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姬晓彤团队

姬晓彤

女,1990.09,山西晋城,博士,副教授,硕导

E-mailjixiaotong@sxmu.edu.cn

主页:http://www.sxmu.edu.cn/gwxy/info/2007/2077.htm;https://www.x-mol.com/groups/Ji_xiaotong_sxmu

研究方向:环境与健康

学习工作经历

20197-至今,山西医科大学,公共卫生学院,环境卫生教研室;

20139-20197月,山西大学,环境与资源学院,环境生物医学,硕博连读;

20099-20137月,山西大学,环境与资源学院,环境科学,学士。

主持及参与项目:

1.   国家自然科学基金委员会, 青年项目, 22106078,双酚A替代物孕期暴露对子代乳腺发育的影响及其分子机制,2022-01-01至2024-12-31,30万元,在研,主持

2.   山西省基础研究计划项目,青年科学研究项目,20210302124298,双酚A替代物妊娠期暴露对母体乳腺的影响及其分子机制,2022-01-01至2024-12-31,5万元,在研,主持  

3.   山西省教育厅高校科技创新项目,基于气溶胶颗粒暴露与恢复模型探讨采暖周期性肺损伤效应,在研,主持

4.   山西省教育厅,研究生教育创新项目,大气污染物复合暴露诱导小鼠肺部损伤的研究,已结题,主持

5.   山西省教育厅,高等学校教学改革创新项目,常态化疫情防控背景下环境卫生学实验教学智慧化改革研究,在研,主持

6.   国家自然科学基金委员会,面上项目,空气NO2孕期暴露诱导子代肺发育毒性及其作用机制,在研,参加

7.   国家自然科学基金委员会,优秀青年科学基金项目,化学环境污染与健康,已结题,参加

8.   国家自然科学基金委员会,面上项目,孕期二氧化氮(NO2)吸入暴露诱导子代支气管哮喘易感性变化及其分子机制,已结题,参加

代表性论文:(IF2021)

1.    Ji X,  Jiang P, Li Y, Yan W, Yue H. New insights into the effect of bisphenol  AF exposure on maternal mammary glands at various stages of gestation in  mice. Sci Total Environ. 2022; 850:157793. (SCI TOP 1区,IF10.753)

2.    Ji X, Yue H, Li G, Sang N. Maternal smoking-induced lung injuries in dams and offspring via inflammatory cytokines. Environ Int. 2021; 156:106618. (SCI TOP 1区,IF13.352)

3.    Ji X,  Ku T, Zhu N, Ning X, Wei W, Li G, Sang N. Potential hepatic toxicity of  buprofezin at sublethal concentrations: ROS-mediated conversion of  energy metabolism. J Hazard Mater. 2016; 320:176-186. (SCI TOP 1区,IF14.224)

4.    Ji X,  Yue H, Ku T, Zhang Y, Yun Y, Li G, Sang N. Histone modification in the  lung injury and recovery of mice in response to PM2.5 exposure. Chemosphere. 2019; 220:127-136. (SCI TOP 2区,IF8.943)

5.    Ji X,  Han M, Yun Y, Li G, Sang N. Acute nitrogen dioxide (NO2) exposure  enhances airway inflammation via modulating Th1/Th2 differentiation and  activating JAK-STAT pathway. Chemosphere. 2015; 120:722-8. (SCI TOP 2区,IF8.943)

6.    Ji X,  Zhang Y, Ku T, Yun Y, Li G, Sang N. MicroRNA-338-5p modulates pulmonary  hypertension-like injuries caused by SO2, NO2 and PM2.5 co-exposure  through targeting the HIF-1α/Fhl-1 pathway. Toxicol Res (Camb). 2016; 5(6):1548-1560. (SCI 4区,IF2.68)

7.    Ji X, Zhang Y, Li G, Sang N. Potential Role of Inflammation in Associations between Particulate Matter and Heart Failure. Curr Pharm Des. 2018; 24(3):341-358. (SCI 4区,IF3.31)

8.     姬晓彤,岳慧峰,武美琼,白剑英.BPA暴露对本体和子代胰岛β细胞转录组差异对比分析.环境化学,2021,40(02):509-519.

9.     曹舒清,张钰婧,姬晓彤*,郭晨洁.环境化学物暴露与糖尿病肾病发生发展的关联研究. 环境化学,已录用.

10. Yue H, Yang X, Ji X,  Wu X, Li G, Sang N. Time series of transcriptome analysis in entire  lung development stages provide insights into the origin of NO2 related  lung diseases. Environ Int. 2022;168:107454. (SCI TOP 1区,IF13.352)

11. Wu X, Yang X, Geng X, Ji X,  Zhang X, Yue H, Li G, Sang N. Bisphenol A Analogs Induce Cellular  Dysfunction in Human Trophoblast Cells in a Thyroid Hormone  Receptor-Dependent Manner: In Silico and In Vitro Analyses. Environ Sci Technol. 2022. doi: 10.1021/acs.est.1c08161. (SCI TOP 1区,IF11.357)

12. Yue H, Ji X,  Ku T, Li G, Sang N. Sex difference in bronchopulmonary dysplasia of  offspring in response to maternal PM2.5 exposure.  J Hazard Mater. 2020; 389:122033. (SCI TOP 1区,IF14.224)

13. Yan W, Yue H, Ji X,  Li G, Sang N. Prenatal NO2 exposure and  neurodevelopmental disorders in offspring mice: Transcriptomics reveals  sex-dependent changes in cerebral gene expression. Environ Int. 2020; 138:105659. (SCI TOP 1区,IF13.352)

14. Yue H, Ji X, Li G, Hu M, Sang N. Maternal Exposure to PM2.5 Affects Fetal Lung Development at Sensitive Windows. Environ Sci Technol. 2020; 54(1):316-324. (SCI TOP 1区,IF11.357)

15. Yue H, Ji X, Zhang Y, Li G, Sang N. Gestational exposure to PM2.5 impairs vascularization of the placenta. Sci Total Environ. 2019; 665:153-161. (SCI TOP 1区,IF10.753)

16. Zhu N, Geng X, Ji X, Gao R, Li D, Yue H, Li G, Sang N. Gestational exposure to NO<sub>2</sub> aggravates placental senescence. Environ Res. 2022; 212(PtB):113263. (SCI 2区,IF8.431)

17. Zhu N, Ji X, Geng X, Yue H, Li G, Sang N. Maternal PM2.5 exposure and abnormal placental nutrient transport. Ecotoxicol Environ Saf. 2021; 207:111281. (SCI 2区,IF7.129)