【2024年】：

(39) Yuting Gui, Yaokun Zhao, Xingchi Li, Taoyuan Liang, Shuangliang Zhao,* Zhuan Zhang.* Catalyst-Controlled Regiodivergent C–H Alkynylation of 2-Pyridylthiophenes. Adv. Synth. Catal. 2024, Accepted. DOI: 10.1002/adsc.202400856. 

(38) Fang Huang,⁺ Xiangyu Chen,⁺ Huanhuan Sun, Qingduo Zeng, Junjie Ma, Dong Wei, Jinliang Zhu, Zhengjun Chen, Taoyuan Liang, Xucai Yin, Xijun Liu, Jing Xu,* and Huibing He.* Atmosphere Induces Tunable Oxygen Vacancies to Stabilize Single-Atom Copper in Ceria for Robust Electrocatalytic CO2 Reduction to CH4. Angew. Chem. Int. Ed. 2024, e202415642. DOI: 10.1002/anie.202415642.

(37) Maoyi Dai, Meilan Xu, Xiaoting Gu, Pengyan Zhang, Yukun Xie, Jin Zhuge, Xinting Liang, Runmin Liao, Zongwu Wei, Zhuan Zhang, and Taoyuan Liang,* Iron-catalyzed C−H arylphosphorylation of quinoxalines. Org. Lett. 2024, 26, 7672–7677. DOI: 10.1021/acs.orglett.4c02791.

(36) Yaokun Zhao, Xingchi Li, Pengfei Zhou, Xing Han, Chenjie Zhang, Taoyuan Liang, Shuangliang Zhao,* Zhuan Zhang,* Rh-Catalyzed C–H Alkynylation of Indole Derivatives with Silver(I)-Controlled Regiodivergence. Org. Lett. 2024, 26, 7285–7290. DOI: 10.1021/acs.orglett.4c02151.

(35) Pengfei Zhou, Cheng Wang, Guibin Wan,. Weining Zheng, Zongwu Wei, Taoyuan Liang, Jun Jiang,* Zhuan Zhang,* Regiodivergent Metal-Catalyzed Oxidative Alkynylation of 2-Arylthiazoles with Terminal Alkynes under Air Conditions. J. Org. Chem. 2024, 89, 10953–10964. DOI: 10.1021/acs.joc.4c01381.

(34) Xiaoting Gu, Maoyi Dai, Xirui Qing, Yifeng Liu, Zhuan Zhang, Zongwu Wei,* Taoyuan Liang,* Iron-Catalyzed Friedel-Crafts-Type 3,5-Diacylation of Indoles. J. Org. Chem. 2024, 89, 10272–10282. DOI: 10.1021/acs.joc.4c01157.

(33) Pengfei Zhou,‡ Xinyao Liang,‡ Zekun Xu, Honggu Chen, Zongwu Wei, Taoyuan Liang, Jun Jiang* and  Zhuan Zhang* Regiodivergent C–H alkynylation of 2-arylthiazoles switched by RuII and PdII catalysis.  Chem. Commun., 2024, 60, 6679−6682. DOI: 10.1039/D4CC02254H.

(32) Yingying Zhang, Xiaoxiang Zhang, Junqiu Liao, Zongwu Wei, Zhuan Zhang, Taoyuan Liang* Organoselenium-catalyzed C2,3-diarylation of N−H indoles. J. Org. Chem. 2024, 89, 7216–7224. DOI: 10.1021/acs.joc.4c00622.

(31) Yifeng Liu, Xiaoting Gu, Xiaoxiang Zhang, Meilan Xu, Zhuan Zhang and Taoyuan Liang* Iodine–Mediated Oxidative Triple Functionalization of Indolines with Azoles and Diazonium Salts. Chem. Commun., 2024,  60, 4613–4616. DOI: 10.1039/D4CC00856A.

(30) Zhuan Zhang, Taoyuan Liang. Green Solvents in Organic Synthesis [BOOK] (Pages: 199-236). WILEY-VCH GmbH, Weinheim, Germany. 2024. Print ISBN: 9783527352005, Online ISBN: 9783527841943, DOI: 10.1002/9783527841943.

(29) Xiaoxiang Zhang, Xiaoting Gu, Yingying Zhang, Junqiu Liao, Meilan Xu, Zhuan Zhang and Taoyuan Liang* Solvent-Controlled Switchable Multicomponent Tandem Oxidative Triple Functionalization of Indolines. Org. Chem. Front., 2024, 11, 1933–1940. DOI: 10.1039/D4QO00030G. (Highlighted by Frontiers Journals, https://mp.weixin.qq.com/s/DHSfhqC-biIncGQCbS7EMQ)

(28) Xiaoxiang Zhang, Chenrui Liu, Wanxing Wei, Zhuan Zhang and Taoyuan Liang* Iodine-Dependent Oxidative Regioselective Aminochalcogenation of Indolines. Chem. Commun., 2024, 60, 1152–1155. DOI: 10.1039/D3CC05999E.

(27) Xiaoxiang Zhang, Chenrui Liu, Wenwei Pang, Xiaoting Gu, Wanxing Wei, Zhuan Zhang, Haiyan Chen and Taoyuan Liang,* Directing-group-free Strategy for the Iodine-mediated Regioselective Dichalcogenation of Indolines: Understanding the Full Catalytic Cycles. Org. Chem. Front. 2024, 11, 871–884. DOI: 10.1039/D3QO01492D.

【2023年】：

(26) Xiaoxiang Zhang,‡ Chenrui Liu,‡ Yingying Zhang, Fang Shen, Wanxing Wei, Zhuan Zhang and Taoyuan Liang* Organo-catalyzed C2,3−H Aminochalcogenation of Indoles with Secondary (Aliphatic) Amines. Org. Chem. Front. 2023, 10, 5886–5894. DOI: 10.1039/D3QO01457F.  (Highlighted by Frontiers Journals，https://mp.weixin.qq.com/s?__biz=MzI3NTk3Nzk3NQ==&mid=2247518481&idx=2&sn=fda0981ba37280b874ff4cb9ef1df5fa&chksm=eb7e4a89dc09c39ff4e6f24a42f4e66b417ddd4aa99ea7fdd10a15609b07cd42d72f1fc1df68&mpshare=1&scene=2&srcid=11077CUGtm8yMBkqPOQ7ns8J&sharer_shareinfo=9c26ac4eba4a8713c10c22b76a311295&sharer_shareinfo_first=dd6c59cf3452003e6443482cab5a8c9e#rd.)

(25) Maoyi Dai, Yingying Zhang, Xiaoxiang Zhang, Ruiyi Wang, Wanxing Wei, Zhuan Zhang, Taoyuan Liang* Iodine-mediated C2,3−H aminoheteroarylation of indoles. J. Org. Chem. 2023, 88, 15106–15117. DOI: 10.1021/acs.joc.3c01591.

(24) Xuecong Huang, Pengfei Zhou, Xingdong Yang, Ruiyi Wang, Guan Huang, Taoyuan Liang, Zhuan Zhang* Catalyst-Controlled Divergent C3/C5 Site-Selective C−H Arylation of 2-Pyridylthiophenes. Adv. Synth. Catal. 2023, 365, 3674–3679. DOI: 10.1002/adsc.202300724. 

(23) Wenhua Yu,‡ Yingying Zhang,‡ Xiaoxiang Zhang, Xiaoting Gu, Xirui Qing, Wanxing Wei, Zhuan Zhang, Guanghua Li,* Taoyuan Liang* Synthesis of 2,3-Diaminoindoles via a Copper-iodine Co-catalytic Strategy. Chin. J. Chem. 2023, 41, 3567–3572. DOI: 10.1002/cjoc.202300470. (Highlighted by Chin J Chem, https://mp.weixin.qq.com/s/QKYHvkZWAj7DQ9IZks3-iA; Highlighted by CBG, https://mp.weixin.qq.com/s/mvnzakwZ-QmKEvllqIO6tw.)

(22) Fengqi Yang, Pengfei Zhou, Zeng Huang, Junqiu Liao, Guan Huang, Taoyuan Liang, and Zhuan Zhang* Ruthenium(II)-Catalyzed Remote C–H Sulfonylation of 2-Pyridones. Org. Lett. 2023, 25, 5779–5783. DOI: 10.1021/acs.orglett.3c02004.

(21) Qiang Zhang,‡   Pengfei Zhou,‡   Yaokun Zhao,   Yeran Liu,   Taoyuan Liang,  Jun Jiang*  and  Zhuan Zhang* Catalyst-controlled regiodivergent C–H bond alkenylation of 2-pyridylthiophenes. Chem. Commun., 2023, 59, 8842–8845. DOI: 10.1039/D3CC02411C.

(20) Tianxiang Chen,§ Wenhua Yu,§ Ching Kit Tommy Wun, Tai-Sing Wu, Mingzi Sun,Sarah Day, Zehao Li, Bo Yuan, Yong Wang, Mingjie Li, Zi Wang, Yung-Kang Peng,Wing-yiu Yu, Kwok-yin Wong, Bolong Huang,* Taoyuan Liang,* Tsz Woon Benedict Lo,* Cu-Co dual-atom catalysts supported on hierarchical USY zeolites for the efficient cross-dehydrogenative C(sp2)–N coupling reaction. J. Am. Chem. Soc. 2023. 145, 8464–8473. DOI:10.1021/jacs.3c00114. (Highlighted by X-MOL, https://www.x-mol.com/news/851296;  Highlighted by CBG, https://mp.weixin.qq.com/s/gv6sHR4h8RT9-iscw-UFLg.)

(19) Xiaoting Gu.§ Xiaoxiang Zhang,§ Wenhua Yu, Ke Sun, Wanxing Wei, Zhuan Zhang, and Taoyuan Liang,* Multicomponent Tandem Triple Functionalization of Indoles via a Directing-group-free Strategy. Adv. Synth. Catal. 2023, 365, 990–996. DOI: 10.1002/adsc.202300208. (Highlighted by CBG, https://mp.weixin.qq.com/s/BMxNZCw6hcRiVUF30Q0dlw.) 

(18) Qiang Zhang, Xuecong Huang, Yuting Gui, Youyuan He, Siyang Liao, Guan Huang, Taoyuan Liang, and Zhuan Zhang,* Unlocking Regiodivergence in PdII- and RhIII-Mediated Site-Selective C–H Bond Alkynylation of Imidazopyridines. Org. Lett. 2023, 25, 1447–1452. DOI: 10.1021/acs.orglett.3c00178.

(17) Zhengcheng Liang, Yongqing Tan, Yunhou Huang, Taoyuan Liang,* Wanxing Wei,* Mian Wang,* Kaichuang Shi, Design and Synthesis of (3-Phenylisoxazol-5-yl)methanimine Derivatives as Hepatitis B Virus Inhibitors. Chem. Biodivers. 2023, 20, e202201247. DOI: 10.1002/cbdv.202201247.

(16) Zhengcheng Liang, Yunhou Huang, Huihua Li, Xiaoxiang Zhang, Kaichuang Shi, Ning Zang, Mian Wang,* Taoyuan Liang,* Wanxing Wei,* Synthesis and evaluation of 3-phenylisoxazoline derivatives as non-nucleoside hepatitis B virus inhibitors. Tetrahedron 2023, 130, 133177. DOI: 10.1016/j.tet.2022.133177.

(15) Aonan Ren, Wanxing Wei,* Zhengcheng Liang, Min Zhou, Taoyuan Liang, Ning Zang. Synthesis and bioactive evaluation of N-((1-methyl-1H-indol-3-yl)methyl)-N-(3,4,5-trimethoxyphenyl)acetamide derivatives as agents for inhibiting tubulin polymerization. RSC Med. Chem., 2023, 14, 113–121. DOI: 10.1039/D2MD00340F.

(14) Ziyue Xie, Zhengcheng Liang, Yunhou Huang, Kaichuang Shi, Ning Zang, Mian Wang,* Taoyuan Liang*.Wanxing Wei,* Discovery and biological evaluation of 2-((3-phenylisoxazol-5-yl) methoxy) benzamide derivatives as potent nucleocapsid inhibitors. J. Mol. Struct. 2023, 1272, 134103. DOI: 10.1016/j.molstruc.2022.134103.

【2022年】：

(13) Yuanhui Lu, Xiaoxiang Zhang, Xiaoyu Xiao, Ninghua Huang, Yadong Dou, Chenrui Liu, Wanxing Wei, Zhuan Zhang, and Taoyuan Liang*. Copper-mediated intermolecular C−H aminohalogenation of indoles at room temperature. Asian J. Org. Chem. 2022, 11, e202200457.  DOI: 10.1002/ajoc.202200457. (Highlighted by WileyChem, https://mp.weixin.qq.com/s/Iq7PkVe5_I_dRl3Iahvu2g.)

(12) Wenhua Yu, Xiaoxiang Zhang, Chenrui Liu, Yingying Zhang, Xiaoting Gu, Jiahao Liao, Zhuan  Zhang, Wanxing Wei,* Guanghua Li,* and Taoyuan Liang*. Intermolecular C−H aminocyanation of indoles via copper-iodine co-catalyzed tandem C−N/C−C bond formation. J. Org. Chem. 2022, 87, 12424–12433.  DOI: 10.1021/acs.joc.2c01703. (Highlighted by OPR&D, https://doi.org/10.1021/acs.oprd.3c00022.)

(11) Yingying Zhang, Yating Huang, Kewei Yu, Xiaoxiang Zhang, Wenhua Yu, Jiale Tang, Yiran Tian, Wanxing Wei, Zhuan  Zhang,* and Taoyuan Liang*. Iron-iodine co-catalysis towards tandem C−N/C−C bond formation: one-pot regioselective synthesis of 2-amino-3-alkylindoles. Org. Chem. Front. 2022, 9, 6165–6171. DOI: 10.1039/D2QO01329K. (Highlighted by Frontiers Journals, https://mp.weixin.qq.com/s/KIK3R-eoV10xuicSRl1sNA.)

(10) Yuanhui Lu,‡ Tianxiang Chen,‡ Xiaoyu Xiao, Ninghua Huang, Yadong Dou, Wanxing Wei, Zhuan Zhang, Benedict Tsz Woon Lo* and Taoyuan Liang*. Copper dual-atom catalyst mediated C3−H amination of indoles at room temperature. Catal. Sci. Technol., 2022, 12, 5390–5396. DOI: 10.1039/D2CY01126C. 

(9) Xiaoxiang Zhang, Wenhua Yu, Yiyu Nie, Yingying Zhang, Xiaoting Gu, Wanxing Wei, Zhuan Zhang,and Taoyuan Liang*. Copper-iodine Co-catalyzed C−H Aminoalkenylation of Indoles via Temperature-Controlled Selectivity Switch: Facile Synthesis of 2-Azolyl-3-alkenylindoles. Org. Chem. Front. 2022, 9, 3794–3799. DOI: 10.1039/D2QO00627H. (Highlighted by Frontiers Journals, https://mp.weixin.qq.com/s/8i5m1WmL9o4SBNs50hEI4w.）

(8) Yunhou Huang, Na Liu, Qiuyue Ning, Min Zhou, Ning Zang*, Taoyuan Liang*, Wanxing Wei*. Design, synthesis, and biological evaluation of novel (E)-1-arylethan-1-one O-((3-arylisoxazol-5-yl) methyl) oxime derivatives as potent non-nucleoside HBV inhibitors. J. Mol. Struct. 2022, 1260, 132789. DOI: 10.1016/j.molstruc.2022.132789.

【2021年】：

(7) Taoyuan Liang, He Zhao*, Lingzhen Gong, Huanfeng Jiang and Min Zhang*. Synthesis of Functionalized Benzimidazoles via Oxidative Tandem Quartic C–H Aminations and Cleavage of C–N and C–C bonds. Chem. Commun. 2021, 57, 12976–12979. DOI: 10.1039/D1CC05521F.

(6) Xiaoxiang Zhang, Yingying Zhang, Xiaoting Gu, Zhuan Zhang, Wanxing Wei* and Taoyuan Liang*. Synthesis of 3-Halogenated 2,3′-Biindoles by a Copper-mediated 2,3-Difunctionalization of Indoles. Org. Biomol. Chem. 2021, 19, 10403–10407. DOI: 10.1039/D1OB02024B.

【-2020年】

(5) Taoyuan Liang, Lingzhen Gong, He Zhao, Huanfeng Jiang, Min Zhang*. Straightforward Access to Novel indolo[2,3-b]indoles via Aerobic Copper-catalyzed [3 + 2] Annulation of Diarylamines and Indoles. Chem. Commun. 2020, 56, 2807–2810. DOI: 10.1039/D0CC00178C.

(4) Taoyuan Liang, He Zhao, Lingzhen Gong, Huanfeng Jiang, Min Zhang*. Direct Access to Functionalized Indoles via Single Electron Oxidation Induced Coupling of Diarylamines with 1,3-Dicarbonyl Compounds. Org. Lett. 2019, 21, 6736–6740. DOI: 10.1021/acs.orglett.9b02349.

(3) Taoyuan Liang, He Zhao, Lingzhen Gong, Huanfeng Jiang, Min Zhang*. Synthesis of Multisubstituted Benzimidazolones via Copper-catalyzed Oxidative Tandem C–H Aminations and Alkyl Deconstructive Carbofunctionalization. iScience 2019, 15, 127–135. DOI: 10.1016/j.isci.2019.04.019.

(2) Taoyuan Liang, Zhenda Tan, He Zhao, Xiuwen Chen, Huanfeng Jiang, Min Zhang*. Aerobic Copper-Catalyzed Synthesis of Benzimidazoles from Diaryl- and Alkylamines via Tandem Triple C–H Aminations. ACS Catal. 2018, 8, 2242-2246. DOI: 10.1021/acscatal.8b00082.

(1) Jinpeng Chen, Taoyuan Liang, He Zhao, Chuyuan Lin, Lu Chen, Min Zhang*. Silver-mediated Three-Component Cycloaddition Reaction for Direct Synthesis of 1-N-vinyl-substituted 1,2,3-Triazoles. Org. Biomol. Chem. 2019, 17, 4843–484. DOI: 10.1039/C9OB00686A.

【发明专利】：

1. 张珉，梁桃源，一种一步合成5-二芳氨基苯并咪唑衍生物的方法，已授权，ZL201710256605.0;

2. 张珉，梁桃源，一种一步合成5-二芳氨基苯并咪唑酮衍生物的方法，已授权，ZL201711225340.4;

3. 张珉，梁桃源，一种一步合成2-氨基吲哚并[2,3-b]吲哚衍生物的方法，CN202010133018.4;

4. 梁桃源，张晓翔，韦万兴，2-烷基对苯二醌类化合物的合成方法，已授权，ZL202110415372.0;

5. 梁桃源，卢远辉，肖晓宇，黄宁华，豆雅东，一种2-氨基-3-卤代吲哚衍生物的合成方法，CN202210194273.9;

6. 梁桃源，余珂微，张莹莹，唐嘉乐，田一然，一种2-唑基-3-烷基吲哚衍生物的合成方法，CN202211183607.9.；

7. 梁桃源，肖晓宇，张晓翔，黄宁华，豆雅东，一种2-氨基-5-硫基吲哚衍生物的合成方法，CN202310193470.3.