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成果及论文


4.Lu, Huixu; Ren, Yunfeng; Qi, Yuming; Xu, Mingze; Liang, Fengying; Wang, Ziyuan; Liu, Jieman; Du, Bujie*; Jiang, Xingya*."Overcoming Hepatic Biotransformation Barrier of Gold Nanoparticles via Au-Se Bond for Enhanced In-Vivo Active Targeting" ACS Nano, 2024, 18, 42, 29178–29188(https://doi.org/10.1021/acsnano.4c10700)


3.Peng, Yexi, Yuming Qi, Mingze Xu, Yiqiao Chen, Xiaoxian Wang, Xingya Jiang*, and Bujie Du*. "Early Detection and Noninvasive Staging of Kidney Dysfunction by a PEGylated Conventional Fluorophore via GFR-Sensitive Renal Transport." Bioconjugate Chemistry , 2024, 35(8), 1258-1268. (https://pubs.acs.org/doi/full/10.1021/acs.bioconjchem.4c00312


2. Qi, Yuming, Mingze Xu, Huixu Lu, Xiaoxian Wang, Yexi Peng, Ziyuan Wang, Fengying Liang, Xingya Jiang,* and Bujie Du*. "Hepatic Biotransformation of Renal Clearable Gold Nanoparticles for Noninvasive Detection of Liver Glutathione Level via Urinalysis." Angewandte Chemie International Edition, 2024,63, e202409477. (https://onlinelibrary.wiley.com/doi/full/10.1002/anie.202409477)


1. Xu, Mingze, Yuming Qi, Gaoshuo Liu, Yuanqing Song, Xingya Jiang*, and Bujie Du*. "Size-Dependent In Vivo Transport of Nanoparticles: Implications for Delivery, Targeting, and Clearance." ACS Nano, 2023, 17(21). 20825-20849. (https://pubs.acs.org/doi/abs/10.1021/acsnano.3c05853) (ESI highly cited)


Prior to joining SCUT:

1、Xingya JiangBujie Du; Jie Zheng*; Glutathione-mediated biotransformation in the liver modulates nanoparticle transport, Nature Nanotechnology, 2019, 14(9): 874-882. (https://www.nature.com/articles/s41565-019-0499-6)


2、Bujie DuXingya Jiang; Anindita Das; Qinhan Zhou; Mengxiao Yu;Rongchao Jin; Jie Zheng*; Glomerular barrier behaves as an atomically precise bandpass filter in a sub-nanometre regime, Nature Nanotechnology, 2017, 12(11): 1096-1102.  ESI Highly Cited Paper(https://www.nature.com/articles/nnano.2017.170) 


3、Bujie Du; Mengxiao Yu; Jie Zheng*; Transport and interactions of nanoparticles in the kidneys, Nature Reviews Materials, 2018, 3(10): 358-374. (https://www.nature.com/articles/s41578-018-0038-3)


4、Xingya Jiang#; Qinhan Zhou#; Bujie Du; Siqing Li; Yingyu Huang; Zhikai Chi; William M. Lee; Mengxiao Yu; Jie Zheng*; Noninvasive monitoring of hepatic glutathione depletion through fluorescence imaging and blood testing, Science Advances, 2021, 7(8): eabd9847.(https://www.science.org/doi/10.1126/sciadv.abd9847)


5、Bujie Du; Yue Chong; Xingya Jiang; Mengxiao Yu; U-Gling Lo; Andrew Dang; Yu-An Chen; Siqing Li; Elizabeth Hernandez; Jason C. Lin; Jer-Tsong Hsieh; Jie Zheng*; Hyperfluorescence Imaging of Kidney Cancer Enabled by Renal Secretion Pathway Dependent Efflux Transport, Angewandte Chemie International Edition, 2020, 60(1): 351-359.  Very Important Paper(https://onlinelibrary.wiley.com/doi/10.1002/anie.202010187)


6、Xingya JiangBujie Du; Shaoheng Tang; Jer-Tsong Hsieh; Jie Zheng*; Photoacoustic Imaging of Nanoparticle Transport in the Kidneys at High Temporal Resolution, Angewandte Chemie International Edition, 2019, 58(18):5994-6000. (https://onlinelibrary.wiley.com/doi/10.1002/anie.201901525)


7、Xingya JiangBujie Du; Yingyu Huang; Jie Zheng*; Ultrasmall noble metal nanoparticles: Breakthroughs and biomedical implications, Nano Today, 2018, 21: 106-125. (https://www.sciencedirect.com/science/article/abs/pii/S1748013218300902)


8、Bujie DuXingya Jiang; Yingyu Huang; Siqing Li; Jason C Lin; Mengxiao Yu; Jie Zheng*; Tailoring Kidney Transport of Organic Dyes with Low-Molecular-Weight PEGylation, Bioconjugate Chemistry, 2020, 31(2): 241-247. ACS Editor's Choice(https://pubs.acs.org/doi/10.1021/acs.bioconjchem.9b00707)


9、Xingya JiangBujie Du; Yingyu Huang; Mengxiao Yu; Jie Zheng*; Cancer Photothermal Therapy with ICG-Conjugated Gold Nanoclusters, Bioconjugate Chemistry, 2020, 31(5): 1522-1528. (https://pubs.acs.org/doi/10.1021/acs.bioconjchem.0c00172)


10、Xingya JiangBujie Du; Mengxiao Yu; Xun Jia; Jie Zheng*; Surface ligand effect on radiosensitization of ultrasmall luminescent gold nanoparticles, Journal of Innovative Optical Health Sciences, 2016, 9(4):1642003. (https://www.worldscientific.com/doi/10.1142/S1793545816420037)


11、Xingya Jiang, Kimia Abedi, Jinjun Shi;Polymeric nanoparticles for RNA delivery, Reference Module in Materials Science and Materials EngineeringElsevier, 2021 https://doi.org/10.1016/B978-0-12-822425-0.00017-8


12、Mendes, Bárbara B., João Conniot, Aviram Avital, Dongbao Yao, Xingya Jiang, Xiang Zhou, Noga Sharf-Pauker et al. "Nanodelivery of nucleic acids." Nature Reviews Methods Primers 2, no. 1 (2022): 1-21. (https://www.nature.com/articles/s43586-022-00104-y)


13、Xiao, Yuling#, Jiang Chen#, Hui Zhou, Xiaodong Zeng, Zhiping Ruan, Zhangya Pu, Xingya JiangAya Matsui, Lingling Zhu, Zohreh Amoozgar, Dean Shuailin Chen, Xiangfei Han, Dan G. Duda*, Jinjun Shi*; Combining p53 mRNA nanotherapy with immune checkpoint blockade reprograms the immune microenvironment for effective cancer therapy. Nature Communications, 2022, 13,758. (https://www.nature.com/articles/s41467-022-28279-8)


14、Liyi Fu, Xianwu Hua, Xingya Jiang, Jinjun Shi*;Multistage Systemic and Cytosolic Protein Delivery for Effective Cancer Treatment, Nano Letters,2022, 22 (1), 111-118 (https://pubs.acs.org/doi/abs/10.1021/acs.nanolett.1c03293)


15、Mengxiao Yu; Jiancheng Zhou; Bujie Du; Xuhui Ning; Craig Authement; Leah Gandee; Payal Kapur; Jer-Tsong Hsieh; Jie Zheng*; Noninvasive Staging of Kidney Dysfunction Enabled by Renal-Clearable Luminescent Gold Nanoparticles, Angewandte Chemie International Edition, 2016, 55(8): 2787-2791. 入选Very Important Paper(https://onlinelibrary.wiley.com/doi/10.1002/anie.201511148)


16、Shaoheng Tang; Chuanqi Peng; Jing Xu; Bujie Du; Qingxiao Wang; Rodrigo D. Vinluan III; Mengxiao Yu; Moon J. Kim; Jie Zheng*; Tailoring Renal Clearance and Tumor Targeting of Ultrasmall Metal Nanoparticles with Particle Density, Angewandte Chemie International Edition, 2016, 55(52):16039-16043. 入选 Very Important Paper(https://onlinelibrary.wiley.com/doi/10.1002/anie.201609043)


17、Chuanqi Peng; Xiaofei Gao; Jing Xu; Bujie Du; Xuhui Ning; Shaoheng Tang; Robert M. Bachoo; Mengxiao Yu; Woo-Ping Ge*; Jie Zheng*; Targeting orthotopic gliomas with renal-clearable luminescent gold nanoparticles, Nano Research, 2017, 10(4): 1366-1376. (https://link.springer.com/article/10.1007/s12274-017-1472-z)


18、Chuanqi Peng; Jing Xu; Mengxiao Yu; Xuhui Ning; Yingyu Huang; Bujie Du; Elizabeth Hernandez; Payal Kapur; Jer-Tsong Hsieh; Jie Zheng*; Tuning the In Vivo Transport of Anticancer Drugs Using Renal-Clearable Gold Nanoparticles, Angewandte Chemie International Edition, 2019, 58(25): 8479-8483. (https://onlinelibrary.wiley.com/doi/10.1002/anie.201903256)


19、Hon S. Leong; Kimberly S. Butler; C. Jeffrey Brinker; May Azzawi; Steve Conlan; Christine Dufés; Andrew Owen; Steve Rannard; Chris Scott; Chunying Chen; Marina A. Dobrovolskaia; Serguei V. Kozlov; Adriele Prina-Mello; Ruth Schmid; Peter Wick; Fanny Caputo; Patrick Boisseau; Rachael M. Crist; Scott E. McNeil; Bengt Fadeel; Lang Tran; Steffen Foss Hansen; Nanna B. Hartmann; Lauge P. W. Clausen; Lars M. Skjolding; Anders Baun; Marlene Agerstrand; Zhen Gu; Dimitrios A. Lamprou; Clare Hoskins; Leaf Huang; Wantong Song; Huiliang Cao; Xuanyong Liu; Klaus D. Jandt; Wen Jiang; Betty Y. S. Kim; Korin E. Wheeler; Andrew J. Chetwynd; Iseult Lynch; Seyed Moein Moghimi; André Nel; Tian Xia; Paul S. Weiss; Bruno Sarmento; José das Neves; Hélder A. Santos; Luis Santos; Samir Mitragotri; Steve Little; Dan Peer; Mansoor M. Amiji; Maria José Alonso; Alke Petri-Fink; Sandor Balog; Aaron Lee; Barbara Drasler; Barbara Rothen-Rutishauser; Stefan Wilhelm; Handan Acar; Roger G. Harrison; Chuanbin Mao; Priyabrata Mukherjee; Rajagopal Ramesh; Lacey R. McNally; Sara Busatto; Joy Wolfram; Paolo Bergese; Mauro Ferrari; Ronnie H. Fang; Liangfang Zhang; Jie Zheng; Chuanqi Peng; Bujie Du; Mengxiao Yu; Danielle M. Charron; Gang Zheng; Chiara Pastore*; On the issue of transparency and reproducibility in nanomedicine, Nature Nanotechnology, 2019, 14(7): 629-635. (https://www.nature.com/articles/s41565-019-0496-9)


20、Jasmine Singh; William Moore; Farjana Fattah; Xingya Jiang; Jie Zheng; Pamela Kurian; Muhammad S. Beg; Saad A. Khan*; Activity and pharmacology of homemade silver nanoparticles in refractory metastatic head and neck squamous cell cancer, Head and Neck - Journal for The Sciences and Specialties of The Head and Neck, 2019, 41(1): E11-E15. (https://onlinelibrary.wiley.com/doi/10.1002/hed.25492)


21、Jing Xu#; Mengxiao Yu#; Chuanqi Peng; Phoebe Carter; Jia Tian; Xuhui Ning; Qinhan Zhou; Qiu Tu; Greg Zhang; Anthony Dao; Xingya Jiang; Payal Kapur; Jer-Tsong Hsieh; Xudong Zhao; Pengyu Liu; Jie Zheng*; Dose dependencies and biocompatibility of renal clearable gold nanoparticles: From mice to non-human primates, Angewandte Chemie International Edition, 2018, 57(1): 266-271. Very Important Paper(https://onlinelibrary.wiley.com/doi/10.1002/anie.201710584)


22、Jinbin Liu#; Paul N. Duchesne#; Mengxiao Yu#; Xingya Jiang; Xuhui Ning; Rodrigo D. Vinluan III; Peng Zhang; Jie Zheng*; Luminescent gold nanoparticles with size-independent emission, Angewandte Chemie International Edition, 2016, 55(31): 8894-8898. (https://onlinelibrary.wiley.com/doi/10.1002/anie.201602795)