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成果及论文

代表性论文:

1.Zhang J, Gao Y, Zhang Z, Zhao J, Jia W, Xia C, Wang F, Liu T. Multi-therapies Based on PARP Inhibition: Potential Therapeutic Approaches for Cancer Treatment. J Med Chem. 2022;65(24):16099-16127.

2.Cao W, Zhu Y, Wu F, Tian Y, Chen Z, Xu W, Liu S, Liu T, Xiong H. Three Birds with One Stone: Acceptor Engineering of Hemicyanine Dye with NIR-II Emission for Synergistic Photodynamic and Photothermal Anticancer Therapy. Small. 2022;18(49):e2204851.

3.Liu Y ,  Li J ,  Zhou G , Liu T. Design, synthesis and anticancer activity studies of novel indole derivatives as Bcl-2/Mcl-1 dual inhibitors. Medicinal Chemistry Research, 2022.

4. Tingting Liu*, Shubin Song, Xu Wang, Jifu Hao. Small-molecule inhibitors of breast cancer-related targets: Potential therapeutic agents for breast cancer. European Journal of Medicinal Chemistry, 2021, 210, 112954. (IF = 7.0, 一区)

5. Zheng Zhang#, Xiaolan Xing#, Peng Guan, Shubin Song, Guirong You, Chengcai Xia, Tingting Liu*. Recent progress in agents targeting polo-like kinases: Promising therapeutic strategies. European Journal of Medicinal Chemistry, 2021, 217, 113314. (IF = 7.0, 一区)

6. Sitao Zhang, Yanzhao Chen, Chengsen Tian, Yujing He, Zeru Tian, Yichao Wan and Tingting Liu*. Dual-target inhibitors based on BRD4: Novel therapeutic approaches for cancer. Current Medicinal Chemistry, 2021, 28, 1775-1795

7. Tingting Liu*, Yichao Wan, Yuliang Xiao, Chengcai Xia, Guiyun Duan. Dual-target inhibitors based on HDACs: Novel antitumor agents for cancer therapy. Journal of Medicinal Chemistry, 2020, 63, 8977-9002. (IF = 8.0, 一区)

8. Tingting Liu*, Zhongyu Wu, Yujing He, Yuliang Xiao, Chengcai Xia. Single and dual target inhibitors based on Bcl-2: Promising anti-tumor agents for cancer therapy. European Journal of Medicinal Chemistry, 2020, 201, 112446-112458. (IF = 7.0, 一区)

9. Yichao Wan*, Chunxing Yan, Han Gao, Tingting Liu*. Small-molecule PROTACs: Novel agents for cancer therapy. Future Medicinal Chemistry, 2020, 12, 1756-8919.

10. Tingting Liu, Gaopan Dong, Feng Xu, Bowen Han, Hao Fang, YunHuang, Yubin Zhou, Lupei Du, Minyong Li*. Discovery of turn-On fluorescent probes for detecting Bcl-2 Protein. Analytical Chemistry, 2019, 91, 5722-5728. (IF = 8.0, 一区)

11. Tingting Liu, Yuqi Gao, Xiaomeng Zhang, Yichao Wan, Lupei Du, Hao Fang, Minyong Li*. Discovery of a turn-On fluorescent probe for myeloid cell leukemia1 protein. Analytical Chemistry, 2017, 89, 11173-11177. (IF = 8.0, 一区)

12. Tingting Liu, Yichao Wan, Renshuai Liu, Lin Ma, Minyong Li, Hao Fang*. Design, synthesis and preliminary biological evaluation of indole-3-carboxylic acid-based skeleton of Bcl-2/Mcl-1 dual inhibitors. Bioorganic & Medicinal Chemistry, 2017, 25, 1939-1948. 

13. Tingting Liu#, Yan Jiang#, Zhenzhen Liu, Jin Li, Kun Fang, Chunlin Zhuang, Lupei Du, Hao Fang, Chunquan Sheng* and Minyong Li*. Environment-sensitive turn-on fluorescent probes for p53-MDM2 protein-protein interaction. MedChemComm, 2017, 8, 1727-1732.