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成果及论文

 

(49) Electrochemically time-dependent oxidative coupling/coupling-cyclization reaction between heterocycles: tunable synthesis of polycyclic indole derivatives with fluorescence properties. Zuozhou Ning, Zhicheng Zhang, Qingsong Yan, Naifu Zhou, Linzi Wen, Xichao Peng, Yu Tang, Pengju Feng*. Science China Chemistry. 2022, 65, 1962-1967.

 

(48) Electrochemically controlled dearomative 2,3-difunctionalization of indoles to synthesize oxoindoline derivatives. Xichao Peng, Linzi Wen, Zuozhou Ning, Zhicheng Zhang, Chengbo Sun, Yu Tang, Pengju Feng*. Organic Chemistry Frontiers. 2022, 9, 3800-3806.

 

(47) In vivo genome-wide CRISPR screening identifies ZNF24 as a negative NF-kappaB modulator in lung cancer. Lu Liu, Yuxi Lei, Wensheng Chen, Qian Zhou, Zongyao Zheng, Guandi Zeng, Wanting Liu, Pengju Feng, Zhiyi Zhang, Lei Yu, Liang Chen*, Cell & Bioscience, 2022, 12, 193; Doi.org/ 10.1186/s13578-022-00933-0.

 

(46) Tunable alkoxy-nucleophilic addition under photochemical condition: Dioxidation of gem-difluoroalkenes with O2. Yuanwei Liang, Naifu Zhou, Guojian Ma, Linzi Wen, Xing Wu*, Pengju Feng*, Molecular Catalysis, 2022, 528, 112373; Doi.org/ 10.1016/j.mcat.2022.112373.

 

(45) Elastic-Electric Coefficient-Sensitive Hydrogel Sensors toward Sweat Detection. Bin shen, Wenjing Peng, Bingtian Su, Lizhen Wu, Zhihao Liu, Huihua Xu, Jiexiu Zhao, Pengju Feng, Fengyu Li*, Analytical Chemistry, 2022, 94, 1910; Doi.org/ 10.1021/acs.analchem.1c05363.

 

(44) Thermally Stable, Solvent Resistant, and Multifunctional Thermosetting Polymer Networks with High Mechanical Properties Prepared from Renewable Plant Phenols via Thiol-Ene Photo Click Chemistry. Zirun Lin, Yanzi Ke, Xichao Peng, Xing Wu, Chaoqun Zhang, Hui Zhao*, Pengju Feng* ACS Applied Polymer Materials, 2022, 4, 5330; Doi.org/ 10.1021/acsapm.2c00333.

 

(43) F-18- or Lu-177-labeled bivalent ligand of fibroblast activation protein with high tumor uptake and retention. Hongsheng Li, Shimin Ye, Li Li, Jiawei Zhong, Qiongsong Yan, Yuhua Zhong, Pengju Feng, Kongzhen Hu* European Jouranl of Nuclear Medicine and Molecular Imaging, 2022, 49, 2705; Doi.org/ 10.1007/s00259-022-05757-1.

 

(42) Radiosynthesis and Preclinical Evaluation of Bispecific PSMA/FAP Heterodimers for Tumor Imaging. Kongzhen Hu, Yong Huang, Shimin Ye, Jiawei Zhong, Qiongsong Yan, Yuhua Zhong, Lilan Fu, Pengju Feng, Hongsheng Li* Pharmaceuticals, 2022, 15, 383; Doi.org/10.3390/ph15030383.

 

(41) Electro-oxidative C–H amination of heteroarenes with aniline derivatives via radical–radical cross coupling. Xichao Peng, Junhao Zhao, Guojian Ma, Yan Wu, Shiyu Hu, Zhixiong Ruan*, Pengju Feng*, Green Chemistry, 2021, 23, 8853; Doi.org/10.1039/D1GC02821A.

 

(40) Electro-Oxidative Coupling of Azoles with 2- and 3-Haloindoles/Thiophenes Providing Access to 2/3-Halo(Azol-1-Yl)Indoles/Thiophenes. Naifu Zhou, Jianchao Yu, Liyuan Hou, Xing Wu, Zhixiong Ruan*, Pengju Feng*. Advanced Synthesis & Catalysis. 2022, 364, 35-40; doi.org/10.1002/adsc.202100958

 

(39) A Diverse Micromorphology of Photonic Crystal Chips for Multianalyte Sensing. Yu Huang, Lingxiao Liu, Xian Yang, Xiaoyu Zhang, Bing Yan, Lei Wu, Pengju Feng, Xiaoding Lou, Fan Xia, Yanling Song, Fengyu Li, Small, 2021, doi.org/10.1002/smll.202006723.

 

(38) Electro-Oxidative C–N Bond Formation through Azolation of Indole Derivatives: An Access to 3-Substituent-2-(Azol-1-yl)indoles. Naifu Zhou, Junhao Zhao, Chengbo Sun, Yuqin Lai, Zhixiong Ruan*, Pengju Feng*, Journal of Organic Chemistry. 2021, 86, 16059-16067; doi.org/10.1021/acs.joc.1c01271.

 

(37) Direct Electrochemical Synthesis of Sulfur-Containing Triazolium Inner Salts. Yueheng Li, Zhixing Huang, Guangquan Mo, Wei Jiang, Chengwei Zheng, Pengju Feng*, Zhixiong Ruan*, Chinese Journa of Chemistry. 2021, 39, 942-946.

 

(36) Novel 18F-Labeled Isonicotinamide-Based Radioligands for Positron Emission Tomography Imaging of Glycogen Synthase Kinase-3β. Yuhua Zhong, Shaoxi Yang, Jianyu Cui, Jie Wang, Lin Li, Yilin Chen, Junjie Chen, Pengju Feng, Shun Huang, Hongsheng Li, Yanjian Han, Ganghua Tang, Kongzhen Hu*, Mol. Pharmacetics, 2021, 18, 1277-1284.

 

(35) Rapid self-healing, multiple recyclability and mechanically robust plant oil-based epoxy resins enabled by incorporating tri-dynamic covalent bonding. Chaoqun Zhang*, Xiao Wang, Dunsheng Liang, Henghui Deng, Zirun Lin, Pengju Feng*, Qinwen Wang*. Journal of Materials Chemistry A 2021, 9, 18431-18439.

 

(34) Late-stage azolation of benzylic C‒H bonds enabled by electrooxidation. Zhixiong Ruan*, Zhixing Huang, Zhongnan Xu, Shaogao Zeng, Pengju Feng*, Peng-Hua Sun*. Science China Chemistry 2021, 64, 800-807.

 

(33) Consequent Construction of C–C and C–N Bonds via Palladium-Catalyzed Dual C–H Activation: Synthesis of Benzo[c]cinnoline Derivatives. Hongsheng Li, Junhao Zhao, Songjian Yi, Kongzhen Hu, Pengju Feng*, Organometallics 2021, 40, 880-889.

 

(32) Continuous-Flow Electrochemistry Promoted Aza-Wacker Cyclizations. Xichao Peng, Pengju Feng* Chinese Journal of Organic Chemistry, 2021, 41, 2918-2919.

 

(31) An Easy Access to Pyrogallol Derivatives Using a Practical Auxiliary, Xing Wu, Songjian Yi, Yifeng Huang, Ling Lin, Yu Tang*, Pengju Feng*, ChemistrySelect 2021, 6, 538-541..

 

(30) Photoredox initiated azole-nucleophilic addition: oxo-azolation of gem-difluoroalkenes

Xing Wu, Guojian Ma, Xichao Peng, Zuozhou Ning, Zirun Lin, Xiaoguang Chen, Yu Tang*, Pengju Feng*. Organic Chemistry Frontiers. 2021, 8, 4817-4877.

 

(29) Photodriven Regeneration of G-Quadruplex Aptasensor for Sensitively Detecting Thrombin. Liangliang Zhang, Xiaoyu Zhang, Pengju Feng, Qi Han, Wei Liu, Ying Lu*, Chunxia Song, Fengyu Li* Analytical chemistry 2020, 92, 7419-7424..

 

(28) Renewable Castor Oil based Waterborne Polyurethane Networks: Simultaneously Showing High Strength, Self-healing, Processability and Tunable Multi-shape Memory. Chaoqun Zhang*, Haiyan Liang, Dunsheng Liang, Zirun Lin, Qian Chen, Pengju Feng*, Qinwen Wang, Angew. Chem. Int. Ed. 2021, 60, 4289-4299..

 

(27) The investigation and bioorthogonal anticancer activity enhancement of a triphenylphosphine-labile prodrug of seleno-combretastatin-4. Liyuan Hou, Wei Huang, Jiaqi Cheng, Xuanru Deng, Haoqiang Lai, Zhen Chen, Zepang Zhan, Pengju Feng*, Yiqun Li*, Fang Yang*, Tianfeng Chen. Chem. Commun. 2020, 56, 14495-14498..

 

(26) A cysteine derivative-enabled ultrafast thiol-ene reaction for scalable synthesis of a fully bio-based internal emulsifier for high-toughness waterborne polyurethanes. Xiao Wang, Haiyan Liang, Jizhou Jiang, Qingwen Wang, Ying Luo, Pengju Feng*, Chaoqun Zhang*. Green Chem. 2020, 22, 5722.

 

(25) Adjusting lipid-water distribution coefficient of Iridium (III) complexes for enhancing its cellular penetration and treatment efficacy to antagonize cisplatin resistance in cervical cancer Wei Huang, Zhen Chen, Liyuan Hou, Pengju Feng*, Yiqun Li*, Tianfeng Chen, Dalton Transactions  2020, 49, 11556-11564.

 

(24) Facile One-pot Protocol of Derivatization Nitropyridines: Access to 3-Acetamidopyridin-2-yl 4-methylbenzenesulfonate Derivatives Ling, Lin, Xiaoguang Chen, Junhao Zhao, Suitao Lin, Guojian Ma, Xiaojian Liao*, Pengju Feng*, Heterocycl. Commun  2019, 25, 138-145;

 

(23) Tailoring the Performance of Vegetable Oil-Based Waterborne Polyurethanes through Incorporation of Rigid Cyclic Rings into Soft Polymer Networks Haiyan, Liang, Yanchun Li, Siying Huang, Kaixi Huang, Xueyi Zeng, Qianwen Dong, Chengguo Liu, Pengju Feng*, Chaoqun zhang*, ACS Sustainable Chem. Eng  2020, 8, 914-925.

 

(22) Total Synthesis of Thermoactinoamide A and its Analogue Yueguang Sun, Hang-bin Li, Rong Zhou, Hailin Wang, Pengju Feng*, Shihai Xu*, Heterocycles  2019, 98, 789-497.

 

(21) Simple Aggregation-Induced Emission-Based Multifunctional Fluorescent Dots for Cancer Therapy in Vitro. Xueran Lin, Junhao Zhao, Wei Huang, Hongxing Liu, Pengju Feng*,Fang Yang*, Tianfeng Chen. Chemistry an asian journal  2019, 14, 4160-4163.

 

(20) Electro-oxidative and Regioselective C-H Azolation of Phenol and Aniline Drivatives. Pengju Feng#*, Guojian Ma#, Xiaoguang Chen, Xing Wu, Ling Lin, Peng Liu, Tianfeng Chen*. Angew. Chem. Int. Ed. 2019, 131, 8488-8492.

 

(19) One-pot Protocol to Synthesize 2-Aminophenols from Anilines via Palladium-catalyzed C-H Acetoxylation. Junhao Zhao, Yifeng Huang, Guojian Ma, Ling Lin, Pengju Feng*. Organometallics 2019, 38, 2084-2091.  

 

(18) 实用导向基辅助下的邻苯二酚衍生物便捷合成(Facile Synthesis of Pyrocatechol Derivatives Using a Practical Auxiliary 林玲#,林学然#,冯鹏举*;合成化学 HECHENG HUAXUE2019, 9..

 

(17) 高校化学实验队伍中存在的问题及建议。 林玲,冯鹏举;广州化学,2019 11

 

(16) Synthesis and Biological Evaluation of Reniochalistatins A–E and a Reniochalistatin E Analogue. Rong Zhou,Yueguang sun,Hangbin Li, Weili Long, Xiaojian Liao, Pengju Feng*, Shihai Xu*. ChemMedChem 2018, 13, 2202-2207.

 

(15) Copper‐Catalyzed Direct C−H Bond Arylation of Benzoxazoles with Anilines. Pengju Feng, Guojian Ma, Tianyu Zhang, Changwei Wang*  Asian Journal of Organic Chemistry. 2018, 7, 788-792.

 

(14) Isolation and Synthesis of Misszrtine A: A Novel Indole Alkaloid From Marine Sponge-Associated Aspergillus sp. SCSIO XWS03F03 Rong Zhou, Xiaojian Liao, Hangbin Li, Jing Li, Pengju, Feng*, Bingxin Zhao*, Shihai Xu*. Front. Chem. 2018, 6, 212.

 

(13) Cancer-targeted design of bioresponsive prodrug with enhanced cellular uptake to achieve precise cancer therapy Yuanwei Liang, Wei Huang, Delong Zeng, Xiaoting Huang, Leung Chan, Chaoming Mei, Pengju, Feng; Choon-Hong Tan; Tianfeng Chen*. Drug delivery. 2018, 25, 1350-1361.

 

(12) Selenadiazole Derivatives Inhibit Angiogenesis-Mediated Human Breast Tumor Growth by Suppressing the VEGFR2Mediated ERK and AKT Signaling Pathways Haoqiang Lao, Xiaoyan Fu, Chengcheng Sang, Liyuan Hou, Pengju, Feng, Xiaoling Li, Tianfeng Chen*. Chemistry an asian journal  2018, 13, 1447-1457.

 

(11) Optically Probing the Localized to Delocalized Transition in the Mo2-Mo2Mixed-valence Systems. Yi Yang Wu#, Miao Meng#, Gang Yi Wang, Pengju Feng and Chun Y. Liu*. Chem. Commun., 2017, 53,3030-3033.

 

(10) Enhancement of Antiangiogenic Efficacy of Iron(II) Complex by Selenium Substitution. Haoqiang Lai, Xiang Zhang, Pengju, FengLina Xie, Jinjin Chen, Tianfeng Chen*. Chemistry an asian journal  2017, 12, 982-987.

 

(9) Access to a New Class of Synthetic Building Blocks via Trifluoromethoxylation of Pyridines and Pyrimidines. Pengju, Feng;Hojczyk, K.; Chenbo, zhang; Ming-Yu, Ngai*. Chem. science 2016, 7, 424-429. (equal contribution) (IF = 9.21) (highlighted in OPR&D)

 

(8) Trifluoromethoxylation of Arenes: Synthesis of Ortho-Trifluoromethoxylated Aniline Derivatives via OCF3-Migration. Hojczyk, K.;‡ Pengju, Feng;‡ Chenbo, zhang; Ming-Yu, Ngai*. Angew. Chem. Int.. Ed. 2014, 53, 14559-14563. (equal contribution) (IF = 11.26) (reviewed in synlett)

 

(7) An Approach to the Hexacyclic Skeleton of Trigonoliimines. Pengju, Feng; Yukai, Fan; Fazhen, Xue.; Weigang, Liu.; Songlei, Li.; Yian, Shi*. Org. Lett. 2011, 13, 5827-5829. (IF = 6.36)

 

(6) Facile Synthesis of 4-Methyl-5-hexyl- -butyrolactone via Nef Reaction as a Key Step. Zhi Li; Changwei Wang; Pengju Feng*. (* corresponding author) Helv. Chim. Acta. 2015, 98, 795-799. (IF = 1.14)

 

(5) Protocol for the Synthesis of ortho-Trifluoromethoxylated Aniline Derivatives. Pengju, Feng; Ming-Yu, Ngai*. J. Vis. Exp. (accept) (IF = 1.33)

 

(4) A Concise Approach to the Dalescnol Skeleton. Yukai, Fan.; Pengju, Feng.; Mao, Liu.; Hongjie, Pan.; Yian, Shi*. Organic Letters 2011, 13, 4494-4497. (IF = 6.36)

 

(3) Stereoselective construction of the tetracyclic core of Cryptotrione. Song, Chen.; Chao, Rong.; Pengju, Feng.; Songlei, Li.; Yian, Shi*. Org. Biomol. Chem. 2012, 10, 5518-5520. (IF = 3.56)

 

(2) An Approach to the Skeleton of Aspidophylline A. Qi Li, Guang Li, Shaobo Ma, Pengju Feng, and Yian Shi*. Org. Lett. 2013, 15, 2601-2603. (IF = 6.36)

 

(1) A Concise Approach to the spiroaminal Fragment of Marineosins. Guang Li, Xun Zhang, Qi Li, Pengju Feng, and Yian Shi*. Org. Biomol. Chem. 2013, 11, 2936-2938. (IF = 3.56);