一、学术论文
1. Qin Li#, Yanhong Zheng#, Lijun Guo, Ying Xiao, Haiyue Li, Pingping Yang, Li Xia, Xiangqing Liu, Zhangyan Chen, Li Li, Huaidong Zhang*, Microbial degradation of tecracycline antibiotics: Mechanisms and environmental implications.
Journal of Agricultural and Food Chemistry, 2024
2. Junyu Chen, Lijun Guo, Chenglong Wang, Peng Peng, Jiaming Wu, Huaidong Zhang, Feng Liu*, Qin Li*, Can irisin be developed as the molecular evolutionary clock based on the origin and functions? General And Comparative Endocrinology, 2024, 352: 114515.
3. Cui Yu, Lin Chen, Yangle Gao, Jia Liu, Peilin Li, Mingliang Zhang, Qin Li, Huaidong Zhang*, Mancheng Tang*, Li Li*, Discovery and biosynthesis of macrophasetins from the plant pathogen fungus Macrophomina phaseolina. Frontiers in Microbiology, 2022, 13: 1056392.
4. Mingliang Zhang, Yangle Gao, Cui Yu, Jun Wang, Kexin Weng, Qin Li, Yongjin He, Zheng Guo, Huaidong Zhang*, Jianzhong Huang, Li Li*, Transcriptome analysis of malate-induced Schizochytrium sp. FJU-512 reveals a novel pathway for biosynthesis of docosahexaenoic acid with enhanced expression of genes responsible for acetyl-CoA and NADPH accumulation. Frontiers in Microbiology, 2022, 13: 1006138.
5. Boyan Lv#, Youhui Zeng#, Huaidong Zhang#, Zhongyan Li, Zhaorong Xu, Yan Wang, Yuanyuan Gao, Yajuan Chen, and Xinmiao Fu*, Mechanosensitive channels mediate hypoionic shock-induced aminoglycoside potentiation against bacterial persisters by enhancing antibiotic uptake. Antimicrobial Agents and Chemotherapy, 2022, 66(2): e0112521.
6. Shimin Li, Dianbing Wang, Abbas Ghulam, Xia Li, Min Li, Qin Li, Yingxin Ma, Lei Wang, Hangshen Wu, Zongqiang Cui, and Xian-En Zhang*, Tracking the replication-competent zika virus with tetracysteine-tagged capsid protein in living cells. Journal of Virology, 2022, 96(7): e0184621.
7. Yangle Gao#, Mengsi Xie#, Cui Yu, Mingliang Zhang, Jianzhong Huang, Qin Li, Huaidong Zhang, and Li Li*, Heterologous expression of macrollins from phytopathogenic Macrophomina phaseolina revealed a cytochrome P450 mono-oxygenase in the biosynthesis of β-hydroxyl tetramic acid. Journal of Agricultural and Food Chemistry, 2021, 69(50): 15175-15183.
8. Wei Li#, Ji Liu#, Yuanyuan Liu, Qin Li, Wen Yin, Kevin K Wanderi, Xiaowei Zhang, Zhiping Zhang, Xian-En Zhang, Zongqiang Cui*, HIV-1 uses dynamic podosomes for entry into macrophages. Journal of Virology, 2021, 95(10): e02480-20.
9. Mingliang Zhang#, Huaidong Zhang#*, Qin Li, Yangle Gao, Lijun Guo, Liu He, Shanshan Zang, Xing Guo, Jianzhong Huang*, Li Li*, Structural insights into the trans-Acting enoyl reductase in the biosynthesis of long-chain polyunsaturated fatty acids in Shewanella piezotolerans. Journal of Agricultural and Food Chemistry, 2021, 69(7): 2316-2324.
10. Xia Li, Dianbing Wang, Zongqiang Cui, Qin Li, Min Li, Yingxin Ma, Qinxue Hu, Yikai Zhou, Xian-En Zhang*, HIV-1 viral cores enter the nucleus collectively through the nuclear endocytosis-like pathway. Science China-Life Sciences, 2021, 64(1): 66-76.
11. Yingli Zhang, Siyu Gong, Xuan Wang, Murtala Muhammad, Yangyang Li, Shuaishuai Meng, Qin Li, Dong Liu*, Huaidong Zhang*, Insights into the inhibition of Aeromonas hydrophila D-alanine-D-alanine ligase by integration of kinetics and structural analysis. Journal of Agricultural and Food Chemistry, 2020, 68(28): 7509-7519.
12. Xue Wang, Yangle Gao, Mingliang Zhang, Huaidong Zhang, Jianzhong Huang, Li Li*. Genome mining and biosynthesis of the Acyl-CoA: cholesterol acyltransferase inhibitor beauveriolide I and III in Cordyceps Militaris. Journal of Biotechnology, 2020, 309: 85-91.
13. Wen Yin#, Wei Li#, Qin Li, Yuanyuan Liu, Ji Liu, Min Ren, Yingxin Ma, Zhiping Zhang, Xiaowei Zhang, Yuntao Wu, Shibo Jiang, Xian-En Zhang*, Zongqiang Cui*. Real-time Imaging of Individual Virion-triggered Cortical Actin Dynamics for Human Immunodeficiency Virus Entry into Resting CD4 T Cells. Nanoscale, 2020, 12(1): 115-129.
14. Huaidong Zhang*, Jie Chen, Houjin Zhang*. Molecular characterization of the hydroxylase HmtN at 1.3 Å resolution. Biochemical and Biophysical Research Communications, 2019, 516(3): 1033-1038.
15. Yangle Gao, Mingliang Zhang, Xue Wang, Huaidong Zhang, Jianzhong Huang, Li Li*. Isolation and characterization of a new cytotoxic polyketide-amino acid hybrid from Thermothelomyces thermophilus ATCC 42464. Natural Product Research, 2019, 16: 1-7.
16. Hang Yang, Yujing Gong, Huaidong Zhang, Irina Etobayeva, Paulina Miernikiewicz, Dehua Luo, Xiaohong Li, Xiaoxu Zhang, Krystyna Dabrowska, Daniel C Nelson*, Jin He*, Hongping Wei*. ClyJ is a novel Pneumococcal chimeric lysin with a cysteine- and histidine-dependent amidohydrolase/peptidase catalytic domain. Antimicrobial Agents and Chemotherapy. 2019, 63(4): e02043-18.
17. Chong Qin, Wei Li, Qin Li, Zhiping Zhang, Xiaowei Zhang, Xian-En Zhang, Zongqiang Cui*. Real-time Dissection of Dynamic Uncoating of Individual Influenza Viruses. Proceedings of the National Academy of Sciences of the United States of America, 2019, 116(7): 2577-2582.
18. Xianyu Zhu, Yong Zhao, Huaidong Zhang, Wenxia Wang, Haihua Cong, Heng Yin*. Characterization of the specific mode of action of a chitin deacetylase and separation of the partially acetylated chitosan oligosaccharides. Marine Drugs. 2019, 17(2): E74.
19. Qin Li, Wen Yin, Wei Li, Zhiping Zhang, Xiaowei Zhang, Xian-En Zhang, Zongqiang Cui*. Encapsulating Quantum Dots within HIV-1 Virions through Site-Specific Decoration of the Matrix Protein Enables Single Virus Tracking in Live Primary Macrophages. Nano Letters, 2018, 18(12): 7457-7468.
20. Huaidong Zhang, Qin Li*, Lina Wang, Yan Chen. Investigation of structure and function of mitochondrial alcohol dehydrogenase isozyme III from Komagataella phaffii GS115. Biochimica et Biophysica Acta – General Subjects, 2018, 1862(5): 1199-1208.
21. Huaidong Zhang, Ximing Xu*. Protein acetylation: an important mechanism in actinobacteria. Bioscience Reports, 2018, 38(2): BSR20170851
22. Wen Yin, Wei Li, Qin Li, Chong Qin, Zhiping Zhang, Xiaowei Zhang, Xian-En Zhang*, Zongqiang Cui*. Structural Characterization and Analysis of Human Immunodeficiency Virus Encapsulating Quantum Dots. Journal of Nanoscience and Nanotechnology, 2018, 18(7): 4487-4494.
23. Qin Li#, Wei Li#, Wen Yin, Jia Guo, Zhiping Zhang, Dejun Zeng, Xiaowei Zhang, Yuntao Wu, Xian-En Zhang*, Zongqiang Cui*. Single-Particle Tracking of Human Immunodeficiency Virus Type 1 Productive Entry into Human Primary Macrophages. ACS Nano, 2017, 11(4): 3890-3903.
24. Qin Li, Yan Chen, Guiqin Zhang, Huaidong Zhang*. Structural analysis of SgvP involved in carbon-sulfur bond formation during griseoviridin biosynthesis. FEBS Letters, 2017, 591(9): 1295-1304.
25. Yaping Sun, Huaidong Zhang, Jian Shi, Zhe Zhang, Rui Gong*. Identification of a novel inhibitor against Middle East respiratory syndrome coronavirus. Viruses-Basel, 2017, 9(9): E255.
26. Hang Yang, Huaidong Zhang, Jing Wang, Junping Yu, Hongping Wei*. A novel chimeric lysin with robust antibacterial activity against planktonic and biofilm methicillin-resistant Staphylococcus aureus. Scientific Reports. 2017, 7: 40182.
27. Huaidong Zhang#, Guimin Zhang#, Chaoxiang Yao, Muhammad Junaid, Zhenghui Lu, Houjin Zhang*, Yanhe Ma*. Structural insight of a trimodular halophilic cellulase with a family 46 carbohydrate-binding module. PLoS ONE, 2015, 10(11): e0142107.
28. Jian Shi, Huaidong Zhang, Rui Gong*, Gengfu Xiao*. Characterization of the fusion core in Zebrafish endogenous retroviral envelope protein. Biochemical and Biophysical Research Communications, 2015, 460: 633-638.
29. Hua Wang, Huaidong Zhang, Yi Zou, Yanling Mi, Shuangjun Lin, Zhixiong Xie, Yunjun Yan, Houjin Zhang*. Structural insight into the tetramerization of an iterative ketoreductase SiaM through aromatic residues in the interfaces. PLoS ONE, 2014, 9(6): e97996.
30. Daiming Zha, Huaidong Zhang, Houjin Zhang, Li Xu, Yunjun Yan*. N-terminal transmembrane domain of lipase LipA from Pseudomonas protegens Pf-5: A must for its efficient folding into an active conformation. Biochimie, 2014, 105: 165-171.
31. Hua Wang, Huaidong Zhang, Yanling Mi, Jianhua Ju, Qi Chen, Houjin Zhang*. Expression, crystallization and preliminary X-ray analysis of McbB, a multifunctional enzyme involved in β-carboline skeleton biosynthesis. Acta Crystallographica Section F, 2014, F70: 1402-1405.
32. Huaidong Zhang, Jie Chen, Hua Wang, Yunchang Xie, Jianhua Ju, Yunjun Yan*, Houjin Zhang*. Structural analysis of HmtT and HmtN involved in the tailoring steps of himastatin biosynthesis. FEBS Letters, 2013, 587(11): 1675-1680.
33. Lina Zheng, Xiang Zhou, Huaidong Zhang, Xiaofeng Ji, Lei Li, Lin Huang, Linquan Bai*, Houjin Zhang*. Structural and functional analysis of validoxylamine A 7'-phosphate synthase ValL involved in validamycin A biosynthesis. PLoS ONE, 2012, 7(2): e32033.
二、发明专利
张怀东，李芹，黄建忠，何柳，郭丽君，郭兴，罗鑫格，一种细胞穿膜肽-目的蛋白复合物的制备及其高效导入链霉菌活细胞的方法，授权号：ZL202210405075.2
李力，高扬乐，张明亮，张怀东，于翠，聚酮化合物及其制备方法和用途，授权号：ZL201910994053.2
崔宗强，印文，李炜，张先恩，李芹，刘霁，一种抑制肌动蛋白重组的多肽及应用，授权号：ZL201810159838.3
龚睿，张怀东，一种靶向埃博拉病毒囊膜蛋白的高亲和力单域抗体及其制备方法与应用，授权号：ZL201810183021.X
龚睿，张怀东，一种中和新疆出血热病毒的单域抗体，授权号：ZL201610574526.X