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成果及论文

1. Xinming Li, Yanan Hou, Xianke Meng, Chunpo Ge, Huilong Ma, Jin Li and Jianguo Fang*. Selectiv Activation of a Prodrug by Thioredoxin Reductase Providing a Strategy to Target Cancer Cells. Angew. Chem Int. Ed.201857, 6141-6145. 

2. Xinming Li, Baoxin Zhang, Chaoxian Yan, Jin Li, Song Wang, Xiangxu Wei, Xiaoyan Jiang, Panpan Zhou Jianguo Fang*. A fast and specific fluorescent probe for thioredoxin reductase that works via disulphide bond cleavage. Nat. Commun., 2019, 10, 2745–2756.
3. Xinming Li, Yanan Hou, Jintao Zhao, Jin Li, Song Wang and Jianguo Fang*. Combination of chemotherap and oxidative stress to enhance cancer cell apoptosis. Chem. Sci., 2020, 11, 3215-3222. 
4. Xinming Li, Donglei Shi, Yihe Song, Yixiang Xu, Ying Gao, Wenjing Qiu, Xin Chen, Xiaokang Li, Yunyua Huang, Yanjun Feng, Baoli Li*, Yuan Guo*, and Jian Li*. Specific tracking of monoamine oxidase A in heart failure models by a far-red fluorescent probe with an ultra large Stokes shift. Chin. Chem. Lett., 202233, 1572-1576.

5. Yihe Song#, Xinming Li#, Donglei Shi#, Tianyue Sun, Wenwen Liu, Xiaokang Li, Sicong Qiao, Xin Chen, Yuan Guo* and Jian Li*. A senolysis-based theragnostic prodrug strategy towards chronic renal failure. Chem. Sci., 2022, 13, 11738.

6. Junmin Zhang, Xinming Li#, Zhengjia Zhao, Wenqing Cai, Jianguo Fang*. Thioredoxin Signaling Pathways in Cancer. Antioxid. Redox Signal., 2023, 38, 403-424.

7. Donglei Shi#, Linghao Hu#, Xinming Li#, Wenwen Liu, Ying Gao, Xiaokang Li, Bei Jiang, Conglong Xia, Yua Guo*, Jian Li*. Lysosomal polarity increases with aging as revealed by a lysosome-targetable near-infrare fluorescent probe. Sens. Actuators B Chem., 2020, 319, 128302. 
8. Yanan Hou, Shoujiao Peng, Zilong Song, Feifei Bai, Xinming Li*, Jianguo Fang*. Oat polypheno avenanthramide-2c confers protection from oxidative stress by regulating the Nrf2-ARE signaling pathway in PC12 cells. Arch. Biochem. Biophys., 2021, 706, 108857. 
9. Linghao Hu#, Donglei Shi#, Xinming Li#, Jin Zhu, Fei Mao, Xiaokang Li, Conglong Xia, Bei Jiang, Yuan Guo*, Jian Li*. Curcumin-based polarity fluorescent probes: Design strategy and biological applications. Dyes Pigm.2020, 177, 108320. 

10. Junmin Zhang , Xinming Li , Xiao Han , Ruijuan Liu , Jianguo Fang*. Targeting the Thioredoxin System for Cancer Therapy. Trends Pharmacol. Sci., 2017, 38, 794-808.

11. 一种抗癌前药分子及其制备方法与靶向化合物。房建国, 李新明。专利号 ZL201710824691.0(已授权)