课题组近5年主要论文成果：
SCI：
1. Jingfeng Liu, Xiaoying Shi , Rongjun Zhang, Miaomiao Zhang, Juan He, Jian Che , Zheng Wang and Qingwen Wang*.CoFe2O4-Quantum Dots for Synergistic Photothermal/Photodynamic Therapy of Non-small-Cell Lung Cancer Via Triggering Apoptosis by Regulating PI3K/AKT Pathway.Nanoscale Research Letters.IF:4.702，JCR:Q2
2. Yiping Hu,Juan He,Lianhua He,Bihua Xu,Qingwen Wang*.Expression and function of Smad7 in autoimmune and inflammatory diseases.Journal of Molecular Medicine.2021;99(6).IF:4.101.JCR:Q2
3. Xian Lin, Xiongzhou Zheng, Baihua Yang ,Jian Chen, Qin Xu, Qingwen Wang*，
Clinical significance and immune landscapes of
stemness-related and immune gene set-based signature in oral cancer.Clinical and Translational Medicine.IF:11.492,JCR:Q1
4. Chunfang Liua, Lianhua He, Jingxia Wanga , Qianqian Wanga , Congcong Suna , Yiqun Lia, Kexin Jiaa , Jinxia Wanga , Tengteng Xua , Ruirui Minga , Qingwen Wangb, Na Lina,∗Anti-angiogenic effffect of Shikonin in rheumatoid arthritis by downregulating PI3K/AKT and MAPKs signaling pathways.Journal of Ethnopharmacology.Available online 01 June 2020.IF:4.360,JCR:Q2
5. Zhengyu Fang, Jiyang Lv, Jing Wang, Qingxia Qin, Juan He, Meiying Wang, Gengmin Zhou, Guoyu Liu, Fubo Zhong , Yadan Zheng, Hui-Yao Lan* and Qingwen Wang*。C-Reactive Protein Promotes the Activation of Fibroblast-Like Synoviocytes From Patients With Rheumatoid Arthritis.Frontiers in Immunology.20 May 2020.IF:7.561,JCR:Q2
6. Yiping Hu,Tiantian Zhang, Jingqin Chen, WenXiang Cheng, Jianhai Chen, Zhengtan Zheng, Jietao Lin,Guoyuan Zhu, Yong Zhang,Xueling Bai,Yan Wang, Bing Song, Qingwen Wang*,Ling Qin, and Peng Zhang.Downregulation of Hypoxia-Inducible Factor-1a by RNA Interference Alleviates the Development of Collagen-Induced Arthritis in Rats.Molecular Therapy-Nucleic Acids.Vol. 19 March 2020.IF：8.886,JCR:Q1
7. Lianhua He, Qingxia Qin, Juan He, HanWang, Yiping Hu, Wencheng He,1Bihua Xu, Gengmin Zhou, Hongying Shan, Bo Yang, and Qingwen Wang* .Ermiao San inhibits angiogenesis in rheumatoid arthritis by suppressing JAK/STAT signaling pathways.Evidence-Based Complementary and Alternative Medicine.Volume 2020, Article ID 4381212.IF:2.629,JCR:Q2
8. Bi Hua Xu , Jingyi Sheng , Yong Ke You , Xiao Ru Huang , Ronald C.W. Ma ,Qingwen Wang, Hui Yao Lan .Deletion of Smad3 prevents renal fifibrosis and inflflammation in type 2 diabetic nephropathy.Metabolism Clinical and Experimental 103 (2020) 154013.IF:8.694,JCR:Q1
9. Han Wang, Yuxuan Wang, Yundi Tang, Xuewu Zhang, Hua Ye, Gengmin Zhou, Jiyang Lv, Zhanguo Li, Jianping Guo, Qingwen Wang*.Frequencies of the LILRA3 6.7-kb deletion are highly differentiated among Han Chinese subpopulations, and involved in ankylosing spondylitis predisposition.Frontiers in Genetics.Manuscript ID: 454492.2019-9.IF:4.599，JCR:Q2
10. JingJing Sun,Xue Li,Haotian Zhou,Xiaoyun Liu,Jingjing Jia,Qizhi Xie, Sijia Peng,Xiaolin Sun,Qingwen Wang* and Li Yi.Anti-GAPDH autoantibody is associated with increased disease activity and intracranial pressure in systemic lupus erythematosus.Journal of Immunology Research.2019.3.31.doi,org/10.1155/2019/7430780.IF:4.818，JCR:Q2
11. Gengmin Zhou1 , Xiaolin Sun , Qingxia Qin, Jiyang Lv, Yueming Cai , Meiying Wang , Rong Mu, Hui Y. Lan*, Qingwen Wang*.Loss of Smad7 promotes inflammation in rheumatoid arthritis. Frontiers in Immunology. 2018.10.25.IF:7.561,JCR:Q2
12. Zhengyu Fang, Dongyi He, Bo Yu, Feng Liu, Jianping Zuo, Yuxia Li, Qi Lin, Xiaodong Zhou,* Qingwen Wang,*. High-Throughput Study of the Effects of Celastrol on Activated Fibroblast-Like Synoviocytes from Patients with Rheumatoid Arthritis. 2017, 8, 221; doi:10.3390/genes8090221.IF:4.096，JCR:Q2
13. Chen J, Li W, Cui K, Ji K, Xu S, Xu Y *. Artemisitene suppresses tumorigenesis by inducing DNA damage through deregulating c-Myc-topoisomerase pathway. Oncogene. 2018, 37(37): 5079-5087.（TOP期刊，中科院1区，IF: 9.867）
14. Liu J #, Huang X #, Liu D #, Ji K, Tao C *, Zhang R *, Chen J *. Demethyleneberberine induces cell cycle arrest and cellular senescence of NSCLC cells via c-Myc/HIF-1α pathway, Phytomedicine. 2021, 153678.（TOP期刊，中科院1区，IF: 5.34，通讯作者）
15. Lin X, Zheng X, Yang B, Chen J *, Xu Q *, Wang Q *. Clinical significance and immune landscapes of stemness-related and immune gene set-based signature in oral cancer. Clin Transl Med, 2021, 11 (2): e343.（TOP期刊，中科院1区，IF: 11.492，通讯作者）
16. Chen J #, Zhang R #, Tao C #, Huang X, Chen Z, Li X, Zhou J, Zeng Q, Zhao B, Yuan M *, Ma M *, Wu Z *. CuS-NiS2 nanomaterials for MRI guided phototherapy of gastric carcinoma via triggering mitochondria-mediated apoptosis and MLKL/CAPG-mediated necroptosis. Nanotoxicology. 2020, 14(6):774-787. （TOP期刊，中科院1区，IF: 5.913）
17. Chen J #, Tao C #, Huang X #, Chen Z, Wang L, Li X, Ma M *, Wu Z *. CT2-3, a novel magnolol analogue suppresses NSCLC cells through triggering cell cycle arrest and apoptosis. Bioorg Med Chem. 2020, 28(6): 115352.（IF: 3.641）
18. Tao C #, Chen J #, Huang X, Chen Z, Li X, Li Y, Xu Y *, Ma M *, Wu Z *. CT1-3, a 1 novel magnolol-sulforaphane hybrid suppresses tumorigenesis through inducing mitochondria-mediated apoptosis and inhibiting epithelial mesenchymal transition. Eur J Med Chem. 2020, 199 (2020):112441.（共同一作，TOP期刊，中科院1区，IF:6.514）
19. Zhang R #, Chen J #, Mao L, Guo Y, Hao Y, Deng Y, Han X, Li Q *, Liao W *, Yuan M *. Nobiletin triggers ROS-mediated pyroptosis through regulating autophagy in ovarian cancer cells. J Agric Food Chem. 2020, 68(5): 1326-1336. (共同一作，TOP期刊，中科院1区，IF: 5.279)
20. Chen J #, Huang X #, Tao C #, Wang L, Chen Z, Li X, Zeng Q, Ma M *, Zhang R *, Wu Z *. Berberine chloride suppresses non-small cell lung cancer by deregulating Sin3A/TOP2B pathway in vitro and in vivo. Cancer Chemother Pharmacol. 2020, 86(1):151-61.（IF: 3.333）
21. Chen J #, Huang X #, Tao C, Xiao T, Li X, Zeng Q, Ma M *, Wu Z *. Artemether attenuates the progression of non-small cell lung cancer by inducing apoptosis, cell cycle arrest and promoting cellular senescence. Biol Pharm Bull. 2019, 42(10): 1720-1725.（IF: 2.223）
22. Chen J #, Zhang R, Wang J, Yu P, Liu Q, Zeng D, Song H, Kuang Z *. Protective effects of Baicalin on LPS-induced injury in intestinal epithelial cells and intercellular tight junctions. Can J Physiol Pharmacol. 2015, 93(4): 233-7.（IF: 2.273）
23. Liu J, Shi X, Zhang R, Zhang M, He J, Chen J *, Wang Z *, Wang Q *. CoFe2O4-Quantum Dots for Synergistic Photothermal/Photodynamic Therapy of Non-small-Cell Lung Cancer Via Triggering Apoptosis by Regulating PI3K/AKT Pathway. Nanoscale Res Lett. 2021, 16(1):120. （IF: 4.702）
24. Tao C #, Hu S #, Chen J #, Chen YJ, Sun KH, Cui GZ, Ma M *, Wu ZZ *. Highly efficient synthesis of demethyleneberberine, columbamine and palmatine. Neurochem Int. 2020,139: 104807.（共同一作，中科院 2 区，IF: 3.921）
25. Hu Y, He J, He L, Xu B, Wang Q*, Expression and function of Smad7 in autoimmune and inflammatory diseases, Journal of Molecular Medicine, 2021 May 31. doi: 10.1007/s00109-021-02083-1.
26.Hu Y, Zhang T, Chen J, Cheng W, Chen J, Zheng Z, Lin J, Zhu G, Zhang Y, Bai X, Wang Y, Song B, Wang Q*, Qin L*, Zhang P*, Down-regulation of hypoxia-inducible factor-1α by RNA interference alleviates the development of collagen-induced arthritis in rats, Molecular Therapy-Nucleic Acids, 2020, 19: 1330-1342.
27.Hu Y, Zhang T, Huang H, Cheng W, Lai Y, Bai X, Chen J, Yue Y, Zheng Z, Guo C, Qin L*, Zhang P*, Fracture Healing in a Collagen-Induced Arthritis Rat Model: Radiology and Histology Evidence, Journal of Orthopedic Research, 2018, 36(11): 2876-2885.
28.Hu Y*#, Yang Y#, Luo B*#, Evaluation of destruction in a collagen-induced arthritis rat model: Bony spur formation, Experimental and Therapeutic Medicine, 2017, 14(3): 2563-2567.
29. Hu Y, Li J, Qin L, Cheng W, Lai Y, Yue Y, Ren P, Pan* X, Zhang P*, Study in Treatment of Collagen-Induced Arthritis in DBA/1 Mice Model by Genistein, Current Pharmaceutical Design, 2016, 22(46): 6975-6981.
30.X. Lin#, A. Li#, Y. Li#, R. Luo#, Y. Zou, Y. Liu, C. Liu, Y. Xie, S. Zuo, Z. Liu, Z. Liu* and W. Fang*. Silencing MYH9 blocks HBx-induced GSK3β ubiquitination anddegradation to inhibit tumor stemness in hepatocellular carcinoma [J]. Signal Transduct Target Ther, 2020, 5(1): 13. 31.X. Lin, X. Zheng, B. Yang, J. Chen*, Q. Xu* and Q. Wang*. Clinical significance and immune landscapes of stemness-related and immune gene set-based signature in oral cancer [J]. Clin Transl Med, 2021, 11(2): e343. 32.X. Lin#, S. Zuo#, R. Luo#, Y. Li#, G. Yu, Y. Zou, Y. Zhou, Z. Liu, Y. Liu, Y. Hu, Y. Xie, W. Fang* and Z. Liu*. HBX-induced miR-5188 impairs FOXO1 to stimulate β-catenin nuclear translocation and promotes tumor stemness in hepatocellular carcinoma [J]. Theranostics, 2019, 9(25): 7583-7598. 33.Y. Zou#, X. Lin#, J. Bu#, Z. Lin, Y. Chen, Y. Qiu, H. Mo, Y. Tang, W. Fang* and Z. Wu*. Timeless-Stimulated miR-5188-FOXO1/β-Catenin-c-Jun Feedback Loop Promotes Stemness via Ubiquitination of β-Catenin in Breast Cancer [J]. Mol Ther, 2020, 28(1): 313-327. 34.Y. Li#, X. Liu#, X. Lin#, M. Zhao#, Y. Xiao, C. Liu, Z. Liang, Z. Lin, R. Yi, Z. Tang, J. Liu, X. Li, Q. Jiang, L. Li, Y. Xie, Z. Liu* and W. Fang*. Chemical compound cinobufotalin potently induces FOXO1-stimulated cisplatin sensitivity by antagonizing its binding partner MYH9 [J]. Signal Transduct Target Ther, 2019, 4: 48.
中文核心期刊：
1. 何莲花，栾慧杰，单宏颖，杨波，何娟，虎义平，戴嘉婧，万汇娟，方崇州，王庆文*.防己黄芪汤对DBA/1 小鼠胶原诱导型关节炎及血管新生的影响.中国实验方剂学杂志.2021-07-07
2. 曾沛英、王庆文*.生物制剂治疗强直性脊柱炎的长期疗效观察.中华风湿病学杂志.2021-05-16
3. 钟剑球、曾沛英、王庆文*.类风湿关节炎合并淋巴水肿2例及文献回顾.北京大学学报医学版.2020.12.31
4. 何莲花，覃清霞，吴青，栾慧杰，何娟，何文成，王庆文*.防己黄芪汤对脐静脉内皮细胞功能的影响.中国实验方剂学杂志.2020-11-25
5. 高吉, 何娟, 王庆文, 刘万里.单克隆抗体技术的诞生、现状和展望.科学通报.2020-10-30
6. 许丹妮、王庆文*.混合性结缔组织病合并肺间质病变或肺动脉高压的危险因素分析.中西医结合心脑血管病杂志.2020.07.23
7. 何莲花，王庆文*.二妙散对大鼠骨髓来源的巨噬细胞M1/M2极化的影响.中国实验方剂学杂志.2020-01-19
8. 何莲花，王庆文*.二妙散对TNF-α诱导的人类风湿关节炎成纤维样滑膜细胞功能的影响.中国实验方剂学杂志.2019-11-19
9. 刘国钰，郑雅丹，戴嘉婧，王庆文*，方征宇.羟氯喹通过核因子-κB信号通路抑制类风湿关节炎成纤维样滑膜细胞白细胞介素-6的表达.中国药物与临床.2019-09-02
10. 曾沛英，王庆文*.合并高尿酸血症的强直性脊柱炎患者的临床分析.中华风湿病学杂志.2019-07-19
11. 曾沛英，王庆文*.73例强直性脊柱炎合并心电图异常患者临床分析.汕头大学医学院学报.2019-04-11
12. 曾沛英，王庆文*.糖皮质激素在强直性脊柱炎治疗中的临床观察.山西医药杂志.2019-03-29
13. 朱乙声，王庆文*.全身骨显像在脊柱关节病临床随访中的应用观察.山西医药杂志.2019, 48(2):131-135
14. 王庆文. “二孩”时代再提重视风湿免疫病患者的围生育期管理. 中华风湿病学杂志.2018 ,22(2)
15. 刘凤，王庆文*，方征宇等.甲氨蝶呤对C反应蛋白在类风湿关节炎致炎作用的影响. 中国药物与临床. 2016，16（6）：628-632
16. 罗俊佳，王庆文*.MICA基因多态性及其与免疫性疾病相关性的研究进展. 中国药物与临床. 2016，16（6）：661-664
17. 黄小飞，陈子德，陶成 *，陈健 *.厚朴酚衍生物 CT2-3 对结肠癌细胞的抑制作用及其机制，中国实验方剂学杂志,2020, 23: 113-9.（通讯作者）