Publication List (^# Equal contribution; * Corresponding author)

2024

12.   Designing nanotheranostics with machine learning

Lang Rao*, Yuan Yuan, Xi Shen, Guocan Yu & Xiaoyuan Chen*. Nature Nanotechnology, 2024, 19, in press. 

11.   Targeting Immunoproteasome in Polarized Macrophages Ameliorates Experimental Emphysema via Activating NRF1/2-P62 Axis and Suppressing IRF4 Transcription

Bingxin Guo^#, Xing Shi^#, Qiong Jiang^#, Yuanwei Pan, Yuqiong Yang, Yuanyuan Liu, Shuyu Chen, Wenjiao Zhu, Laibin Ren, Ruifang Liang, Xue Chen, Haizhao Xu, Laiyou Wei, Yongjian Lin, Jinyong Wang, Chen Qiu, Haibo Zhou, Lang Rao*, Lingwei Wang*, Rongchang Chen*, & Shanze Chen*. Advanced Science, 2024, 11, 2405318. 

10.   Engineered Cellular Vesicles Displaying Glycosylated Nanobodies for Cancer Immunotherapy 

Jicheng Wu^#, Hailin Lu^#, Ximing Xu, Lang Rao*, & Yun Ge*. Angewandte Chemie International Edition, 2024, 63, e202404889. 

9.   Genetically Edited Cascade Nanozymes for Cancer Immunotherapy 

Jing Zhang^#, Yuanwei Pan^#, Lujie Liu, Yangtao Xu, Chenchen Zhao, Wei Liu*, & Lang Rao*. ACS Nano, 2024, 18, 12295-12310. 

8.   Neutrophil Membrane-Camouflaged Polyprodrug Nanomedicine for Inflammation Suppression in Ischemic Stroke Therapy 

Ya Zhao^#, Qian Li^#,*, Jingyan Niu, Erliang Guo, Chenchen Zhao, Jian Zhang, Xue Liu, Lihua Wang, Lang Rao*, Xiaoyuan Chen*, & Kuikun Yang*. Advanced Materials, 2024, 36, 2311803. 

7.   3D-Printed Dendritic Cell Vaccines for Post-Surgery Cancer Immunotherapy

Yangtao Xu^#, Wenxiang Zhu^#, Jicheng Wu, Lujie Liu, Ludan Yue, Xueyang Zhang, Jiayi Li, Peng She, Jingjing Yang, Chengliang Sun, Ximing Xu*, & Lang Rao*. Advanced Functional Materials, 2024, 34, 2400507. 

6.   A Guanidinobenzol-Rich Polymer Overcoming Cascade Delivery Barriers for CRISPR-Cas9 Genome Editing 

Shuang Liang#, Ning Ma^#, Xingang Li^#, Kaiqing Yun, Qian-Fang Meng, Kongshuo Ma, Ludan Yue, Lang Rao*, Xiaoyuan Chen*, & Zhaohui Wang*. Nano Letters, 2024, 45, 6872-6880. (Featured as Cover).

5.   Engineered Bio-Based Hydrogels for Cancer Immunotherapy 

Yuxuan Peng, Shuang Liang, Qian-Fang Meng, Dan Liu, Kongshuo Ma, Mengli Zhou, Kaiqing Yun, Lang Rao*, & Zhaohui Wang*. Advanced Materials, 2024, 36, 2313188. 

4.   Triple Hybrid Cellular Nanovesicles Promote Cardiac Repair after Ischemic Reperfusion 

Jialin Lai^#, Qi Pan^#, Guihao Chen^#, Yu Liu, Cheng Chen, Yuanwei Pan, Lujie Liu, Binglin Zeng, Ling Yu, Yunsheng Xu, Jinyao Tang, Yuejin Yang*, & Lang Rao*. ACS Nano, 2024, 18, 4443-4455. (Featured as Cover).

3.   Ferroptosis Amplifier Remodels Redox Homeostasis for Enhanced Cancer Chemoimmunotherapy 

Jing Zhang^#, Yuanwei Pan#, Lujie Liu, Jicheng Wu, Chenchen Zhao, Lang Rao*, & Wei Liu*. ACS Materials Letters, 2024, 6, 2153-2164. 

2.   Genetically engineered nanomodulators elicit potent immunity against cancer stem cells by checkpoint blockade and hypoxia relief 

Yuanwei Pan^#, Ling Yu^#, Lujie Liu, Jing Zhang, Shuang Liang, Badri Parshad, Jialin Lai, Li-Min Ma*, Zhaohui Wang*, & Lang Rao*. Bioactive Materials, 2024, 38, 31-44.  

1.   Tumor Microenvironment-Responsive Nanoparticles Amplifying STING Signaling Pathway for Cancer Immunotherapy 

Dan Liu, Shuang Liang, Kongshuo Ma, Qian-Fang Meng, Xingang Li, Jian Wei, Mengli Zhou, Kaiqing Yun, Yuanwei Pan, Lang Rao*, Xiaoyuan Chen*, & Zhaohui Wang*. Advanced Materials, 2024, 36, 2304845. 

2023

8.   Inhalation delivery of dexamethasone with iSEND nanoparticles attenuates the COVID-19 cytokine storm in mice and non-human primates 

Qian-Fang Meng^#, Wanbo Tai^#, Mingyao Tian^#, Xinyu Zhuang^#, Yuanwei Pan, Jialin Lai, Yangtao Xu, Zhiqiang Xu, Min Li, Guangyu Zhao, Guang-Tao Yu, Guocan Yu, Rongchang Chen, Ningyi Jin, Xiao Li*, Gong Cheng*, Xiaoyuan Chen*, & Lang Rao*. Science Advances, 2023, 9, eadg3277. 

7.   Macrophages in immunoregulation and therapeutics 

Shanze Chen^#, Abdullah F. Saeed^#, Quan Liu^#, Qiong Jiang, Haizhao Xu, Gary Guishan Xiao*, Lang Rao*, & Yanhong Duo*. Signal Transduction and Targeted Therapy, 2023, 8, 207. (Highly Cited Paper).

6.   Vesicular Antibodies: Shedding Light on Antibody Therapeutics with Cell Membrane Nanotechnology 

Chenchen Zhao, Yuanwei Pan, Guocan Yu*, Xing-Zhong Zhao, Xiaoyuan Chen*, & Lang Rao*. Advanced Materials, 2023, 35, 2207875. 

5.   Chromium Nanoparticles Improve Macrophage and T Cell Infiltration for Cancer Immunotherapy 

Quan Liu^#, Zhe Sun^#, Yanhong Duo^#, Lei Yin, Kong-Peng Lv, Ludan Yue, Qian-Fang Meng, Dingmeng Nie, Jiaojuan Chen, Dixian Luo*, Li-Ping Liu*, & Lang Rao*. ACS Materials Letters, 2023, 5, 1738-1751. (Featured as Supplementary Cover).

4.   Harnessing Nanomaterials for Cancer Sonodynamic Immunotherapy 

Shuang Liang, Jianjun Yao, Dan Liu, Lang Rao*, Xiaoyuan Chen*, & Zhaohui Wang*. Advanced Materials, 2023, 35, 2211130. 

3.   Boosting Checkpoint Immunotherapy with Biomaterials 

Lujie Liu^#, Yuanwei Pan^#, Chenchen Zhao, Peng Huang*, Xiaoyuan Chen*, & Lang Rao*. ACS Nano, 2023, 17, 3225-3258. 

2.   In situ formed scaffold with royal jelly-derived extracellular vesicles for wound healing 

Dehong Tan, Wenxiang Zhu, Lujie Liu, Yuanwei Pan, Yangtao Xu, Qinqin Huang, Lingling Li, & Lang Rao*. Theranostics, 2023, 13, 2811-2824. (Featured as Back Cover).

1.   Inhaled drug delivery: Past, present, and future 

Ludan Yue, Xueyang Zhang, Chenchen Zhao, Rongchang Chen, Xiaoyuan Chen*, & Lang Rao*. Nano Today, 2023, 52, 101942.

2022

6.   Metal-free bioorthogonal click chemistry in cancer theranostics  

Dan Wu^#,*, Kuikun Yang^#, Zhankui Zhang, Yunxuan Feng, Lang Rao*, Xiaoyuan Chen*, & Guocan Yu*. Chemical Society Reviews, 2022, 51, 1336-1376. (Featured as Inside Cover). 

5.   Nanomaterial-mediated ablation therapy for cancer stem cells  

Yuanwei Pan, Lujie Liu, Lang Rao*, & Xiaoyuan Chen*. Matter, 2022, 5, 1367-1390.

4.   Supramolecular engineering of cell membrane vesicles for cancer immunotherapy  

Shaolong Qi, Haiyan Zhang, Xueyan Zhang, Xinyang Yu, Yajun Wang, Qian-Fang Meng, Kai Yang, Bing Bai, Rui Tian, Shoujun Zhu*, Lang Rao*, Feihe Huang, & Guocan Yu*. Science Bulletin, 2022, 67, 1898-1909.

3.   A decoy microrobot that removes SARS-CoV‑2 and its variants in wastewater   

Jialin Lai^#, Qian-Fang Meng^#, Mingyao Tian^#, Xinyu Zhuang, Pan Pan, Liang Du, Lin Deng, Jinyao Tang, Ningyi Jin, & Lang Rao*. Cell Reports Physical Science, 2022, 3, 101061.

2.   Neutrophil membrane-coated immunomagnetic nanoparticles for efficient isolation and analysis of circulating tumor cells  

Xianjia Wu^#, Zhousheng Lin^#, Chenchen Zhao, Lujie Liu, Kelin Zhang, Jialin Lai, Qian-Fang Meng, Gaungyu Yao, Qinqin Huang*, Xing-Zhong Zhao*, & Lang Rao*. Biosensors & Bioelectronics, 2022, 213, 114425.

1.   Engineered extracellular vesicles and their mimics in cardiovascular diseases  

Jialin Lai, Chaobo Huang, Yuxuan Guo, & Lang Rao*. Journal of Controlled Release, 2022, 347, 27-43.

2021

5.   Genetically Programmable Fusion Cellular Vesicles for Cancer Immunotherapy 

Qian-Fang Meng^#, Yuyue Zhao^#, Chunbo Dong^#, Lujie Liu, Yuanwei Pan, Jialin Lai, Zhida Liu, Guang-Tao Yu*, Xiaoyuan Chen*, & Lang Rao*. Angewandte Chemie International Edition, 2021, 60, 26320-26326.

4.   Capturing Cytokines with Advanced Materials: A Potential Strategy to Tackle COVID-19 Cytokine Storm 

Qian-Fang Meng#, Rui Tian#, Haiyi Long, Xianjia Wu, Jialin Lai, Olga Zharkova, Jiong-Wei Wang*, Xiaoyuan Chen*, & Lang Rao*. Advanced Materials, 2021, 33, 2100012. (Highlighted by MaterialsViews).

3.   Engineered Cell Membrane-Derived Nanoparticles in Immune Modulation 

Yixiao Yang, Kai Wang, Yuanwei Pan, Lang Rao*, & Gaoxing Luo*. Advanced Science, 2021, 8, 2102330.

2.   A platelet-mimicking theranostic platform for cancer interstitial brachytherapy 

Meng Lyu, Mingzhu Chen, Lujie Liu, Daoming Zhu, Xianjia Wu, Yang Li*, Lang Rao*, & Zhirong Bao*. Theranostics, 2021, 11, 7589-7599.

1.   Supramolecular cancer nanotheranostics

Jiong Zhou#, Lang Rao#, Guocan Yu*, Timothy R. Cook*, Xiaoyuan Chen*, & Feihe Huang*. Chemical Society Reviews, 2021, 50, 2839-2891. 

Before Joining to SZBL

10.   Decoy nanoparticles protect against COVID-19 by concurrently adsorbing viruses and inflammatory cytokines 

Lang Rao^#, Shuai Xia^#, Wei Xu^#, Rui Tian, Guocan Yu, Chenjian Gu, Pan Pan, Qian-Fang Meng, Xia Cai, Di Qu, Lu Lu*, Youhua Xie*, Shibo Jiang*, & Xiaoyuan Chen*. Proceedings of the National Academy of Sciences (PNAS), 2020, 117, 27141-27147. (Featured as Cover; Highlighted by The Scientist; ChemistryViews; Inverse; Infosurhoy; Scitech Daily). 

9.   Hybrid cellular membrane nanovesicles amplify macrophage immune responses against cancer recurrence and metastasis 

Lang Rao^#, Lei Wu^#, Zhida Liu^#, Rui Tian, Guocan Yu, Zijian Zhou, Kuikun Yang, Hong-Gang Xiong, Anli Zhang, Guang-Tao Yu, Wenjing Sun, Han Xu, Jingya Guo, Andrew Li, Hongmin Chen*, Zhi-Jun Sun*, Yang-Xin Fu*, & Xiaoyuan Chen*. Nature Communications, 2020, 11, 4909. (Highly Cited Paper).

8.   Activating Macrophage-Mediated Cancer Immunotherapy by Genetically Edited Nanoparticles 

Lang Rao, Shu-Kun Zhao, Churan Wen, Rui Tian, Lisen Lin, Bo Cai, Yue Sun, Fei Kang, Zhen Yang, Liangcan He, Jing Mu, Qian-Fang Meng, Guangyu Yao*, Ni Xie*, & Xiaoyuan Chen*. Advanced Materials, 2020, 32, 2004853. (Highlighted by MaterialsViews).

7.   Engineering Macrophages for Cancer Immunotherapy and Drug Delivery 

Yuqiong Xia^#, Lang Rao^#, Huimin Yao, Zhongliang Wang*, Pengbo Ning*, & Xiaoyuan Chen*. Advanced Materials, 2020, 32, 2002054. (Highly Cited Paper).

6.   A Biomimetic Nanodecoy Traps Zika Virus to Prevent Viral Infection and Fetal Microcephaly Development

Lang Rao^#, Wenbiao Wang^#, Qian-Fang Meng, Mingfu Tian, Bo Cai, Yingchong Wang, Aixin Li, Ming-Hui Zan, Feng Xiao, Lin-Lin Bu, Geng Li, Andrew Li, Yingle Liu, Shi-Shang Guo, Xing-Zhong Zhao, Tza-Huei Wang, Wei Liu*, & Jianguo Wu*. Nano Letters, 2019, 19, 2215-2222. (Featured as Inside Cover).

5.   Cancer Cell Membrane-Coated Nanoparticles for Personalized Therapy in Patient-Derived Xenograft Models 

Lang Rao, Guang-Tao Yu, Qian-Fang Meng, Lin-Lin Bu, Rui Tian, Li-Sen Lin, Hongzhang Deng, Weijing Yang, Ming-Hui Zan, Jianxun Ding, Andrew Li, Haihua Xiao*, Zhi-Jun Sun*, Wei Liu*, & Xiaoyuan Chen*. Advanced Functional Materials, 2019, 29, 1905671.

4.   Platelet-Facilitated Photothermal Therapy of Head and Neck Squamous Cell Carcinoma 

Lang Rao^#, Lin-Lin Bu^#, Liang Ma, Wenbiao Wang, Huiqin Liu, Da Wan, Andrew Li, Shi-Shang Guo, Wen-Feng Zhang, Xing-Zhong Zhao, Zhi-Jun Sun*, & Wei Liu*. Angewandte Chemie International Edition, 2018, 57, 986-991.

3.   Platelet–Leukocyte Hybrid Membrane-Coated Immunomagnetic Beads for Highly Efficient and Highly Specific Isolation of Circulating Tumor Cells 

Lang Rao^#, Qian-Fang Meng^#, Qinqin Huang, Zixiang Wang, Guang-Tao Yu, Andrew Li, Weijie Ma, Nangang Zhang, Shi-Shang Guo, Xing-Zhong Zhao, Kan Liu*, Yufeng Yuan*, & Wei Liu*. Advanced Functional Materials, 2018, 28, 1803531. (Featured as Back Cover).

2.   Microfluidic Electroporation-Facilitated Synthesis of Erythrocyte Membrane-Coated Magnetic Nanoparticles for Enhanced Imaging-Guided Cancer Therapy 

Lang Rao, Bo Cai, Lin-Lin Bu, Qing-Quan Liao, Shi-Shang Guo, Xing-Zhong Zhao, Wen-Fei Dong*, & Wei Liu*. ACS Nano, 2017, 11, 3496-3505. (Highly Cited Paper).

1.   Cancer Cell Membrane-Coated Upconversion Nanoprobes for Highly Specific Tumor Imaging 

Lang Rao, Lin-Lin Bu, Bo Cai, Jun-Hua Xu, Andrew Li, Wen-Feng Zhang, Zhi-Jun Sun, Shi-Shang Guo, Wei Liu*, Tza-Huei Wang, & Xing-Zhong Zhao. Advanced Materials, 2016, 28, 3460-3466. (Highly Cited Paper).