部分近年发表文章：

(22）#Important# Rapid Formation of Intramolecular Disulfide Bridges using Light: An Efficient Method to Control the Conformation and Function of Bioactive Peptides. He F.^#, Chai Y.^#, Zeng Z., Lu F., Chen H., Zhu J., Fang Y.,Cheng K., Miclet E., Alezra V.,  Wan Y.*. J. Am. Chem. Soc. 2023,DOI:10.1021/jacs.3c07795.

(21)   Liu, P.; Cheng, M.; Guo, J.; Cao, D.; Luo, J.; Wan, Y.; Fang, Y.; Jin, Y.; Xie, S.-S.; Liu, J. Dual Functional Antioxidant and Butyrylcholinesterase Inhibitors for the Treatment of Alzheimer’s Disease: Design, Synthesis and Evaluation of Novel Melatonin-Alkylbenzylamine Hybrids. Bioorg. Med. Chem. 2023, 78, 117146.

(20)   Yang, Z.; Luo, G.; Ying, Y.; Li, H.; Wan, Y.; Xu, G.; Li, M.; Xian, Y.; Feng, Y.; Fang, Y. Novel 2,6-Disubstituted Benzofuran-3-One Analogues Improve Cerebral Ischemia/Reperfusion Injury via Neuroprotective and Antioxidative Effects. Bioorganic Chem. 2023, 132, 106346. 

(19) #Important# Customized Reversible Stapling for Selective Delivery of Bioactive Peptides. Zeng, Z.^#; Zhu, J.^#; Deng, X.; Chen, H.; Jin, Y.; Miclet, E.; Alezra, V.; Wan, Y.* J. Am. Chem. Soc. 2022,144, 23614-23621. 

Highlighted in X-MOL; 化学加；多肽加；江西中医药大学官网

(18)     Guo, J.; Cheng, M.; Liu, P.; Cao, D.; Luo, J.; Wan, Y.; Fang, Y.; Jin, Y.; Xie, S.-S.; Liu, J. A Multi-Target Directed Ligands Strategy for the Treatment of Alzheimer’s Disease: Dimethyl Fumarate plus Tranilast Modified Dithiocarbate as AChE Inhibitor and Nrf2 Activator. Eur. J. Med. Chem. 2022, 242, 114630.

(17)     Guo, J.; Cheng, M.; Liu, P.; Cao, D.; Luo, J.; Wan, Y.; Wang, R.; Fang, Y.; Jin, Y.; Zhang, Z.; Xie, S.; Liu, J. Design, Synthesis and Anti‐Tumor Activity Evaluation of Novel 3,4‐(Methylenedioxy)Cinnamic Acid Amide‐Dithiocarbamate Derivatives. Chem. Biodivers. 2022, 19 (8).

(16)     Guo, J.; Xu, A.; Cheng, M.; Wan, Y.; Wang, R.; Fang, Y.; Jin, Y.; Xie, S.-S.; Liu, J. Design, Synthesis and Biological Evaluation of New 3,4-Dihydro-2(1H)-Quinolinone-Dithiocarbamate Derivatives as Multifunctional Agents for the Treatment of Alzheimer’s Disease. Drug Des. Devel. Ther. 2022, 16, 1495–1514.

(15)     Yuan, S.; Zhang, L.; Ji, L.; Zhong, S.; Jiang, L.; Wan, Y.; Song, Y.; Zhang, C.; Wang, R. FoxO3a Cooperates with RUNX1 to Promote Chondrogenesis and Terminal Hypertrophic of the Chondrogenic Progenitor Cells. Biochem. Biophys. Res. Commun. 2022, 589, 41–47.

(14)   Zhang, Z.; Cheng, M.; Guo, J.; Wan, Y.; Wang, R.; Fang, Y.; Jin, Y.; Xie, S.-S.; Liu, J. Design, Synthesis and Biological Evaluation of Novel Pyrazolone Derivatives as Selective Butyrylcholinesterase Inhibitors with Antioxidant Activity against Alzheimer’s Disease. J. Mol. Struct. 2022, 1254, 132319. 

(13) Polymyxin B-Inspired Non-Hemolytic Tyrocidine A Analogues with Significantly Enhanced Activity against Gram-Negative Bacteria: How Cationicity Impacts Cell Specificity and Antibacterial Mechanism. Zhu, J.^#; Hu, C.^#; Zeng, Z.; Deng, X.; Zeng, L.; Xie, S.; Fang, Y.; Jin, Y.; Alezra, V.; Wan, Y.*  Eur. J. Med. Chem., 2021, 221, 113488. 

(12) Antimicrobial Peptides: Triumphs and Challenges. Zeng, Z.-Z.^#; Huang, S.-H.^#; Alezra, V.*; Wan, Y.*Future Med. Chem. 2021,13(16),1313-1315. (Invited review)

(11)   Zhang, Z.; Guo, J.; Cheng, M.; Zhou, W.; Wan, Y.; Wang, R.; Fang, Y.; Jin, Y.; Liu, J.; Xie, S.-S. Design, Synthesis, and Biological Evaluation of Novel Xanthone-Alkylbenzylamine Hybrids as Multifunctional Agents for the Treatment of Alzheimer’s Disease. Eur. J. Med. Chem. 2021, 213, 113154. 

(10) Gramicidin S Inspired Cyclopeptidomimetics as Potent Membrane-Active Bactericidal Agents with Therapeutic Potential. Hu, C.^#; Wen, Q.^#; Huang, S.; Xie, S.; Fang, Y.; Jin, Y.; Campagne, R.; Alezra, V.; Miclet, E.; Zhu, J.*; Wan, Y.* ChemMedChem, 2021, 16 (2), 368–376.

(9)     Ding, J.; Liu, J.; Zhang, Z.; Guo, J.; Cheng, M.; Wan, Y.; Wang, R.; Fang, Y.; Guan, Z.; Jin, Y.; Xie, S.-S. Design, Synthesis and Biological Evaluation of Coumarin-Based N-Hydroxycinnamamide Derivatives as Novel Histone Deacetylase Inhibitors with Anticancer Activities. Bioorganic Chem. 2020, 101, 104023. 

(8) Development of Therapeutic Gramicidin S Analogues Bearing Plastic β,γ‐Diamino Acids. Guan, Q.^#; Chen, K.^#; Chen, Q.; Hu, J.; Cheng, K.; Hu, C.; Zhu, J.; Jin, Y.; Miclet, E.; Alezra, V.; Wan, Y.* ChemMedChem, 2020, 15 (12), 1089–1100.

(7)     Fang, Y.; Xiong, L.; Hu, J.; Zhang, S.; Xie, S.; Tu, L.; Wan, Y.; Jin, Y.; Li, X.; Hu, S.; Yang, Z. Synthesis and Evaluation of Novel Fused Pyrimidine Derivatives as GPR119 Agonists. Bioorganic Chem. 2019, 86, 103–111.

(6)   #Important# Recent Advances in the Exploration of Therapeutic Analogues of Gramicidin S, an Old but Still Potent Antimicrobial Peptide. Guan, Q.^#; Huang, S.^#; Jin, Y.; Campagne, R.; Alezra, V.; Wan, Y.*J. Med. Chem. 2019, 62 (17), 7603–7617.(Invited Review)

(5)   Unexpected Dimerization of a Tripeptide Comprising a β,γ-Diamino Acid. Wan, Y.; Baltaze, J.-P.; Kouklovsky, C.; Miclet, E.; Alezra, V.  J. Pept. Sci. 2019, 25 (2), e3143.

(4)   β,γ-Diamino Acids as Building Blocks for New Analogues of Gramicidin S: Synthesis and Biological Activity. Wan, Y.; Stanovych, A.; Gori, D.; Zirah, S.; Kouklovsky, C.; Alezra, V.  Eur. J. Med. Chem. 2018, 149, 122–128.

(3)   Constrained Cyclic β,γ-Diamino Acids from Glutamic Acid: Synthesis of Both Diastereomers and Unexpected Kinetic Resolution. Wan, Y.; Auberger, N.; Thétiot-Laurent, S.; Bouillère, F.; Zulauf, A.; He, J.; Courtiol-Legourd, S.; Guillot, R.; Kouklovsky, C.; Cote des Combes, S.; Pacaud, C.; Devillers, I.; Alezra, V.  Eur. J. Org. Chem. 2018, 2018 (3), 329–340.

(2)     王超杰; 万阳; 宋卫强; 陆群. 常山酮中间体的合成工艺改进. 合成化学 2016, 24 (1), 79–83.

(1)     万阳; 文鹏; 张攀; 陆群. 化学与生物转化法合成帕立骨化醇. 有机化学 2012, 32 (10), 1988–1992.