yu, Tao Liu, Wentao Zhang, Wenxin Zhu, Jianlong Wang*. Facile colorimetric method for simple and rapid detection of endotoxin based on counterion-mediated gold nanorods aggregation. Biosensor and Bioelectronics, 2014 (55): 242–248. (一区，IF=10.257)
[9] Wenxin Zhu, Wei Liu, Tianbao Li, Xiaoyue Yue, Tao Liu, Wentao Zhang, Shaoxuan Yu, Daohong Zhang*, Jianlong Wang*. Facile green synthesis of graphene-Au nanorod nanoassembly for online extraction and sensitive stripping analysis of methyl parathion. Electrochimica Acta, 2014 (146): 419–428. (二区，TOP期刊，IF=6.215)
[8] Daohong Zhang, Peiwu Li, Wei Liu , Lei Zhao, Qi Zhang, Wen Zhang, Xiaoxia Ding, Jianlong Wang*. Development of a detector-free semiquantitative immunochromatographic assay with major aflatoxins as target analytes. Sensors and Actuators B-chemical, 2013 (185): 432–437. (一区，IF=7.1）
[7] Daohong Zhang, Peiwu Li*, Qi Zhang, Ran Li, Wen Zhang, Xiaoxia Ding, Changming Li. A naked-eye based strategy for semiquantitative immunochromatographic assay. Analytica Chimica Acta, 2012 (740): 74–79. (二区，IF=5.977）
[6] Daohong Zhang, Peiwu Li*, Qi Zhang, Yang Yang, Wen Zhang, Di Guan and Xiaoxia Ding. Extract-free immunochromatographic assay for on-site tests of aflatoxin M1 in milk. Analytical Methods, 2012 (4), 3307–3313. (四区，IF=2.596）
[5] Daohong Zhang, Peiwu Li*, Qi Zhang, Wen Zhang. Ultrasensitive nanogold probe-based immunochromatographic assay for simultaneous detection of total aflatoxins in peanuts. Biosensor and Bioelectronics, 2011 (26): 2877–2882. (一区，IF=10.257）
[4] Daohong Zhang, Peiwu Li*, Yang Yang, Qi Zhang, Wen Zhang, Zhi Xiao, Xiaoxia Ding. A high selective immunochromatographic assay for rapid detection of aflatoxin B1. Talanta, 2011 (85): 736–742. (二区，TOP期刊，IF=5.339）
[3] Daohong Zhang, Peiwu Li*, Qi Zhang, Wen Zhang, Yanling Huang, Xiaoxia Ding, Jun Jiang. Production of ultrasensitive generic monoclonal antibodies against major aflatoxins using a modified two-step screening procedure. Analytica Chimica Acta, 2009 (636): 63–69. (二区，IF=5.977）
[2] Juan Jiang#; Daohong Zhang#; Wen Zhang; Xiupin Wang; Ye Kong; Qi Zhang*; Peiwu Li*. Preparation, Identification, and Preliminary Application of Monoclonal Antibody Against Pyrethroid Insecticide Fenvalerate, Analytical Letters, 2010, 43: 2773–2789. （四区，IF=1.467）
[1]张道宏，李培武，张奇，张文，丁小霞，王秀嫔，姜俊.污染粮油食品的主要真菌毒素及胶体金免疫层析技术在快速检测中的应用．中国油料作物学报，2010，32（4）：577–582。
（中文核心期刊）
（三）专利申请及获批情况
[10]张道宏，赵曼，姚晓琳，王璐璐，张涵.一种金黄色葡萄球菌检测试纸条，检测方法及应用。申请号：202010294483.6，申请日期：2020.4.15。
[9]张道宏，窦磊娜，王建龙，补彤，黄琼，闫灵芝，赵兵欣，赵东阳。一种生物探针，检测呋喃唑酮的试纸条及其应用。申请号：201710552301.9
[8]张道宏，黄琼，王建龙，补彤，闫灵芝，赵兵欣，窦磊娜，赵东阳.一种生物探针，检测盐酸克伦特罗的试纸条及应用，专利号：ZL201710553195.6，授权日期：2019.8.9
[7]张道宏，补彤，王建龙，黄琼，闫灵芝，窦磊娜，赵兵欣，赵东阳。一种肠炎沙门氏菌的检测方法及其检测试纸条，专利号：ZL201710553197.5，授权日期：2019.8.9
[6]王建龙，张道宏，补彤，闫灵芝，黄琼，窦磊娜，赵兵欣，赵东阳。一种灵敏探针及制备方法和利用其检测肠炎沙门氏菌的方法，专利号：ZL201710733861.4，授权日期：2019.9.6
[5]武运，薛媛媛，张道宏，王建龙，朱文新，张文涛，于少轩，王帅星，张玉环，王靖。一种纸基微流控芯片的制备方法，专利号：ZL201510426713.9，授权日期：2018.9.28
[4] Peiwu Li, Daohong Zhang, Qi Zhang, Wen Zhang, Xiaoxia Ding, Jun Jiang, Xiaomei Chen. Digital immunochromatographic test strip for semi-quantitative detection of aflatoxin B1 and preparation method thereof, United States Patent, US 2012/0034711 A1
[3] 李培武，张道宏，张奇，张文，丁小霞，姜俊，陈小媚. 快速检测黄曲霉毒素总量的高灵敏度免疫层析试纸条及其制备方法，2012，中国，ZL201010245801
[2]李培武，张道宏，张奇，张文，丁小霞，姜俊，陈小媚. 半定量化检测黄曲霉毒素B1的多检测线免疫层析试纸条及其制备方法，2012，中国，ZL201010245094
[1]李培武，张道宏，张奇，张文，管笛，丁小霞，姜俊.黄曲霉毒素M1免疫层析试纸条及其制备方法，2012，中国，ZL201110062947
（四）著作
Peiwu Li, Qi Zhang, Daohong Zhang, Di Guan, Xiaoxia Ding, Xuefen Liu, Sufang Fan, Xiupin Wang, Wen Zhang. Aflatoxin Measurement and Analysis (Chapter 11). Aflatoxins-Detection, Measurement and Control, ISBN 978-953-307-711-6, InTech (Croatia). Editor: Irineo Torres-Pacheco, 2011（著作）
五、获得荣誉情况
[6] 食品安全危害因子快速识别与控制技术研究，2019年3月荣获陕西高等学校科学技术奖一等奖，5/7
[5] 2019年论文“Highly sensitive detection of a small molecule by a paired labels recognition system based lateral flow assay”荣获陕西省第十四届自然科学优秀论文三等奖（通讯作者）
[4] 2014年荣获陕西省科技新星荣誉称号
[3] 2014年荣获全国优秀博士学位论文提名
[2]李培武，李鑫，张道宏，张奇，张文，丁小霞，姜俊，陈小媚。杂交瘤细胞株1C11，其产生的抗黄曲霉毒素通用单克隆抗体及其应用。中国专利优秀奖，2014.11。
[1] 2012年获中国农业科学院优秀博士毕业论文奖
六、联系方式
通讯地址：陕西杨凌西农路28号 西北农林科技大学食品学院邮编：712100
联系电话：18009248948，Email：zhangdh@nwsuaf.edu.cn