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发表的主要文章

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23. Zhang J#, Meng X#, Qin Q, Liang Y, Yang G, Li S, Li X, Zhou JC*, Sun L*. (2024) Evaluation of the Role of Tanshinone I in an In Vitro System of Charcot-Marie-Tooth Disease Type 2N. Int J Mol Sci. 

22. Li S#, Xu T#, Meng X, Yan Y, Zhou Y, Duan L, Tang Y, Zhu L*, Sun L*. (2024) Ocr-mediated suppression of BrxX unveils a phage counter-defense mechanism. Nucleic Acids Res. 

21. Li X#, Si Y#*, Liang J, Li M, Wang Z, Qin Y, Sun L*. (2024) Enhancing bone regeneration and immunomodulation via gelatin methacryloyl hydrogel-encapsulated exosomes from osteogenic pre-differentiated mesenchymal stem cells. J Colloid Interface Sci.

20. Li S, Zhou Y, Yan Y, Qin Y, Weng Q, Sun L*. (2024) Structure-Based Virtual Screening, ADMET Properties Prediction and Molecular Dynamics Studies Reveal Potential Inhibitors of Mycoplasma pneumoniae HPrK/P. Life.

19. Yang G#, Liang Y#, Li X, Li Z, Qin Y, Weng Q, Yan Y, Cheng Y, Qian Y*, Sun L*. (2024) Competitive Inhibition of Okanin against Plasmodium falciparum Tyrosyl-tRNA Synthetase. Int J Mol Sci.

18. Li F#, Shi Z#, Cheng M, Zhou Z, Chu M, Sun L*, Zhou JC*. (2023) Biology and Roles in Diseases of Selenoprotein I Characterized by Ethanolamine Phosphotransferase Activity and Antioxidant Potential. J Nutr.

17. Sun L, Zhou XL, Zhou ZW, Cui H. (2023) Noncanonical functions of Aminoacyl-tRNA synthetases. Front Physiol.

16. Li Z#, Wang W#, Xiao Y#, Du S, Chen Z, Li B, Zhou ZW, Liu K*, Gao F*, Sun L*. (2022) Discovery of a small-molecule inhibitor targeting the ovarian tumor domain of a novel Tamdy orthonairoviruse associated with human febrile illness. J Med Virol.

15. Liu S#, Yan S#, Zhu J, Lu R, Kang C, Tang K, Zeng J, Ding M, Guo Z, Lai X, Jiang Y, Wu S, Zhou L, Sun L*, Zhou ZW*. (2022) Combination RSL3 Treatment Sensitizes Ferroptosis- and EGFR-Inhibition-Resistant HNSCCs to Cetuximab. Int J Mol Sci.

14. Zhong B#, Peng W#, Du S, Chen B, Feng Y, Hu X, Lai Q, Liu S, Zhou ZW, Fang P, Wu Y, Gao F*, Zhou H*, Sun L*. (2022) Oridonin Inhibits SARS‐CoV‐2 by Targeting Its 3C‐Like Protease. Small Science.

13. Zhang J, Zhang H*, Sun L*. (2022) Therapeutic antibodies for COVID-19: is a new age of IgM, IgA and bispecific antibodies coming? MAbs.

12. Feng Y#, Tang K#, Lai Q, Liang J, Feng M, Zhou ZW, Cui H, Du X, Zhang H*, Sun L*. (2022) The Landscape of Aminoacyl-tRNA Synthetases Involved in Severe Acute Respiratory Syndrome Coronavirus 2 Infection. Front Physiol.

11. Zhang H, Yang XL*, Sun L*. (2021) The uniqueness of AlaRS and its human disease connections. RNA Biol.

10. Lu R#, Zhang H#, Jiang YN, Wang ZQ, Sun L*, Zhou ZW*. (2021) Post-Translational Modification of MRE11: Its Implication in DDR and Diseases. Genes.

9. Li J, Wei J, Xu Z, Jiang C, Li M, Chen J, Li Y, Yang M, Gu Y, Wang F, Shu Y*, Yang Y*, Sun L*, Liu Y*. (2021) Cytokine/Chemokine Expression Is Closely Associated Disease Severity of Human Adenovirus Infections in Immunocompetent Adults and Predicts Disease Progression. Front Immunol.

8. Zhang H, Zhou ZW*, Sun L*. (2021) Aminoacyl-tRNA synthetases in Charcot-Marie-Tooth disease: A gain or a loss? J Neurochem.

7. Sun L#, Wei N#, Kuhle B, Blocquel D, Novick S, Matuszek Z, Zhou H, He W, Zhang J, Weber T, Horvath R, Latou P, Pan T, Schimmel P*, Griffin P, and Yang XL*. (2021) CMT2N-causing aminoacylation domain mutants enable Nrp1 interaction with AlaRS. Proc Natl Acad Sci USA.

6. Lu R#, Jiang Y#, Lai X, Liu S, Sun L*, Zhou ZW*. (2021) A Shortage of FTH Induces ROS and Sensitizes RAS-Proficient Neuroblastoma N2A Cells to Ferroptosis. Int J Mol Sci.

5. Blocquel D#Sun L#, Matuszek Z, Li S, Weber T, Kuhle B, Kooi G, Wei N, Baets J, Pan T, Schimmel P*, Yang XL*. (2019) CMT disease severity correlates with mutation-induced open conformation of histidyl-tRNA synthetase, not aminoacylation loss, in patient cells. Proc Natl Acad Sci USA.

4. Zhang H*, Sun L*. (2018) When human cells meet bacteria: precision medicine for cancers using the microbiota. Am J Cancer Res.

3. Sun L, Song Y, Blocquel D, Yang XL, Schimmel P*. (2016) Two crystal structures reveal design for repurposing the C-Ala domain of human AlaRS. Proc Natl Acad Sci USA.

2. Sun L, Gomes AC, He W, Zhou H, Wang X, Pan DW, Schimmel P, Pan T*, Yang XL*. (2016) Evolutionary Gain of Alanine Mischarging to Noncognate tRNAs with a G4:U69 Base Pair. J Am Chem Soc.

1. Sun L#, Wang M#, Lv Z, Yang N, Liu Y, Bao S, Gong W*, Xu RM*. (2011) Structural insights into protein arginine symmetric dimethylation by PRMT5. Proc Natl Acad Sci USA.

 


专利申请

1. 冬凌草甲素和/或其前药在制备抑制SARS-CoV-2的药物中的应用。中国发明专利申请号:202111146675.3

2. 一种含编码塔城蜱病毒2核蛋白基因的融合质粒、宿主及蛋白的制备方法和应用。中国发明专利申请号:202111141732.9

3. 编码布尼亚病毒内罗病毒科核蛋白的核酸、基因和表达载体及其应用。中国发明专利申请号:202110264444.6

4. 腓骨肌萎缩症小鼠模型及其构建方法与应用。中国发明专利申请号:202310176530.0

5. 蛋白质精氨酸甲基转移酶7在促进毛发生长中的应用。中国发明专利申请号:ZLTA20231236