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成果及论文

After joining SCUT

 

  1. Shengming Gan, Wenbo Wu, Guangxue Feng,* Zhiming Wang,* Bin Liu,* and Ben Zhong Tang,* Size optimization of organic nanoparticles with aggregation-induced emission characteristics for improved ROS generation and photodynamic cancer cell ablation. Small 2022. Accepted
           
       
     
  2. Shanshan Liu, Bingnan Wang, Yuewen Yu, Yubo Liu, Zeyan Zhuang, Zujin Zhao, Guangxue Feng,* Anjun Qin,* and Ben Zhong Tang,* Cationization-Enhanced Type I and Type II ROS Generation for Photodynamic Treatment of Drug-Resistant Bacteria. ACS Nano 2022. Accepted.
       
                                 
     
  3. Zhong-Hong, Zhu, Changjiang Bi, Hua-Hong Zou, Guangxue Feng,* Suping Xu,* and Ben Zhong Tang,* Smart Tetraphenylethene-Based Luminescent Metal–Organic Frameworks with Amide-Assisted Thermofluorochromics and Piezofluorochromics. Adv. Sci. 2022, 9(16), 2200850. 
           
       
     
  4. Xingchen Duan, Guo-Qiang Zhang, Shenglu Ji, Yiming Zhang, Jun Li, Hanlin Ou, Zhiyuan Gao, Guangxue Feng, and Dan Ding*, Activatable Persistent Luminescence from Porphyrin Derivatives and Supramolecular Probes with Imaging-Modality Transformable Characteristics for Improved Biological Applications. Angew. Chem. Int. Ed. 2022, 61, 24, e202116174.
              
  5. Jianqing Li, Zijuan Meng, Zeyan Zhuang, Bingnan Wang, Jun Dai, Guangxue Feng, Xiaoding Lou, Fan Xia, Zujin Zhao,* and Ben Zhong Tang, Effective Therapy of Drug-Resistant Bacterial Infection by Killing Planktonic Bacteria and Destructing Biofilms with Cationic Photosensitizer Based on Phosphindole Oxide. Small 2022, 18, 2200743.
              
     
  6. Zhong-Hong Zhu, Yubo Liu, Chi Song, Yating Hu,* Guangxue Feng,* and Ben Zhong Tang,  Porphyrin-Based Two-Dimensional Layered Metal–Organic Framework with Sono-/Photocatalytic Activity for Water Decontamination. ACS Nano 2022, 16, 1346-1357.                                                    .  


  7. Yuewen Yu, Shuang Wu, Le Zhang, Shidang Xu, Chunhui Dai, Shengming Gan, Ganfeng Xie,* Guangxue Feng,* and Ben Zhong Tang, Cationization to boost both type I and type II ROS generation for photodynamic therapy. Biomaterials. 2022, 280, 121255.
     
                                 
        
  8. Xin Zhou, Deping Wang, Zhiyuan Gao, Mingyue He, Jiayi Hou, Hui Zhang,* Guangqiang Zhang,* Dan Ding, Guangxue Feng,*  Highly sensitive light-up near-infrared fluorescent probe for detection and imaging of β-glucuronidase in human serum, living cells and tumor-bearing mice. Sci. China. Mater. 2022, 65, 836-844. https://doi.org/10.1007/s40843-021-1779-7      
                               
                                              
  9. Zhong-Hong Zhu, Zhiqiang Ni, Hua-Hong Zou, Guangxue Feng,* and Ben Zhong Tang,* Smart Metal Organic-Framework with Reversible Luminescence/Magnetic Switch Behavior for HCl Vapor Detection. Adv. Funct. Mater. 2021, 31, 2106925.
     
                                 
                                            
  10. Sheng Zeng, Heqi Gao, Chuang Li, Shaoqing Xing, Zhaoliang Xu, Qian Liu,* Guangxue Feng,* and Dan Ding,* Boosting Photothermal Theranostics via TICT and Molecular Motions for Photohyperthermia Therapy of Muscle-Invasive Bladder Cancer. Adv. Healthcare. Mater. 2021, 10, 2101063. (Back Cover)
       
                                     
                                              
  11. Shanshan Liu, Guangxue Feng,* Ben Zhong Tang,* and Bin Liu,* Recent Advances of AIE Light-Up Probes for Photodynamic Therapy. Chem. Sci. 2021, 12, 6488-6506.
     
                                 
                                            
  12. Guangxue Feng, Guo-Qiang Zhang, Dan Ding,* Design of superior phototheranostic agents guided by Jablonski diagram. Chem. Soc. Rev. 2020, 49, 8179-8234.
     
                 
                        

  13. Guangxue Feng, Can Wang, Chengjian Chen, Yutong Pan, Min Wu, Yuanbo Wang, Jie Liu, and Bin Liu,* Modulating Cell Specificity and Subcellular Localization by Molecular Charges and Lipophilicity. Chem. Mater. 2020, 32, 24, 10383-10393.



Before SCUT

  1. G. Feng, J. Liu, C.-J. Zhang, and B. Liu, Artemisinin and AIEgen Conjugate for Mitochondria-Targeted and Image-Guided Chemo- and Photodynamic Cancer Cell Ablation. ACS Appl. Mater. Interfaces 2018, 10, 11546.  

  2. G. Feng, and B. Liu, AIE Dots: The Emerging Theranostic Nanolights. Acc. Chem. Res. 2018， 51, 1404.  

  3.  G. Feng, D. Mao, J. Liu, C. C. Goh, L. G. Ng, D. Kong, B. T. Tang, and B. Liu, Polymeric Nanorods with Aggregation-Induced Emission Characteristics for Enhanced Cancer Targeting and Imaging. Nanoscale 2018, 10, 5869.  

  4. G. Feng, J. Li, C. Claser, A. Balachander, Y. Tan, C. C. Goh, I. K. W. Han, L. Rénia, B. Z. Tang, L. G. Ng, and B. Liu, Dual Modal Ultra-Bright Nanodots with Aggregation-Induced Emission and Gadolinium-Chelation for Vascular Integrity and Leakage Detection. Biomaterials 2018, 15, 77.  

  5. G. Feng, J. Liu, R. Liu, D. Mao, N. Tomczak, and B. Liu, Ultra-Small Conjugated Polymer Nanoparticles with High Specificity for Targeted Cancer Cell Imaging. Adv. Sci. 2017, 1600407.  

  6. G. Feng, Y. Fang, J. Liu, J. Geng, D. Ding and B. Liu,  Multifunctional Conjugated Polymer Nanoparticles for Image-Guided Photodynamic and Photothermal Therapy. Small 2017, 13, 1602807.  

  7. G. Feng, R. T. K, Kwok, B. Z. Tang, and B. Liu, Functionality and Versatility of Aggregation-Induced Emission Luminogens. Appl. Phys. Rev. 2017, 4, 021307.

  8. G. Feng, C.-J. Zhang, X. Lu, and B. Liu, Zinc(II)-Tetradentate-Coordinated Probe with Aggregation-Induced Emission Characteristics for Selective Imaging and Photoinactivation of Bacteria. ACS Omega 2017, 2, 546.

  9. G. Feng, W. Wu, S. Xu and B. Liu, Far red/near infrared AIE dots for image-guided photodynamic cancer cell ablation. ACS Appl. Mater. Interfaces 2016, 8, 21193.

  10. G. Feng and B. Liu, Multifunctional AIEgens for Future Theranostics. Small 2016, 12, 6528.

  11. G. Feng, W. Qin, Q. Hu, B. Z. Tang and B. Liu, Cellular and Mitochondria Dual Targeted Organic Dots with Aggregation-Induced Emission Characteristics for Image-Guided Photodynamic Therapy. Adv. Healthcare. Mater. 2015, 4, 2667.

  12. G. Feng, C.-K. Mai, R. Zhan, G. C. Bazan and B. Liu, Narrow Band Gap Conjugated Polyelectrolytes for Photothermal Killing of Bacteria. J. Mater. Chem. B. 2015, 3, 7340.

  13. G. Feng, Y. Yuan, F. Hu, R. Zhang, B. Xing, G. Zhang, D. Zhang and B. Liu, A Light-up probe with aggregation-induced emission characteristics (AIE) for selective imaging, naked-eye detection and photodynamic killing of Gram-positive bacteria. Chem. Commun. 2015, 51, 12490.

  14. G. Feng, J. Liu, J. Geng and B. Liu, Unfunctionalized conjugated polymer microparticles for selective cancer cell image-guided photothermal therapy. J. Mater. Chem. B. 2015, 3, 1135.

  15. G. Feng, C. Y. Tay, Q. Chui, R. Liu, N. Tomczak, J. Liu, B. Z. Tang, D. T. Leong and B. Liu, Ultrabright organic dots with aggregation-induced emission characteristic as a facile cell tracker. Biomaterials 2014, 35, 8669.

  16. G. Feng, J. Liu, R. Zhang and B. Liu, Cell imaging with red fluorescent light-up probe based on environment-sensitive fluorogen with intramolecular charge transfer characteristics. Chem. Commun. 2014, 50, 9497.

  17. G. Feng, K. Li, J. Liu, D. Ding and B. Liu, Bright Single-Chain Conjugated Polymer Dots Embedded Nanoparticles for Long-term Cell Tracing and Imaging. Small 2014, 6, 1212.

  18. G. Feng, D. Ding, K. Li, J. Liu and B. Liu, Reversible Photoswitching Conjugated Polymer Nanoparticles for Cell and Tumor Imaging. Nanoscale 2014, 4, 4141.

  19. G. Feng, J. Liang and B. Liu, Hyperbranched Conjugated Polyelectrolytes for Biological Sensing and Imaging. Macromol. Rapid Commun. 2013, 34, 705.

  20. G. Feng, D. Ding and B. Liu, Fluorescence Bioimaging with Conjugated Polyelectrolytes. Nanoscale 2012, 4, 6150.

  21. B. Wang,# G. Feng,# M. Seifrid, M. Wang, B. Liu, and G. C. Bazan, Antibacterial Narrow Band Gap Conjugated Oligoelectrolytes with High Photothermal Conversion Efficiency. Angew. Chem. Int. Ed. 2017, 56, 16063.(#共同一作)

  22. B. Guo,# G. Feng,# P. N. Manghnani, X. Cai, J. Liu, W. Wu, S. Xu, X. Cheng, C. The, B. Liu, A Porphyrin Based Co-Polymer for Highly Efficient In vitro and In vivo Potothermal Therapy. Small 2016, 12, 6243. (#共同一作)

  23. W. Wu,# G. Feng,# X. S and B. Liu, Red/Near Infrared Conjugated Polymer Photosensitizer with Aggregation-Induced Emission for Image-Guided Cancer Cell Ablation. Macromolecules 2016, 49, 5017. (#共同一作)

  24. B. Chen,# G. Feng,# B. He, C. Goh, S. Xu, G. Ramos-Ortiz, L. Aparicio-Ixta, J. Zhou, L. Ng, Z. Zhao, B. Liu and B. Z. Tang, Silole-Based Red Fluorescent Organic Dots for Bright Two-Photon Fluorescence In vitro Cell and In vivo Blood Vessel Imaging. Small 2016, 12, 782. (#共同一作)

  25. J. Liang,#  G. Feng,# R. T. K. Kwok, D. Ding, B. Z. Tang and B. Liu, AIEgen based light-up probes for live cell imaging. Sci. China Chem. 2016, 59, 53. (#共同一作)

  26. Y. Gao,# G. Feng,# C. Goh, L. Ng, B. Liu, B. Li, L. Yang and J. Hua, Biocompatible Nanoparticles Based on Diketo-pyrrolo-pyrrole (DPP) with Aggregation-Induced Red/NIR Emission for In Vivo Two-photon Fluorescence Imaging. Adv. Funct. Mater. 2015, 25, 2857. (#共同一作)

  27. Y. Yuan,# G. Feng,# W. Qin, B. Z. Tang and B. Liu, Targeted and Image-guided Photodynamic Cancer Therapy based on Organic Nanoparticles with Aggregation-induced Emission Characteristics. Chem. Commun. 2014, 50, 8587. (#共同一作)

  28. X. Gao, G. Feng, P. N. Manghnani, F. Hu, N. Jiang, J. Liu, B. Liu, J. Z. Sun and B. Z. Tang, A two-channel responsive fluorescent probe with AIE characteristics and its application for selective imaging of superoxide anions in living cells. Chem. Commun. 2017, 53, 1653.

  29. G. Jin, G. Feng, W. Qin, B. Z. Tang, B. Liu and K. Li, Multifunctional organic nanoparticles with aggregation-induced emission (AIE) characteristics for targeted photodynamic therapy and RNA interference therapy. Chem. Commun. 2016, 52, 2752.

  30. 30. C.-J. Zhang, G. Feng, S. Xu, Z. Zhu, X. Lu, J. Wu and B. Liu, Structure-Dependent cis/trans Isomerization of Tetraphenylethene Derivatives: Consequences for Aggregation-Induced Emission. Angew. Chem. Int. Ed. 2016, 55, 6192

  31. R. Zhang, G. Feng, C.-J. Zhang, X. Cai, X. Cheng and B. Liu, Real-Time Specific Light-Up Sensing of Transferrin Receptor: Image-Guided Photodynamic Ablation of Cancer Cells through Controlled Cytomembrane Disintegration. Anal. Chem. 2016, 88, 4841.

  32. M. Zhang, G. Feng, Z. Song, Y. Zhou, H. Chao, D. Yuan, T. T. Y. Tan, Z. Guo, Z. Hu, B. Z. Tang, B. Liu and D. Zhao, Two-dimensional metal-organic framework with wide channels and responsive turn-on fluorescence for the chemical sensing of volatile organic compounds. J. Am. Chem. Soc. 2014, 136, 7241.

  33. J. Liu, G. Feng, R. Liu, N. Tomczak, L. Ma, G. G. Gurzadyan and B. Liu, Bright Quantum-Dot-Sized Single-Chain Conjugated Polyelectrolyte Nanoparticles: Synthesis, Characterization and Application for Specific Extracellular Labeling and Imaging. Small 2014, 10, 3110.

  34. J. Liu, G. Feng, J. Geng and B. Liu, A Facile Strategy towards Conjugated Polyelectrolyte with Oligopeptide as Pendants for Biological Applications. ACS Appl. Mater. Interfaces 2013, 5, 4511.

  35. J. Liu, G. Feng, D. Ding and B. Liu, Bright far-red/near-infrared fluorescent conjugated polymer nanoparticles for targeted imaging of HER2-positive cancer cells. Polym. Chem. 2013, 4, 4326.

  36. Q. Hu, M. Gao, G. Feng and B. Liu, Mitochondria-Targeted Cancer Therapy Using a Light Up probe with Aggregation-induced Emission Characteristics. Angew. Chem. Int. Ed, 2014, 53, 14225.

  37. D. Ding, J. Liu, G. Feng, K. Li, Y. Hu and B. Liu, Bright Far-Red/Near-Infrared Conjugated Polymer Nanoparticles for In Vivo Bioimaging. Small 2013, 9, 3093.

  38. D. Ding, C. C. Goh, G. Feng, Z. Zhao, J. Liu, R. Liu, N. Tomczak, J. Geng, B. Z. Tang, L. G. Ng and B. Liu, Ultrabright Organic Dots with Aggregation-Induced Emission Characteristics for Real-Time Two-Photon Intravital Vasculature Imaging. Adv. Mater. 2013, 25, 6083.

  39. W. Qin, K. Li, G. Feng, M. Li, Z. Yang, B. Liu and B. Z. Tang, Bright and photostable Organic Fluorescent Dots with Aggregation-Induced Emission Characteristics for Noninvasive Long-term Cell Imaging. Adv. Funct. Mater. 2013. 24, 635.

  40. Y. Yuan, R. T. K. Kwok, G. Feng, J. Liang, J. Geng, B. Z. Tang and B. Liu, Rational Design of Fluorescent Light-Up Probes Based on an AIE Luminogen for Targeted Intracellular Thiol Imaging. Chem. Commun. 2014, 50, 295.

  41. M. Gao, Q. Hu, G. Feng, B. Z. Tang and B. Liu, Fluorescent light-up probe with “AIE + ESIPT” characteristics for specific detection of lysosomal esterase. J. Mater. Chem. B. 2014, 2, 3438.

  42. X. Cai, R. Zhan, G. Feng and B. Liu, Organometallic Conjugated Polyelectrolytes: Synthesis and Applications. J. Inorg. Org. Polym. Mater. 2014, 25, 27.

  43. C. Zhang, Q. Hu, G. Feng, R. Zhang, Y. Yuan, X. Lu and B. Liu, Image-guided combination chemotherapy and photodynamic therapy using a mitochondria-targeted molecular probe with aggregation-induced emission characteristics. Chem. Sci. 2015, 6, 4580.

  44. M. Gao, Q. Hu, G. Feng, N. Tomczak, R. Liu, B. Xing, B. Z. Tang and B. Liu, A Multifunctional Probe with Aggregation-Induced Emission Characteristics for Selective Fluorescence Imaging and Photodynamic Killing of Bacteria Over Mammalian Cells. Adv. Healthcare Mater. 2015, 4,659.

  45. C. F. A. Gomez-Duran, R. Hu, G. Feng, T. Li, F Bu, M. Arseneault, B. Liu, E. Peña-Cabrera and B. Z. Tang, Effect of AIE Substituents on the Fluorescence of Tetraphenylethene-Containing BODIPY Derivatives. ACS Appl. Mater. Interfaces 2015, 7, 15168.

  46. Q. Hu, M. Gao, G. Feng, X. Chen and B. Liu, A Cell Apoptosis Probe Based on Fluorogen with Aggregation Induced Emission Characteristics. ACS Appl. Mater. Interfaces 2015, 7, 4875.

  47. J. Xiang, X. Cai, X. Lou, G. Feng, X. Min, W. Luo, B. He, C. C. Goh, L. G. Ng, J. Zhou, Z. Zhao, B. Liu and B. Z. Tang, Biocompatible Green and Red Fluorescent Organic Dots with Remarkably Large Two-Photon Cross Action Sections for Targeted Cellular Imaging and Real-Time Intravital Blood Vascular Visualization. ACS Appl. Mater. Interfaces 2015, 7, 14965.

  48. D. Ding, R. T. K. Kwok, Y. Yuan, G. Feng, B. Z. Tang and B. Liu, Fluorescent Light-up Nanoparticle Probe with Aggregation-induced Emission Characteristics and Tumor-acidity Responsiveness for Targeted Imaging and Selective Suppression of Cells. Mater. Horizon. 2015, 2, 100.

  49. D. Ding, J. Liang, H. Shi, R. T. K. Kwok, M. Gao, G. Feng, Y. Yuan, B. Z. Tang and B. Liu, Light-Up Bioprobe with Aggregation-Induced Emission Characteristics for Real-Time Apoptosis Imaging in Target Cancer Cells. J. Mater. Chem. B 2013, 2, 231.

  50. M. Gao, C. K. Sim, C. W. T. Leung, Q. Hu, G. Feng, F. Xu, B. Z. Tang and B. Liu, A fluorescent light-up probe with AIE characteristics for specific mitochondrial imaging to identify differentiating brown adipose cells. Chem. Commun. 2014, 50, 8312.

  51. R. Zhang, Y. Yuan, J. Liang, R. T. K. Kwok, Q. Zhu, G. Feng, J. Geng, B. Z. Tang and B. Liu, Fluorogen-peptide conjugates with tunable aggregation-induced emission characteristics for bioprobe design. ACS Appl. Mater. Interfaces 2014, 6, 14302.

  52. Y. Hu, C. Guan, G. Feng, Q. Ke, X. Huang and J. Wang, Flexible Asymmetric Supercapacitor Based on Structure-Optimized Mn3O4/Reduced Graphene Oxide Nanohybrid Paper with High Energy and Power Density. Adv. Funct. Mater. 2015, 25, 7291.

  53. L. Peng, M. Gao, X. Cai, R. Zhang, K. Li, G. Feng, A. Tong and B. Liu, A fluorescent light-up probe based on AIE and ESIPT processes for β-galactosidase activity detection and visualization in living cells. J. Mater. Chem. B. 2015, 3, 9168.

  54. Ruoyu Zhang, Chong-Jing Zhang, G. Feng, Fang Hu, Jigang Wang, Bin Liu, Specific Light-Up Probe with Aggregation-Induced Emission for Facile Detection of Chymase. Anal. Chem. 2016, 88, 9111.

  55. R. Zhang, X. Cai, G. Feng and B. Liu, Real-time Naked-eye Multiplex Detection of Toxin and Bacteria using AIEgens with the Assistance of Graphene Oxide. Faraday Discuss. 2019, 196, 363.

  56. C.-J. Zhang, J. Wang, J. Zhang, Y. M. Lee, G. Feng, Teck Kwang Lim, Han-Ming Shen, Qingsong Lin, Bin Liu, Mechanism-Guided Design and Synthesis of a Mitochondria-Targeting Artemisinin Analogue with Enhanced Anticancer Activity. Angew. Chem. Int. Ed. 2016, 128, 13974.

  57. B. Guo, X. Cai, S. Xu, S. M. A. Fateminia, J. Liu, J. Liang, G. Feng, W. Wu and B. Liu, Decoration of porphyrin with tetraphenylethene: converting a fluorophore with aggregation-caused quenching to aggregation-induced emission enhancement. J. Mater. Chem. B, 2016, 4, 4690.

  58. R. Zhang, S. H. P. Sung, G. Feng, C.-J. Zhang, K. Kenry, B. Z. Tang, and B. Liu, AIE probe for specific turn-on quantification of sTfR: an important disease marker for iron deficiency anemia and kidney diseases. Anal. Chem. 2018, 90, 1154.

  59. B. Gu, W. Wu, G. Xu, G. Feng, F. Yin, P. H. J. Chong, J. Qu, K.-T. Yong and B. Liu, Precise Two-Photon Photodynamic Therapy using an Efficient Photosensitizer with Aggregation-Induced Emission Characteristics. Adv. Mater. 2017, 29, 1701076.

  60. S. Xu, W. Wu, X. Cai, C.-J. Zhang, Y. Yuan, J. Liang, G. Feng, P. N. Manghnani and B. Liu, Highly efficient photosensitizers with aggregation-induced emission characteristics obtained through precise molecular design. Chem. Commun. 2017, 53, 8727. 

  61. J. Liu, M. Evrard, X. Cai, G. Feng, N. Tomczak, L. Ng and B. Liu, Organic nanoparticles with ultrahigh quantum yield and aggregation-induced emission characteristics for cellular imaging and real-time two-photon lung vasculature imaging. J. Mater. Chem. B. 2018, 6, 2630.

  62. F. Hu, P. N. Manghnani, K. Kenry, G. Feng, W. Wu, C. The, and B. Liu, Visualize Embryogenesis and Cell Fate Using Fluorescent Probes with Aggregation-Induced Emission. ACS Appl. Mater. Interfaces 2019, 11, 3737.

  63. X. Cai. F. Hu, G. Feng, R.T.K. Kwok, B. Liu and B. Z. Tang, Organic Mitoprobes based on Fluorogens with Aggregation-induced Emission. Israel J. Chem. 2018, 58, 860.