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赖卫华 教授、博士生导师    

赖卫华,二级教授,博士生导师,全国屠宰加工标准化技术委员会委员,江西省畜牧兽医学会副理事长,江西省营养学会常务理事。南昌大学首批“香樟杰才”,江西省双千计划首批培养类科技创新高端人才,江西省政府特殊津贴获得者,江西省主要学科学术及技术带头人,江西省新世纪百千万人才工程人选,江西省海外优秀人才。主持完成国家级课题6项,发表学术论文200余篇(H指数38),授权国家发明专利68项。《基于多种纳米材料速测关键技术的创新及应用》获得2020年度中国食品科学技术学会技术发明一等奖(排名第一);《纳米磁珠靶向高效分离技术的理论创新及应用》获得2020年度江西省自然科学一等奖(排名第四);《食品安全快速检测关键技术的研究与应用》获得2017年度江西省科技进步一等奖(排名第一);《可控粒径高吸光强度多枝状胶体金纳米粒子的制备方法》获得第四届江西省专利奖(2020年,排名第二);《食品中有毒有害物质快速检测新技术》获得2010年度中国轻工业联合会科学技术进步二等奖(排名第四);《瘦肉精胶体金免疫层析快速检测技术的研究》获得2006年度江西省技术发明二等奖(排名第二);获得2021年度江西省教学成果一等奖(排名第一)

致力于食品安全方面的研究并积极地将研究成果推广应用。在食品安全领域制定了第一个免疫层析方法检测“瘦肉精”的农业行业标准。所研发的食品安全快速检测产品覆盖全国31个省、自治区和直辖市,广泛应用于从农田到餐桌全过程的监管。研究成果为政府成功应对重大食品安全危机提供了技术支撑,为重大社会活动提供了食品安全保障,为农产品生产和食品工业可持续发展及广大人民群众舌尖上的安全提供了技术支持。

 

近期代表性论文

1 Huang Zhen, Hu Song, Xiong Yonghua, Wei Hua, Xu Hengyi, Duan Hongwei*, Lai Weihua*. Application and development of superparamagnetic nanoparticles in sample pretreatment and immunochromatographic assay. Trac-trends in Analytical Chemistry, 2019, 114: 151-170. 

2 Zhang Ganggang, Xu Shaolan, Xiong Yonghua, Duan Hong, Chen Wenyao, Li Xiangmin, Yuan Meifang, Lai Weihua*. Ultrabright fluorescent microsphere and its novel application for improving the sensitivity of immunochromatographic assay. Biosensors and Bioelectronics, 2019, 135: 173–180.

3 Xu Shaolan, Zhang Ganggang, Fang Bolong, Xiong Qirong, Duan Hongwei*, Lai Weihua*. Lateral flow immunoassay based on polydopamine-coated gold nanoparticles for the sensitive detection of zearalenone in maize. ACS Applied Material & Interfaces, 2019, 11(34): 31283-31290. 

4 Li Guoqiang, Huang Yanmei, Duan Miaolin, Xing Keyu, You Xingyong, Zhou Houde, Liu Yang, Liu Chengwei*, Liu Daofeng*, Lai Weihua*. Biosensing multiplexer based on immunochromatographic assay for rapid and high-throughput classification of Salmonella serogroups. Sensors and Actuators B: Chemical, 2019, 282: 317-321. 

5 Huang Zhen, Peng Juan, Han Jiaojiao, Zhang Ganggang, Huang Youju, Duan Miaolin, Liu Daofeng, Xiong Yonghua, Xia Shiqi, Lai Weihua*. A novel method based on fluorescent magnetic nanobeads for rapid detection of Escherichia coli O157:H7. Food Chemistry, 2019, 276: 333-341. 

6 Wang Chun, Xing Keyu, Zhang Ganggang, Yuan Meifang, Xu Shaolan, Liu Daofeng, Chen Wenyao, Peng Juan, Hu Song, Lai Weihua*. Novel ELISA based on fluorescent quenching of DNA-stabilized silver nanoclusters for detecting E. coli O157:H7. Food Chemistry, 2019, 281: 91-96. 

7 Fang Bolong, Hu Song, Wang Chun, Yuan Meifang, Huang Zhen, Xing Keyu, Liu Daofeng, Peng Juan*, Lai Weihua*. Lateral flow immunoassays combining enrichment and colorimetry-fluorescence quantitative detection of sulfamethazine in milk based on trifunctional magnetic nanobeads. Food Control, 2019, 98: 268-273.

8 Huang Zhen, Xiong Zhijuan, Chen Yuan, Hu Song, Lai Weihua*. Sensitive and matrix-tolerant lateral flow immunoassay based on fluorescent magnetic nanobeads for the detection of clenbuterol in swine urine. Journal of Agricultural and Food Chemistry, 2019, 67(10): 3028-3036. 

9 Lv Xi, Huang Yanmei, Liu Daofeng, Liu Chenwei, Shan Shan, Li Guoqiang, Duan Miaolin, Lai Weihua*. Multicolor and ultrasensitive enzyme-linked immunosorbent assay based on the fluorescence hybrid chain reaction for simultaneous detection of pathogens. Journal of Agricultural and Food Chemistry, 2019, 67(33): 9390-9398. 

10 Chen Wenyao, Huang Zheng, Hu Song, Peng Juan, Liu Daofeng, Xiong Yonghua, Xu Hengyi, Wei Hua, Lai Weihua*. Invited review: advancements in lateral flow immunoassays for screening hazardous substances in milk and milk powder. Journal of Dairy Science, 2019, 102(3): 1887-1990. 

11 Hu Song, Fang Bolong, Huang Zhen, Chen Yuan, Liu Daofeng, Xing Keyu, Peng Juan*, Lai Weihua*. Using molecular descriptors for assisted screening of heterologous competitive antigens to improve the sensitivity of ELISA for detection of enrofloxacin in raw milk. Journal of Dairy Science, 2019, 102(7): 6037-6046.

12 Ke-Yu Xing, Shan Shan, Dao-Feng Liu, Wei-Hua Lai*, Recent advances of lateral flow immunoassay for mycotoxins detection. Trends in Analytical Chemistry, 2020, 133, 116087. 

13 Hu Song, Huang Zhen, Wang Chun, Peng Juan*, Lai Weihua*. Using hapten cross-reactivity to screen heterologous competitive antigens for improving the sensitivity of ELISA. Food Chemistry, 2020, 303, 125379

14. Fang Bolong, Xu Shaolan, Huang Zhen, Wang Suhua, Chen Wenyao, Yuan Meifang, Hu Song, Peng Juan*, Lai Weihua*. Glucose oxidase-induced colorimetric immunoassay for qualitative detection of danofloxacin based on iron () chelation reaction with phenanthroline. Food Chemistry, 2020, 328, 127099

15. Fang Bolong, Xu Shaolan, Huang Youju, Su Fengmei, Huang Zheng, Fang Hao, Peng Juan, Xiong Yonghua, Lai Weihua*. Gold nanorods etching-based plasmonic immunoassay for qualitative and quantitative detection of aflatoxin M1 in milk. Food Chemistry, 2020, 329, 127160

16. Huang Zhen, Liu Yihui, Chen Yuan, Xiong Qirong, Wang Yuhui*, Duan Hongwei*, Lai Weihua*. Improving the performance of upconversion nanoprobe-based lateral flow immunoassays by supramolecular self-assembly core/shell strategies. Sensors and Actuators B: Chemical, 2020, 318, 128233

17. Chen Wenyao, Shan Shan, Peng Juan, Liu Daofeng, Xia Jun, Shao Bing*, Lai Weihua*. Sensitive and hook effect–free lateral flow assay integrated with cascade signal transduction system, Sensors and Actuators: B. Chemical. 2020, 321(1):128465. 

18. Xing Keyu, Peng Juan, Shan Shan, Liu Daofeng, Huang Yina, Lai Weihua*. Green enzyme-linked immunosorbent assay based on the single-stranded binding protein-assisted aptamer for the detection of mycotoxin. Analytical Chemistry. 2020, 92(12) : 8422-8426. 一区,IF 6.986

19. Hu Song, Liu Jintao, Zhang Ganggang, Wang Zexiang, Xiao Xiaoyue, Li Danhong, Peng Juan, Lai Weihua*. Reliable performance of aggregation-induced emission nanoparticle-based lateral flow assay for norfloxacin detection in nine types of animal-derived food. Talanta, 2020, 219,121245. 

20. Wang Suhua, Fang Bolong, Yuan Meifang, Wang Zexiang, Peng, Juan, Lai Weihua*. Dual-mode immunoassay system based on glucose oxidase-triggered Fenton reaction for qualitative and quantitative detection of danofloxacin in milk. Journal of Dairy Science, 2020, 103(9): 7826-7833

21 Xiaoyue Xiao, Song Hu, Xiaocui Lai, Juan Peng, Weihua Lai*. Developmental trend of immunoassays for monitoring hazards in food samples A review. Trends in food science & technology, 2021,111: 68-88. 

22 Xiaocui Lai, Ganggang Zhang, Lifeng Zeng, Xiaoyue Xiao, Juan Peng, Ping Guo, Wei Zhang, and Weihua Lai*. Synthesis of PDA-Mediated Magnetic Bimetallic Nanozyme and Its Application in Immunochromatographic Assay. Acs applied materials & interfaces, 2021,13,14131423. 

23 Miaolin Duan, Xiaoyue Xiao, Yanmei Huang, Guoqiang Li, Shan Shan, Xi Lv Houde Zhou, Silu Pen, Chengwei Liu, Daofeng Liu, Weihua Lai*. Immuno-HCR based on contact quenching and fluorescence resonance energy transfer for sensitive and low background detection of Escherichia coli O157: H7. Food chemistry, 3021, 334, 127568.

24 Gang-gang Zhang, Xiao-cui Lai, Neng-shui Ding, Qi-rong Xiong, Shuai Hou, Hong-wei Duan, Weihua Lai*. Chrysanthemum-like Au@Polydopamine synthesized using one-pot method and its advantage in immunochromatographic assay. Sensors & Actuators: B. Chemical, 2021, 343, 130097

25 ZexiangWangKeyu XingNengshui DingSuhua WangGanggang Zhang Weihua Lai*.Lateral flow immunoassay based on dual spectral-overlapped fluorescence quenching of polydopamine nanospheres for sensitive detection of sulfamethazine. Journal of Hazardous Materials, 2022, 423, 127204 

26 Hong Hu, Jun Xia, Nengshui Ding, Yonghua Xiong, Keyu Xing, Bolong Fang, Xi Huo, Weihua Lai*. A novel method based on Ag–Au nanorings with tunable plasmonic properties for the sensitive detection of amantadine. Journal of Hazardous Materials, 2022, 431, 128498 

30 Huanhuan Bao, Meifang Yuan, Chengui Xiao, Daofeng Liu, Weihua Lai*. Development of a signal-enhanced LFIA based on tyramine-induced AuNPs aggregation for sensitive detection of danofloxacin. Food Chemistry, 2022, 375, 131875

27 Xing Keyu, Peng Juan, Chen Wenyao, Fang Bolong, Liu, Daofeng, Shan Shan, Zhang Ganggang, Huang Yina, Lai Weihua*. Development of a label-free plasmonic gold nanoparticles aggregates sensor on the basis of charge neutralization for the detection of zearalenone. Food Chemistry, 2022, 370, 131365

28 Fang Bolong, Peng Juan, Zhang Gan, Xing Keyu, Chen Wenyao, Liu DaofengShan Shan, Xiong Yonghua, Lai Weihua*. I2/I- mediated fluorescence quenching of an Ag+-doped gold nanocluster-based immunoassay for sensitive detection of Escherichia coli O157: H7 in milk. Journal of Dairy Science, 2022, 105(4): 2922-2930

29 Xiaoyue Xiao, Yanmei Huang, Xuelong Zhao, Huanhuan Bao, Zhongwei Lu, Shan Shan, Daofeng Liu, Weihua Lai*. Intelligently identifiable membrane immunochip sensor based on Braille-like code for simultaneous multi-veterinary drug detection Sensors & Actuators: B. Chemical, 2022, In press,