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87Su S, Quan C, Chen Q, Wang R, Du Q, Zhu S, Li M, Yang X, Rong P, Chen J, Bai Y, Zheng W, Feng W, Liu M, Xie B, Ouyang K, Shi YS, Lan F, Zhang X, Xiao R, Chen X, Wang HY, Chen S. (2024) AS160 is a lipid-responsive regulator of cardiac Ca2+ homeostasis by controlling lysophosphatidylinositol metabolism and signaling. Nat Commun. 15(1): 9602. doi: 10.1038/s41467-024-54031-5. 

86. Wang H*, Zhao B*, Huang L*, Zhu X, Li N, Huang C, Han Z#, Ouyang K#. (2024) Conditional deletion of IP3R1 by Islet1-Cre in mice reveals a critical role of IP3R1 in interstitial cells of Cajal in regulating GI motility. J Gastroenterol. doi: 10.1007/s00535-024-02164-1. Online ahead of print.

85. Zhang T, Bi C, Li Y, Zhao L, Cui Y, Ouyang K#, Xiao B#. (2024). Phosphorylation of Piezo1 at a single residue, serine-1612, regulates its mechanosensitivity and in vivo mechanotransduction function. Neuron. doi.org/10.1016/j.neuron.2024.08.009

84. Zhu S*, Chen Z*, Liu C, Duong J, Tran T, Liang Z, Fang X#, Ouyang K#. (2024). The essential role of MED27 in stabilizing the mediator complex for cardiac development and function. Life Sci. 123020. doi: 10.1016/j.lfs.2024.123020. Online ahead of print.

83. Huang C*, Luo P*, Zhu X*, Li N, Ouyang K#, Lu Q#, Han Z#. (2024) Causal effect of obesity and adiposity distribution on the risk of pressure ulcers and potential mediation by type 2 diabetes mellitus: insights from multivariable mendelian randomization and mediation analysis. Arch Dermatol Res. 316(8):550. doi: 10.1007/s00403-024-03299-0.

82. Huang F*, Zhang F*, Huang L*, Zhu X, Huang C, Li N, Da Q, Huang Y, Yang H, Wang H, Zhao L, Lin Q, Chen Z, Xu J, Liu J, Ren M, Wang Y#, Han Z#, Ouyang K#. (2024). Inositol 1,4,5-Trisphosphate Receptors Regulate Vascular Smooth Muscle Cell Proliferation and Neointima Formation in Mice. J Am Heart Assoc. e034203. doi: 10.1161/JAHA.124.034203. Online ahead of print.

81. Meng L, Dong R, Mi W, Qin K, Ouyang K#, Sun J#, Li J#. (2024). The ubiquitin E3 ligase APC/CCdc20 mediates mitotic degradation of OGT. J Biol Chem. 107448. doi: 10.1016/j.jbc.2024.107448. 

80. Yan M, Gao J, Lan M, Wang Q, Cao Y, Zheng Y, Yang Y, Li W, Yu X, Huang X, Dou L, Liu B, Liu J, Cheng H, Ouyang K, Xu K, Sun S, Liu J, Tang W, Zhang X, Man Y, Sun L, Cai J, He Q, Tang F, Li J, Shen T. (2024). DEAD-box helicase 17 (DDX17) protects cardiac function by promoting mitochondrial homeostasis in heart failure. Signal Transduct Target Ther. 9(1): 127. doi: 10.1038/s41392-024-01831-2.

79. Xu J, Liu Z, Yang Q, Ma Q, Zhou Y, Cai Y, Zhao D, Zhao G, Lu T, Ouyang K, Hong M, Kim HW, Shi H, Zhang J, Fulton D, Miller C, Malhotra R, Weintraub NL, Huo Y. (2024) Adenosine kinase inhibition protects mice from abdominal aortic aneurysm via epigenetic modulation of VSMC inflammation. Cardiovasc Res. cvae093. doi: 10.1093/cvr/cvae093. Online ahead of print.

78. Yuan W, Lin H, Sun Y, Liu L, Yan M, Song Y, Zhang X, Lu X, Xu Y, He Q, Ouyang K, Zhang C, Pan Y, Huang Y, Li Y, Lu X, Liu J. (2024) Myocardin reverses insulin resistance and ameliorates cardiomyopathy by increasing IRS-1 expression in a murine model of lipodystrophy caused by adipose deficiency of vacuolar H+-ATPase V0d1 subunit. Theranostics. 14(5): 2246-2264. doi: 10.7150/thno.93192. eCollection 2024.

77. Jiang Z, Huang C, Guo E, Zhu X, Li N, Huang Y, Wang P, Shan H, Yin Y, Wang H, Huang L, Han Z, Ouyang K#, Sun L#. (2024) Platelet-Rich Plasma in Young and Elderly Humans Exhibits a Different Proteomic Profile. J Proteome Res. doi: 10.1021/acs.jproteome. 4c00030.

76. Shen T, Wang S, Huang C, Zhu S, Zhu X, Li N, Wang H, Huang L, Ren M, Han Z, Ge J#, Chen Z#Ouyang K#. (2024) Cardiac-specific deletion of heat shock protein 60 induces mitochondrial stress and disrupts heart development in mice. Biochem Biophys Res Commun. 710:149883. doi: 10.1016/j.bbrc.2024.149883.

75. Chen Z, Pan Z, Huang C, Zhu X, Li N, Huynh H, Xu J, Huang L, Vaz FM, Liu J, Han Z#, Ouyang K#. (2024). Cardiac lipidomic profiles in mice undergo changes from fetus to adult. Life Sci. 2:122484. doi: 10.1016/j.lfs.2024.122484. Online ahead of print.

74. Qi X, Wang S, Qiu L, Chen X, Huang Q, Ouyang K, Chen Y. (2023) Transient ischemic attack and coronary artery disease: a two-sample Mendelian randomization analysis. Front Cardiovasc Med. 10:1192664. doi: 10.3389/fcvm.2023.1192664. 

73. Fan X, Xie R, Song W, Ouyang K, Ren L. (2023) Biomimetic Hyaluronic Acid-Based Brush Polymers Modulate Chondrocyte Homeostasis via ROS/Ca2+/TRPV4. Biomacromolecules. doi: 10.1021/acs.biomac.3c00547. Online ahead of print.

72. Da Q, Huang L, Huang C, Chen Z, Jiang Z, Huang F, Shen T, Sun L, Yan Z, Ye X, Yi J, Huang Y, Da J, Ren M, Liu J, Wang T, Han Z#, Ouyang K#. (2023) Glycolytic regulatory enzyme PFKFB3 as a prognostic and tumor microenvironment biomarker in human cancers. Aging (Albany NY). 15. doi: 10.18632/aging.204758. 

71. Qi X, Qiu L, Wang S, Chen X, Huang Q, Zhao Y, Ouyang K, Chen Y. (2023) Non-thyroidal illness syndrome and the prognosis of heart failure: a systematic review and meta-analysis. Endocr Connect. doi: 10.1530/EC-23-0048.

70. Gu M, Zhao Y, Wang H, Cheng W, Liu J, Ouyang K, Wei C. (2023) Suppression of RBFox2 by Multiple MiRNAs in Pressure Overload-Induced Heart Failure. Int J Mol Sci. 24(2):1283. doi: 10.3390/ijms24021283.

69. Huynh H, Zhu S, Lee S, Bao Y, Pang J, Nguyen A, Gu Y, Chen C, Ouyang K, Evans SM, Fang X. (2023) DELE1 is protective for mitochondrial cardiomyopathy. J Mol Cell Cardiol. 175: 44-48. doi: 10.1016/j.yjmcc.2022.12.003.

68. Jiang Z, Shen T, Huynh H, Fang X, Han Z#, Ouyang K#. (2022) Cardiolipin Regulates Mitochondrial Ultrastructure and Function in Mammalian Cells. Genes. 13, 1889. Doi: 10.3390/genes13101889. 

67. Zhu S, Nguyen A, Pang J, Zhao J, Chen Z, Liang Z, Gu Y, Huynh H, Bao Y, Lee S, Kluger Y, Ouyang K, Evans SM, Fang X. (2022) Mitochondrial Stress Induces an HRI-eIF2α Pathway Protective for Cardiomyopathy. Circulation. 146(13): 1028-1031. doi: 10.1161/CIRCULATIONAHA.122.059594.

66. Tang H#, Li Y, Wang S, Ji J, Zhu X, Bao Y, Huang C, Luo Y, Huang L, Gao Y, Wei C, Liu J, Fang X, Sun L#, Ouyang K#. (2022) IP3R-mediated Ca2+ signaling controls B cell proliferation through metabolic reprogramming. iScience. 25(5):104209. doi: 10.1016/j.isci.2022.104209.

65. Da Q, Ren M, Huang L, Qu J, Yang Q, Xu J, Ma Q, Mao X, Cai Y, Zhao D, Luo J, Yan Z, Sun L, Ouyang K, Zhang X, Han Z, Liu J, Wang T. (2022) Identification and Validation of a Ferroptosis-Related Signature for Predicting Prognosis and Immune Microenvironment in Papillary Renal Cell Carcinoma. Int J Gen Med. 2022 15: 2963-2977. doi: 10.2147/IJGM.S354882. eCollection 2022.

64. Tan C, Zhu S, Chen Z, Liu C, Li YE, Zhu M, Zhang Z, Zhang Z, Zhang L, Gu Y, Liang Z, Boyer TG, Ouyang K, Evans SM, Fang X. (2021) Mediator complex proximal Tail subunit MED30 is critical for Mediator core stability and cardiomyocyte transcriptional network. PLoS Genet. 17(9): e1009785. doi: 10.1371/journal.pgen.1009785.

63. Chen Z, Zhu S, Wang H, Wang L, Zhang J, Gu Y, Tan C, Dhanani M, Wever E, Wang X, Xie B, Wang S, Huang L, van Kampen A, Liu J, Han Z, Patel H, Vaz F, Fang X#, Chen J#, Ouyang K#. (2021) PTPMT1 Is Required for Embryonic Cardiac Cardiolipin Biosynthesis to Regulate Mitochondrial Morphogenesis and Heart Development. Circulation. DOI: 10.1161 / CIRCULATIONAHA.121.054768. 

62. Siting Zhu, Ze’e Chen, Mason Zhu, Ying Shen, Leonardo J. Leon, Liguo Chi, Simone Spinozzi, Changming Tan, Yusu Gu, Anh Nguyen, Yi Zhou, Wei Feng, Frédéric M. Vaz, Xiaohong Wang, Asa B. Gustafsson, Sylvia M. Evans, Ouyang Kunfu#, Xi Fang#. (2021) Cardiolipin Remodeling Defects Impair Mitochondrial Architecture and Function in a Murine Model of Barth Syndrome Cardiomyopathy. Circ Heart Fail. 14(6): e008289. (#co-corresponding author)

61. Li Y, Dong M, Wang Q, Kumar S, Zhang R, Cheng W, Xiang J, Wang G, Ouyang K, Zhou R, Xie Y, Lu Y, Yi J, Duan H, Liu J. (2021) HIMF deletion ameliorates acute myocardial ischemic injury by promoting macrophage transformation to reparative subtype. Basic Res Cardiol. 116(1): 30. doi: 10.1007/s00395-021-00867-7.

60.     Wang S, Wu X, Zhang Y, Zhang D, Xie B, Pan Z, Ouyang K, Peng T. (2021) Discovery of a highly efficient nitroaryl group for detection of nitroreductase and imaging of hypoxic tumor cells. Org. Biomol. Chem. 19(15): 3469-3478. doi: 10.1039/d1ob00356a.

59.     Li Y, Tang H#, Chen F, Chen J, Wang H, Chen Z, Duan Y, Wang X, Li L#, Ouyang K#. (2021) SETD2 is essential for terminal differentiation of erythroblasts during fetal erythropoiesis. Biochem Biophys Res Commun. 552:98-105. doi: 10.1016/j.bbrc.2021.03.040.

58.     Chen F, Chen J, Wang H, Tang H, Huang L, Wang S, Wang X, Fang F, Liu J, Li L#, Ouyang K#, Han Z#. (2021) Histone lysine methyltransferase SETD2 regulates coronary vascular development in embryonic mouse hearts. Front Cell Dev Biol. 9: 651655.doi: 10.3389/fcell.2021.651655. (#co-corresponding author)

57.     Chen Z, Huang L, Tso A, Wang S, Fang X, Ouyang K#, Han Z#. (2021) Mitochondrial chaperones and proteases in cardiomyocytes and heart failure. Front Mol Biosci. 8: 630332. doi: 10.3389/fmolb.2021.630332. (#co-corresponding author)

56.     Chen Z, Duan Y, Wang H, Tang H, Wang S, Wang X, Liu J, Fang X#, Ouyang K#. (2021) Atypical protein kinase C is essential for embryonic vascular development in mice. Genesis. e23412. doi: 10.1002/dvg.23412.

55.     Zhang P, Huang JJ, Ou-Yang KF, Liang H, Li ML, Wang YJ, Yang HT. (2020). Minimal contribution of IP3R2 in cardiac differentiation and derived ventricular-like myocytes from human embryonic stem cells. Acta Pharmacol Sin. doi: 10.1038/s41401-020-00528-w.

54.     Liu C, Spinozzi S, Feng W, Chen Z, Zhang L, Zhu S, Wu T, Fang X, Ouyang K, Evans SM, Chen J. (2020) Homozygous G650del nexilin variant causes cardiomyopathy in mice. JCI Insight. 5(16):138780. doi: 10.1172/jci.insight.138780.

53.     Dong Y, Lee Y, Cui K, He M, Wang B, Bhattacharjee S, Zhu B, Yago T, Zhang K, Deng L, Ouyang K, Wen A, Cowan DB, Song K, Yu L, Brophy ML, Liu X, Wylie-Sears J, Wu H, Wong S, Cui G, Kawashima Y, Matsumoto H, Kodera Y, Wojcikiewicz RJH, Srivastava S, Bischoff J, Wang DZ, Ley K, Chen H. (2020) Epsin-mediated degradation of IP3R1 fuels atherosclerosis. Nat Commun. 11(1):3984. doi: 10.1038/s41467-020-17848-4.

52.  Spinozzi S, Liu C, Chen Z, Feng W, Zhang L, Ouyang K, Evans SM, Chen J. (2020) Nexilin Is Necessary for Maintaining the Transverse-Axial Tubular System in Adult Cardiomyocytes. Circ Heart Fail. doi: 10.1161/CIRCHEARTFAILURE.120.006935.

51.  Quan C, Du Q, Li M, Wang R, Ouyang Q, Su S, Zhu S, Chen Q, Sheng S, Chen L, Wang H, Campbell DG, MacKintosh C, Yang Z, Ouyang K, Wang HY, Chen S. (2020) A PKB-SPEG signaling nexus links insulin resistance with diabetic cardiomyopathy by regulating calcium homeostasis. Nat Commun. 11(1):2186. doi: 10.1038/s41467-020-16116-9.

50.  Duan Y, Tang H, Mitchell-silbaugh K, Fang X, Han Z#, Ouyang K#. (2020) Heat shock protein 60 in cardiovascular physiology and diseases. Front Mol Biosci. 7: 73. Doi: 10.3389/fmolb.2020.00073. 

49.  Yang F, Huang L, Tso A, Wang H, Cui L, Lin L, Wang H, Ren M, Fang X, Liu J, Han Z#, Chen J#, Ouyang K#. (2020) Inositol 1,4,5-trisphosphate receptors are essential for fetal-maternal connection and embryo viability. Plos Genetics. 16(4): e1008739. doi: 10.1371/journal.pgen.1008739.

48.  Duan Y, Wang H, Mitchell-silbaugh K, Cai S, Fan F, Li Y, Tang H, Wang G, Fang X, Liu J, Jia N, Jing R#, Ouyang K#. (2019) Heat shock protein 60 regulates yolk sac erythropoiesis in mice. Cell Death Dis. 10: 766. doi: 10.1038/s41419-019-2014-2.

47.  Pinto-Duarte A, Roberts AJ, Ouyang K, Sejnowski TJ. (2019) Impairments in remote memory caused by the lack of Type 2 IP3 receptors. Glia. 67(10):1976-1989. doi: 10.1002/glia.23679.

46.  Fan F, Duan Y, Yang F, Trexler C, Wang H, Huang L, Li Y, Tang H, Wang G, Fang X, Liu J, Jia N, Chen J#, Ouyang K#. (2020) Deletion of heat shock protein 60 in adult mouse cardiomyocytes perturbs mitochondrial protein homeostasis and causes heart failure. Cell Death Diff. 27(2):587-600. doi: 10.1038/s41418-019-0374-x.

45.  Liu C, Spinozzi S, Chen JY, Fang X, Feng W, Perkins G, Cattaneo P, Guimarães-Camboa N, Dalton ND, Peterson KL, Wu T, Ouyang K, Fu XD, Evans SM, Chen J. (2019) Nexilin is a New Component of Junctional Membrane Complexes Required for Cardiac T-Tubule Formation. Circulation. doi: 10.1161/CIRCULATIONAHA.119.039751. [Epub ahead of print]

44.  Zhang Y, Ouyang K, Lipina TV, Wang H, Zhou Q. (2019) Conditioned stimulus presentations alter anxiety level in fear-conditioned mice. Mol Brain. 12(1): 28. doi: 10.1186/s13041-019-0445-4.

43.  Kumar S, Wang G, Zheng N, Cheng W, Ouyang K, Lin H, Liao Y, Liu J. (2019) HIMF (Hypoxia-Induced Mitogenic Factor)-IL (Interleukin)-6 Signaling Mediates Cardiomyocyte-Fibroblast Crosstalk to Promote Cardiac Hypertrophy and Fibrosis. Hypertension. 73(5):1058-1070.

42.  Lin Q, Zhao L, Jing R, Trexler C, Wang H, Li Y, Tang H, Huang F, Zhang F, Fang X, Liu J, Jia N, Chen J#, Ouyang K#. (2019) IP3Rs in endothelial cells play an essential role in vasodilation and blood pressure regulation. J Am Heart Assoc. 8(4): e011704. doi: 10.1161/JAHA.118.011704.

41.  Quan C, Li M, Du Q, Chen Q, Wang H, Campbell DG, Fang L, Xue B, MacKintosh C, Gao X, Ouyang K, Wang HY, Chen S. (2019) SPEG Controls Calcium Re-Uptake into the Sarcoplasmic Reticulum Through Regulating SERCA2a by Its Second Kinase-Domain. Circ Res. 124(5): 712-726. doi: 10.1161/CIRCRESAHA.118.313916.

40.  Fang X, Bogomolovas J, Zhou P, Mu Y, Ma X, Chen Z, Zhang L, Zhu M, Veevers J, Ouyang K, Chen J. (2019) P209L Mutation in BAG3 Does Not Cause Cardiomyopathy in Mice. Am J Physiol Heart Circ Physiol. 316(2):H392-H399. doi: 10.1152/ajpheart.00714.2018.

39.  Wang H, Jing R, Trexler C, Li Y, Tang H, Pan Z, Zhu S, Zhao B, Fang X, Liu J, Chen J#, Ouyang K#. (2019) Deletion of IP3R1 by Pdgfrb-Cre in mice results in intestinal pseudo-obstruction and lethality. J Gastroenterol. 54(5):407-418. doi: 10.1007/s00535-018-1522-7.

38.  Veevers J, Farah EN, Corselli M, Witty AD, Palomares K, Vidal JG, Emre N, Carson CT, Ouyang K, Liu C, van Vliet P, Zhu M, Hegarty JM, Deacon DC, Grinstein JD, Dirschinger RJ, Frazer KA, Adler ED, Knowlton KU, Chi NC, Martin JC, Chen J, Evans SM. (2018) Cell-Surface Marker Signature for Enrichment of Ventricular Cardiomyocytes Derived from Human Embryonic Stem Cells. Stem Cell Reports. 11: 1-14; doi: 10.1016/j.stemcr.2018.07.007.

37.  Xiao Y, Wang C, Chen JY, Lu F, Wang J, Hou N, Hu X, Zeng F, Ma D, Sun X, Ding Y, Zhang Y, Zheng W, Liu Y, Shang H, Zhu W, Han C, Zhang Y, Ouyang K, Chen L, Chen J, Xiao RP, Li CY, Zhang X. (2018) Deficiency of PRKD2 triggers hyperinsulinemia and metabolic disorders. Nat Commun. 9(1): 2015. doi: 10.1038/s41467-018-04352-z.

36.  Fang X, Bogomolovas J, Wu T, Zhang W, Liu C, Veevers J, Stroud MJ, Zhang Z, Ma X, Mu Y, Lao DH, Dalton ND, Gu Y, Wang C, Wang M, Liang Y, Lange S, Ouyang K, Peterson KL, Evans SM, Chen J. (2017). Loss-of-function mutations in co-chaperone BAG3 destabilize small HSPs and cause cardiomyopathy. J Clin Invest. 127(8): 3189-3200.

35.  Tang H, Wang H, Lin Q, Fan F, Zhang F, Peng X, Fang X, Liu J, Ouyang K. (2017) Loss of IP3 Receptor–Mediated Ca2+ Release in Mouse B Cells Results in Abnormal B Cell Development and Function. J Immunol. 199 (2): 570-580; DOI: https://doi.org/10.4049/jimmunol.1700109

34.  Wang YJ, Huang J, Liu W, Kou X, Tang H, Wang H, Gao S, Ouyang K, Yang H-T. (2017) IP3R-Mediated Ca2+ Signals Govern Hematopoietic and Cardiac Divergence of Flk1+ Cells via the Calcineurin-NFATc3-Etv2 Pathway. J Mol Cell Biol. 9(4):274-288; doi: 10.1093/jmcb/mjx014. [Epub ahead of print]

33.  Lin Q, Zhao G, Fang X, Peng X, Tang H, Wang H, Jing R, Liu J, Lederer WJ, Chen J#, Ouyang K#. (2016) IP3 receptors regulate vascular smooth muscle contractility and hypertension. JCI Insight. 1(17): e89402. doi: 10.1172/jci.insight. 89402.

32.  Fang X, Stroud MJ, Ouyang K, Fang L, Zhang J, Dalton ND, Gu Y, Wu T, Peterson KL, Huang HD, Chen J, Wang N. (2016) Adipocyte-specific loss of PPARγ attenuates cardiac hypertrophy. JCI Insight. 1(16): e89908. doi: 10.1172/jci.insight.89908.

31.  Huang J, Zhang M, Zhang P, Liang H, Ouyang K, Yang HT. (2016) Coupling switch of P2Y-IP3 receptors mediates differential Ca2+ signaling in human embryonic stem cells and derived cardiovascular progenitor cells. Purinergic Signal. 12(3):465-78

30.  Wei C, Qiu J, Zhou Y, Xue Y, Hu J, Ouyang K, Banerjee I, Zhang C, Chen B, Li H, Chen J, Song LS, Fu XD. (2015) Repression of the Central Splicing Regulator RBFox2 Is Functionally Linked to Pressure Overload-Induced Heart Failure. Cell Rep. pii: S2211-1247(15)00141-2. doi: 10.1016/j.celrep.2015.02.013.

29.  Hashem SI, Perry CN, Bauer M, Han S, Clegg SD, Ouyang K, Deacon DC, Spinharney M, Panopoulos AD, Belmonte JC, Frazer KA, Chen J, Gong Q, Zhou Z, Chi NC, Adler ED. (2015) Oxidative Stress Mediates Cardiomyocyte Apoptosis in a Human Model of Danon Disease and Heart Failure. Stem Cells. 33(7):2343-50. doi: 10.1002/stem.2015.

28.  Mu Y, Jing R, Peter AK, Lange S, Lin L, Zhang J, Ouyang K, Fang X, Veevers J, Zhou X, Evans SM, Cheng H, Chen J. (2015) Cypher and Enigma Homolog Protein Are Essential for Cardiac Development and Embryonic Survival. J Am Heart Assoc 4: e001950 doi: 10.1161/JAHA.115.001950.

27.  Zhang Z, Stroud MJ, Zhang J, Fang X, Ouyang K, Kimura K, Mu Y, Dalton ND, Gu Y, Bradford WH, Peterson KL, Cheng H, Zhou X, Chen J. (2015) Normalization of Naxos plakoglobin levels restores cardiac function in mice. J. Clin. Invest. 125(4):1708–1712. doi:10.1172/JCI80335

26.  Ouyang K*, Gomez-Amaro R*, Stachura D*, Tang H, Peng X, Fang X, Traver D, Evans SM, Chen J. (2014) Loss of IP3R-mediated Ca2+ signaling in thymocytes leads to aberrant development and acute lymphoblastic leukemia. Nat. Commun. doi: 10.1038/ncomm5814. (*, Co-first author).

25.  Chapman MA, Zhang J, Banerjee I, Guo LT, Zhang Z, Shelton GD, Ouyang K, Lieber RL, Chen J. (2014) Disruption of both nesprin 1 and desmin results in nuclear anchorage defects and fibrosis in skeletal muscle. Hum Mol Genet. 23(22): 5879-92.

24.  Banerjee I, Zhang J, Moore-Morris T, Pfeiffer E, Buchholz KS, Liu A, Ouyang K, Stroud MJ, Gerace L, Evans SM, McCulloch A, Chen J. (2014) Targeted ablation of nesprin 1 and nesprin 2 from murine myocardium results in cardiomyopathy, altered nuclear morphology and inhibition of the biomechanical gene response. PLoS Genet. 10(2):e1004114.

23.  Lyon RC, Mezzano V, Wright AT, Pfeiffer E, Chuang J, Banares K, Castaneda A, Ouyang K, Cui L, Contu R, Gu Y, Evans SM, Omens JH, Peterson KL, McCulloch AD, Sheikh F. (2014) Connexin defects underlie arrhythmogenic right ventricular cardiomyopathy in a novel mouse model. Hum Mol Genet. 23(5):1134-50

22.  Xiang SY, Ouyang K, Yung BS, Miyamoto S, Smrcka AV, Chen J, Brown JH. (2013) PLCe, PKD1, and SSH1L Transduce RhoA Signaling to Protect Mitochondria from Oxidative Stress in the Heart. Sci Signal. 6 (306): 1-11

21.  Lin C, Guo X, Lange S, Liu J, Ouyang K, Yin X, Jiang L, Cai Y, Mu Y, Sheikh F, Ye S, Chen J, Ke Y, Cheng H.(2013) Cypher/ZASP is a novel A kinase anchoring protein. J Biol Chem. 288 (41): 29403–29413.

20.  Zhang R, Han P, Yang H, Ouyang K, Lee K, Lin Y, Ocorr K, Kang G, Chen J, Stainier D, Yelon D, Chi NC. (2013) In Vivo Cardiac Reprogramming Contributes to Zebrafish Heart Regeneration. Nature 498: 497–501

19.  Cooley N*, Ouyang K*, McMullen JR, Sadoshima J, Kiriasis H, Wu W, Mu Y, Du X, Chen J, Woodcock EA. (2013) No contribution of IP3-R(2) to disease phenotype in models of dilated cardiomyopathy or pressure overload hypertrophy. Circulation: Heart Failure 6: 318-325. (*, Co-first author).

18.  Xue Y, Ouyang K, Huang J, Zhou Y, Ouyang H, Li H, Wang G, Wu Q, Wei C, Bi Y, Jiang L, Cai Z, Sun H, Zhang K, Zhang Y, Chen J, Fu X. (2013) Direct Conversion of Fibroblasts to Neurons by Reprogramming PTB-Regulated microRNA Circuits. Cell 152: 82–96.

17.  Wang Y, Li G, Goode J, Paz JC, Ouyang K, Screaton R, Fischer WH, Chen J, Tabas I, Montminy M. (2012) InsP3 receptor regulates hepatic gluconeogenesis in fasting and diabetes. Nature 485: 128-132.

16.  Sheikh F*, Ouyang K*, Campbell S*, Lyon R, Chuang J, Fitzsimons D, Tangney J, Hidalgo C, Chung C, Cheng H, Dalton ND, Gu Y, Kasahara H, Ghassemian M, Omens J, Peterson K, Granzier H, Moss R, McCulloch AD and Chen J. (2012) Mouse and computational models link Mlc2v dephosphorylation to altered myosin kinetics in early cardiac disease. J. Clin. Invest. 122(4): 1209-1221. (*, Co-first author).

15.  Fang H, Chen M, Ding Y, Shang W, Zhang X, Xu J, Zhang W, Li K, Xiao Y, Gao F, Shang S, Li J, Tian X, Wang S, Zhou J, Weisleder N, Ma J, Ouyang K, Chen J, Wang X, Zheng M, Wang W, Zhang X, Cheng H. (2011) Imaging superoxide flash and metabolism-coupled mitochondrial permeability transition in living animals Cell Research 21: 1295-1304.

14.  Cheng H, Zheng M, Peter AK, Kimura K, Li X, Ouyang K, Shen T, Cui L, Frank D, Dalton ND, Gu Y, Frey N, Peterson KL, Evans SM, Knowlton KU, Sheikh F, Chen J. (2011) Selective deletion of long but not short Cypher isoforms leads to late onset dilated cardiomyopathy. Hum. Mol. Genet. 20: 1751-62.

13.  Jem A. Efe, Simon Hilcove, Janghwan Kim, Hongyan Zhou, Kunfu Ouyang, Gang Wang, Ju Chen, Sheng Ding (2011) Conversion of mouse fibroblasts into cardiomyocytes using a direct reprogramming strategy. Nat. Cell Biol. 13: 215-222.

12.  Guiling Zhao, Zachary Neeb, M. Dennis Leo, Judith Pachuau, Adebowale Adebiyi, Kunfu Ouyang, Ju Chen, Jonathan H. Jaggar (2010) Type 1 IP3 receptors activate BKCa channels via local molecular coupling in cerebral artery smooth muscle cells. J. Gen. Physiol. 136:283-291.

11.    Hongqiang Cheng, Kensuke Kimura, Angela K. Peter, Li Cui, Kunfu Ouyang, Tao Shen, Yujie Liu, Yusu Gu, Nancy D. Dalton, Sylvia M. Evans, Kirk U. Knowlton, Kirk L. Peterson, Ju Chen (2010) Loss of Enigma homolog protein results in dilated cardiomyopathy. Circ. Res. 107: 348-356.

10.  Wei C, Wang X, Chen M, Ouyang K, Zheng M, Cheng H. (2010). Flickering calcium microdomains signal turning of migrating cells. Can. J. Physiol. Pharmacol. 88: 105-110. (Review)

9.    Stephan Lange*, Kunfu Ouyang*, Gretchen Meyer, Li Cui, Hongqiang Cheng, Richard L. Lieber, Ju Chen (2009) Obscurin regulates longitudinal SR architecture. J. Cell. Sci. 122: 2640-2650 (*, Co-first Author).

8.    Chaoliang Wei, Xianhua Wang, Min Chen, Kunfu Ouyang, Long-Sheng Song, Heping Cheng (2009) Calcium flickers steer cell migration. Nature 457: 901-905.

7.    Ming Zheng, Hongqiang Cheng, Xiaodong Li, Jianlin Zhang, Li Cui, Kunfu Ouyang, Liang Han, Ting Zhao, Yusu Gu, Nancy D. Dalton, Marie-Louise Bang, Kirk L. Peterson, Ju Chen (2009) Cardiac-specific ablation of cypher leads to a severe form of dilated cardiomyopathy with premature death. Hum. Mol. Genet. 18: 701-713.

6.    Wang Wang, Huaqiang Fang, Linda Groom, Aiwu Cheng, Wanrui Zhang, Jie Liu, Xianhua Wang, Kaitao Li, Peidong Han, Ming Zheng, Jinhu Yin, Weidong Wang, Mark P. Mattson, Joseph P. Y. Kao, Edward G. Lakatta, Shey-Shing Sheu, Kunfu Ouyang, Ju Chen, Robert T. Dirksen, Heping Cheng (2008) Superoxide Flashes in Single Mitochondria. Cell 134: 279-290.

5.    Chen-Leng Cai, Jody C. Martin, Yunfu Sun, Li Cui, Liangchun Wang, Kunfu Ouyang, Lei Yang, Lei Bu, Xingqun Liang, Xiaoxue Zhang, Williang B. Stallcup, Christopher P. Denton, Andrew McCulloch, Ju Chen & Sylvia M. Evans (2008) A myocardial lineage derives from Tbx18 epicardial cells. Nature 454: 104-108.

4.    Li-jun Yao, Gang Wang, Kun-fu Ou-Yang, Chao-liang Wei, Xian-hua Wang, Shi-rong Wang, Wei Yao, Hong-ping Huang, Jian-hong Luo, Cai-hong Wu, Jie Liu, Zhuan Zhou, He-ping Cheng (2006) Ca2+ sparks and Ca2+ glows in superior cervical ganglion neurons. Acta Pharmacol. Sin. 27: 848-852.

3.    Kunfu Ouyang*, Hui Zheng*, Xiaomei Qin, Chen Zhang, Dongmei Yang, Xian Wang, Caihong Wu, Zhuan Zhou & Heping Cheng (2005) Ca2+ sparks and secretion in dorsal root ganglion neurons. Proc. Natl. Acad. Sci. USA 102: 12259-12264 (*, Co-first Author).

2.    Kunfu Ouyang, Caihong Wu & Heping Cheng (2005) Ca2+-induced Ca2+ release in sensory neurons: low-gain amplification confers intrinsic stability. J. Biol. Chem. 280: 15898-15902.

1.    Ben-De Zou, Kun-Fu Ouyang, Yu-Zhen Chen, Cai-Hong Wu & Pei-Ai Zhou (2001) Blockade of U50488H on potassium currents of acutely isolated mouse hippocampal CA3 pyramidal neurons Brain Research 897: 52-59.


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