李和霖,女,于2021年10月入职浙江工业大学绿色制药协同创新中心讲师。2021年博士毕业于德国亚琛工业大学,师从Andrij Pich教授及Felix Plamper教授,此前在德国DWI-莱布尼兹交互材料研究所做科研助理,主要研究方向为抗肿瘤纳米药物递送系统、生物活性抗菌纳米药物载体及纳米生物催化传感系统。在Bioact. Mater.,Adv. Funct. Mater,Biomacromolecules等国际知名期刊发表论文十余篇,申请国际及国内发明专利2项。
代表性论文:
1. X. Li†, H. Li†, C. Zhang, A. Pich*, L. Xing*, X. Shi*, Intelligent Nanogels with Self-Adaptive Responsiveness for Improved Tumor Drug Delivery and Augmented Chemotherapy, Bioact. Mater. 2021, 6 (10), 3473-3484. († Co-first author) (Q1,IF:16.874)
2. X. Li, L. Hetjens, N. Volter, H. Li*, X. Shi*, A. Pich*, Charge-reversible and biodegradable chitosan-based microgels for lysozyme-triggered release of vancomycin. J. Adv. Res. 2022, DOI: 10.1016/j.jare.2022.02.014. (Q1,IF: 12.822)
3. H. Li, X. Li, P. Jain, H. Peng, K. Rahimi, S. Singh, A. Pich*, Dual-Degradable Biohybrid Microgels by Direct Cross-Linking of Chitosan and Dextran Using Azide-Alkyne Cycloaddition.Biomacromolecules 2020, 21 (12), 4933-4944. (Q1,IF: 6.979)
4. H. Li, X. Wu, X. Li*, X. Cao, Y. Li, H. Cao*, Y. Men*, Multistage Extraction of Star Anise and Black Pepper Derivatives for Antibacterial, Antioxidant and Anticancer Activity, Front. Chem. 2021, 9, 660138. (Q2,IF:5.545)
5. H. Li, O. Mergel, P. Jain, X. Li, H. Peng, K. Rahimi, S. Singh, F. Plamper*, A. Pich*, Electroactive and Degradable Supramolecular Microgels, Soft Matter 2019, 15, 8589-8602. (Q2,IF: 4.046)
6. X. Li, H. Sun, H. Li, C. Hu, Y. Luo*, X. Shi*, A. Pich*, Multi-Responsive Biodegradable Cationic Nanogels for Highly Efficient Treatment of Tumors, Adv. Funct. Mater. 2021, 2100227. (Q1,IF:19.924)
7. X. Li, Z. Ouyang, H. Li, C. Hu, P. Saha, L. Xing*, X. Shi*, A. Pich*, Dendrimer-Decorated Nanogels: Efficient Nanocarriers for Biodistribution In Vivo and Chemotherapy of Ovarian Carcinoma,Bioact. Mater. 2021, 6 (10), 3244-3253. (Q1,IF:16.874)
专利:
1. H. Li, X. Cao, Y. Li, X. Li,Preparation and application of supramolecular microgel/drug loaded supramolecular microgel with electroactivity and degradability,国际专利,申请号: PCT/CN2019/111344。
2. 李和霖,曹肖兵,李延军,李鑫,一种具有电活性可降解的超分子微凝胶/载药超分子微凝胶及其制备方法和应用,国内发明专利,授权号: CN201910979825.5。