学术成果:
近 3 年,转让技术 1 项,主持省部级等项目 4 项、横向项目 8 项,总经费 500 余万;2023年获批衢州市首批省级专家服务示范团(仅 2 个项目入选),2024 年获批人社部专家服务基层示范团(浙江省唯一一项)。以通讯作者和第一作者身份在Chemical Engineering Journal、Green Chemistry、The Journal of Organic Chemistry等国际专业学术期刊上发表SCI论文 14 篇(IF>100);申报发明专利 22 项(已授权 17 项,实审 4 项);参与编写学术专著 4 部;担任西南林业大学和沈阳化工大学硕士生导师、多家企业技术顾问;获得优秀指导教师奖、延长石油优秀博士奖学金和中国科学院三好学生;担任Chemical Engineering Journal、Green Chemistry、ACS Applied Materials & Interfaces等数十个国际著名SCI期刊的特邀审稿人。
****技术(保密要求)被企业应用于实际生产,每年可为企业节约千万元费用。Mn(OTf)2/TBHP催化2, 3-环戊烯吡啶选择性氧化体系被多个医药企业采用,极大地降低了6, 7-二氢-5H-环戊基并[b]吡啶-5-酮的生产成本。衣康酸酯化技术转让给浙江国光生化股份有限公司,丰富了浙江国光生化股份有限公司的产品种类,对提升企业竞争力发挥了重大作用。
技术转让:
(1)衣康酸酯化技术,2023年,小试工艺。
主持项目:
(1)横向课题,液晶中间体合成研究
(2)纵向课题,单原子催化空气氧化环己烷制备己二酸
(3)纵向课题,精馏残渣资源化利用
(4)纵向课题,含氟苯酚液晶中间体合成研究
(5)横向课题,HMF选择性氧化研究
(6)横向课题,微藻高效培养体系研发
(7)横向课题,脂肪族二酸制备技术研究
(8)横向课题,医药化工领域产品纯化与分离应用
(9)横向课题,有机化工残渣资源化利用研究
(10)横向课题,医药中间体合成工艺研究
代表论文
(1) L. Y. Jiang, J. Shang, X. Y. Peng, Z. L. Li, M. Q. Zhu, Y. W. Cheng,* P. F. Xie,* L. H. Ren*, Single Atom Catalysts Enable Quasi-Homogeneous Synthesis of Quinazoline, Chemical Engineering Journal, 2023, 474: 145651
(2) Z. Y. Ju, L. N. Song, M. B. Chong, D. G. Cheng, Y. Hou, X. M. Zhang, Q. H. Zhang* and L. H. Ren*, Selective Aerobic Oxidation of Csp3-H Bonds Catalyzed by Yeast-Derived Nitrogen, Phosphorus and Oxygen Co-doped Carbon Materials, J. Org. Chem., 2022, 87 (6): 3978-3988.
(3) Z. Y. Yan, X. Y. Shen, B. L. Zhou, R. Y. Pan, Bo Zhang, C. Z. Zhao, L. H. Ren*, J. J. Ming*, Precise analysis of T4 polynucleotide kinase and inhibition by coupling personal glucose meter with split DNAzyme and ligation-triggered DNA walker, Sensor Actuat. B-Chem., 2021, 326, 128831.
(4) L. Y. Jiang, J. J. Ming, L. Y. Wang, Y. Y. Jiang, L. H. Ren*, Z. C. Wang, W. C. Cheng, Visible-light-induced selective aerobic oxidation of sp3 C-H bonds catalyzed by a heterogeneous AgI/BiVO4 catalyst, Green Chem., 2020, 22 (5)1156-1163.
(5) L. H. Ren, L. Y. Wang, Y. Lv, G. S. Li, S. Gao*, Direct oxidation of the Csp3-H bonds of N-heterocyclic compounds to give the corresponding ketones using a reusable heterogeneous MnOx-N@C catalyst, Chin. J. Catal., 2016, 37(8): 1216-1221.
(6) L. H. Ren, L. Y. Wang, Y. Lv, S. S. Shang, B. Chen, S. Gao*, Synthesis of 6,7-dihydro-5H-cyclopenta[b]pyridin-5-one analogues through manganese-catalyzed oxidation of the CH2 adjacent to pyridine moiety in water, Green Chem., 2015, 17(4): 2369-2372.
(7) L. H. Ren, L. Y. Wang, Y. Lv, G. S. Li, S. Gao*, Synergistic H4NI-AcOH catalyzed oxidation of the Csp3-H bonds of benzylpyridines with molecular oxygen, Org. Lett., 2015, 17(9): 2078-2081.
(8) L. H. Ren, L. Y. Wang, Y. Lv, G. S. Li, S. Gao*, An effective method for the construction of esters using Cs2CO3 as oxygen source, Org. Lett., 2015, 17(21): 5172-5175.