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成果及论文

13. Total synthesis of ()-deglycocadambine

Wang, F.-X.*; Chen, Y.-T.; Liu, H.; Wang, H.-S.; Liang, H.; Chen, Z.-F.; Chi, Y. R.*

Org. Chem. Front. 2024, 11, 48694873. https://pubs.rsc.org/en/content/articlelanding/2024/qo/d4qo01122h


12. Total Synthesis of Quebrachamine and Kopsiyunnanine D

Liu, H.; Yuan, W.; Ran, M.-Y.; Wei, G.; Zhao, Y.; Liao, Z.-Q.; Liang, H.; Chen, Z.-F.*; Wang, F.-X.*

J. Org. Chem. 2024, 89, 59055910. https://pubs.acs.org/doi/abs/10.1021/acs.joc.4c00363


11. Divergent syntheses of ()-carvone-derived dimers

Liu, J.-J.; Zhang, B.-Q.; She, K.; Ran, J.; Li, H.-F.; Wang, H.-S.*; Wang, F.-X.* 

Tetrahedron 2024, 151, 133804. https://www.sciencedirect.com/science/article/pii/S0040402023006063


10. Design and Synthesis of Novel Indole Ethylamine Derivatives as a Lipid Metabolism Regulator Targeting PPARα/CPT1 in AML12 Cells

Liu, Y.-C.;  Wei, G.; Liao, Z.-Q.; Wang, F.-X.; Zong, C.; Qiu, J.; Le, Y.; Yu, Z.-L.; Yang, S. Y.; Wang, H.-S.; Dou, X.-B.*; Wang, C.-Y.*

Molecules 2024, 29, 12. https://www.mdpi.com/1420-3049/29/1/12

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9. Assembly of multicyclic isoquinoline scaffolds from pyridines: formal total synthesis of fredericamycin A  

Wang, F.-X.; Yan, J.-L.; Liu, Z.; Zhu, T.; Liu, Y.; Ren, S.-C.; Lv, W.-X.; Jin, Z.; Chi, Y. R.*  

Chem. Sci. 202112, 10259−10265. https://pubs.rsc.org/en/content/articlehtml/2021/sc/d1sc02442f


8. Carbene-Catalyzed Alkylation of Carboxylic Esters via Direct Photoexcitation of Acyl Azolium Intermediates

Ren, S.-C.; Lv, W.-X.; Yang, X.; Yan, J.-L.; Xu, J.; Wang, F.-X.; Hao, L.; Chai, H.; Jin, Z.; Chi, Y. R.*  

ACS. Catal. 202111, 2925−2934. https://pubs.acs.org/doi/abs/10.1021/acscatal.1c00165

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7. Total Synthesis of Lycopodium Alkaloids Palhinine A and Palhinine D

Wang, F.-X.; Du, J.-Y.; Wang, H.-B.; Zhang, P.-L.; Zhang, G.-B.; Yu, K.-Y.; Zhang, X.-Z.; An, X.-T.; Cao, Y.-X.; Fan, C.-A.*

J. Am. Chem. Soc. 2017139, 4282−4285. https://pubs.acs.org/doi/abs/10.1021/jacs.6b13401  


6. Enantioselective Synthesis of Functionalized 4-Aryl Hydrocoumarins and 4-Aryl Hydroquinolin-2-ones via Intramolecular Vinylogous Rauhut–Currier Reaction of para-Quinone Methides

Zhang, X.-Z.; Gan, K.-J.; Liu, X.-X.; Deng, Y.-H.; Wang, F.-X.; Yu, K.-Y.; Zhang, J.; Fan, C.-A.*  

Org. Lett. 201719, 3207−3210. https://pubs.acs.org/doi/abs/10.1021/acs.orglett.7b01331


5. Tandem Spirocyclopropanation/Rearrangement Reaction of Vinyl p-Quinone Methides with Sulfonium Salts: Synthesis of Spirocyclopentenyl p-Dienones

Zhang, X.-Z.; Deng, Y.-H.; Gan, K.-J.; Yan, X.; Yu, K.-Y.; Wang, F.-X.; Fan, C.-A.*  

Org. Lett. 201719, 1752−1755. https://pubs.acs.org/doi/abs/10.1021/acs.orglett.7b00516  


4. Diastereoselective and Enantioselective Synthesis of Unsymmetric β,β-Diaryl-α-Amino Acid Esters via Organocatalytic 1,6-Conjugated Addition of para-Quinone Methides

Zhang, X.-Z.; Deng, Y.-H.; Yan, X.; Yu, K.-Y.; Wang, F.-X.; Ma, X.-Y.; Fan. C.-A.*  

J. Org. Chem. 201681, 5655−5662. https://pubs.acs.org/doi/abs/10.1021/acs.joc.6b00390  


3. A Strategic Study Towards Constructing the Nine-Membered Azonane Ring System of Palhinine A via an Azidoketol Fragmentation Reaction

Wang, F.-X.; Zhang, P.-L.; Wang, H.-B.; Zhang, G.-B.; Fan, C.-A.*

Sci. China Chem. 201659, 1188−1196. https://link.springer.com/article/10.1007/s11426-016-0059-7


2. Asymmetric Catalytic 1,6-Conjugated Addition/Aromatization of para-Quinone Methides: Enantioselective Introduction of Functionalized Diarylmethine Stereogenic Centers

Chu, W.-D.; Zhang, L.-F.; Bao, X.; Zhao, X.-H.; Zeng, C.; Du, J.-Y.; Zhang, G.-B.; Wang, F.-X.; Ma, X.-Y.; Fan, C.-A.*  

Angew. Chem. Int. Ed. 201352, 9229−9233. https://onlinelibrary.wiley.com/doi/abs/10.1002/anie.201303928


1. Toward the Total Synthesis of Palhinine A: Expedient Assembly of Multifunctionalized Isotwistane Ring System with Contiguous Quaternary Stereocenters

Zhang, G.-B.; Wang, F.-X.; Du, J.-Y.; Qu, H.; Ma, X.-Y.; Wei, M.-X.; Wang, C.-T.; Li, Q.; Fan, C.-A.*  

Org. Lett. 201214, 3696−3699. https://pubs.acs.org/doi/abs/10.1021/ol301534r