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成果及论文


代表性论文

(1) Wen Zhang, Jihong Liu, Ping Li,* Xin Wang* and Bo Tang.Reversible Fluorescent Probes for Dynamic Imaging of Liver Ischemia-Reperfusion Injury. Acc. Chem. Res., 2024, 57, 17, 2594–2605.

(2) Xin Wang, Qi Ding, Robin R. Groleau, Luling Wu, Yuantao Mao, Feida Che, Oxana Kotova , Eoin M. Scanlan, Simon E. Lewis,* Ping Li,* Bo Tang,* Tony D. James,* and Thorfinnur Gunnlaugsson.Fluorescent Probes for Disease Diagnosis. Chem. Rev., 2024, 124, 11, 7106-7164.

(3) Hui Wang,† Xiaoting Zhang,† Ping Li,* Fang Huang, Tiancong Xiu, Hongtong Wang, Wei Zhang, Wen Zhang and Bo Tang.* Prediction of Early Atherosclerotic Plaques using a Sequence-Activated Fluorescence Probe for the Simultaneous Detection of γ-Glutamyl Transpeptidase and Hypobromous Acid. Angew. Chem. Int. Ed., 2023, e202315861.

(4) Di Su, Ran Zhang, Xin Wang,* Qi Ding, Feida Che, Zhenzhen Liu, Jingwen Xu, Yuying Zhao, Kunqian Ji, Wei Wu,* Chuanzhu Yan,* Ping Li,* and Bo Tang.* Shedding Light on Lysosomal Malondialdehyde Affecting Vitamin B12 Transport during Cerebral Ischemia/Reperfusion InjuryJ. Am. Chem. Soc., 2023, 145, 22609-22619.

(5) Jihong Liu, Wen Zhang,* Xin Wang, Qi Ding, Chuanchen Wu, Wei Zhang, Luling Wu,* Tony D. James,* Ping Li,* and Bo Tang.Unveiling the Crucial Roles of O2•– and ATP in Hepatic Ischemia–Reperfusion Injury Using Dual-Color/Reversible Fluorescence Imaging. J. Am. Chem. Soc., 2023, 145, 36, 19662-19675.

(6) Jihong Liu, Wen Zhang,* Chunmiao Zhou, Mengmei Li, Xin Wang, Wei Zhang, Zhenzhen Liu, Luling Wu,* Tony D. James,* Ping Li,* and Bo Tang.* Precision Navigation of Hepatic Ischemia Reperfusion Injury Guided by Lysosomal Viscosity-Activatable NIR-Ⅱ Fluorescence. J. Am. Chem. Soc.,  2022, 144, 30, 13586-13599.

(7) Luling Wu,† Jihong Liu,† Xue Tian,† Robin R. Groleau, Beidou Feng, Yonggang Yang, Adam C. Sedgwick, Hai-Hao Han,* Yang Wang, Han-Min Wang, Fang Huang, Steven D. Bull, Hua Zhang,* Chusen Huang,* Yi Zang, Jia Li, Xiao-Peng He, Ping Li,* Bo Tang, Tony D. James,* and Jonathan L. Sessler*. Dual-Channel Fluorescent Probe for the Simultaneous Monitoring of Peroxynitrite and Adenosine-5′-triphosphate in Cellular Applications. J. Am. Chem. Soc., 2022, 144, 174-183.

(8) Luling Wu,,* Jihong Liu,† Ping Li,* Bo Tang* and Tony D. James*, Two-photon small-molecule fluorescence-based agents for sensing, imaging, and therapy within biological systems. Chem. Soc. Rev., 2021, 50, 702-734.

(9) Qi Ding,† Ying Tian,† Xin Wang,* Ping Li,* Di Su, Chuanchen Wu, Wen Zhang, and Bo Tang*. Oxidative Damage of Tryptophan Hydroxylase‑2 Mediated by Peroxisomal Superoxide Anion Radical in Brains of Mouse with Depression. J. Am. Chem. Soc.2020, 142, 20735-20743.

(10) Haibin Xiao,† Wen Zhang,† Ping Li,* Wei Zhang, Xin Wang, and Bo Tang*. Versatile fluorescent probes for visualizing superoxide anion in living cells and in vivo. Angew. Chem. Int. Ed., 2020, 132, 4244-4258.

(11) Xin Wang, Ping Li,* Qi Ding, Chuanchen Wu, Wen Zhang and Bo Tang*. Observation of Acetylcholinesterase in Stress-induced Depression Phenotypes by Two-photon Fluorescence Imaging in the Mouse Brain. J. Am. Chem. Soc., 2019, 141(5): 2061-2068.

(12) Xin Wang, Ping Li,* Qi Ding, Chuanchen Wu, Wen Zhang, and Bo Tang*. Illuminating the Function of the Hydroxyl Radical in the Brains of Mice with Depression Phenotypes by Two‐Photon Fluorescence Imaging. Angew. Chem. Int. Ed., 2019, 58, 4674-4678.

(13) Wei Zhang, Jun Lu, Xiaonan Gao, Ping Li,* Wen Zhang, Yu Ma, Hui Wang and Bo Tang*. Enhanced Photodynamic Therapy by Reduced Levels of Intracellular Glutathione Obtained By Employing a Nano-MOF with CuII as Active Center. Angew. Chem. Int. Ed., 2018, 57, 4891-4896.

(14) Ping Li, Lu Liu, Haibin Xiao, Wei Zhang, Lulin Wang, and Bo Tang*. A New Polymer Nanoprobe Based on Chemiluminescence Resonance Energy Transfer (CRET) for Ultrasensitive Imaging of Intrinsic Superoxide Anion in Mice. J. Am. Chem. Soc., 2016, 138, 2893-2896.

(15) Wei Zhang, Wei Liu, Ping Li,* Haibin Xiao, Hui Wang, and Bo Tang*. A Fluorescence Nanosensor for Glycoproteins with Activity Based on the Molecularly Imprinted Spatial Structureof the Target and Boronate Affinity. Angew. Chem. Int. Ed., 2014, 53, 12489-12493.

(16) Wen Zhang,† Ping Li,† Fan Yang, Xiufen Hu, Chuanzhi Sun, Wei Zhang, Dezhan Chen, and Bo Tang*. Dynamic and Reversible Fluorescence Imaging of Superoxide Anion Fluctuations in Live Cells and in Vivo. J. Am. Chem. Soc., 2013, 135, 14956-14959.


主要论文

2024年

(122) Jihong Liu, Dongni Yin, Wen Zhang, Xin Wang, Tony D. James, Ping Li* and Bo Tang. A multifunctional “three-in-one” fluorescent theranostic system for hepatic ischemia–reperfusion injury. Chem. Sci., 2024, 10.1039/d4sc04962d

(121) Feida CheXiaoming ZhaoQi DingXiwei LiWen ZhangPing Li,* Xin Wang* and Bo Tang. A versatile fluorescent probe for hydrogen peroxide in serotonergic neurons of living brains of mice with depression. J. Mater. Chem. B, 2024, 12, 10241-10247

(120) Wen Zhang, Min Zhang, Mengmei Li, Xin Wang, Ping Li* and Bo Tang.Glutathione and viscosity double-locked response fluorescent probe for imaging and surgical navigation of hepatocellular carcinoma. Chem. Commun., 2024, 60, 10021-10024. 

(119) Wen Zhang, Jihong Liu, Ping Li,* Xin Wang* and Bo Tang.Reversible Fluorescent Probes for Dynamic Imaging of Liver Ischemia-Reperfusion Injury. Acc. Chem. Res., 2024, 57, 17, 2594–2605.

(118) Xin Wang, Qi Ding, Robin R. Groleau, Luling Wu, Yuantao Mao, Feida Che, Oxana Kotova , Eoin M. Scanlan, Simon E. Lewis,* Ping Li,* Bo Tang,* Tony D. James,* and Thorfinnur Gunnlaugsson.Fluorescent Probes for Disease Diagnosis. Chem. Rev., 2024, 124, 11, 7106-7164.

(117) Yuantao Mao, Chuanchen Wu, Xin Wang,* Fanghui Zhang, Xinru Qi, Xia Li, Ping Li* and Bo Tang.* Fluorescence Imaging Sheds Light on the Immune Evasion Mechanisms of Hepatic Stellate Cells Mediated by Superoxide Anion. Commun. Biol., 2024, 7, 558.

(116) Chuanchen Wu, Yuantao Mao, Xinru Qi, Xin Wang, Ping Li,* Wen Zhang, and Bo Tang.Tracking Interactions between TAMs and CAFs Mediated by Arginase‐Induced Proline Production During Immune Evasion of HCCAggregate, 2024, e530.

(115) Jin LiJiheng XuRuize ZhaoWei ZhangPing Li, Wen ZhangHui Wang, and Bo Tang.* Progress of Fluorescent Probes for Protein Phosphorylation and Glycosylation in Atherosclerosis. Chem. Eur. J., 2024, e202303778.

(114) Hui Wang,* Xiaoting Zhang, Tiancong Xiu, Hongtong Wang, Ping Li,* and Bo Tang.* Fluorescence Probes for Sensing and Imaging within Golgi Apparatus. Coordin. Chem. Rev., 2024, 502, 215618.

(113) Hui Wang,* Na Wen, Ping Li,* Tiancong Xiu, Shuqi Shang, Wei Zhang, Wen Zhang, Junnan Qiao, and Bo Tang.* Treatment Evaluation of Rheumatoid Arthritis by in Situ Fluorescence Imaging of the Golgi Cysteine. Talanta, 2024, 270, 125532.

2023年

(112) Jun Lu, Zongying Li, Mengmeng LuNannan FanWei Zhang,* Ping LiYue Tang,* Xia YinWen ZhangHui WangBo Tang.* Assessing early Atherosclerosis by Detecting and Imaging of Hypochlorous Acid and Phosphorylation using Fluorescence Nanoprobe. Adv. Mater., 2023, 2307008

(111) Hui Wang,† Xiaoting Zhang,† Ping Li,* Fang Huang, Tiancong Xiu, Hongtong Wang, Wei Zhang, Wen Zhang, Bo Tang.* Prediction of Early Atherosclerotic Plaques using a Sequence-Activated Fluorescence Probe for the Simultaneous Detection of γ-Glutamyl Transpeptidase and Hypobromous Acid. Angew. Chem. Int. Ed., 2023, e202315861.

(110) Xin Wang, Feida Che, Xin Zhang, Ping Li,* Wen Zhang, and Bo Tang.* Tracing Superoxide Anion in Serotonergic Neurons of Living Mouse Brains with Depression by Small-Molecule Fluorescence Probes. Anal. Chem., 2023, 95, 42, 15614-15620. 

(109) Di Su, Ran Zhang, Xin Wang,* Qi Ding, Feida Che, Zhenzhen Liu, Jingwen Xu, Yuying Zhao, Kunqian Ji, Wei Wu,* Chuanzhu Yan,* Ping Li,* and Bo Tang.* Shedding Light on Lysosomal Malondialdehyde Affecting Vitamin B12 Transport during Cerebral Ischemia/Reperfusion Injury. J. Am. Chem. Soc., 2023, 145, 22609-22619.

(108) Xiaoting Zhang, Tiancong Xiu, Hui WangHongtong WangPing Li,* and Bo Tang.Recent progress in the development of small-molecule double-locked logic gate fluorescence probes. Chem. Commun.2023,59, 11017-11027.

(107) Di Su, Ran Zhang, Xin Wang,* Qi Ding, Feida Che, Wen Zhang, Wei Wu,* Ping Li,* and Bo Tang.A New Multi-Parameter Imaging Platform for in Vivo Drug Efficacy Evaluation of Ischemic Stroke. Talanta, 2024, 266125133.

(106) Jihong Liu, Wen Zhang,* Xin Wang, Qi Ding, Chuanchen Wu, Wei Zhang, Luling Wu,* Tony D. James,* Ping Li,* and Bo Tang.Unveiling the Crucial Roles of O2•– and ATP in Hepatic Ischemia-Reperfusion Injury Using Dual-Color/Reversible Fluorescence Imaging. J. Am. Chem. Soc.2023, 145, 36, 19662-19675.

(105) Wen Zhang, Wenjie Fan, Xin Wang, Ping Li,* Wei Zhang, Hui Wang, and Bo Tang.* Uncovering Endoplasmic Reticulum Superoxide Regulating Hepatic Ischemia-Reperfusion Injury by Dynamic Reversible Fluorescence Imaging. Anal. Chem. 2023, 95, 21, 8367-8375.

(104) Chuanchen Wu, Yuantao Mao, Fanghui Zhang, Xin Wang, Nannan Fan, Wen Zhang, Ping Li,* and Bo Tang.* Uncovering the Mechanism of Cancer-Associated Fibroblasts Induced Immune Evasion of Hepatocellular Carcinoma Cells via in Situ Fluorescence Imaging. Sensor. Actuat. B-Chem., 2023, 389, 15, 133891.

(103) Ning Wen, Jin Li, Wei Zhang,* Ping Li, Xia Yin, Wen Zhang, Hui Wang, and Bo Tang.* Monitoring the Progression of Early Atherosclerosis Using a Fluorescence Nanoprobe for the Detection and Imaging of Phosphorylation and Glucose Levels. Angew. Chem. Int. Ed., 2023, e202302161.

(102) Kai Wang, Ruixiao Zhang, Xiujie Zhao,* Yan Ma, Lijuan Ren, Youxiao Ren, Gaofei Chen, Dingming Ye, Jinfang Wu, Xinyuan Hu, Yuanqiang Guo, Rimo Xi, Meng Meng, Qingqiang Yao,* Ping Li,* Qixin Chen,* and Tony D. James.* Reversible Recognition-Based Boronic Acid Probes for Glucose Detection in Live Cells and Zebrafish. J. Am. Chem. Soc.,  2023, 145, 15, 8408-8416.

(101) Wen Zhang, Mengmei Li, Xin Wang, Wei Zhang, Hui Wang, Ping Li,* and Bo Tang.* Precision Navigation of Venous Thrombosis Guided by Viscosity-Activatable Near-Infrared FluorescenceAnal. Chem., 2023, 95, 4, 2382-2389. 

(100) Jin Li, Na Zhao, Wei Zhang,* Ping Li, Xia Yin, Wen Zhang, Hui Wang, and Bo Tang.* Assessing the Progression of Early Atherosclerosis Mice Using a Fluorescence Nanosensor for the Simultaneous Detection and Imaging of pH and Phosphorylation. Angew. Chem. Int. Ed., 2023, 62, 3, e202215178.

2022

(99) Hanchuang Zhu, Pan Jia, Xin Wang, Ying Tian, Caiyun Liu, Xiwei Li, Kun Wang, Ping Li,* Baocun Zhu*, and Bo Tang*. In Situ Observation of Lysosomal Hypobromous Acid Fluctuations in the Brain of Mice with Depression Phenotypes by Two-Photon Fluorescence Imaging. Anal. Chem. 2022, 94, 34, 11783-11790.

(98) Fuyan Tang,† Chuanchen Wu,† Zhaodong Zhai, Kai Wang, Xueli Liu, Haibin Xiao,* Shuping Zhuo,* Ping Li,* and Bo Tang. Recent progress in small-molecule fluorescent probes for endoplasmic reticulum imaging in biological systems. Analyst, 2022,147, 987-1005.

(97) Wen Zhang,† Chunmiao Zhou,† Ping Li,* Jihong Liu, Xin Wang, Wei Zhang, Hui Wang, and Bo Tang*. Quantitative Fluorescence Imaging of the Intracellular Redox State by Real-Time Spatial and Temporal Simultaneous Analysis of O2•− Levels and Keap1 Translocation. Anal. Chem., 2022, 94, 36, 12352-12359.

(96) Wen Zhang,† Mengmei Li,† Xin Wang, Ping Li,* and Bo Tang*. Application of Near-Infrared Fluorescence Imaging in Thrombosis Detection. Anal. Sens., 2022, e202200045.

(95) Xin Wang,† Di Su,† Chunyu Liu, Ping Li,* Ran Zhang, Wen Zhang, Wei Zhang, and Bo Tang*. Janus-Faced Fluorescence Imaging Agent for Malondialdehyde and Formaldehyde in Brains. Anal. Chem., 2022, 94, 43, 14965-14973.

(94) Hui Wang, Junwei Nie, Ping Li,* Xiaoting Zhang, Yu Wang, Wei Zhang, Wen Zhang, and Bo Tang*. Exploring Idiopathic Pulmonary Fibrosis Biomarker by Simultaneous Two-Photon Fluorescence Imaging of Cysteine and Peroxynitrite. Anal. Chem., 2022, 94, 32, 11272-11281.

(93) Jihong Liu, Wen Zhang,* Chunmiao Zhou, Mengmei Li, Xin Wang, Wei Zhang, Zhenzhen Liu, Luling Wu,* Tony D. James,* Ping Li,* and Bo Tang.* Precision navigation of hepatic ischemia reperfusion injury guided by lysosomal viscosity-activatable NIR-Ⅱ fluorescence. J. Am. Chem. Soc., 2022, 144, 30, 13586-13599.

(92) Nannan Fan, Yongqing Zhou, Lijie Wu, Xin Wang, Ping Li,* Zhenzhen Liu, Wen Zhang, Wei Zhang, Bo Tang*. Probing Iron-Mediated Synergistic Change of Cl− and HClO in Liver Cancer Cells with a Dual-Color Fluorescence Reporter. Anal. Chem., 2022, 94, 30, 10659–10668.

(91) Li Yang,‡ Mengqi Wang,‡ Xiaoyu Gu,‡ Wei Zhang,* Ping Li, Wen Zhang, Hui Wang and Bo Tang*, One-step synthesis of carbon dots-based fluorescence sensor for two-photon imaging of pH in diabetic mice. Front. Chem. Sci. Eng. 2022, Accepted.

(90) Nannan Fan, Ping Li,* Yongqing Zhou, Chuanchen Wu, Xin Wang, Zhenzhen Liu, Bo Tang*. Demystifying Lysosomal α-L-Fucosidase in Liver Cancer-Bearing Mice by Specific Two-Photon Fluorescence Imaging. ACS Sensors, 2022, 7, 71-81.

(89) Xin Wang,‡ Ruiyuan Wang,‡ Qi Ding, Wei Wu,* Feida Che, Ping Li,* Wen Zhang, Wei Zhang, Zhenzhen Liu, and Bo Tang.* Hypochlorous Acid-Activated Multifunctional Fluorescence Platform for Depression Therapy and Antidepressant Efficacy Evaluation. Anal. Chem., 2022, 94, 27, 9811–9818.

(88) Hui Wang,‡* Cuifang Liu,‡ Xiaoting Zhang, Tiancong XiuPing Li,* Wei Zhang, Wen Zhang, Xin Wang, Zhenzhen Liu, Bo Tang*. Simultaneous fluorescence imaging of Golgi O2•−and Golgi H2O2 in mice with hypertension. Biosens. Bioelectron., 2022, 213, 114480.

(87) Xue Wang,† Jin Li,† Wei Zhang,* Ping Li, Wen Zhang, Hui Wang, and Bo Tang* Evaluating diabetic ketoacidosis via a MOF sensor for fluorescence imaging of phosphate and pH, Chem. Commun., 2022, 58, 3023-3026.

(86) Wei Zhang, Jin Li, Na Zhao, Ping Li, Wen Zhang, Hui Wang, Bo Tang* Ratiometric fluorescence biosensor for imaging of protein phosphorylation levels in atherosclerosis mice. Anal. Chim. Acta, 2022, 1208, 339825.

(85) Xin Wang,‡ Qi Ding,‡ Ying Tian, Wei Wu,* Feida Che, Ping Li,* Wen Zhang, Wei Zhang and Bo Tang*. In situ fluorescence imaging reveals that mitochondrial H2O2 mediates lysosomal dysfunction in depression. Chem. Commun., 2022, 58, 6320–6323.

(84) Luling Wu,† Jihong Liu,† Xue Tian,† Robin R. Groleau, Beidou Feng, Yonggang Yang, Adam C. Sedgwick, Hai-Hao Han,* Yang Wang, Han-Min Wang, Fang Huang, Steven D. Bull, Hua Zhang,* Chusen Huang,* Yi Zang, Jia Li, Xiao-Peng He, Ping Li,* Bo Tang, Tony D. James,* and Jonathan L. Sessler*. Dual-Channel Fluorescent Probe for the Simultaneous Monitoring of Peroxynitrite and Adenosine-5′-triphosphate in Cellular Applications. J. Am. Chem. Soc., 2022, 144, 174-183.

(83) Yongqing Zhou, Wen Zhang,* Xin Wang, Ping Li,* Bo Tang.* Recent Progress in Small-Molecule Fluorescence and Photoacoustic Dual-Modal Probes for the In-Vivo Detection of Bioactive Molecules. Chemistry-An Asian Journal, 2022, 17, 10, e202200155.

(82) Di Su, Xin Wang, Wen Zhang, Ping Li*, Bo Tang*. Fluorescence imaging for visualizing the bioactive molecules of lipid peroxidation within biological systems. Trend. Anal. Chem., 2022, 146,116484.

(81) Chuanchen Wu,† Yuantao Mao,† Xin Wang, Ping Li,* and Bo Tang*. Deep-Tissue Fluorescence Imaging Study of Reactive Oxygen Species in a Tumor Microenvironment. Anal. Chem., 2022, 94, 165-176.

(80) Jun Lu, Zhongyao Jiang, Jie Ren, Wei Zhang,* Ping Li, Zhenzhen Chen, Wen Zhang, Hui Wang, and Bo Tang* One-Pot Synthesis of Multifunctional Carbon-Based Nanoparticle-supported Dispersed Cu2+ Disrupts Redox Homeostasis to Enhance CDT. Angew. Chem. Int. Ed. 2022, 61, e202114373.

(79) Yongqing Zhou, Xin Wang, Wei Zhang*, Bo Tang, Ping Li*. Recent advances in small molecule fluorescent probes for simultaneous imaging of two bioactive molecules in live cells and in vivoFront. Chem. Sci. Eng., 2022, 16, 4-33.

2021

(78) Hui Wang,†* Xiaoting Zhang,† Mingyan Dong, Wei Zhang, Wen Zhang, Ping Li,* and Bo Tang. Evaluation of Effectiveness of Antiarthritic Treatment by in situ Ratiometric Fluorescence Imaging of the Endoplasmic Reticulum pH. Sensors and Actuators B: Chemical, 2021, 349, 130786.

(77) Hui Wang,a Xin Wang,a Ping Li,*a Mingyan Dong,a Shao Q. Yao *b and Bo Tang *a. Fluorescent probes for visualizing ROS-associated proteins in disease. Chem. Sci., 2021, 12, 11620-11646.

(76) Zhenzhen Liu†, Xiaoning Liu†, RuiCheng Fan†, Yuping Jia†, Qingke Zhang, Xin qing Gao, Yu-Qing Wang, Yu-Qing Wang, Meng-Qing Yang, Li-Zhen Ji, Yong Qing Zhou, Hong Li Li*, Ping Li*, Bo Tang*. Identification of pimavanserin tartrate as a potent Ca2+-calcineurin-NFAT pathway inhibitor for glioblastoma therapy. Acta Pharmacol Sin. 2021, 42, 1860-1874.

(75) Wei Zhang, Jie Ren, Jun Lu, Ping Li, Wen Zhang, Hui Wang, and Bo Tang*. Elucidating the Relationship between ROS and Protein Phosphorylation through In Situ Fluorescence Imaging in the Pneumonia Mice. Anal. Chem., 2021, 93, 31, 10907–10915.

(74) Hui Wang*,1, Hongtong Wang1, Xiaoting Zhang, Mingyan Dong, Fang Huang*, Ping Li*, Bo Tang. A two-photon fluorescent probe for imaging of mitochondrial cysteine in λ-carrageenan induced arthritis. Sensors and Actuators B: Chemical, 2021, 338, 129749.

(73) Yongqing Zhou, Chuanchen Wu, Xin Wang, Ping Li*, Nannan Fan, Wei Zhang, Zhenzhen Liu, Wen Zhang, Bo Tang*. Exploring the Changes of Peroxisomal Polarity in the Liver of Mice with Nonalcoholic Fatty Liver Disease. Anal. Chem., 2021, 93, 9609-9620.

(72) Hui Wang, Mingyan Dong, Hongtong Wang, Fang Huang, Ping Li,* Wei Zhang, Wen Zhang and Bo Tang*. Ultrasensitive and ratiometric two-photon fluorescence imaging of Golgi polarity during drug-induced acute kidney injury. Chem. Commun., 2021, 57, 5838–5841.

(71) Nannan Fan, Chuanchen Wu, Yongqing Zhou, Xin Wang, Ping Li,* Zhenzhen Liu, and Bo Tang*. Rapid Two-Photon Fluorescence Imaging of Monoamine Oxidase B for Diagnosis of Early-Stage Liver Fibrosis in Mice. Anal. Chem. 2021, 93, 7110-7117.

(70) Yongqing Zhou, Zhenzhen Liu, Guangming Qiao, Bo Tang, Ping Li.* Visualization of endoplasmic reticulum viscosity in the liver of mice with nonalcoholic fatty liver disease by a near-infrared fluorescence probe. Chin. Chem. Lett.2021. 32, 3641-3645.

(69) Hui Wang,† Cuifang Liu,† Zixu He, Ping Li,* Wei Zhang, Wen Zhang, and Bo Tang*. Dual-Colored Fluorescence Imaging of Mitochondrial HNO and Golgi-HNO in Mice with DILI. Anal. Chem., 2021, 93, 6551–6558.

(68) Wen Zhang, Simin Bi, Ping Li,* Jihong Liu, Chunmiao Zhou, Xin Wang, Wei Zhang, Hui Wang, and Bo Tang*. In Situ Observation of mtDNA Damage during Hepatic Ischemia-Reperfusion. Anal. Chem. 2021, 93, 14, 5782–5788.

(67) Luling Wu,†,* Jihong Liu,† Ping Li,* Bo Tang* and Tony D. James*, Two-photon small-molecule fluorescence-based agents for sensing, imaging, and therapy within biological systems. Chem. Soc. Rev., 2021, 50, 702-734.

(66) Nannan Fan, Ping Li,* Chuanchen Wu, Xin Wang, Yongqing Zhou, and Bo Tang*. ALP-Activated Chemiluminescence PDT Nano-Platform for Liver Cancer-Specific Theranostics. ACS Appl. Bio Mater. 2021, 4, 1740-1748.

(65) Haibin Xiao, Ping Li,* Bo Tang. Recent progresses in fluorescent probes for detection of polarity. Coordin. Chem. Rev., 2021, 427, 213528.

(64) Luling Wu,† Jihong Liu,† Xue Tian, Robin R. Groleau, Steven D. Bull, Ping Li,* Bo Tang*, Tony D. James*. Fluorescent probe for the imaging of superoxide and peroxynitrite during drug-induced liver injury. Chem. Sci., 2021, 12, 3921-3928.

2020

(63) Qi Ding,† Ying Tian,† Xin Wang,* Ping Li,* Di Su, Chuanchen Wu, Wen Zhang, and Bo Tang*. Oxidative Damage of Tryptophan Hydroxylase‑2 Mediated by Peroxisomal Superoxide Anion Radical in Brains of Mouse with Depression. J. Am. Chem. Soc., 2020, 142, 20735–20743.

(62) Wei Zhang, Hui Zhang, Mengqi Wang, Ping Li, Caifeng Ding, Wen Zhang, Hui Wang, and Bo Tang*. Copolymer-Based Fluorescence Nanosensor for In Situ Imaging of Homocysteine in the Liver and Kidney of Diabetic Mice. Anal. Chem., 2020, 92, 16221-16228.

(61) Yongqing Zhou, Ping Li,* Xin Wang, Chuanchen Wu, Nannan Fan, Xiaoning Liu, Lijie Wu, Wei Zhang, Wen Zhang, Zhenzhen Liu and Bo Tang*. In situ visualization of peroxisomal viscosity in the liver of mice with non-alcoholic fatty liver disease by near-infrared fluorescence and photoacoustic imaging. Chem. Sci., 2020, 11, 12149.

(60) Xin Wang,† Xiaoyi Bai,† Di Su, Yandi Zhang, Ping Li,* Shuyi Lu, Yulin Gong, Wen Zhang, and Bo Tang*. Simultaneous Fluorescence Imaging Reveals N‑Methyl‑D‑aspartic Acid Receptor Dependent Zn2+/H+ Flux in the Brains of Mice with Depression. Anal. Chem., 2020, 92, 4101−4107.

(59) Wei Zhang, Xiaolei Liu, Ping Li, Wen Zhang, Hui Wang, and Bo Tang*. In Situ Fluorescence Imaging of the Levels of Glycosylation and Phosphorylation by a MOF-Based Nanoprobe in Depressed Mice. Anal. Chem., 2020, 92, 3716−3721.

(58) Hui Wang,*,† Yuyun Yang,† Fang Huang, Zixu He, Ping Li,* Wei Zhang, Wen Zhang, and Bo Tang*. In Situ Fluorescent and Photoacoustic Imaging of Golgi pH to Elucidate the Function of Transmembrane Protein 165. Anal. Chem., 2020, 92, 3103−3110.

(57) Di Su,† Ping Li,† Xin Wang, Wei Zhang, Yandi Zhang, Chuanchen Wu, Wen Zhang, Yan Li, Wenjun Tai, and Bo Tang*. Observing Malondialdehyde-Mediated Signaling Pathway in Cerebral Ischemia Reperfusion Injury with a Specific Nanolight. Anal. Chem., 2020, 92, 2748-2755.

(56) Jiheng Xu,† Hui Zhang,† Wei Zhang*, Ping Li, Wen Zhang, Hui Wang and Bo Tang*. Fluorescence nanosensor for in situ detection of phosphate and alkaline phosphatase in parathyroid dysfunction mice. Chem. Commun., 2020, 56, 2431-2434.

(55) Lijie Wu,† Qi Ding,† Xin Wang, Ping Li,* Nannan Fan, Yongqing Zhou, Lili Tong, Wen Zhang, Wei Zhang, and Bo Tang*. Visualization of Dynamic Changes in Labile Iron (Ⅱ) Pools in Endoplasmic Reticulum Stress-Mediated Drug-Induced Liver Injury. Anal. Chem., 2020, 92, 1245-1251.

(54) Haibin Xiao,† Wen Zhang,† Ping Li,* Wei Zhang, Xin Wang, and Bo Tang*. Versatile fluorescent probes for visualizing superoxide anion in living cells and in vivo. Angew. Chem. Int. Ed., 2020, 132, 4244-4258.

2019

(53) Chuanchen Wu,† Ping Li, Nannan Fan, Jianjun Han, Wei Zhang, Wen Zhang, and Bo Tang*. A Dual-Targeting Functionalized Graphene Film for Rapid and Highly Sensitive Fluorescence Imaging Detection of Hepatocellular Carcinoma Circulating Tumor Cells. ACS Appl. Mater. Inter., 2019, 11, 44999-45006.

(52) Hui Wang,† Zixu He,† Yuyun Yang, Jiao Zhang, Wei Zhang, Wen Zhang, Ping Li* and Bo Tang*. Ratiometric Fluorescence Imaging of Golgi H₂O₂ Reveals a Correlation between Golgi Oxidative Stress and Hypertension. Chem. Sci., 2019, 10, 10876-10880.

(51) Wen Zhang,† Jihong Liu,† Ping Li,* Xin Wang, Simin Bi, Jiao Zhang, Wei Zhang, Hui Wang, and Bo Tang*. In situ and real-time imaging of superoxide anion and peroxynitrite elucidating arginase 1 nitration aggravating hepatic ischemia-reperfusion injury. Biomaterials, 2019, 225, 119499.

(50) Wen Zhang,† Di Su,† Ping Li,* Jiao Zhang, Jihong Liu, Hui Wang, Wei Zhang and Bo Tang*. Two-photon fluorescence imaging of mitochondrial superoxide anion transport mediating liver ischemia-reperfusion injury in mice. Chem. Commun., 2019, 55, 10740-10743.

(49) Jun Lu, Wei Zhang*, Ping Li, Xiaonan Gao, Wen Zhang, Hui Wang and Bo Tang*. Photodynamic therapy for hypoxic solid tumors via Mn-MOF as a photosensitizer. Chem. Commun., 2019, 55, 10792-10795.

(48) Hui Wang,† Yixin Zhang,† Yuyun Yang, Zixu He, Chuanchen Wu, Wei Zhang, Wen Zhang, Ju Liu, Ping Li* and Bo Tang*. In situ photoacoustic imaging of cysteine to reveal the mechanism of limited GSH synthesis in pulmonary fibrosis. Chem. Commun., 2019, 55, 9685-9688.

(47) Yandi Zhang,† Xin Wang,† Xiaoyi Bai, Ping Li,* Di Su, Wen Zhang, Wei Zhang, and Bo Tang*. Highly Specific Cys Fluorescence Probe for Living Mouse Brain Imaging via Evading Reaction with Other Biothiols. Anal. Chem., 2019, 91, 8591-8594.

(46) Yongqing Zhou,† Ping Li,† Nannan Fan, Xin Wang, Xiaoning Liu, Lijie Wu, Wen Zhang, Wei Zhang, Changle Ma* and Bo Tang*. In situ visualization of peroxisomal peroxynitrite in liver of mice with acute liver injury induced by carbon tetrachloride using a new two-photon fluorescent probe. Chem. Commun., 2019, 55, 6767-6770.

(45) Ping Li,† Xiaomeng Guo,† Xiaoyi Bai, Xin Wang, Qi Ding, Wen Zhang, Wei Zhang, and Bo Tang*. Golgi Apparatus Polarity Indicates Depression-like Behaviours of Mice Using in vivo Fluorescence Imaging. Anal. Chem., 2019, 91, 3382-3388.

(44) Ping Li,† Jijuan Wang,† Xin Wang, Qi Ding, Xiaoyi Bai, Yandi Zhang, Di Su, Wei Zhang, Wen Zhang and Bo Tang*. In situ visualization of ozone in the brains of mice with depression phenotypes by using a new near-infrared fluorescence probe. Chem. Sci., 2019, 10, 2805-2810.

(43) Wen Zhang,† Jiao Zhang,† Ping Li,* Jihong Liu, Di Su and Bo Tang*. Two-photon fluorescence imaging reveals a Golgi apparatus superoxide anion-mediated hepatic ischaemia-reperfusion signalling pathway. Chem. Sci., 2019, 10, 879-883.

(42) Ping Li,*† Xiaohui Shi,† Haibin Xiao, Qi Ding, Xiaoyi Bai, Chuanchen Wu, Wen Zhang and Bo Tang*. Two-photon imaging of the endoplasmic reticulum thiol flux in the brains of mice with depression phenotypes. Analyst, 2019, 144, 191-196.

(41) Xin Wang; Ping Li,* Qi Ding; Chuanchen Wu; Wen Zhang; Bo Tang*. Observation of Acetylcholinesterase in Stress-induced Depression Phenotypes by Two-photon Fluorescence Imaging in the Mouse Brain. J. Am. Chem. Soc., 2019, 141(5): 2061~2068.

(40) Xin Wang, Ping Li,* Qi Ding, Chuanchen Wu, Wen Zhang, and Bo Tang*. Illuminating the Function of the Hydroxyl Radical in the Brains of Mice with Depression Phenotypes by Two‐Photon Fluorescence Imaging. Angew. Chem. Int. Ed., 2019, 58, 4674-4678.

2018

(39) Xueting Liu,† Nannan Fan,† Lijie Wu, Chuanchen Wu, Yongqing Zhou, Ping Li* and Bo Tang*. Lighting up alkaline phosphatase in drug-induced liver injury using a new chemiluminescence resonance energy transfer nanoprobe. Chem. Commun., 2018, 54, 12479-12482.

(38) Haibin Xiao,† Ruilin Zhang,† Chuanchen Wu, Ping Li,* Wen Zhang*, Bo Tang. A new pH-sensitive fluorescent probe for visualization of endoplasmic reticulum acidification during stress. Sensor Actuat B-Chem., 2018, 273, 1754-1761.

(37) Wei Zhang*, Jiheng Xu, Ping Li, Xiaonan Gao, Wen Zhang, Hui Wang and Bo Tang*. Treatment of hyperphosphatemia based on specific interaction between phosphorus and active center Zr(IV) of nano-MOFs. Chem. Sci., 2018, 9, 7483-7487.

(36) Wei Zhang, Jun Lu, Xiaonan Gao, Ping Li,* Wen Zhang, Yu Ma, Hui Wang, Bo Tang*. Enhanced Photodynamic Therapy by Reduced Levels of Intracellular Glutathione Obtained By Employing a Nano-MOF with CuII as Active Center. Angew. Chem. Int. Ed., 2018, 57, 4891-4896.

(35) Haibin Xiao, Chuanchen Wu, Ping Li,* and Bo Tang*. Simultaneous Fluorescence Visualization of Endoplasmic Reticulum Superoxide Anion and Polarity in Myocardial Cells and Tissue. Anal. Chem., 2018, 90, 6081-6088.

(34) Wei Zhang*, Ruixia Wang, Wei Liu, Xin Wang, Ping Li,* Wen Zhang, Hui Wang and Bo Tang*. Te-containing carbon dots for fluorescence imaging of superoxide anion in mice during acute strenuous exercise or emotional changes. Chem. Sci., 2018, 9, 721-727.

2017

(33) Wei Zhang, Jiaoyang Wang, Ping Li,* Chuanchen Wu, Hongyan Zhang, Wen Zhang, Hui Wang and Bo Tang*. Transferrin-navigation Nano Artificial Antibody Fluorescence Recognition of Circulating Tumor Cells. Sci. Rep., 2017, 7,10142.

(32) Haibin Xiao, Chuanchen Wu, Ping Li,* Wen Gao, Wen Zhang, Wei Zhang, Lili Tong and Bo Tang*. Ratiometric photoacoustic imaging of endoplasmic reticulum polarity in injured liver tissues of diabetic mice. Chem. Sci., 2017, 8, 7025-7030.

(31) Wen Zhang, Xin Wang, Ping Li,* Haibin Xiao, Wei Zhang, Hui Wang, and Bo Tang*. Illuminating Superoxide Anion and pH Enhancements in Apoptosis of Breast Cancer Cells Induced by Mitochondrial Hyperfusion Using a New Two-Photon Fluorescence Probe. Anal. Chem., 2017, 89, 6840-6845.

(30) Haibin Xiao, Xiao Liu, Chuanchen Wu, Yaohuan Wu, Ping Li,* Xiaomeng Guo, Bo Tang*. A new endoplasmic reticulum-targeted two-photon fluorescent probe for imaging of superoxide anion in diabetic mice. Biosens. Bioelectron., 2017, 91, 449-455.

2016

(29) Ping Li, Lu Liu, Haibin Xiao, Wei Zhang, Lulin Wang, and Bo Tang*. A New Polymer Nanoprobe Based on Chemiluminescence Resonance Energy Transfer (CRET) for Ultrasensitive Imaging of Intrinsic Superoxide Anion in Mice. J. Am. Chem. Soc., 2016, 138, 2893-2896.

(28) Baocun Zhu,† Ping Li,† Wei Shu, Xin Wang, Caiyun Liu, Yue Wang, Zuokai Wang, Yawei Wang, and Bo Tang*. Highly Specific and Ultrasensitive Two-photon Fluorescence Imaging of Native HOCl in Lysosomes and Tissues Based on Thiocarbamate Derivatives. Anal. Chem., 2016, 88,12532-12538.

(27) Wei Zhang, Junqing Kang, Ping Li,* Lu Liu, Hui Wang and Bo Tang*. Two-photon fluorescence imaging of sialylated glycans in vivo based on a sialic acid imprinted conjugated polymer nanoprobe. Chem. Commun., 2016, 52, 13991-13994.

(26) Haibin Xiao, Ping Li,* Shan Zhang, Wei Zhang, Wen Zhang and Bo Tang*. Simultaneous fluorescence visualization of mitochondrial hydrogen peroxide and zinc ions in live cells and in vivo. Chem. Commun., 2016, 52, 12741-12744.

(25) Haibin Xiao, Ping Li,* Xiufen Hu, Xiaohui Shi, Wen Zhang and Bo Tang*. Simultaneous fluorescence imaging of hydrogen peroxide in mitochondria and endoplasmic reticulum during apoptosis. Chem. Sci., 2016, 7, 6153-6159.

(24) Haibin Xiao,† Ping Li,† Wei Zhang and Bo Tang*. An ultrasensitive near-infrared ratiometric fluorescent probe for imaging mitochondrial polarity in live cells and in vivo. Chem. Sci., 2016, 7, 1588-1593.

2015

(23) Wei Zhang, Wei Liu, Ping Li,* Fang Huang, Hui Wang, and Bo Tang*. Rapid-Response Fluorescent Probe for Hydrogen Peroxide in Living Cells Based on Increased Polarity of C-B Bonds. Anal. Chem., 2015, 87, 9825-9828.

(22) Wei Zhang, Junqing Kang, Ping Li,* Hui Wang, and Bo Tang*. Dual Signaling Molecule Sensor for Rapid Detection of Hydrogen Sulfide Based on Modified Tetraphenylethylene. Anal. Chem., 2015, 87, 8964-8969.

(21) Lu Li,† Ping Li,† Juan Fang, Qingling Li, Haibin Xiao, Hui Zhou, and Bo Tang*. Simultaneous Quantitation of Na+ and K+ in Single Normal and Cancer Cells Using a New Near-Infrared Fluorescent Probe. Anal. Chem., 2015, 87, 6057-6063.

(20) Wei Zhang, Wei Liu, Ping Li,* Junqing Kang, Jiaoyang Wang, Hui Wang and Bo Tang*. Reversible two-photon fluorescent probe for imaging of hypochlorous acid in live cells and in vivo. Chem. Commun., 2015, 51, 10150-10153.

(19) Wen Zhang, Xin Wang, Ping Li,* Fang Huang, Hui Wang, Wei Zhang and Bo Tang*. Elucidating the relationship between superoxide anion levels and lifespan using an enhanced two-photon fluorescence imaging probe. Chem. Commun., 2015, 51, 9710-9713.

2014

(18) Wei Zhang, Wei Liu, Ping Li,* Haibin Xiao, Hui Wang, and Bo Tang*. A Fluorescence Nanosensor for Glycoproteins with Activity Based on the Molecularly Imprinted Spatial Structureof the Target and Boronate Affinity. Angew. Chem. Int. Ed., 2014, 53, 12489-12493.

(17) Ping Li, Shan Zhang, Nannan Fan, Haibin Xiao, Wen Zhang, Wei Zhang, Hui Wang, and Bo Tang*. Quantitative Fluorescence Ratio Imaging of Intralysosomal Chloride Ions with Single Excitation/Dual Maximum Emission. Chem. Eur. J., 2014, 20, 11760-11767.

(16) Wen Gao, Wenhua Cao, Huaibin Zhang, Ping Li, Kehua Xu and Bo Tang*. Targeting lysosomal membrane permeabilization to induce and image apoptosis in cancer cells by multifunctional Au-ZnO hybrid nanoparticles. Chem. Commun., 2014, 50, 8117-8120.

(15) Ping Li, Haibin Xiao, Yinfang Cheng, Wen Zhang, Fang Huang, Wei Zhang, Hui Wang and Bo Tang*. A near-infrared-emitting fluorescent probe for monitoring mitochondrial pH. Chem. Commun., 2014, 50, 7184-7187.

2013

(14) Wen Zhang,† Ping Li,† Fan Yang, Xiufen Hu, Chuanzhi Sun, Wei Zhang, Dezhan Chen, and Bo Tang*. Dynamic and Reversible Fluorescence Imaging of Superoxide Anion Fluctuations in Live Cells and in Vivo. J. Am. Chem. Soc., 2013, 135, 14956-14959.

(13) Ping Li, Wen Zhang, Kexiang Li, Xiao Liu, Haibin Xiao, Wei Zhang, and Bo Tang*. Mitochondria-Targeted Reaction-Based Two-Photon Fluorescent Probe for Imaging of Superoxide Anion in Live Cells and in Vivo. Anal. Chem., 2013, 85, 9877-9881.

(12) Xi-Feng Shi,Na Li, Ke Zhao, Guan-Wei Cui, Ying-Qiang Zhao, Ming-Yue Ma, Ke-Hua Xu, Ping Li, Yu-Bin Dong*, Bo Tang*. A dye-sensitized FeOOH-CNT photocatalyst with threeelectron transfer channels regulated by hydrogen bonding. Appl. Catal. B. Environ., 2013, 136-137, 334-340.

2012

(11) Ping Li, TingXie, Nannan Fan, Kexiang Li and Bo Tang*. Ratiometric fluorescence imaging for distinguishing chloride concentration between normal and ischemic ventricular myocytes. Chem. Commun., 2012, 48, 2077-2079.

(10) Wen Gao, LifeiJi, Lu Li, Guanwei Cui, Kehua Xu, Ping Li, Bo Tang*. Bifunctional combined Au-Fe2O3 nanoparticles for induction of cancer cell-specific apoptosis and real-time imaging. Biomaterials, 2012, 33, 3710-3718.

2011

(9) Ping Li, Xia Duan, Zhenzhen Chen, Ying Liu, Ting Xie, Libo Fang, Xiaorui Li, Miao Yin and Bo Tang*. A near-infrared fluorescent probe for detecting copper (II) with high selectivity and sensitivity and its biological imaging applications. Chem.Commun., 2011, 47, 7755-7757.

(8) Kehua Xu, Lulu Wang, Mingming Qiang, Liyong Wang, Ping Li and Bo Tang*. A selective near-infrared fluorescent probe for singlet oxygen in living cells. Chem. Commun., 2011, 47, 7386-7388.

(7) Ping Li, Libo Fang, Hui Zhou, Wen Zhang, Xu Wang, Na Li, Hongbo Zhong, and Bo Tang*. A New Ratiometric Fluorescent Probe for Detection of Fe2+ with High Sensitivity and Its Intracellular Imaging Applications. Chem. Eur. J., 2011, 17,10520-10523.

2011年之前

(6) Ping Li, TingXie, Xia Duan, Fabiao Yu, Xu Wang and Bo Tang*. A New Highly Selective and Sensitive Assay for Fluorescence Imaging of OH in Living Cells: Effectively Avoiding the Interference of Peroxynitrite. Chem. Eur. J., 2010, 16, 1834-1840.

(5) Bo Tang*, Fabiao Yu, Ping Li, Lili Tong, Xia Duan, Ting Xie, and Xu Wang. A Near-Infrared Neutral pH Fluorescent Probe for Monitoring Minor pH Changes: Imaging in LivingHepG2 and HL-7702 Cells. J. Am. Chem. Soc., 2009, 131, 3016-3023.

(4) Fabiao Yu, Wenshen Zhang, Ping Li, Yanlong Xing, Lili Tong, Jianping Ma and Bo Tang*. Cu2+-selective naked-eye and fluorescent probe: its crystal structure and application in bioimaging. Analyst, 2009, 134, 1826-1833.

(3) Ping Li, Bo Tang*, Yanlong Xing, Puming Li, Guiwen Yang and Liang Zhang. A near-infrared fluorescent probe for lipid hydroperoxides in living cells. Analyst, 2008, 133, 1409-1415.

(2) Bo Tang*, Yanlong Xing, Ping Li, Ning Zhang, Fabiao Yu, and Guiwen Yang. A Rhodamine-Based Fluorescent Probe Containing a Se-N Bond for Detecting Thiols and Its Application in Living Cells. J. Am. Chem. Soc., 2007, 129, 11666-11667.

(1) Kehua Xu, Bo Tang*, Hui Huang, Guiwen Yang, Zhenzhen Chen, Ping Li and Liguo An. Strong Red Fluorescent Probes Suitable for Detecting Hydrogen Peroxide Generated by Mice Peritoneal Macrophages. Chem. Commun., 2005, 5974-5976.


授权发明专利

(1) 唐波,李平,肖海滨,张雯,具有大斯托克斯位移的近红外荧光染料及合成方法与应用,2014.10.31,中国,ZL201410606444.X

(2) 唐波,李平,肖海滨,一种对环境极性敏感的近红外荧光探针及其合成方法和应用,2015.4.30,中国,ZL201510218987.9

(3) 唐波,李平,张彦笛,王昕,张雯,一种特异性双光子成像荧光探针及制备方法与应用,2019.07.23,中国,CN 110041296 A

(4) 唐波,李平,吴丽杰,范楠楠,近红外荧光化合物与制备方法及其检测亚铁离子的应用,2019.12.13,中国,CN 110563702 A

(5) 唐波,李平,白晓艺,王昕,张雯,一种检测锌离子和pH的荧光探针、其制备方法与应用,2020.09.29,中国,CN 110698493 В

(6) 唐波,丁琪,李平,王昕,一种双色荧光探针及其合成方法与应用,2020.11.20,中国, CN 110963995 В

(7) 唐波,王慧,李平,杨玉云,花菁类化合物及制备方法与在检测高尔基体pH中的应用,2020.11.20,中国,CN 110551056 B

(8) 唐波,丁琪,李平,王昕,张彦笛,一种检测抑郁症小鼠脑内Cys的近红外荧光探针及其合成方法与应用,2021.02.23,中国,CN 111057047 B

(9) 唐波,丁琪,李平,王昕,一种检测过氧化物酶体中超氧阴离子自由基的荧光探针及其应用,2021.08.17,中国,CN 111100184 B

(10) 唐波,李平,苏迪,张雯,王昕,一种双光子荧光碳点材料及合成方法与应用,2021.11.09,中国,CN 110041924 B

(11) 唐波,李平,白晓艺,王昕,张雯,郭笑萌,一种定位高尔基体近红外荧光探针及其合成方法与应用,2022.02.08,中国,CN 110093153 B