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司星辉 特别研究助理     进组时间: 2015年9月

2011-09 至 2015-06就读于郑州大学化学学院, 2015-09 至 2020-11就读于中国科学技术大学应用化学与工程学院并获得高分子物理与化学博士学位,2020-11至今在长春应化所担任特别研究助理。主持国家自然科学基金青年项目一项,参与国家自然科学基金面上项目3项。


研究方向:

① 抗肿瘤蛋白药物的可控释放与体内递送

② 基于动态交联水凝胶材料的免疫鸡尾酒疗法用于肿瘤治疗及其机制分析

③ 超声可控释放高分子载体材料的设计及其应用

④ 免疫药物的递送模式对免疫药物效力的影响


个人发表论文:

1.Si X, Ji G, Ma S, et al. In–Situ‐Sprayed Dual‐Functional Immunotherapeutic Gel for Colorectal Cancer Postsurgical Treatment[J]. Advanced Healthcare Materials, 2021, 10(20): 2100862. https://doi.org/10.1002/adhm.202100862

2.Si X, Song W, Yang S, et al. Glucose and pH Dual‐Responsive Nanogels for Efficient Protein Delivery[J]. Macromolecular bioscience, 2019, 19(9): 1900148. https://doi.org/10.1002/mabi.201900148.

3.Si X, Ji G, Ma S, et al. Biodegradable implants combined with immunogenic chemotherapy and immune checkpoint therapy for peritoneal metastatic carcinoma postoperative treatment[J]. ACS Biomaterials Science & Engineering, 2020, 6(9): 5281-5289. https://doi.org/10.1021/acsbiomaterials.0c00840.

4.Si X, Ma S, Xu Y, et al. Hypoxia-sensitive supramolecular nanogels for the cytosolic delivery of ribonuclease A as a breast cancer therapeutic[J]. Journal of Controlled Release, 2020, 320: 83-95. https://doi.org/10.1016/j.jconrel.2020.01.021

5.Ji G, Zhang Y, Si X, et al. Biopolymer immune implants’ sequential activation of innate and adaptive immunity for colorectal cancer postoperative immunotherapy[J]. Advanced Materials, 2021, 33(3): 2004559. https:// doi/full/10.1002/adma.202004559