发表论文：(#第一作者；*通讯作者)

代表性论文：

Wei-Zhu Liu, Shou-He Huang, Yu Wang, Chun-Yan Wang, Han-Qing Pan, Ke Zhao, Ping Hu, Bing-Xing Pan*, Wen-Hua Zhang*. Medial prefrontal cortex input to basolateral amygdala controls acute stress-induced short-term anxiety-like behavior in mice. Neuropsychopharmacology, 2023, 48:734-744.

Dong Lin^#, Lu-Hui Li#, Wen-Bing Chen#, Jiang Chen, Dong-Yan Ren, Zhi-Heng Zheng, Chang-Qin Zhao, Yan-Zi Zhong, Bin Luo, Hong-Yang Jing, Peng Chen, Su-Qi Zou, Xin-Sheng Lai, Tian Zhou, Ning Ding, Lei Li, Bing-Xing Pan*, Er-Kang Fei*. LHPP, a risk factor for major depressive disorder, regulates stress-induced depression-like behaviors through its histidine phosphatase activity. Molecular Psychiatry, 2023, 28:908–918. (Image, LHPP expression in neurons, Molecular Psychiatry, 2023, 28:517）

Han-Qing Pan, Xiao-Xuan Liu, Ye He, Jin Zhou, Cai-Zhi Liao, Wen-Jie You, Si-Ying Jiang, Xia Qin, Wen-Bing Chen, Er-Kang Fei, Wen-Hua Zhang, Bing-Xing Pan. Prefrontal GABAA(δ)R promotes fear extinction through enabling the plastic regulation of neuronal intrinsic excitability. Journal of Neuroscience, 2022, 42(29):5755-5770. (Featured Article)

Peng Chen#, Zi-Yang Liu#, Qian Zhang, Dong Lin, Song Lu, Jiang-Hong Liu, Hui-Feng Jiao, Xin-Sheng Lai, Su-Qi Zou, Shun-Qi Wang, Tian Zhou, Bao-Ming Li, Li Zhu*, Bing-Xing Pan*, Er-Kang Fei*. DSCAM deficiency leads to premature spine maturation and autism-like behaviors. Journal of Neuroscience, 2022, 42(4):532-551.

Xia Qin, Han-Qing Pan, Shou-He Huang, Jia-Xin Zou, Zhi-Heng Zheng, Xiao-Xuan Liu, Wen-Jie You, Zhi-Peng Liu, Jun-Li Cao, Wen-Hua Zhang*, Bing-Xing Pan*. GABAA(δ) receptor hypofunction in the amygdala-hippocampal circuit underlies stress-induced anxiety. Science Bulletin, 2022, 67:97-110.

Wen-Hua Zhang, Jun-Yu Zhang, Andrew Holmes, Bing-Xing Pan. Amygdala circuit substrates for stress adaptation and adversity. Biological Psychiatry, 2021, 89:847-856. (Cover) (Invited Review)

Wei-Zhu Liu#, Wen-Hua Zhang#, Zhi-Heng Zheng, Jia-Xin Zou, Xiao-Xuan Liu, Shou-He Huang, Wen-Jie You, Ye He, Jun-Yu Zhang, Xiao-Dong Wang, Bing-Xing Pan. Identification of a prefrontal cortex-to-amygdala pathway for chronic stress-induced anxiety. Nature Communications, 2020, 11:2221.

Wen-Hua Zhang, Wei-Zhu Liu, Ye He, Wen-Jie You, Jun-Yu Zhang, Hong Xu, Xiao-Li Tian, Bao-Ming Li, Lin Mei, Andrew Holmes, Bing-Xing Pan. Chronic stress causes projection-specific adaptation of amygdala neurons via small-conductance calcium-activated potassium channel downregulation. Biological Psychiatry, 2019, 85:812-828. (Commentary by C. Morel, S. Montgomery, M.H Han, Small-Conductance, Calcium-Activated Potassium Channels: A Key Circuit Determinant for Stress-Induced Amygdala Dysfunction. Biological Psychiatry, 2019, 85:784-786)

Jun-Yu Zhang#, Tao-Hui Liu#, Ye He, Han-Qing Pan, Wen-Hua Zhang, Xiao-Li Tian, Xiao-Ping Yin, Bao-Ming Li, Xiao-Dong Wang, Andrew Holmes, Ti-Fei Yuan, Bing-Xing Pan. Chronic stress remodels synapses in an amygdala circuit-specific manner. Biological Psychiatry, 2019, 85:189-201. (Commentary by G. Treccani, From Structure to Behavior: Circuit Specificity of Stress-Induced Synaptic Plasticity in the Basolateral Amygdala Projection Neurons. Biological Psychiatry, 2019, 85:e7-e9.)

Zhi-Peng Liu#, Qing-Hai He#, Han-Qing Pan, Jin Zhou, Ye He, Xiao-Bin Xu, Xiao-Ping Yin, Bao-Ming Li, Tian-Ming Gao*, Bing-Xing Pan*. Delta subunit containing GABAA receptors disinhibit lateral amygdala and facilitate fear learning in mice. Biological Psychiatry. 2017, 81(12): 990-1002.

2024

1. ‍‍Ren-Wen Han*, Zi-Yi Zhang, Chen Jiao, Ze-Yu Hu, Bing-Xing Pan*.Synergism between two BLA-to-BNST pathways for appropriate expression of anxiety-like behaviors in male mice.Nature Communications,2024,15:3455.

2023

1. Wei-Zhu Liu, Shou-He Huang, Yu Wang, Chun-Yan Wang, Han-Qing Pan, Ke Zhao, Ping Hu, Bing-Xing Pan*, Wen-Hua Zhang*. Medial prefrontal cortex input to basolateral amygdala controls acute stress-induced short-term anxiety-like behavior in mice. Neuropsychopharmacology, 2023, 48:734-744.

2. Dong Lin#, Lu-Hui Li#, Wen-Bing Chen#, Jiang Chen, Dong-Yan Ren, Zhi-Heng Zheng, Chang-Qin Zhao, Yan-Zi Zhong, Bin Luo, Hong-Yang Jing, Peng Chen, Su-Qi Zou, Xin-Sheng Lai, Tian Zhou, Ning Ding, Lei Li, Bing-Xing Pan*, Er-Kang Fei*. LHPP, a risk factor for major depressive disorder, regulates stress-induced depression-like behaviors through its histidine phosphatase activity. Molecular Psychiatry, 2023, 28:908–918. (Image, LHPP expression in neurons, Molecular Psychiatry, 2023, 28:517）

3. Wei-Zhu Liu#, Chun-Yan Wang#, Yu Wang, Mei-Ting Cai, Wei-Xiang Zhong, Tian Liu, Zhi-Hao Wang, Han-Qing Pan, Wen-Hua Zhang*, Bing-Xing Pan*. Circuit- and laminar-specific regulation of medial prefrontal neurons by chronic stress. Cell and Bioscience, 2023, 13:90.

2022

1. Xia Qin, Han-Qing Pan, Shou-He Huang, Jia-Xin Zou, Zhi-Heng Zheng, Xiao-Xuan Liu, Wen-Jie You, Zhi-Peng Liu, Jun-Li Cao, Wen-Hua Zhang*, Bing-Xing Pan*. GABAA(δ) receptor hypofunction in the amygdala-hippocampal circuit underlies stress-induced anxiety. Science Bulletin, 2022, 67:97-110.

2. Shou-He Huang#, Wei-Zhu Liu#, Xia Qin, Chen-Yi Guo, Qing-Cheng Xiong, Yu Wang, Ping Hu, Bing-Xing Pan*, Wen-Hua Zhang*. Association of Increased Amygdala Activity with Stress-Induced Anxiety but not Social Avoidance Behavior in Mice. Neuroscience Bulletin, 2022, 38:16-28.

3. Peng Chen#, Zi-Yang Liu#, Qian Zhang, Dong Lin, Song Lu, Jiang-Hong Liu, Hui-Feng Jiao, Xin-Sheng Lai, Su-Qi Zou, Shun-Qi Wang, Tian Zhou, Bao-Ming Li, Li Zhu*, Bing-Xing Pan*, Er-Kang Fei*. DSCAM deficiency leads to premature spine maturation and autism-like behaviors. Journal of Neuroscience, 2022, 42(4):532-551.

4. Yu Liu#, Ping Hu#, Zhi-Heng Zheng, Da Zhong, Wei-Chang Xie, Zhi-Bo Tang, Bing-Xing Pan*, Jun Luo*, Wen-Hua Zhang*, Xiao-Lei Wang*. Photoresponsive Vaccine-Like CAR-M System with High-Efficiency Central Immune Regulation for Inflammation-related Depression. Advanced Materials, 2022, 34(11):e2108525.

5. Han-Qing Pan, Xiao-Xuan Liu, Ye He, Jin Zhou, Cai-Zhi Liao, Wen-Jie You, Si-Ying Jiang, Xia Qin, Wen-Bing Chen, Er-Kang Fei, Wen-Hua Zhang, Bing-Xing Pan. Prefrontal GABAA(δ)R promotes fear extinction through enabling the plastic regulation of neuronal intrinsic excitability. Journal of Neuroscience, 2022, 42(29):5755-5770. (Featured Article)

6. Su-Qi Zou*,  Bing-Xing Pan. Post-synaptic specialization of the neuromuscular junction: junctional folds formation, function, and disorders. Cell and Bioscience, 2022, 12:93.

2021

1. Zhi-Heng Zheng#, Jiang-Long Tu#, Xiao-Hao Li, Qing Hua, Wei-Zhu Liu, Yu Liu, Bing-Xing Pan, Ping Hu, Wen-Hua Zhang. Neuroinflammation induces anxiety- and depressive-like behavior by modulating neuronal plasticity in the basolateral amygdala. Brain, Behavior, and Immunity, 2021, 91:505-518.

2. Wen-Hua Zhang, Jun-Yu Zhang, Andrew Holmes, Bing-Xing Pan. Amygdala circuit substrates for stress adaptation and adversity. Biological Psychiatry, 2021, 89:847-856. (Cover) (Invited Review)

3. Peng Chen#, Hong-Yang Jing#, Ming-Tao Xiong, Qian Zhang, Dong Lin, Dong-Yan Ren, Shun-Qi Wang, Dong-Min Yin, Yong-Jun Chen, Tian Zhou, Bao-Ming Li, Er-Kang Fei*, Bing-Xing Pan*. Spine impairment in mice high-expressing neuregulin 1 due to LIMK1 activation. Cell Death and Disease, 2021, 12:403.

4. Ji-Yun Peng*, Bing-Xing Pan. Microglial Calcium: An Exquisite Sensor for Neuronal Activity. Neuroscience Bulletin, 2021, 37:582-584.

5. Shi-Yu Peng#, Zhe Shi#, Dong-Sheng Zhou#, Xin-Yue Wang, Xing-Xing Li, Xiao-Li Liu, Wei-Di Wang, Guan-Ning Lin, Bing-Xing Pan, Valerie Voon, Anthony A. Grace, Markus Heilig, Ma-Li Wong, Ti-Fei Yuan. Reduced motor cortex GABABR function following chronic alcohol exposure. Molecular Psychiatry, 2021, 26:383-395.

6. Tian-Kun Hui, Xin-Sheng Lai, Xia Dong, Hong-Yang Jing, Zi-Yang Liu, Er-Kang Fei, Wen-Bing Chen, Shun-Qi Wang, Dong-Yan Ren, Su-Qi Zou*, Hai-Tao Wu*, Bing-Xing Pan*. Ablation of Lrp4 in Schwann Cells Promotes Peripheral Nerve Regeneration in Mice. Biology, 2021, 10:452.

7. Wen-Jie You#, Ye He#, Wei-Zhu Liu, Yu-Ge Zhu, Ping Hu, Bing-Xing Pan, Wen-Hua Zhang. Exposure to single prolonged stress fails to induce anxiety-like behavior in mice. Stress and Brain, 2021, 1(2):145-159.

8. Tao-Hui Liu, Ju Lu, Kacper Lukasiewicz, Bing-Xing Pan, Yi Zuo. Stress induces microglia-associated synaptic circuit alterations in the dorsomedial prefrontal cortex. Neurobiology of Stress, 2021, 15:100342.

9. Xia Qin, Xiao-Xuan Liu, Yu Wang, Dan Wang, Ying Song, Jia-Xin Zou, Han-Qing Pan, Xiao-Zhou Zhai, Yong-Mei Zhang, Yang-Bo Zhang, Ping Hu*, Wen-Hua Zhang*. Early life stress induces anxiety-like behavior during adulthood through dysregulation of neuronal plasticity in the basolateral amygdala. Life Sciences, 2021, 285:119959.

2020

1. Wen-Bing Chen#, Han-Qing Pan#, Ye He, Xue-Hui Wang, Wen-Hua Zhang, Bing-Xing Pan. Rap1b but not Rap1a in the forebrain is required for learned fear. Cell and Bioscience, 2020, 10:107.

2. Han-Qing Pan#, Wen-Hua Zhang#*, Cai-Zhi Liao, Ye He, Zhi-Ming Xiao, Xia-Qin, Wei-Zhu Liu, Na Wang, Jia-Xin Zou, Xiao-Xuan Liu, Bing-Xing Pan*. Chronic stress oppositely regulates tonic inhibition in Thy1-expressing and non-expressing neurons in amygdala. Frontiers in Neuroscience, 2020, 14:299.

3. Wei-Zhu Liu#, Wen-Hua Zhang#, Zhi-Heng Zheng, Jia-Xin Zou, Xiao-Xuan Liu, Shou-He Huang, Wen-Jie You, Ye He, Jun-Yu Zhang, Xiao-Dong Wang, Bing-Xing Pan. Identification of a prefrontal cortex-to-amygdala pathway for chronic stress-induced anxiety. Nature Communications, 2020, 11:2221.

4. Ren-Wen Han#*, Zhi-Peng Liu#, Hong-Ru Lin, Ao-Wen Tian, Yun-Fei Xiao, Jie Wei, Ke-Yu Deng, Bing-Xing Pan*, Hong-Bo Xin*. Role of Lateral Amygdala calstabin2 in Regulation of Fear Memory. Molecular Brain, 2020, 13(1):35.

5. Li-Guo Jin#, Ping Hu#, Yin-Yin Wang, Luo-Jia Wu, Kang Qin, Hao-Xin Cheng, Shu-Hua Wang, Bing-Xing Pan, Hong-Bo Xin, Wen-Hua Zhang*, Xiao-Lei Wang*. Fast-Acting Black-Phosphorus-Assisted Depression Therapy with Low Toxicity. Advanced Materials, 2020, 1906050.

6. Chi Wang#, Hui Liu#, Kun Li#, Zhen-Zhen Wu, Chen Wu, Jing-Ying Yu, Qian Gong, Ping Fang, Xing-Xing Wang, Shu-Min Duan, Hao Wang, Yan Gu, Ji Hu, Bing-Xing Pan, Mathias V. Schmidt, Yi-Jun Liu, Xiao-Dong Wang. Tactile modulation of memory and anxiety requires dentate granule cells along the dorsoventral axis. Nature Communications, 2020, 11:6045.

2019

1. Wen-Hua Zhang, Wei-Zhu Liu, Ye He, Wen-Jie You, Jun-Yu Zhang, Hong Xu, Xiao-Li Tian, Bao-Ming Li, Lin Mei, Andrew Holmes, Bing-Xing Pan. Chronic stress causes projection-specific adaptation of amygdala neurons via small-conductance calcium-activated potassium channel downregulation. Biological Psychiatry, 2019, 85:812-828. (Commentary by C. Morel, S. Montgomery, M.H Han, Small-Conductance, Calcium-Activated Potassium Channels: A Key Circuit Determinant for Stress-Induced Amygdala Dysfunction. Biological Psychiatry, 2019, 85:784-786)

2. Jun-Yu Zhang#, Tao-Hui Liu#, Ye He, Han-Qing Pan, Wen-Hua Zhang, Xiao-Li Tian, Xiao-Ping Yin, Bao-Ming Li, Xiao-Dong Wang, Andrew Holmes, Ti-Fei Yuan, Bing-Xing Pan. Chronic stress remodels synapses in an amygdala circuit-specific manner. Biological Psychiatry, 2019, 85:189-201. (Commentary by G. Treccani, From Structure to Behavior: Circuit Specificity of Stress-Induced Synaptic Plasticity in the Basolateral Amygdala Projection Neurons. Biological Psychiatry, 2019, 85:e7-e9.)

3. Wen-Hua Zhang, Ke-Xin Cao, Zeng-Bo Ding, Jian-Li Yang, Bing-Xing Pan*, Yan-Xue Xue*. Role of prefrontal cortex in extinction of drug memories. Psychopharmacology. 2019. 236: 463-477. (Invited Review)

4. Xia Qin, Ye He, Na Wang, Jia-Xin Zou, Yong-Mei Zhang, Jun-Li Cao, Bing-Xing Pan, Wen-Hua Zhang. Moderate maternal separation mitigates the altered synaptic transmission and neuronal activation in amygdala by chronic stress in adult mice. Molecular Brain, 2019, 12:111.

5. Ye He#, Zhi-Heng Zheng#, Jin Zhou, Wen-Jie You, Bing-Xing Pan, Wen-Hua Zhang. Gender-dependent regulation of anxiety-like behavior by delta-subunit containing GABAA receptor during postnatal development. Neuroreport. 2019. 30(11): 753-759.

6. Xiao-Bin Xu*, Shi-Jun Fan, Yuan-Qiao Guo, Ruei Tan, Jun-Yu Zhang, Wen-Hua Zhang, Bing-Xing Pan*, Nobumasa Kato. The effects of perinatal bisphenol A exposure on thyroid hormone homeostasis and glucose metabolism in prefrontal cortex and hippocampus of rats. Brain & Behavior. 2019. e01225. 

2018

1. Hong-Sheng Wang#, Fang  Liu#, Wen-Bing Chen#, Xiang-Dong Sun, Wan-Peng Cui, Zhao-Qi Dong, Kai Zhao, Er-Kang Fei, Bing-Xing Pan, Bao-Ming Li, Wen-Cheng Xiong, Lin Mei. Genetic recovery of ErB4 in adulthood partially restores brain function in null mice. Proc. Natl. Acad. Sci. USA. 2018. 115(51):13105-13110.

2. Wei-Zhu Liu, Bo-Wei Huang, Wen-JieYou, Ping Hu, Xue-Hui Wang, Jun-Yu Zhang, Xiao-Bin Xu, Zong-Yong Zhang, Bing-Xing Pan, Wen-Hua Zhang. Harmine enhances GABAergic transmission onto basoamygdala projection neurons in mice. Brain Research Bulletin. 2018, 137: 294-300.

3. Chun Song, Han Yan, Han-Ming Wang, Yan Zhang, Hui-Qing Cao, Yi-Qi Wan, Ling-Bao Kong, Sheng-Han Chen, Hong Xu, Bing-Xing Pan, Jin Zhang, Guo-Huang Fan, Hong-Bo Xin, Zi-Cai Liang, Wei-Ping Jia, Xiao-Li Tian. AQR is a novel type 2 diabetes-associated gene that regulates signaling pathways critical for glucose metabolism. Journal of Genetics and Genomics. 2018. 45: 111-120.

4. Ya-Nan Wang#, Dwight Figueiredo#, Xiang-Dong Sun#, Zhao-Qi Dong, Wen-Bing Chen, Wan-Peng Cui, Fang Liu, Hong-Sheng Wang, Hai-Wen Li, Heath Robinson, Er-Kang Fei, Bing-Xing Pan, Bao-Ming Li, Wen-Cheng Xiong, Lin Mei. Controlling of glutamate release by neuregulin3 via inhibiting the assembly of the SNARE complex. Proc. Natl. Acad. Sci. USA. 2018.115(10): 2508-2513.

5.  Zhi-Zhi Liu, Zi-Long Wang, Tae-Ik Choi, Wen-Ting Huang, Han-Tsing Wang, Ying-Ying Han, Lou-Yin Zhu, Hyun-Taek Kim, Jung-Hwa Choi, Jin-Soo Lee, Hyung-Goo Kim, Jian Zhao, Yue Chen, Zhuo Lu, Xiao-Li Tian, Bing-Xing Pan, Bao-Ming Li, Cheol-Hee Kim*, Hong Xu*. Chd7 Is Critical for Early T-Cell Development and Thymus Organogenesis in Zebrafish. American Journal of Pathology.  2018, 188(4): 1043-1058.

6. Jin-Qiong Zhan#, Li-Li Zheng#, Hai-Bo Chen, Bin Yu, Wei Wang, Ting Wang, Bo Ruan, Bin-Xing Pan, Juan-Ru Chen, Xue-Fen Li, Bo Wei*, Yuan-Jian Yang*. Hydrogen Sulfide Reverses Aging-Associated Amygdalar Synaptic Plasticity and Fear Memory Deficits in Rats. Frontiers in Neuroscience. 2018,12:390.

2017

1. Zhi-Peng Liu#, Qing-Hai He#, Han-Qing Pan, Jin Zhou, Ye He, Xiao-Bin Xu, Xiao-Ping Yin, Bao-Ming Li, Tian-Ming Gao*, Bing-Xing Pan*. Delta subunit containing GABAA receptors disinhibit lateral amygdala and facilitate fear learning in mice. Biological Psychiatry. 2017, 81(12): 990-1002.

2. Xiao-Bin Xu*, Shi-Jun Fan, Ye He, Wen-Hua Zhang, Bing-Xing Pan*. Loss of hippocampal oligodendrocytes contributes to the deficit of contextual fear conditioning in adult rats experiencing early bisphenol A exposure. Molecular Neurobiology. 2017, 54(6):4524-4536.

3. Chen Song, Wen-Hua Zhang, Xue-Hui Wang, Jun-Yu Zhang, Xiao-Li Tian, Xiao-Ping Yin, Bing-Xing Pan*. Acute stress enhances the glutamatergic transmission onto basoamygdala neurons embedded in distinct microcircuits. Molecular Brain. 2017, 10: 3.

4. Wen-Hua Zhang, Jin Zhou, Han-Qing Pan, Xue-Hui Wang, Wei-Zhu Liu, Jun-Yu Zhang, Xiao-Ping Yin, Bing-Xing Pan. δ Subunit-containing GABAA receptor prevents overgeneralization of fear in adult mice. Learning & Memory. 2017, 24(8):381-384.

2016及以前

1. Ping Hu, Jing-jing He, Shi-Ling Liu, Meng Wang, Bing-Xing Pan, Wen-Hua Zhang. β2-adrenergic receptor activation promotes the proliferation of A549 lung cancer cells via the ERK1/2/CREB pathway. Oncology Report. 2016, 36(3): 1757-63.

2. Xiao-Bin Xu*, Ye He, Chen Song, Xin Ke, Shi-Jun Fan, Wei-Jie Peng, Ruei Tan Mitsuhiro Kawata, Ken-Ichi Matsuda, Bing-Xing Pan*, Nobumasa Kato. Bisphenol A regulates the estrogen receptor alpha signaling in developing hippocampus of male rats through estrogen receptor. Hippocampus. 2014, 24(12):1570-1580.

3. Zhi-Peng, Liu, Chen Song, Min Wang, Ye He, Xiao-Bin Xu, Han-Qing Pan, Wen-Bing Chen, Wei-Jie Peng, Bing-Xing Pan. Chronic stress impairs GABAergic control of amygdala through suppressing the tonic GABAA receptor currents. Molecular Brain. 2014, 7(1): 32. (Highly Accessed Paper)

4. Chen Song, Xiao-Bin Xu, Ye He, Zhi-Peng Liu, Bing-Xing Pan. Stuttering interneurons generate fast and robust inhibition onto projection neurons with low capacity of short term modulation in mouse lateral amygdala. PLOS ONE. 2013, 8(3):e60154

5. Bing-Xing Pan*, Yulin Dong, Wataru Ito, Yuchio Yanagawa, Ryuichi Shigemoto, Alexei Morozov*. Selective gating of glutamatergic transmission to excitatory neurons of amygdala by presynaptic GABAb receptors. Neuron. 2009, 61(6): 917-929 (with preview in the same issue)

6. Bing-Xing Pan, Wataru Ito, Alexei Morozov. Physiological divergence between thalamic and cortical inputs to lateral amygdala during the juvenile-adult transition in mice. Biological Psychiatry. 2009, 66: 964-971. (With press release in www.sciencedaily.com)

7. Wataru Ito, Bing-Xing Pan, Alexei Morozov. Enhanced generalization of auditory conditioned fear in juvenile mice. Learning & Memory. 2009, 16(3): 187-92.

8. Bing-Xing Pan, Francois Vautier, Wataru Ito, Vadim Balshakov, Alexei Morozov. Enhanced cortico-amygdala efficacy and suppressed fear in absence of Rap1. Journal of Neuroscience. 2008, 28(9): 2089-2098.