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成果及论文

²  Zhilin Li, Salli Antila, Harri Nurmi, Dmitri Chilov, Emilia A Korhonen, Shentong Fang, Sinem Karaman, Britta Engelhardt, Kari Alitalo*. Blockade of VEGFR3 signaling leads to functional impairment of dural lymphatic vessels without affecting autoimmune neuroinflammation. Science Immunology. 2023 Apr 14;8(82):eabq0375. IF: 24.8

²  Zhilin Li#, Emilia A Korhonen#, Arianna Merlini, Judith Strauss, Eleonoora Wihuri, Harri Nurmi, Salli Antila, Jennifer Paech, Urban Deutsch, Britta Engelhardt, Sudhakar Chintharlapalli, Gou Young Koh, Alexander Flügel, Kari Alitalo*. Angiopoietin-2 blockade ameliorates autoimmune neuroinflammation by inhibiting leukocyte recruitment into the CNS. Journal of Clinical Investigation. 2020 Apr 1;130(4):1977-1990. (#equal contribution) IF: 15.9

²  Zhilin Li, Mohd Moin Khan, Juha Kuja-Panula, Hongyun Wang, Yu Chen, Deyin Guo, Zhi Jane Chen, Riitta Lahesmaa, Heikki Rauvala, Li Tian*. AMIGO2 modulates T cell functions and its deficiency in mice ameliorates experimental autoimmune encephalomyelitis. Brain, Behavior, and Immunity. 2017 May:62:110-123. IF: 15.1

²  Olesya Okuneva#, Zhilin Li#, Inken Körber, Saara Tegelberg, Tarja Joensuu, Li Tian, Anna-Elina Lehesjoki*. Brain inflammation is accompanied by peripheral inflammation in Cstb -/- mice, a model for progressive myoclonus epilepsy. Journal of Neuroinflammation. 2016 Nov 28;13(1):298. (#equal contribution) IF: 9.3

²  Zhilin Li, Hong Wei, Sami Piirainen, Zuyue Chen, Eija Kalso, Antti Pertovaara, Li Tian*. Spinal versus brain microglial and macrophage activation traits determine the differential neuroinflammatory responses and analgesic effect of minocycline in chronic neuropathic pain. Brain, Behavior, and Immunity. 2016 Nov:58:107-117. IF: 15.1

²  Zhilin Li, Li Ma, Natalia Kulesskaya, Vootele Võikar, Li Tian*. Microglia are polarized to M1 type in high-anxiety inbred mice in response to lipopolysaccharide challenge. Brain, Behavior, and Immunity. 2014 May:38:237-48. IF: 15.1