1. Lin S#, Kuang M#. RNA modification-mediated mRNA translation regulation in liver cancer: mechanisms and clinical perspectives. Nature Reviews Gastroenterology & Hepatology. 2024 Jan 19. doi: 10.1038/s41575-023-00884-y.
2. Wei W, Zhang S, Han H, Wang X, Zheng S, Wang Z, Yang C, Wang L, Ma J, Guo S, Wang J, Liu L, Choe J, Lin S. NAT10-mediated ac4C tRNA modification promotes EGFR mRNA translation and gefitinib resistance in cancer. Cell Reports. 2023 Jul 25;42(7):112810.
3. Wang Z, Yu P, Zou Y, Ma J, Han H, Wei W, Yang C, Zheng S, Guo S, Wang J, Liu L, Lin S. METTL1/WDR4-mediated tRNA m7G modification and mRNA translation control promote oncogenesis and doxorubicin resistance. Oncogene. 2023 Jun; 42(23):1900-1912.
4. Liu H*, Zeng X*, Ren X*, Zhang Y*, Huang M*, Tan L, Dai Z, Lai J, Xie W, Chen Z, Peng S, Xu L, Chen S, Shen S#, Kuang M#, Lin S#. Targeting tumor-intrinsic N7-methylguanosine tRNA modification inhibits MDSC recruitment and improves anti-PD-1 efficacy. Gut. 2023 Aug;72(8):1555-1567.
5. Peng H*, Chen B*, Wei W*, Guo S*, Han H, Yang C, Ma J, Wang L, Peng S#, Kuang M#, Lin S#. N6-methyladenosine (m6A) in 18S rRNA promotes fatty acid metabolism and oncogenic transformation. Nature Metabolism. 2022 Aug;4(8):1041-1054.
6. Han H*, Zheng S*, Lin S. N7-methylguanosine (m7G) tRNA modification: a novel autophagy modulator in cancer. Autophagy. 2022 May 23:1-3. (Commentary)
7. Han H*, Yang C*, Ma J*, Zhang S*, Zheng S*, Ling R, Sun K, Guo S, Huang B, Liang Y, Wang L, Chen S, Wang Z, Wei W, Huang Y, Peng H, Jiang YZ, Choe J, Lin S. N7-methylguanosine tRNA modification promotes esophageal squamous cell carcinoma tumorigenesis via the RPTOR/ULK1/autophagy axis. Nature Communications. 2022 Mar 18;13(1):1478.
8. Su T, Cheng F, Qi J, Zhang Y, Zhou S, Mei L, Fu S, Zhang F, Lin S#, Zhu G#. Responsive Multivesicular Polymeric Nanovaccines that Codeliver STING Agonists and Neoantigens for Combination Tumor Immunotherapy. Advanced Science. 2022 Jun 16;e2201895.
9. Zheng S, Han H, Lin S. N6-methyladenosine (m6A) RNA modification in tumor immunity. Cancer Biology & Medicine. 2022 Mar 8;19(4):385-97. (Review)
10. Wang L, Liang Y, Lin R, Xiong Q, Yu P, Ma Y, Cheng M, Han H, Wang X, Wang G, Liang F, Pei Z, Chen D, Yuan Q#, Jiang YZ#, Lin S#. Mettl5 mediated 18S rRNA N6-methyladenosine (m6A) modification controls stem cell fate determination and neural function. Genes Diseases. 2022 Jan, 9(1): 268-274.
11. Yang C, Han H, Lin S. RNA epitranscriptomics: A promising new avenue for cancer therapy. Molecular Therapy. 2022 Jan 5;30(1):2-3. (Editorial)
12. Chen Z*, Zhu W*, Zhu S*, Sun K, Liao J, Liu H, Dai Z, Han H, Ren X, Yang Q, Zheng S, Peng B, Peng S, Kuang M#, Lin S#. METTL1 promotes hepatocarcinogenesis via m7G tRNA modification-dependent translation control. Clinical and Translational Medicine. 2021 Dec;11(12):e661.
13. Dai Z*, Liu H*, Liao J*, Huang C*, Ren X*, Zhu W, Zhu S, Peng B, Li S, Lai J, Liang L, Xu L, Peng S, Lin S#, Kuang M#. N7-methylguanosine tRNA modification enhances oncogenic mRNA translation and promotes intrahepatic cholangiocarcinoma progression. Molecular Cell. 2021 Aug 19;81(16):3339-3355.
14. Ma J*, Han H*, Huang Y*, Yang C, Zheng S, Cai T, Bi J, Huang X, Liu R, Huang L, Luo Y#, Li W#, Lin S#. METTL1/WDR4 mediated N7-methylguanosine (m7G) tRNA modifications and m7G codon usage promote mRNA translation and lung cancer progression. Molecular Therapy. 2021 Aug 8:S1525- 0016(21)00399-3.
15. Han H*, Yang C*, Zhang S*, Cheng M*, Guo S, Zhu Y, Ma Y, Liang Y, Wang L, Zheng S, Wang Z, Chen D#, Jiang YZ#, Lin S#. METTL3 mediated m6A mRNA modification promotes esophageal cancer initiation and progression via Notch signaling pathway. Molecular Therapy-Nucleic Acids. 2021 Jul 21; 26:333-346.
16. Lin S#, Liu Q, Jiang YZ, Gregory RI#. Nucleotide resolution profiling of m7G tRNA modification by TRAC-Seq. Nature Protocols. 2019 Nov; 14: 3220–3242.
17. Wu Y*, Xie L*, Wang M, Xiong Q, Guo Y, Liang Y, Li J, Sheng R, Deng P, Wang Y, Zheng R, Jiang Y, Ye L, Chen Q, Zhou X#, Lin S#, Quan Y#. Mettl3-mediated m6A RNA methylation regulates the fate of bone marrow mesenchymal stem cells and osteoporosis. Nature Communications 2018. 9:4772.
18. Choe J*, Lin S*, Zhang W, Liu Q, Wang L, Ramirez-Moya J, Du P, Kim W, Tang S, Sliz P, Santisteban P, George RE, Richards WG, Wong KK, Locker N, Slack FJ, Gregory RI. mRNA circularization by METTL3-eIF3h enhances translation and promotes oncogenesis. Nature 2018 Sep;561(7724):556-560
19. Lin S*, Liu Q*, Lelyveld VS, Choe J, Szostak JW, Gregory RI. The Mettl1/Wdr4 mediated m7G tRNA methylome is required for normal mRNA translation and embryonic stem cell self-renewal and differentiation. Molecular Cell. 2018 Jul 19;71(2):244-255.
20. Lin S*, Choe J*, Du P, Triboulet R, Gregory RI. The m6A Methyltransferase METTL3 Promotes Translation in Human Cancer Cells. Molecular Cell. 2016 May 5; 62(3):335-345. Highlighted in Mol Cell. 2016 May 5; 62(3):323-324 and Cancer Discov. 2016 Jun; 6(6):572.
21. Lin S, Gregory RI. MicroRNA biogenesis in cancers. Nature Reviews Cancer. 2015 Jun; 15(6):321-33.
22. Lin S, Gregory RI. Methyl-transferases modulate RNAs stability in embryonic stem cells. Nature Cell Biology. 2014 Feb;16(2):129-31. (News and Views).
23. Su T*, Zhang Y*, Valerie K, Wang XY, Lin S#, Zhu G#. STING activation in cancer immunotherapy. Theranostics. 2019 Oct 15;9(25):7759-7771.
24. Yang F *, Jin H*, Que B*, Chao Y*, Zhang H, Ying X, Zhou Z, Yuan Z, Su J, Wu B, Zhang W, Qi D, Chen D, Min W#, Lin S#, Ji W#. Dynamic m6A mRNA methylation reveals the role of METTL3-m6A-CDCP1 signaling axis in chemical carcinogenesis. Oncogene 2019 Jun;38(24):4755-4772.
25. Lin S, Gregory RI. Identification of small molecule inhibitors of Zcchc11 TUTase activity. RNA Biology. 2015;12(8):792-800.
26. Lin S*, Tian L*, Shen H*, et.al. DDX5 is a positive regulator of oncogenic NOTCH1 signaling in T cell acute lymphoblastic leukemia. Oncogene. 2013 Oct;32(40):4845-53.
27. Lin S, Shen H, Jin B, et.al. Blockade of Notch Signaling in Muscle Stem Cells Causes Muscular Dystrophic Phenotype and Impaired Muscle Regeneration. Stem Cells. 2013 Apr;31(4):823-8.
28. Lin S, Shen H, Li JL, et.al. Proteomic and functional analyses reveal the chromatin reader SFMBT1's role in regulating epigenetic silencing and the myogenic gene program. Journal of Biological Chemistry. 2013 Mar 1;288(9):6238-47.
