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成果及论文

工作业绩:

临床方向:成人重建外科(关节置换、关节重建成形)和运动医学(关节镜及其康复)。长期接受蒋青教授关节外科及运动医学临床训练,美国匹兹堡大学Freddie Fu教授指导运动医学技术、Lawrence S. Crossett教授带教关节置换及翻修手术,掌握运动医学及关节外科疾病的诊治,同时掌握关节镜下治疗交叉韧带损伤、半月板成形等微创手术,以及初次髋膝关节置换。每年完成关节置换约300例,运动医学相关手术200例。并开展了多项临床随机对照试验。


科研业绩:

迄今共发表Web of Science收录论文103篇,包括Nat Med30.641)、Nat Genet25.455)、Ann Rheum Dis14.299)、J Clin Invest 12.282)、Hum Mol Genet4.544等国际顶级期刊,涉及包括遗传学、再生医学、生物医学工程等国内外热门领域。截至今年2月底,所发表SCI论文共被引用1812,其中3篇文章单篇最高引用频次超过100(分别为287次、123次和118次),单篇每年平均最高被引22.08次,H指数22;近5年内所有论文共被引用1016H指数18获授权中国专利8项。

5年(2015年至今)共发表Web of Science收录论文53篇,其中通讯(含共同通讯,下同)作者论文12篇,唯一第一作者论文4篇,包括ACS NanoIF=13.903)、Angew Chem Int Ed Engl12.257)、Science AdvancesIF=12.804),Nano research8.515)、 Arthritis Res Ther4.148)、Clin Genet4.104)、Ann Transl Med3.689等国际著名期刊;

主持NSFC优秀青年项目1,专项项目1项,面上项目2项,科技部国家重点研发计划子课题1项;主持江苏省重点人才项目1项,江苏省科技厅社会发展项目1项,江苏省人事厅六大人才高峰A类项目。


科研项目及人才计划项目情况:


国家自然科学基金

  国家自然科学基金专项项目,代谢相关性小型猪骨质疏松动物模型的建立,2020-202376万,在研,主持

  国家自然科学基金优秀青年基金,运动医学,2017-2019130万,在研,主持。

  国家自然科学基金面上项目,缓释BIO透明质酸凝胶修复软骨缺损的研究,2018-202155万,在研,主持

  国家自然科学基金面上项目,紫外聚合缓释Kartogenin PLGA纳米颗粒/水凝胶复合支架修复软骨缺损,2016-201957万,在研,主持。

  科技部重点专项课题组长:软骨损伤修复 256万,在研

  国家自然科学基金青年基金,Asporin基因在发育性髋关节发育不良发病作用,2011-201422万,已结题,主持。


省市级基金及人才项目

  江苏省科技厅社会发展项目,缓释小分子药物Kortogenin治疗软骨损伤性疾病,2016-201940万,结题,主持。

  强卫工程江苏省重点人才,2016-202050万,在研,主持

  南京市卫生局杰出青年基金,关节腔注射Kartogenin修复软骨缺损, 2013-201650万,结题,主持。

  江苏省人事厅六大人才高峰-高层次人才A类,软骨修复,2019-202215万,在研,主持。

  江苏省人事厅六大人才高峰-高层次人才C类,缓释小分子有机化合物BIO的多肽水凝胶修复软骨缺损,2016-20194万,结题,主持。

  江苏省人事厅六大人才高峰项目D类,软骨再生医学研究,2012-20153万,已结题,主持。

  中央高校专项基金,南京大学2012年苗圃项目,2012/01-2012/123万,已结题,主持。


奖励情况:

国内:

2009年江苏省科学技术进步奖二等奖,排名第二

2009年南京市科技进步奖一等奖,排名第二

2010年江苏省医学奖三等奖,排名第二

2012年南京市新技术引进奖一等奖

2013年南京市科技进步奖二等奖,排名第二

2014教育部自然科学奖二等奖,排名第二

201611江苏青年五四奖章

2016南京青年五四奖章

2018年江苏省科技进步奖 一等奖 排名第三

2019年江苏省医学奖。   二等奖 排名第一

国际:

     2010  OARSI Travel Award 

 2014  OARSI Travel Award 

 

部分发表文章

 

1.  Dongquan Shi, Nicholas D. Clement, Rameah Bhonde, Shiro Ikegawa, Vasco V. Mascarenhas, Berardo Di Matteo, Pier Francesco Indelli, Nikolaos Kourkoumelis, E. Carlos Rodríguez-Merchán, Mohsen Sheykhhasan, Freddie H. Fu, Marco Aurélio Vaz, Jian Kong, Boris Gabin Kingue Azantsa, Chuan Ye, Farzin Halabchi, Stephen M. Cornish, Leslie R. M. Hausmann, André Luiz Siqueira Campos, Carlos César Lopes de Jesus, Christian Jorgensen, Elena M. Ilieva, Weiguo Wang, Laura Villarreal Martínez, Hyochol Ahn, Ivan V. Shirinsky, Corjena Cheung, Gunnar Knutsen, Wolf Petersen, Nancy E. Lane, Hong Cai, Wei Xu, Jian Wu, Jun Lu, Yingze Zhang, Qing Jiang. Society for translational medicine-expert consensus on the treatment of osteoarthritis. Annals of Joint   2019; 4: 49.

 

2.     Xingquan XuPeilai LiuZhenfeng YuanDawei WangQunshan LuZhe ZhangQing JiangDongquan Shi. Comparison of a Novel Handheld Accelerometer-Based Navigation System and Conventional Instrument for Performing Distal Femoral Resection in Total Knee Arthroplasty: A Randomized Controlled Trial. Ann Transl Med, 20197 (22), 659

 

3.     Wan MMXu TTChi BWang MHuang YWang QLi TYan WQChen HXu PMao CZhao BShen JXu HShi DQ. A Safe and Efficient Strategy for the Rapid Elimination of Blood Lead In Vivo Based on a Capture-Fix-Separate Mechanism. Angew Chem Int Ed Engl. 2019 Jul 29;58(31):10582-10586.

 

4.     Yan W, Xu X, Xu Q, Yan W, Sun Z, Jiang Q, Shi D. Femoral and tibial torsion measurements based on EOS imaging compared to 3D CT reconstruction measurements. Ann Transl Med. 2019 Sep;7(18):460. doi: 10.21037/atm.2019.08.49.

 

5.     Jiang T, Yao Y, Xu X, Song K, Pan P, Chen D, Xu Z, Dai J, Qin J, Shi D, Jiang Q. Prevalence and risk factors of preoperative deep vein thrombosis in patients with end-stage knee osteoarthritis.Ann Vasc Surg. 2019 Oct 15. pii: S0890-5096(19)30777-0. doi: 10.1016/j.avsg.2019.08.089.

 

6.     Xu X, Wang R, Sun Z, Wu R, Yan W, Jiang Q, Shi D.Trehalose enhances bone fracture healing in a rat sleep deprivation model.Ann Transl Med. 2019 Jul;7(14):297. doi: 10.21037/atm.2019.05.73.

 

7.     Li J, Chen G, Xu X, Abdou P, Jiang Q, Shi D, Gu Z.Advances of injectable hydrogel-based scaffolds for cartilage regeneration.Regen Biomater. 2019 Jun;6(3):129-140

 

8.     Li L, Yu F, Zheng L, Wang R, Yan W, Wang Z, Xu J, Wu J, Shi D, Zhu L, Wang X, Jiang Q.Natural hydrogels for cartilage regeneration: Modification, preparation and application.J Orthop Translat. 2018 Oct 14;17:26-41

 

9.     Wang R, Xu X, Li Y, Li J, Yao C, Wu R, Jiang Q, Shi D. A C-Met chemical inhibitor promotes fracture healing through interacting with osteogenic differentiation via the mTORC1 pathway.Exp Cell Res. 2019 Aug 1;381(1):50-56

 

10.   Yan W, Hao Z, Tang S, Dai J, Zheng L, Yu P, Yan W, Han X, Xu X, Shi D, Ikegawa S, Teng H, Jiang Q. A genome-wide association study identifies new genes associated with developmental dysplasia of the hip.Clin Genet. 2019 Mar;95(3):345-355.

 

11.   Qin J, Xu Z, Dai J, Chen D, Xu X, Song K, Shi D, Jiang Q. New technique: practical procedure of robotic arm-assisted (MAKO) total hip arthroplasty. Ann Transl Med. 2018 Sep;6(18):364.

 

12.   Xu X, Yao C, Wu R, Yan W, Yao Y, Song K, Jiang Q, Shi D. Prevalence of patellofemoral pain and knee pain in the general population of Chinese young adults: a community-based questionnaire survey.BMC Musculoskelet Disord. 2018 May 24;19(1):165. 

 

13.   Yao C, Zhang Z, Yao Y, Xu X, Jiang Q, Shi D. Predictive value of neutrophil to lymphocyte ratio and platelet to lymphocyte ratio for acute deep vein thrombosis after total joint arthroplasty: a retrospective study.J Orthop Surg Res. 2018 Feb 27;13(1):40. 

 

14.   Yao C, Xu X, Zhou S, Song X, Shi D, Jiang Q. Total knee arthroplasty conversion after a failed lateral closing wedge high tibial osteotomy with knee hyperextension and secondary ankle degeneration: A case report.Medicine (Baltimore). 2017 Jul;96(29):e7473. 

 

15.   Xu R, Shi D, Ge W, Jiang Q. Quantitative efficacy of topical administration of tranexamic acid on postoperative bleeding in total knee arthroplasty.Br J Clin Pharmacol. 2017 Nov;83(11):2485-2493. 

 

16.   Yao C, Xu X, Zhou S, Song X, Shi D, Jiang Q. Total knee arthroplasty conversion after a failed lateral closing wedge high tibial osteotomy with knee hyperextension and secondary ankle degeneration: A case report.Medicine (Baltimore). 2017 Jul;96(29):e7473. 

 

17.   Xu X, Shi D, Liu Y, Yao Y, Dai J, Xu Z, Chen D, Teng H, Jiang Q. In vivo repair of full-thickness cartilage defect with human iPSC-derived mesenchymal progenitor cells in a rabbit model. Exp Ther Med. 2017 Jul;14(1):239-245

 

18.   Yan W, Dai J, Xu Z, Shi D, Chen D, Xu X, Song K, Yao Y, Li L, Ikegawa S, Teng H, Jiang Q.Novel WISP3 mutations causing progressive pseudorheumatoid dysplasia in two Chinese families. Hum Genome Var. 2016 Dec 8;3:16041. doi: 10.1038/hgv.2016.41.

 

19.    Zhang H, Mao P, Wang C, Chen D, Xu Z, Shi D, Dai J, Yao Y, Jiang Q.Incidence and risk factors of deep vein thrombosis (DVT) after total hip or knee arthroplasty: a retrospective study with routinely applied venography.Blood Coagul Fibrinolysis. 2016 Jul 6. [Epub ahead of print]

 

20.   Song K, Rong Z, Yang X, Yao Y, Shen Y, Shi D, Xu Z, Chen D, Zheng M, Jiang Q. Early Pulmonary Complications following Total Knee Arthroplasty under General Anesthesia: A Prospective Cohort Study Using CT Scan. Biomed Res Int. 2016;2016:4062043. 

 

21.   Shi D, Xu X, Ye Y, Song K, Cheng Y, Di J, Hu Q, Li J, Ju H, Jiang Q, Gu Z.Photo-Cross-Linked Scaffold with Kartogenin-Encapsulated Nanoparticles for Cartilage Regeneration.ACS Nano. 2016 Jan 26;10(1):1292-9.

 

22.   Shi D, Dai J, Xu Z, Chen D, Jiang Q. Update on basic and clinical aspects of osteoarthritis.Ann Transl Med. 2015 Jun;3(10):142. 

 

 

23.   Shi D, Xu X, Guo A, Dai J, Xu Z, Chen D, Jiang Q et al. Bone Cement Solidifiliation Influence the Limb Alignment and Gap Balance during TKA. Biomed Res Int. 2015;2015:109402. doi: 10.1155/2015/109402. Epub 2015 Jan 22.

 

24.   Xu X, Shi D, Shen Y, Xu Z, Dai J, Chen D, Teng H, Jiang Q. Full-thickness cartilage defects are repaired via a microfracture technique and intra-articular injection of the small molecule compound kartogenin. Arthritis Res Ther. 2015 Feb 2;17(1):20. [Epub ahead of print]

 

25.   Shi D, Xu X, Xu Z, Nakamura T, Pang Y, Yao C, Wang F, Chen D, Dai J, Jiang Q. P-selectin: an unpredicted factor for deep vein thrombosis after total hip arthroplasty. Biomed Res Int. 2014;2014:783967. 

 

26.   Shi D, Xu X, Song K, Xu Z, Dai J, Chen D, Jiang Q. Comparison of Venous Thromboembolism after Total Hip Arthroplasty between Ankylosing Spondylitis and Osteoarthritis. Biomed Res Int. 2014;2014:712895

 

27.   Dongquan Shi, Wei Sun, Xingquan Xu, Zheng Hao, Jin Dai, Zhihong Xu, Dongyang Chen, Huajian Teng, and Qing Jiang. A Replication Study for the Association of rs726252 in PAPPA2 with Developmental Dysplasia of the Hip in Chinese Han Population. BioMed Research International 2014: 979520

 

 

28.   Wang K, Shi D, SUN Li-sheng, JIANG Xu, LÜ Yan-yun, DAI Jin, CHEN Dong-yang, XU Zhi-hong and JIANG Qing. Association of estrogen receptor alpha gene polymorphisms with bone mineral density: a meta-analysis. Chinese Medical Journal 2012;125(14):2589-2597

 

29.   Song YQ, Karasugi T, Cheung KM, Chiba K, Ho DW, Miyake A, Kao PY, Sze KL, Yee A, Takahashi A, Kawaguchi Y, Mikami Y, Matsumoto M, Togawa D, Kanayama M, Shi D, Dai J, Jiang Q, Wu C, Tian W, Wang N, Leong JC, Luk KD, Yip SP, Cherny SS, Wang J, Mundlos S, Kelempisioti A, Eskola PJ, Männikkö M, Mäkelä P, Karppinen J, Järvelin MR, O'Reilly PF, Kubo M, Kimura T, Kubo T, Toyama Y, Mizuta H, Cheah KS, Tsunoda T, Sham PC, Ikegawa S, Chan D. Lumbar disc degeneration is linked to a carbohydrate sulfotransferase 3 variant.J Clin Invest. 2013 Nov 1;123(11):4909-17.

 

30.   Qin J, Xu Z, Shi D, Chen D, Dai J, Teng H, Jiang Q.Deep vein thrombosis after total hip arthroplasty and total knee arthroplasty in patients with previous ischemic stroke.Int J Low Extrem Wounds. 2013 Dec;12(4):316-9.

 

31.   Xu Z, Shi D, Zhang C, Chen D, Dai J, Teng H, Jiang Q.Postoperative plasma D-dimer value for predicting deep venous thrombosis following hip arthroplasty with nadroparin prophylaxis.Hip Int. 2013 Jul-Aug;23(4):411-6. 

 

 

32.   Qin J, Dai J, Xu Z, Chen D, Qin J, Shi D, Teng H, Jiang Q.Genetic polymorphism of NOS3 with susceptibility to deep vein thrombosis after orthopedic surgery: a case-control study in Chinese Han population.PLoS One. 2013 Jul 26;8(7):e70033.

 

33.   Ye S, Dongyang C, Zhihong X, Dongquan S, Jin D, Jianghui Q, Jizhen Q, Pu Y, Huacheng H, Wei S, Qing J.The incidence of deep venous thrombosis after arthroscopically assisted anterior cruciate ligament reconstruction.Arthroscopy. 2013 Apr;29(4):742-7.

 

 

34.   Wang C, Yang F, Xu Z, Shi D, Chen D, Dai J, Gu N, Jiang Q.Intravenous release of NO from lipidic microbubbles accelerates deep vein thrombosis resolution in a rat model.Thromb Res. 2013 Jan;131(1):e31-8

 

35.   Xu Z, Chen D, Shi D, Jiang Q.Case report: Osteochondral avulsion fracture of the posteromedial bundle of the PCL in knee hyperflexion.Clin Orthop Relat Res. 2012 Dec;470(12):3616-23..

36.   Wang K, Shi D, SUN Li-sheng, JIANG Xu, LÜ Yan-yun, DAI Jin, CHEN Dong-yang, XU Zhi-hong and JIANG Qing. Association of estrogen receptor alpha gene polymorphisms with bone mineral density: a meta-analysis. Chinese Medical Journal 2012;125(14):2589-2597

 

37.   Shi D, Dai J, Ikegawa S, Jiang Q. Genetic study on developmental dysplasia of the hip. Eur J Clin Invest. 2012 Apr 24. doi: 10.1111/j.1365-2362.2012.02682.x. [Epub ahead of print]

 

38.   Hou H, Ge Z, Ying P, Dai J, Shi D, Xu Z, Chen D, Jiang Q. Biomarkers of deep venous thrombosis. J Thromb Thrombolysis. 2012 Apr 12. [Epub ahead of print]

 

 

39.   Nakajima M, Shi D, Dai J, Tsezou A, Zheng M, Norman PE, Chou CH, Lee MT, Hwang JY, Kim DH, Takahashi A, Ikegawa S, Jiang Q.A large-scale replication study for the association of rs17039192 in HIF-2α with knee osteoarthritis.J Orthop Res. 2012 Jan 13. doi: 10.1002/jor.22063. [Epub ahead of print] (Co-first author)

 

40.   Shi D, Dai J, Zhu P, Qin J, Zhu L, Zhu H, Zhao B, Qiu X, Xu Z, Chen D, Yi L, Ikegawa S, Jiang Q. Association of the D repeat polymorphism in the ASPN gene with developmental dysplasia of the hip: a case-control study in Han Chinese. Arthritis Res Ther. 2011 Feb 17;13(1):R27. [Epub ahead of print]

IF=4.04

 

41.   Chen D, Xu Z, Shi D, Qiu X, Dai J, Yuan T, Weng W, Jiang Q. Clinical outcome of Zweymüller total hip arthroplasty for patients with high congenital hip dislocation. Hip Int. 2011 Jan-Mar;21(1):71-5.

IF=0.34

 

42.   Nakajima M, Shi D, Dai J, Tsezou A, Zheng MH, Paul EN, Takahashi A, Ikegawa S, Jiang Q. Replication studies in various ethnic populations do not support the previously reported association of rs17039192 in HIF-2 with knee osteoarthritis. Nature Medicine 2011 Jan;17(1):26-7;.  (Co-first author)

IF=27.136

43.   Shi D, Zheng Q, Chen D, Zhu L, Qin A, Fan J, Liao J, Xu Z, Lin Z, Normal P, Xu J, Nakamura T, Dai K, Zheng M, Jiang Q. Association of single-nucleotide polymorphisms in HLA class II/III region with knee osteoarthritis. Osteoarthritis Cartilage. 2010 Aug 4. [Epub ahead of print]IF=3.88

44.   Qin J, Shi D, Dai J, Zhu L, Tsezou A, Jiang Q. Association of the leptin gene with knee osteoarthritis susceptibility in a Han Chinese population: a case-control study. J Hum Genet. 2010 Jul 22. [Epub ahead of print] (Co-first author)

IF=2.27

45.    Zhu L, Shi D, Dai J, Qin J, Fan J, Wang Z, Qiu X, Xu Z, Chen D, Jiang Q. Lack of evidence for association between DVWA gene polymorphisms and developmental dysplasia of the hip in Chinese Han population. Rheumatol Int. 2010 Mar 18. [Epub ahead of print] (Co-first author)

IF=1.27 

46.   Fan J, Shi D, Dai J, Zhu L, Qin J, Shao Z, Qiu X, Xu Z, Chen D, Jiang Q. Genetic polymorphism of PITX1 in susceptibility to knee osteoarthritis in a Chinese Han population: a case-control study. Rheumatol Int. 2010 Jan 7. [Epub ahead of print] (Co-first author)

IF=1.27 

 

47.   Ji J, wang Z, Shi D, Gao X, Jiang Q. Pathologic changes of Achilles tendon in leptin-deficient mice. Rheumatol Int. 2010; 30(4):489-93.

IF=1.27 

 

48.   Evangelou E, Chapman K, Meulenbelt I, Karassa FB, Loughlin J, Carr A, Doherty M, Doherty S, Gómez-Reino JJ, Gonzalez A, Halldorsson BV, Hauksson VB, Hofman A, Hart DJ, Ikegawa S, Ingvarsson T, Jiang Q, Jonsdottir I, Jonsson H, Kerkhof HJ, Kloppenburg M, Lane NE, Li J, Lories RJ, van Meurs JB, Näkki A, Nevitt MC, Rodriguez-Lopez J, Shi D, Slagboom PE, Stefansson K, Tsezou A, Wallis GA, Watson CM, Spector TD, Uitterlinden AG, Valdes AM, Ioannidis JP.Large-scale analysis of association between GDF5 and FRZB variants and osteoarthritis of the hip, knee, and hand. Arthritis Rheum. 2009; 60(6):1710-21. 

IF=7.806

 

49.   Meulenbelt I, Chapman K, Dieguez-Gonzalez R, Shi D, Tsezou A, Dai J, Malizos KN, Kloppenburg M, Carr A, Nakajima M, van der Breggen R, Lakenberg N, Gomez-Reino JJ, Jiang Q, Ikegawa S, Gonzalez A, Loughlin J, Slagboom EP.Large replication study and meta-analyses of DVWA as an osteoarthritis susceptibility locus in European and Asian populations. Hum Mol Genet. 2009; 18(8):1518-23.

IF=7.806

50.   Haijian Ni Dongquan ShiJin DaiJianghui QinYong XuLunqing ZhuChen YaoZhenxing ShaoDongyang ChenZhihong XuLong YiShiro IkegawaQing Jiang. Genetic polymorphisms of interleukin-1β (−511C/T) and interleukin-1 receptor antagonist (86-bpVNTR) in susceptibility to knee osteoarthritis in a Chinese Han population. Rheumatol Int 2009; 29(11):1301-5. (Co-first author)

IF=1.27

 

51.   Dai J, Shi D, Zhu P, Qin J, Ni H, Xu Y, Yao C, Zhu L, Zhu H, Zhao B, Wei J, Liu B, Ikegawa S, Jiang Q, Ding Y. Association of a single nucleotide polymorphism in growth differentiate factor 5 with congenital dysplasia of the hip: a case-control study. Arthritis Res Ther. 2008;10(5):R126. 

IF=4.04

 

52.   Shi D, Ni H, Dai J, Qin J, Xu Y, Zhu L, Yao C, Shao Z, Chen D, Xu Z, Yi L, Ikegawa S, Jiang Q. Lack of association between the CALM1 core promoter polymorphism (-16C/T) and susceptibility to knee osteoarthritis in a Chinese Han population. BMC Med Genet. 2008; 9:91. 

IF=2.14

 

53.   Shi D, Nakamura T, Nakajima M, Dai J, Qin J, Ni H, Xu Y, Yao C, Wei J, Liu B, TXNDC3 with knee osteoarthritis susceptibility: two case-control studies in East Asian populations and a meta-analysis. Arthritis Res Ther. 2008;10(3):R54.

IF=4.04

 

54.   Jiang Q, Shi D, Nakajima M, Dai J, Wei J, Malizos KN, Qin J, Miyamoto Y, Kamatani N, Liu B, Tsezou A, Nakamura T, Ikegawa S. Lack of association of single nucleotide polymorphism in LRCH1 with knee osteoarthritis susceptibility. J Hum Genet. 2008;53(1):42-7. 

IF=2.275

 

55.   Shi D, Nakamura T, Dai J, Yi L, Qin J, Chen D, Xu Z, Wang Y, Ikegawa S, Jiang Q. Association of the aspartic acid-repeat polymorphism in the asporin gene with age at onset of knee osteoarthritis in Han Chinese population. J Hum Genet. 2007;52(8):664-7. 

IF=2.275

 

56.    Jiang Q, Shi D, Yi L, Ikegawa S, Wang Y, Nakamura T, Qiao D, Liu C, Dai J. Replication of the association of the aspartic acid repeat polymorphism in the asporin gene with knee-osteoarthritis susceptibility in Han Chinese. J Hum Genet. 2006; 51(12):1068-72. 

IF=2.275

 

57.   Miyamoto Y, Shi D, Nakajima M, Ozaki K, Sudo A, Kotani A, Uchida A, Tanaka T, Fukui N, Tsunoda T, Takahashi A, Nakamura Y, Jiang Q, Ikegawa S. Common variants in DVWA on chromosome 3p24.3 are associated with susceptibility to knee osteoarthritis. Nat Genet. 2008; 40(8):994-8. 

IF=25.556

 

58.   Miyamoto Y, Mabuchi A, Shi D, Kubo T, Takatori Y, Saito S, Fujioka M, Sudo A, Uchida A, Yamamoto S, Ozaki K, Takigawa M, Tanaka T, Nakamura Y, Jiang Q, Ikegawa S. A functional polymorphism in the 5' UTR of GDF5 is associated with susceptibility to osteoarthritis. Nat Genet. 2007; 39(4):529-33. 

IF=25.556

 

59.    Chapman K, Takahashi A, Meulenbelt I, Watson C, Rodriguez-Lopez J, Egli R, Tsezou A, Malizos KN, Kloppenburg M, Shi D, Southam L, van der Breggen R, Donn R, Qin J, Doherty M, Slagboom PE, Wallis G, Kamatani N, Jiang Q, Gonzalez A, Loughlin J, Ikegawa S. A meta-analysis of European and Asian cohorts reveals a global role of a functional SNP in the 5' UTR of GDF5 with osteoarthritis susceptibility. Hum Mol Genet. 2008; 17(10):1497-504..

IF=7.806

 

60.   Nakamura T, Shi D, Tzetis M, Rodriguez-Lopez J, Miyamoto Y, Tsezou A, Gonzalez A, Jiang Q, Kamatani N, Loughlin J, Ikegawa S. Meta-analysis of association between the ASPN D-repeat and osteoarthritis. Hum Mol Genet. 2007; 16(14):1676-81. 

IF=7.806

 

专利

2179337   ZL 2011 2 0260602.2      踝关节屈伸运动器        2011.07.22        2012.04.25        蒋青,陈东阳,叶迎海,徐志宏,史冬泉,秦江辉,戴进

1311213                ZL 2011 1 0206087.4      踝关节屈伸运动器        2011.07.22        2013.11.27     蒋青,陈东阳,叶迎海,徐志宏,史冬泉,秦江辉,戴进

2476940   ZL 2012 2 0105740.8      股骨髓腔中心线定位器 2012.03.20        2012.10.24        蒋青,陈东阳,徐志宏,史冬泉,戴进,秦江辉

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