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成果及论文

Post-2020

13. C.T. Tan, X. Xu, Y. Qiao*, Y. Wang*. A peptidoglycan storm caused by β-lactam antibiotic’s action on host microbiota drives Candida albicans infection. Nat Commun 12, 2560 (2021). https://www.nature.com/articles/s41467-021-22845-2

12. Y. Qiao*, H. Hayashi, SC. Teo. Chemical Toolbox to Decode the Microbiota Lexicon. Chemistry: an Asian Journal. 2020. DOI: org/10.1002/asia.202000541 (For the special collection of 50th anniversary of SNIC) https://onlinelibrary.wiley.com/doi/epdf/10.1002/asia.202000541

Pre-NTU

11. ZX. Huang, JH. Wang, XL. Xu, HS. Wang, Y. Qiao, WC. Chu, SL. Xu, L. Chai, F. Cottier, N. Pavelka, M. Oosting, LAB. Joosten, M. Netea, CYL. Ng, KP. Leong, P. Kundu, KP. Lam, S. Petterson, Y. Wang. Antibody neutralization of microbiota-derived circulating peptidoglycan dampens inflammation and ameliorates autoimmunity. Nat. Microbiol. 2019, 4, 766–773. https://www.nature.com/articles/s41564-019-0381-1

10. MM. Zhang, Y. Qiao‡, EL. Ang, H. Zhao. Using Natural Products for Drug Discovery: the Impact of the Genomic Era. Expert Opin Drug Discov. 2017, 12(5): 475-487. https://www.tandfonline.com/doi/abs/10.1080/17460441.2017.1303478?journalCode=iedc20

9. V. Srisuknimit, Y. Qiao‡, K. Schaefer, D. Kahne, S. Walker. Peptidoglycan Cross-Linking Preferences of Staphylococcus aureus Penicillin-Binding Proteins Have Implications for Treating MRSA Infections. J. Am. Chem. Soc. 2017, 139(29): 9791-9794. (equal contribution) https://pubs.acs.org/doi/10.1021/jacs.7b04881

8. Y. Qiao, V. Srisuknimit‡, F. Rubino, K. Schaefer, N. Ruiz, S. Walker, D. Kahne. Lipid II Overproduction Allows Direct Assay of Transpeptidase Inhibition by Beta-lactams. Nat. Chem. Biol. 2017, 13(7): 793-798. (‡ equal contribution) https://www.nature.com/articles/nchembio.2388

7. K. Schaefer, L. Matano, Y. Qiao, D. Kahne, S. Walker. In Vitro Reconstitution Demonstrates the Cell Wall Ligase Activity of LCP proteins. Nat. Chem. Biol. 2017, 13(4): 396-401. https://www.nature.com/articles/nchembio.2302

6. W. Lee, K. Schaefer, Y. Qiao, V. Srisuknimit, H. Steinmetz, R. Müller, D. Kahne, S. Walker. The Mechanism of Action of Lysobactin. J. Am. Chem. Soc. 2015, 138(1): 100-3. https://pubs.acs.org/doi/10.1021/jacs.5b11807

5. Y. Qiao, MD. Lebar, K. Schirner, K. Schaefer, H. Tsukamoto, D. Kahne, S. Walker. Detection of Lipid-linked Peptidoglycan Precursors by Exploiting an Unexpected Transpeptidase Reaction. J. Am. Chem. Soc. 2014, 136(42): 14678-81. https://pubs.acs.org/doi/abs/10.1021/ja508147s

4. Y. Rebets, T. Lupoli, Y. Qiao, K. Schirner, R. Villet, D. Hooper, D. Kahne, S. Walker. Moenomycin Resistance Mutations in Staphylococcus aureus Reduce Peptidoglycan Chain Length and Cause Aberrant Cell Division. ACS Chem Biol 2014, 9(2): 459-673. https://pubs.acs.org/doi/abs/10.1021/cb4006744

3. K. Fukushima, JPK. Tan, PA. Korevar, Y. Y. Yang, J. Pitera, A. Nelson, H. Maune, DJ. Coady, JE. Frommer, AC. Engler, Y. Huang, K. Xu, Z. Ji, Y. Qiao, W. Fan, L. Li, N. Wiradharma, EW. Meijer, JL. Hedrick. Broad Spectrum Antimicrobial Supramolecular Assemblies with Distinctive Size and Shape. ACS Nano 2012, 6, 9191-9199. https://pubs.acs.org/doi/abs/10.1021/nn3035217

2. Y. Qiao, C. Yang, DJ. Coady, ZY. Ong, JL. Hedrick, Y. Y. Yang. Highly Dynamic Biodegradable Micelles Capable of Lysing Gram-positive and Gram-negative Bacterial Membrane. Biomaterials 2012, 33, 1146-1153 https://www.sciencedirect.com/science/article/abs/pii/S0142961211012233

1. Y. Qiao, S. Kumar, W. P. Malachowski. Enatioselective Synthesis of Bicarbocyclic Structures with All Carbon Quaternary Stereocenters through Sequential Cross Metathesis and Intramolecular Rauhut-Currier Reaction. Tet. Lett. 2010, 51, 2636-2638 https://www.sciencedirect.com/science/article/abs/pii/S004040391000434X