# Co-first authors, * Corresponding authors

1. Qingyuan Deng^#, Ao Hua^#, Shiyou Li, Zhijie Zhang, Xiang Chen, Qiang Wang, Xing Wang, Zhiqin Chu, Xiangliang Yang^*, Zifu Li*. Hyperbaric oxygen regulates tumor pH to boost copper-doped hydroxyethyl starch conjugate nanoparticles against cancer stem cells. Exploration, 2024, EXP.20240080

2. Zitao Fan^#, Xing Wang^#, Xiangliang Yang, Zifu Li*. Boosting oxidative stress with hydroxyethyl starch smart nanomedicines to eliminate cancer stem cells. Accounts of Materials Research, 2024, https://pubs.acs.org/doi/10.1021/accountsmr.4c00240

3. Xiang Chen^#, Zhengtao Yong^#, Yuxuan Xiong^#, Hai Yang^#, Chen Xu, Xing Wang, Qingyuan Deng, Jiayuan Li, Xiangliang Yang, Zifu Li*. Hydroxyethyl starch conjugates co-assembled nanoparticles promote photodynamic therapy and antitumor immunity by inhibiting antioxidant systems. Asian Journal of Pharmaceutical Sciences, 2024, 100950, https://www.sciencedirect.com/science/article/pii/S1818087624000679

4. Chen Xiao^#, Xing Wang^#, Shiyou Li, Zhijie Zhang, Jiayuan Li, Qingyuan Deng, Xiang Chen, Xiangliang Yang*, Zifu Li*. A cuproptosis-based nanomedicine suppresses triple negative breast cancers by regulating tumor microenvironment and eliminating cancer stem cells. Biomaterials, 2024, 122763

5. Yuxuan Xiong^#, Zhengtao Yong^#, Qingfu Zhao, Ao Hua, Xing Wang, Xiang Chen, Xiangliang Yang, Zifu Li^*. Hydroxyethyl starch-based self-reinforced nanomedicine inhibits both glutathione and thioredoxin antioxidant pathways to boost reactive oxygen species-powered immunotherapy. Biomaterials, 2024, 122673

6. Qiang Wang^#, Shiyou Li^#, Chen Xu^#, Xing Wang, Tian Yang, Chong Wang, Yuxuan Xiong, Zhijie Zhang, Xiangliang Yang, Zifu Li^*. Glutaminolysis inhibition boosts photodynamic therapy to eliminate cancer stem cells. Biomaterials, 2024, 306, 122497

7. Zheng Li^#, Yabo Zhu^#, Zhijie Zhang, Huimin Wang, Chong Wang, Chen Xu, Shiyou Li, Shuya Zhang, Xiangliang Yang, Zifu Li^*. Softness-aided mild hyperthermia boosts stiff nanomedicine by regulating tumor mechanics. Advanced Science, 2024, 2306730

8. Chen Xiao^#, Jiayuan Li^#, Ao Hua, Xing Wang, Shiyou Li, Zheng Li, Chen Xu, Zhijie Zhang, Xiangliang Yang^*, Zifu Li^*. Hyperbaric oxygen boosts antitumor efficacy of copper-diethyldithiocarbamate nanoparticles against pancreatic ductal adenocarcinoma by regulating cancer stem cell metabolism. Research, 2024, 10.34133/research.0335

9. Qingyuan Deng, Xiangliang Yang, Zifu Li^*. Hyperbaric oxygen: a multifaceted approach in cancer therapy. Medical Gas Research, 2024, (Invited Perspective)

10. Zheng Li, Xiangliang Yang, Zifu Li^*. Tumor mechanics meets nanomedicine mechanical properties. Chemistry of Materials, 2024, 36, 3, 1041-1053, (Invited Perspective, Journal Cover)

11. Yuxuan Xiong, Zhengtao Yong, Shiyou Li, Qiang Wang, Xiang Chen, Zhijie Zhang, Qingfu Zhao, Qingyuan Deng, Xiangliang Yang, Zifu Li^*. Self-reliant Nanomedicine with Long-lasting Glutathione Depletion Ability Disrupts Adaptive Redox Homeostasis and Suppresses Cancer Stem Cells. Advanced Functional Materials, 2023, 2310158

12. Qiang Wang, Tian Yang, Shiyou Li, Chen Xu, Chong Wang, Yuxuan Xiong, Xing Wang, Jiangling Wan, Xiangliang Yang^* and Zifu Li^*. Unimolecular self-assembled hemicyanine-oleic acid conjugate acts as a novel succinate dehydrogenase inhibitor to amplify photodynamic therapy and eliminate cancer stem cells. Research, 2023, https://spj.science.org/doi/10.34133/research.0223

13. Qingfu Zhao^#, Jitang Chen^#, Zhijie Zhang, Chen Xiao, Haowen Zeng, Chen Xu, Xiangliang Yang, Zifu Li^*. Modulating tumor mechanics with nanomedicine for cancer therapy. Biomaterials Science, 2023, 11, 4471-4489, (Emerging Investigator, Invited review)

14. Yuxuan Xiong^#, Zhengtao Yong^#, Chen Xu^#, Qingyuan Deng, Qiang Wang, Shiyou Li, Chong Wang, Zhijie Zhang, Xiangliang Yang^*, Zifu Li^*. Hyperbaric oxygen activates enzyme‐driven cascade reactions for cooperative cancer therapy and cancer stem cells elimination. Advanced Science, 2023, 2301278

15. Qiang Wang^#, Shiyou Li^#, Chen Xu, Ao Hua, Chong Wang, Yuxuan Xiong, Qingyuan Deng, Xiang Chen, Tian Yang, Jiangling Wan, Ze-yang Ding, Bi-xiang Zhang, Xiangliang Yang, Zifu Li^*. A novel lonidamine derivative targeting mitochondria to eliminate cancer stem cells by blocking glutamine metabolism. Pharmacological Research, 2023, 190, 106740

16. Zheng Li, Yabo Zhu, Haowen Zeng, Chong Wang, Chen Xu, Qiang Wang, Huimin Wang, Shiyou Li, Jitang Chen, Chen Xiao, Xiangliang Yang, Zifu Li*. Mechano-boosting nanomedicine antitumour efficacy by blocking the reticuloendothelial system with stiff nanogels. Nature Communications, 2023, 14, 1437

17. Yuxuan Xiong^#, Wei Wang^#, Qingyuan Deng, Zhijie Zhang, Qiang Wang, Zhengtao Yong, Chaoyang Sun*, Xiangliang Yang, Zifu Li*. Mild photothermal therapy boosts nanomedicine antitumor efficacy by disrupting DNA damage repair pathways and modulating tumor mechanics. Nano Today, 2023, 101767

18. Wei Wang^#, Yuxuan Xiong^#, Xingyuan Hu, Funian Lu, Tianyu Qin, Li Zhang, Ensong Guo, Bin Yang, Yu Fu, Dianxing Hu, JunPeng Fan, Xu Qin, Chen Liu, RouRou Xiao, Gang Chen, Zifu Li*, Chaoyang Sun*. Codelivery of adavosertib and olaparib by tumor-targeting nanoparticles for augmented efficacy and reduced toxicity. Acta Biomaterialia, 2023, 157, 428-441

19. Chen Xu, Shiyou Li, Jitang Chen, Huimin Wang, Zheng Li, Qingyuan Deng, Jiayuan Li, Xing Wang, Yuxuan Xiong, Zhijie Zhang, Xiangliang Yang, Zifu Li*. Doxorubicin and erastin co-loaded hydroxyethyl starch-polycaprolactone nanoparticles for synergistic cancer therapy. Journal of Controlled Release, 2023, 356, 256-271

20. Chen Xiao^#, Jiayuan Li^#, Xing Wang^#, Shiyou Li, Chen Xu, Zhijie Zhang, Ao Hua, Ze-yang Ding, Bi-xiang Zhang, Xiangliang Yang, Zifu Li^*. Hydroxyethyl starch stabilized copper-diethyldithiocarbamate nanocrystals for cancer therapy. Journal of Controlled Release, 2023, 356, 288-305

21. Chong Wang^#, Qiang Wang^#, Huimin Wang^#, Zheng Li, Jitang Chen, Zhijie Zhang, Haowen Zeng, Ximiao Yu, Xiaoquan Yang, Xiangliang Yang, Zifu Li*. Hydroxyethyl starch-folic acid conjugates stabilized theranostic nanoparticles for cancer therapy. Journal of Controlled Release, 2023, 353, 391-410

22. Chong Wang^#, Huimin Wang^#, Hai Yang^#, Chen Xu, Qiang Wang, Zheng Li, Zhijie Zhang, Jiankun Guan, Ximiao Yu, Xiaoquan Yang, Xiangliang Yang, Zifu Li*. Targeting cancer-associated fibroblasts with hydroxyethyl starch nanomedicine boosts cancer therapy. Nano Research, 2023 https://doi.org/10.1007/s12274-023-5394-7

23. Zhijie Zhang^#, Zibing Wang^#, Yuxuan Xiong^#, Chong Wang, Qingyuan Deng, Tian Yang, Qingqing Xu, Zhengtao Yong, Xiangliang Yang, Zifu Li*. A two-pronged strategy to alleviate tumor hypoxia and potentiate photodynamic therapy by mild hyperthermia. Biomaterials Science, 2023, 11, 108-118 (Back Cover)

24. Zhijie Zhang^#, Qingyuan Deng^#, Chen Xiao, Zifu Li*, Xiangliang Yang*. Rational design of nanotherapeutics based on five features principle for potent elimination of cancer stem cells. Accounts of Chemical Research, 2022, 55, 526-536, (Invited review)

25. Xiaoxian Wang^#, Ningbing Ye^#, Chen Xu^#, Chen Xiao^#, Zhijie Zhang^#, Qingyuan Deng, Shiyou Li, Jiayuan Li, Zifu Li*, Xiangliang Yang. Hyperbaric oxygen regulates tumor mechanics and augments Abraxane and gemcitabine antitumor effects against pancreatic ductal adenocarcinoma by inhibiting cancer-associated fibroblasts. Nano Today, 2022, 101458

26. Qiang Wang^#, Chong Wang^#, Shiyou Li^#, Yuxuan Xiong, Huimin Wang, Zheng Li, Jiangling Wan, Xiangliang Yang, Zifu Li*. Influence of Linkers within Stimuli-Responsive Prodrugs on Cancer Therapy: A Case of Five Doxorubicin Dimer-Based Nanoparticles. Chemistry of Materials, 2022, 34, 5, 2085-2097

27. Yuxuan Xiong^#, Zibing Wang^#, Qiang Wang, Qingyuan Deng, Jitang Chen, Jianshuang Wei, Xiaoquan Yang, Xiangliang Yang, Zifu Li*. Tumor-specific activatable biopolymer nanoparticles stabilized by hydroxyethyl starch prodrug for self-amplified cooperative cancer therapy. Theranostics, 2022, 12, 944-962

28. Hang Hu^#, Xin Liu^#, Jun Hong^#, Ningbing Ye, Chen Xiao, Jianhao Wang*, Zifu Li*, Defeng Xu*. Mesoporous polydopamine-based multifunctional nanoparticles for enhanced cancer phototherapy. Journal of Colloid and Interface Science, 2022, 612, 246-260

29. Jitang Chen, Zhijie Zhang, Nining Li, Haowen Zeng, Zheng Li, Chong Wang, Chen Xu, Qingyuan Deng, Qiang Wang, Xiangliang Yang, Zifu Li*. Precise fibrin decomposition and tumor mechanics modulation with hydroxyethyl starch-based smart nanomedicine for enhanced antitumor efficacy. J. Mater. Chem. B, 2022, 10, 8193-8210

30. Xin Liu^#, Ningbing Ye^#, Chen Xiao, Xiaoxian Wang, Shiyou Li, Yihan Deng, Xiaoquan Yang, Zifu Li*, Xiangliang Yang. Hyperbaric oxygen regulates tumor microenvironment and boosts commercialized nanomedicine delivery for potent eradication of cancer stem-like cells. Nano Today, 2021, 101248

31. Xin Liu^#, Ningbing Ye^#, Sha Liu^#, Jiankun Guan, Qingyuan Deng, Zhijie Zhang, Chen Xiao, Ze-yang Ding, Bi-xiang Zhang, Xiao-ping Chen, Zifu Li*, Xiangliang Yang. Hyperbaric Oxygen Boosts PD-1 Antibody Delivery and T Cell Infiltration for Augmented Immune Responses Against Solid Tumors. Advanced Science, 2021, 2100233

32. Jiankun Guan^#, Yuxin Wu^#, Xin Liu^#, Huimin Wang, Ningbing Ye, Zheng Li, Chen Xiao, Zhijie Zhang, Zifu Li*, Xiangliang Yang. A novel prodrug and its nanoformulation suppress cancer stem cells by inducing immunogenic cell death and inhibiting indoleamine 2, 3-dioxygenase. Biomaterials, 2021, 121180

33. Jiankun Guan^#, Yuxin Wu^#, Huimin Wang, Haowen Zeng, Zifu Li*, Xiangliang Yang. DiR loaded tumor targeting theranostic cisplatin-icodextrin prodrug nanoparticle for imaging guided chemo-photothermal cancer therapy. Nanoscale, 2021, 13, 19399-19411 (Back Cover, 2021 Nanoscale HOT Article Collection)

34. Jitang Chen^#, Si Li^#, Xin Liu, Sha Liu, Chen Xiao, Zhijie Zhang, Shiyou Li, Zifu Li*, Xiangliang Yang. Transforming growth factor-β blockade modulates tumor mechanical microenvironment for enhanced antitumor efficacy of photodynamic therapy. Nanoscale, 2021, 13, 9989-10001 (Inside Back Cover, 2021 Nanoscale HOT Article Collection)

35. Yuxuan Xiong^#, Chen Xiao^#, Zifu Li*, Xiangliang Yang. Engineering nanomedicine for glutathione depletion-augmented cancer therapy. Chemical Society Reviews, 2021, 50, 6013-6041 (Invited review)

36. Huimin Wang^#, Hang Hu^#, Hai Yang, Zifu Li*. Hydroxyethyl starch based smart nanomedicine. RSC Advances 2021,11, 3226-3240 (Invited review)

37. Jitang Chen^#, Ze-yang Ding^#, Si Li^#, Sha Liu^#, Chen Xiao, Zifu Li*, Bi-xiang Zhang*, Xiao-ping Chen, Xiangliang Yang*. Targeting transforming growth factor-β signaling for enhanced cancer chemotherapy. Theranostics, 2021, 11, 1345-1363 (Invited review)

38. Xiaoxian Wang, Si Li, Xin Liu, Xian Wu, Ningbing Ye, Xiangliang Yang, Zifu Li*. Boosting Nanomedicine Efficacy with Hyperbaric Oxygen Therapy. Bio-Nanomedicine for Cancer Therapy 2021 pp 77-95 (Invited review)

39. Qiang Wang, Jiankun Guan, Jiangling Wan, Zifu Li*. Disulfide based prodrugs for cancer therapy. RSC Advances 2020,10, 24397-24409 (Invited review)

40. Zheng Li^#, Chen Xiao^#, Tuying Yong^#, Zifu Li*, Lu Gan*, Xiangliang Yang*. Influence of nanomedicine mechanical properties on tumor targeting delivery. Chemical Society Reviews, 2020, 49, 2273-2290 (Inside Front Cover, Invited review)

41. Zhijie Zhang^#, Chen Xiao^#, Tuying Yong^#, Xiangliang Yang, Lu Gan*, Zifu Li*. Cellular microparticles for tumor targeting delivery: from bench to bedside. Chemical Communications, 2020, 56, 6171-6188 (Inside Back Cover, Invited review)

42. Zifu Li, Chunzhi Di, Suping Li*, Xiangliang Yang*, Guangjun Nie*. Smart Nanotherapeutic Targeting of Tumor Vasculature. Accounts of Chemical Research, 2019, 52, 2703-2712 (Invited review)

43. Yihui Li^#, Yuxin Wu^#, Jitang Chen^#, Jiangling Wan^#, Chen Xiao, Jiankun Guan, Xianlin Song, Shiyou Li, Mengmeng Zhang, Huangchen Cui, Tiantian Li, Xiaoquan Yang, Zifu Li*, Xiangliang Yang*. A Simple Glutathione-Responsive Turn-On Theranostic Nanoparticle for Dual-Modal Imaging and Chemo-Photothermal Combination Therapy. Nano Letters, 2019, 19, 5806-5817

44. Yuxuan Xiong, Zushun Xu*, Zifu Li*. Polydopamine-Based Nanocarriers for Photosensitizer Delivery. Frontiers in Chemistry 2019 (Invited review) https://doi.org/10.3389/fchem.2019.00471

45. Hang Hu^#, Jitang Chen^#, Hai Yang^#, Xuetao Huang, Honglian Wu, Yuxin Wu, Fenfang Li, Yunfei Yi, Chen Xiao, Yihui Li, Yuxiang Tang, Zifu Li*, Bixiang Zhang*, Xiangliang Yang*. Potentiating photodynamic therapy of ICG-loaded nanoparticles by depleting GSH with PEITC. Nanoscale 2019, 11, 6384-6393

46. Yuxiang Tang^#, Yihui Li^#, Si Li^#, Hang Hu, Yuxin Wu, Chen Xiao, Zhiqin Chu, Zifu Li*, Xiangliang Yang. Transformable nanotherapeutics enabled by ICG: towards enhanced tumor penetration under NIR light irradiation. Nanoscale 2019, 11, 6217-6227

47. Chen Xiao^#, Hang Hu^#, Hai Yang^#, Si Li, Hui Zhou, Jian Ruan, Yuting Zhu, Xiangliang Yang, Zifu Li*. Colloidal hydroxyethyl starch for tumor-targeted platinum delivery. Nanoscale Advances 2019, 1, 1002-1012

48. Xian Wu^#, Yanhong Zhu^#, Wei Huang, Jingqiu Li, Bixiang Zhang, Zifu Li*, Xiangliang Yang*. Hyperbaric Oxygen Potentiates Doxil Antitumor Efficacy by Promoting Tumor Penetration and Sensitizing Cancer Cells. Advanced Science, 2018, 5, 1700859

49. Qing Zhou^#, Yihui Li^#, Yanhong Zhu^#, Chan Yu, Haibo Jia, Binghao Bao, Hang Hu, Chen Xiao, Jianqi Zhang, Xiaofan Zeng, Ying Wan, Huibi Xu, Zifu Li*, Xiangliang Yang*. Co-delivery nanoparticle to overcome metastasis promoted by insufficient chemotherapy. Journal of Controlled Release, 2018, 275, 67-77

50. Yuxiang Tang^#, Yihui Li^#, Rong Xu^#, Si Li, Hang Hu, Chen Xiao, Honglian Wu, Lin Zhu, Jiaxiong Ming, Zhiqin Chu, Huibi Xu, Xiangliang Yang*, Zifu Li*. Self-assembly of folic acid dextran conjugates for cancer chemotherapy. Nanoscale 2018, 10, 17265-17274

51. Hang Hu^#, Jiangling Wan^#, Xuetao Huang^#, Yuxiang Tang, Chen Xiao, Huibi Xu, Xiangliang Yang*, Zifu Li*. iRGD-decorated reduction-responsive nanoclusters for targeted drug delivery. Nanoscale 2018 10, 10514–10527

52. Honglian Wu^#, Hang Hu^#, Jiangling Wan^#, Yaming Li, Yuxin Wu, Yuxiang Tang, Chen Xiao, Huibi Xu, Xiangliang Yang, Zifu Li*. Hydroxyethyl starch stabilized polydopamine nanoparticles for cancer chemotherapy. Chemical Engineering Journal, 2018 349, 129-145

53. Hang Hu^#, Chen Xiao^#, Honglian Wu, Yihui Li, Qing Zhou, Yuxiang Tang, Chan Yu, Xiangliang Yang*, Zifu Li*. Nanocolloidosomes with Selective Drug Release for Active Tumor-Targeted Imaging-Guided Photothermal/Chemo Combination Therapy. ACS Applied Materials & Interfaces, 2017, 9, 42225–42238

54. Yihui Li, Hang Hu, Qing Zhou, Yanxiao Ao, Chen Xiao, Jianglin Wan, Ying Wan, Huibi Xu, Zifu Li*, Xiangliang Yang*. α-Amylase- and Redox-Responsive Nanoparticles for Tumor-Targeted Drug Delivery. ACS Applied Materials & Interfaces, 2017, 9, 19215-19230

55. Hang Hu, Yihui Li, Qing Zhou, Yanxiao Ao, Chan Yu, Ying Wan, Huibi Xu, Zifu Li*, Xiangliang Yang*. Redox-Sensitive Hydroxyethyl Starch–Doxorubicin Conjugate for Tumor Targeted Drug Delivery. ACS Applied Materials & Interfaces, 2016, 8, 30833-30844