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成果及论文

  

研究论文:

2024  

33      Xianghua Zhong, Li Luo, Jiyuan Wu, Weirun Li, Xinyang Liu, Tenghui Ye, Zhenhua Li, Peng Shi,*  Adhesion-assisted antioxidant-engineered mesenchymal stromal cells for synergistic therapy of myocardial infarction in rats and pigs. In preparation.

32       Yuheng Lv, Yicun Li, Qin Fu, Peng Shi,* Controllable Multivalent LYTACs Enhance Targeted Protein Degradation. In preparation.


2023  

31      Han Li,  Haixia Sun,  Yuyu Liu, Binghan Yuan,  Jingyuan Hu,  Yunzhe Jiang,  Qingkai Li,  Suilan Cao,  Hong Liu,  Baiquan Xiao, Peng Shi,*   Xiangliang Yang,*   Shaobin Wang*  and  Yongsheng Zhao*, Toxicology and safety research of poly(N-isopropylacrylamide)-based thermosensitive nanogels. Environ. Sci.: Nano, 2023.

30        Yuheng Lv, Qin Fu, Yi Xu, Peng Shi,* Sequentially-Activated Antibodies Based on Programmable DNA Tags for Rapid Multiplexed Protein Imaging. Small, 2023, 2306638.

29        Xianghua Zhong, Qin Fu, Xinchao Liu, Peng Shi,* Real-time tracking of the intracellular delivery of a 2D nanosystem using a progressively activatable fluorescence platform for cancer diagnosis. Chem Commun, 2023, 59, 10161-10164.

28        Tenghui Ye, Xi Liu, Xianghua Zhong, Ran Yan, Peng Shi,* Nongenetic surface engineering of mesenchymal stromal cells with polyvalent antibodies to enhance targeting efficiency. Nature Communications. 2023, 14, 5806.


2022  

27        Zhuo Li, Haixing Wang, Kunyu Zhang, Boguang Yang, Xian Xie, Zhengmeng Yang, Lingchi Kong, Peng Shi, Yuan Zhang, Yi-Ping Ho, Zhi-Yong Zhang, Gang Li, Liming Bian, Bisphosphonate-based hydrogel mediates biomimetic negative feedback regulation of osteoclastic activity to promote bone regeneration. Bioactive materials. 2022, 13, 9-22.

26        Brandon Davis, Peng Shi, Erin Gaddes, Jinping Lai, Yong Wang, Bidirectional Supramolecular Display and Signal Amplification on the Surface of Living Cells. Biomacromolecules. 2022, 23(3), 1403-1412.

25        Xuelin Wang, Connie Wen, Brandon Davis, Peng Shi, Lidya Abune, Kyungsene Lee, Cheng Dong, Yong Wang, Synthetic DNA for Cell Surface Engineering: Experimental Comparison between Click Conjugation and Lipid Insertion in Terms of Cell Viability, Engineering Efficiency, and Displaying Stability. ACS Applied Materials & Interfaces. 2022, 14(3), 3900-3909.


2021

24        Pengchao Zhao, Xianfeng Xia, Xiayi Xu, Kevin Kai Chung Leung, Aliza Rai, Yingrui Deng, Boguang Yang, Huasheng Lai, Xin Peng, Peng Shi, Honglu Zhang, Philip Wai Yan Chiu*, Liming Bian*, Nanoparticle-assembled bioadhesive coacervate coating with prolonged gastrointestinal retention for inflammatory bowel disease therapy. Nature Communications. 2021, 12, 7162.

23        Zhuo Li, Haixing Wang, Kunyu Zhang, Boguang Yang, Xian Xie, Zhengmeng Yang, Lingchi Kong, Peng Shi, Yuan Zhang, Yi-Ping Ho, Zhi-Yong Zhang*, Gang Li*, Liming Bian*, Bisphosphonate-based hydrogel mediates biomimetic negative feedback regulation of osteoclastic activity to promote bone regeneration. Bioactive Materials. 2021.

22.       Junsheng Zhang, Siu Hong Dexter Wong, Xin Wu, Hai Lei, Meng Qin, Peng Shi, Wei Wang*, Liming Bian*, Yi Cao*. Engineering Photoresponsive Ligand Tethers for Mechanical Regulation of Stem Cells. Adv. Mater. 2021, 2105765.

21.       Peng Shi, Yong Wang*, Synthetic DNA for Cell Surface Engineering. Angew.Chem. Int. Ed. 2021, 60, 11580-11591.


2020

20.       Nan Zhao, James Coyne, Lidya Abune, Peng Shi, Xiaojun Lance Lian, Ge Zhang, and Yong Wang*, Exogenous Signaling Molecules Released from Aptamer-Functionalized Hydrogels Promote the Survival of Mesenchymal Stem Cell Spheroids. ACS Appl. Mater. Interfaces 2020, 12, 22, 24599-24610.

19.       Peng Shi, Xuelin Wang, Brandon Davis, James Coyne, Cheng Dong, Joshua Reynolds, Yong Wang*, In situ synthesis of aptamer-based polyvalent antibody mimic on the cell surface for enhanced immune-cancer cell interactions. Angew.Chem. Int. Ed. 2020, 59, 11892-11897 (IF= 12.257)


2019  

18.       Peng Shi, Nan Zhao, James Coyne, Yong Wang*, DNA-templated Synthesis of Biomimetic Cell Wall on Mammalian Cells for Nanoencapsulation and Protection of Mammalian cells. Nat. Commun. 2019, 10, 2223. (IF= 11.878) ( NanowerkPhys.orgNewswise等亮点报道)

17.       Nan Zhao, Akiho Suzuki, Xiaolong Zhang, Peng Shi, Lidya Abune, James Coyne, Huizhen Jia, Na Xiong, Ge Zhang, Yong Wang*, Dual Aptamer-functionalized In Situ Injectable Fibrin Hydrogel for Promotion of Angiogenesis via Co-delivery of VEGF and PDGF-BB. ACS Appl. Mater. Interfaces 2019, 11, 18123-18132.

16.       Nan Zhao, James Coyne, Ming Xu, Xiaolong Zhang, Akiho Suzuki, Peng Shi, Jinping Lai, Guo-Hua Fong, Na Xiong and Yong Wang*, Assembly of Bifunctional Aptamer-Fibrinogen Macromer for VEGF Delivery and Skin Wound Healing. Chem. Mater. 2019, 31, 1006-1015.


2018  

15.       Peng Shi, Nan Zhao, Jinping Lai, James Coyne, Erin Gaddes, Yong Wang*, Polyvalent Display of Biomolecules on Live Cells. Angew.Chem. Int. Ed. 2018, 57, 6800 –6804. (IF= 12.257) (封面文章,被 ChemistyViews报道“Viewing Biomolecules on Cellular Surfaces)


2017  

14.       Jiasi Wang, Peng Shi, Kai Dong, Zhengqing Yan, Jinsong Ren and Xiaogang Qu*, Regulation of cell fate by near infrared-responsive telomerase activity. Mater. Today. 2017, 20(8), 406-412.

13.       Pinliang Jiang, Shihui Li, Jinping Lai, Hong Zheng, Changjian Lin, Peng Shi, Yong Wang*, Nanoparticle-Programmed Surface for Drug Release and Cell Regulation via Reversible Hybridization Reaction. ACS Appl. Mater. Interfaces 2017, 9, 4467-4474.

12.    Peng Shi, Enguo Ju, Jiasi Wang, Zhengqing Yan, Jinsong Ren, and Xiaogang Qu*, Host–Guest Recognition on Photo-responsive Cell Surfaces Directs Cell–Cell Contacts. Mater. Today. 2017, 20(1), 16-21. (IF= 24.372)


2016  

11.    Peng Shi, Enguo Ju, Zhengqing Yan, Nan Gao, Jiasi Wang, Jianwen Hou, Yan Zhang, Jinsong Ren, and Xiaogang Qu*, Spatiotemporal Control of Cell–Cell Reversible Interactions Using Molecular Engineering. Nat. Commun. 2016, 7, 13088. (IF= 11.878)


2015  

10.    Zhengqing Yan, Peng Shi, Jinsong Ren and Xiaogang Qu*, A “Sense-and-Treat” Hydrogel Used for Treatment of Bacterial Infection on the Solid Matrix. Small, 2015, 11,5540.

9.    Can Xu, Peng Shi, Meng Li, Jinsong Ren and Xiaogang Qu*, A cytotoxic amyloid oligomer self-triggered and NIR-enhanced amyloidosis therapeutic system. Nano Res., 2015, 8, 2431.

8.    Wei Bing. Zhaowei Chen. Hanjun Sun. Peng Shi. Gao, N. Jinsong Ren. Xiaogang Qu*. Visible-light-driven enhanced antibacterial and biofilm elimination activity of graphitic carbon nitride by embedded Ag nanoparticles. Nano Res., 2015, 8, 1648-1658.


2014  

7.    Zhenzhen Wang, Zhaowei Chen, Zhen Liu, Peng Shi, Kai Dong, Enguo Ju, Jinsong Ren and Xiaogang Qu*, A multi-stimuli responsive gold nanocage-hyaluronic platform for targeted photothermal and chemotherapy. Biomaterials, 2014, 35, 9678-9688.

6.    Peng Shi, Zhen Liu, Kai Dong, Enguo Ju, Jinsong Ren, Yingda Du, Zhengqiang Li, and Xiaogang Qu*, A Smart “Sense-Act-Treat” System: Combining a Ratiometric pH Sensor with a Near Infrared Therapeutic Gold Nanocage. Adv. Mater. 2014, 26, 6635-6641. (IF= 25.809) ( MaterialsViews报道“A Sense-Act-Treat System for Chemotherapy)

5.    Konggang Qu, Peng Shi, Jinsong Ren and Xiaogang Qu*, Nanocomposite Incorporating V2O5 Nanowires and Gold Nanoparticles for Mimicking an Enzyme Cascade Reaction and Its Application in the Detection of Biomolecules. Chem.-Eur. J., 2014, 20, 7501-7506.

4.    Peng Shi, Enguo Ju, Jinsong Ren and Xiaogang Qu*, Near-Infrared Light-Encoded Orthogonally Triggered and Logical Intracellular Release Using Gold Nanocage@Smart Polymer Shell. Adv. Funct. Mater. 2014, 24, 826–834. (IF= 15.621)


2013  

3.    Peng Shi, Meng Li, Jinsong Ren and Xiaogang Qu*, Gold Nanocage-Based Dual Responsive “Caged Metal Chelator” Release System: Noninvasive Remote Control with Near Infrared for Potential Treatment of Alzheimer’s Disease. Adv. Funct. Mater. 2013, 23, 5412–5419. (IF= 15.621) (封面文章,被 MaterialsViewsMaterialsViewsChina报道“Remote Controlled Drug Delivery)

2.    Meng Li, Peng Shi, Can Xu, Jinsong Ren and Xiaogang Qu*, Cerium oxide caged metal chelator: anti-aggregation and anti-oxidation integrated H2O2-responsive controlled drug release for potential Alzheimer's disease treatment. Chem. Sci., 2013, 4, 2536-2542.


2012  

1.    Peng Shi, Konggang Qu, Jiasi Wang, Meng Li, Jinsong Ren and Xiaogang Qu*, pH-responsive NIR enhanced drug release from gold nanocages possesses high potency against cancer cells. Chem. Commun. 2012, 48, 7640–7642. (IF= 6.164)

 

专利申请:

1.       Yong Wang, Peng Shi. Synthesis of Biomimetic Cell Wall Structure. US Provisional Patent application No. 62/808,358.

2.       Yong Wang, Peng Shi. Synthesis of Biomimetic Cell Wall Structure. PCT Serial NO. PCT/US2020/019312.

3.       Yong Wang, Brandon Davis, Peng Shi. Biodegradable DNA-alginate conjugate for reversible protein and cell labeling and imaging. US Provisional Patent application No. 63/010,146.

4.       石鹏、叶腾辉、钟祥华、晏然、刘茜,一种基于蛋白多聚体的间充质干细胞工程化改造方法及其应用,申请日:2023-01-03,申请号:ZL202310002208.6.

5.       石鹏、钟祥华,一种基于聚多巴胺和VCAM1抗体的干细胞工程化改造方法及其应用,申请日:2024-03-13,申请号:ZL202410286475.5.

6.       石鹏、刘鑫超,一种用于间充质干细胞封装的自组装聚合物材料及其制备方法与应用,申请日:2023-10-23,申请号:ZL202311379233.2.