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成果及论文

(共同)通讯作者论文:

(21) Wang, Jia-Wang*; Zhu, Qing-Wei; Liu, Deguang; Chen, Pei-Wen; Chen, Hong-Zhong; Lu, Xi*; Fu, Yao*

Nickel-Catalyzed α-selective Hydroalkylation of Vinylarenes.

Angew. Chem. Int. Ed. 2024, 63, e202413074.


(20) Li, Yan; Liu, Deguang; Hu, Xiao; Zhang, Jun-Yang; Zhu, Qing-Wei; Men, Boru; Gao, Gen-Wei; Chen, Pei-Wen; Tong, Yi-Zhou; Chang, Zhe; Li, Zhen; Lu, Xi*; Fu, Yao*

Enantioselective alkene hydroalkylation overcoming heteroatom constraints via cobalt catalysis.

Nat. Synth. 2024, 3, 1134.


(19) Liu, Deguang; Wang, Jia-Wang; Lu, Xi*; Fu, Yao*

Entropy Effects in Temperature-Regulated Nickel-Catalyzed Regiodivergent Alkene Hydroalkylation.

Org. Chem. Front. 2024, 11, 3648.

Invited by Prof. Shengming Ma: Emerging Investigator Series – Organic Chemistry Frontiers


(18) Chang, Zhe; Yao, Cheng-Yu; Feng, Wen-Jie; Zhao, Yi-Fan; Qian, Ru-Ru; Hu, Xiao; Li, Yan; Liu, Deguang; Lu, Xi*; Fu, Yao*

Generation of Hydrides or Hydrogen Radicals for Hydrodehalogenation and Deuterodehalogenation of gem-Dihaloalkenes.

CCS Chem. In press, DOI: 10.31635/ccschem.024.202403958.


(17) Shi, Hongjin; Yin, Guoyin*; Lu, Xi*; Li, Yangyang*

Stereoselective synthesis of 2-deoxy-α-C-glycosides from glycals.

Chin. Chem. Lett. 2024, 35109674.


(16) Li, Zhen; Liu, Bingxue; Yao, Cheng-Yu; Gao, G.-W.; Zhang, Jun-Yang; Tong, Yi-Zhou; Zhou, Jing-Xiang; Sun, Hao-Kai; Liu, Qiang*; Lu, Xi*; Fu, Yao*

Ligand-Controlled Cobalt-Catalyzed Regio‑, Enantio‑, and Diastereoselective Oxyheterocyclic Alkene Hydroalkylation.

J. Am. Chem. Soc. 2024, 146, 3405.

Highlighted by 《有机化学》


(15) Li, Yan; Lu, Xi*; Fu, Yao*

Recent Advances in Cobalt-Catalyzed Regio- or Stereoselective Hydrofunctionalization of Alkenes and Alkynes.

CCS Chem. 2024, 6, 1130.



(14) Wan, Lei; Tong, Yizhou; Lu, Xi*; Fu, Yao*

Cobalt-catalyzed reductive alkynylation to construct C(sp)-C(sp3) and C(sp)-C(sp2) bonds.

Chin. Chem. Lett. 2024, 35, 109283.


(13) Zhang, Zhi-Lin; Li, Zhen; Xu, Yu-Tai; Yu, Lu; Kuang, Jian; Li, Yan; Wang, Jia-Wang; Tian, Changlin; Lu, Xi*; Fu, Yao*

Cobalt-Catalyzed Facial-Selective Hydroalkylation of Cyclopropenes.

Angew. Chem. Int. Ed. 2023, 62, e202306381.


(12) Wang, Jia-Wang; Li, Zhen; Liu, Deguang; Zhang, Jun-Yang; Lu, Xi*; Fu, Yao*

Nickel-Catalyzed Remote Asymmetric Hydroalkylation of Alkenyl Ethers to Access Ethers of Chiral Dialkyl Carbinols.

J. Am. Chem. Soc. 2023, 145, 10411.

Highlighted by Organic Chemistry Portal


(11) Liu, Bingxue; Liu, Deguang; Rong, Xianle; Lu, Xi*; Fu, Yao*; Liu, Qiang*

Ligand-Controlled Stereoselective Synthesis of 2-Deoxy-β-C-glycosides by Cobalt Catalysis.

Angew. Chem. Int. Ed. 2023, 62, e202218544.

Highlighted by Organic Chemistry Portal

Highlighted by Synfacts


(10) Li, Yan; Liu, Deguang; Wan, Lei; Zhang, Jun-Yang; Lu, Xi*; Fu, Yao*

Ligand-Controlled Cobalt-Catalyzed Regiodivergent Alkyne Hydroalkylation.

J. Am. Chem. Soc. 2022, 144, 13961.

Highlighted by Organic Chemistry Portal

Highlighted by Organic Chemistry Portal (Synthesis of substituted alkenes)

Highlighted by Synfacts


(9) Wang, Jia-Wang; Liu, De-Guang; Chang, Zhe; Li, Zhen; Fu, Yao; Lu, Xi*

Nickel-Catalyzed Switchable Site-Selective Alkene Hydroalkylation by Temperature Regulation.

Angew. Chem. Int. Ed. 2022, 61, e202205537.


(8) Wang, Xiao-Xu; Xu, Yuan-Tai; Zhang, Zhi-Lin; Lu, Xi*; Fu, Yao*

NiH-catalysed proximal-selective hydroalkylation of unactivated alkenes and the ligand effects on regioselectivity.

Nat. Commun. 2022, 13, 1890.

Highlighted by Synfacts


(7) Li, Yan; Nie, Wan; Chang, Zhe; Wang, Jia-Wang; Lu, Xi*; Fu, Yao*

Cobalt-catalysed enantioselective C(sp3)–C(sp3) coupling.

Nat. Catal. 2021, 4, 901.

Highlighted by NSFC

Highlighted by Synfacts


(6) Wang, Xiao-Xu; Yu, Lu; Lu, Xi*; Zhang, Zhi-Lin; Liu, De-Guang; Tian, Changlin; Fu, Yao*

NiH-Catalyzed Reductive Hydrocarbonation of Enol Esters and Ethers.

CCS Chem. 2022, 4, 605.


(5) Wang, Jia-Wang; Li, Yan; Nie, Wan; Chang, Zhe; Yu, Zi-An; Zhao, Yi-Fan; Lu, Xi*; Fu, Yao*

Catalytic asymmetric reductive hydroalkylation of enamides and enecarbamates to chiral aliphatic amines.

Nat. Commun. 2021, 12, 1313.

Nature Communications Editors' Highlights


(4) Wang, Xiao-Xu; Lu, Xi*; Li, Yan; Wang, Jia-Wang; Fu, Yao*

Recent advances in nickel-catalyzed reductive hydroalkylation and hydroarylation of electronically unbiased alkenes.

Sci. China Chem. 2020, 63, 1586.


(3) Wang, Xiao-Xu; Lu, Xi*; He, Shi-Jiang; Fu, Yao*

Nickel-catalyzed three-component olefin reductive dicarbofunctionalization to access alkylborates.

Chem. Sci. 2020, 11, 7950.


(2) He, Shi-Jiang; Wang, Jia-Wang; Li, Yan; Xu, Zhe-Yuan; Wang, Xiao-XuLu, Xi*; Fu, Yao*

Nickel-Catalyzed Enantioconvergent Reductive Hydroalkylation of Olefins with α-Heteroatom Phosphorus or Sulfur Alkyl Electrophiles.

J. Am. Chem. Soc. 2020, 142, 214.

Highlighted by Synfacts


(1) Lu, Xi*; Wang, Xiao-Xu; Gong, Tian-Jun; Pi, Jing-Jing; He, Shi-Jiang; Fu, Yao*

Nickel-catalyzed allylic defluorinative alkylation of trifluoromethyl alkenes with reductive decarboxylation of redox-active esters.

Chem. Sci. 2019, 10, 809.

Highlighted by Synfacts