Huimin Chang, Simon Clemens, Pingting Gao, Quanlin Li, Hanqing Zhao, Lehua Wang, Jingye Zhang, Pinghong Zhou*, Kai Johnsson*, and Lu Wang*. Fluorogenic Rhodamine-Based Chemigenetic Biosensor for Monitoring Cellular NADPH Dynamics, J. Am. Chem. Soc. 2024, https://doi.org/10.1021/jacs.3c13137. 

Dongjuan Si, Quanlin Li, Yifan Bao, Jingye Zhang,*  Lu Wang*,  Fluorogenic and Cell-Permeable Rhodamine Dyes for High-Contrast Live-Cell Protein Labeling in Bioimaging and Biosensing,  Angew. Chem. Int. Ed. 2023, e202307641.

(https://onlinelibrary.wiley.com/doi/10.1002/anie.202307641)

Gangwei Jiang, Tian-Bing Ren, Elisa D’Este, Mengyi Xiong, Bin Xiong, Kai Johnsson, Xiao-Bing Zhang, Lu Wang*, Lin Yuan*.A synergistic strategy to develop photostable and bright dyes with long Stokes shift for nanoscopy, Nat. Comm. 2022,13, 2264. (https://assets.researchsquare.com/files/rs-885436/v1/b47895c2-2d2f-4424-8bfa-68ace6cad016.pdf?c=1632410647)

Nicolas Lardon, Lu Wang*, Aline Tschanz, Philipp Hoess, Mai Tran, Elisa D’Este, Jonas Ries, and Kai Johnsson*, .J. Am. Chem. Soc. 2021, 143, 36, 14592–14600

 Lu Wang,* Mai Tran, Elisa D’Este, Julia Roberti, Birgit Koch, Lin Xue, Kai Johnsson*, A general strategy to develop cell permeable and fluorogenic probes for multi-colour nanoscopy. Nat.Chem. 2020, 12, 165–172. (Highly Cited Paper). Probe commercialized by Spirochrome (SPY probes) https://spirochrome.com/products/spy-probes/

  Lu Wang*^,1, Julien Hiblot¹, Christoph Popp, Lin Xue, Kai Johnsson*, Environmentally Sensitive Color-Shifting Fluorophores for Bioimaging. Angew. Chem. Int. Ed. 2020, 2020, 59, 21880 (VIP paper) (¹Equally contributing authors)

 Wei Li¹, Lu Wang¹, Shulu Yin, Huanhua Lai, Lin Yuan,* Xiaobing Zhang, Engineering a Highly Selective Probe for Ratiometric Imaging H2Sn and Revealing its Signaling Pathway in Fatty Liver Disease, Chem. Sci., 2020, 11, 7991-7999.  (¹Equally contributing authors)

 Lu Wang, Michelle S. Frei, Aleksandar Salim, Kai Johnsson, Small-Molecule Fluorescent Probes for Live-Cell Super-Resolution Microscopy. J. Am. Chem. Soc. 2019,141, 7, 2770. (Highly Cited Paper)

 Lu Wang,¹ Dongdong Su,¹ Stuart Berry, Jung Yeol Lee, Young-Tae Chang, A New Approach for Turn-on Fluorescence Sensing of L-DOPA. Chem. Comm. 2017, 53, 12465-12468.  (¹Equally contributing authors)

 Lu Wang, Jingye Zhang, Beomsue Kim, et al, Boronic Acid: A Bio-Inspired Strategy to Increase the Sensitivity and Selectivity of Fluorescent NADH Probe. J. Am. Chem. Soc. 2016, 138, 10394.

Lu Wang, Lin Yuan, Xian Zeng, et al, Multisite-binding switchable fluorescent probe for monitoring mitochondrial ATP level fluctuation in live cells, Angew. Chem. Int. Ed. 2016, 55, 1773–1776. Probe commercialized by Merck, MedChemExpress, et. al https://www.merckmillipore.com/INTL/en/product/BioTracker-ATP-Red-Live-Cell-Dye,MM_NF-SCT045

Lin Yuan¹, Lu Wang¹, Bikram Keshari Agrawalla, et al, Development of targetable two-photon fluorescent probes to image hypochlorous acid in mitochondria and lysosome in live cell and inflamed mouse model. J. Am. Chem. Soc., 2015, 137, 5930–5938. (¹Equally contributing authors) (Highly Cited Paper)

 Lu Wang¹, Zhichao Fan¹, Jingye Zhang, et al. Evaluating tumor metastatic potential by imaging intratumoral acidosis via ph-activatable near-infrared fluorescent probe. Int. J. Cancer, 2015, 136, E107-E116. (¹Equally contributing authors)

 Lu Wang, Xiao Zhu, Cheng Xie, et al, Imaging intratumoral acidosis by using a pH-activatable near-infrared fluorescence probe. Chem. Comm. 2012, 48, 11677-11679.

 Lu Wang, Jiefu Jin, et al. A cyanine based fluorophore emitting both single photon near-infrared fluorescence and two-photon deep red fluorescence in aqueous solution. Org. Biomol. Chem., 2012, 10, 5366-5370.

 Lu Wang and Cong Li. pH responsive fluorescence nanoprobe imaging of tumors by sensing the acidic microenvironment. J. Mater. Chem., 2011, 21, 15862–15871.

Lu Wang, Cong Li. Fluorescence nanoprobe imaging tumor by sensing the acidic microenvironment. Chapter 9. Nanomedicine and Cancer. 2011, Science Publishers: 978-1-57808-727.

Patents

1.         Title: cell permeable fluorogenic probe, Applicants: Kai Johnsson,* Lu Wang,* (*Equal contribution) EP Prio Patent Appilication 18210676.5, Filing data: 06.12.2018, patent PCT pending

2.         Title: pH sensitive Near-Infrared fluorophores for sensing tumor acidic environment. Applicants: Cong Li, Jingye Zhang, Zi Wang, Ziyao Xu, Lu Wang, CN106281306B, Authorization date: 09.08.2019