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成果及论文

主要论著(近5年来已发表的与本项目有关的主要论著目录和获得学术奖励情况)


李玮:

1.Wei Li, Chun-hua Zhang,Yi-lin Hong JunLi, Yong-mei Hu, Cui-fen Zhao* Inhibitor of DNA-binding-1/inhibitor of differentiation-1 (ID-1) is implicated in various aspects of gastric cancer cell biology,Molecular Biology Reports 2012 ,39(3):3009-15 

2.Wei Li , Cui-fen Zhao*, Yi-lin Hong, Jun Li,Chun-hua Zhang, Hui Xiong,     Regulation of growth and sensitivity of gastric cancer cells to cisplatin by modulation of Inhibitor of DNA Binding or Differentiation Protein (ID) expression , Laboratory Medicine,2012, 43(5):189-196

3.Wei Li*, Ai-ping Song,Fang Zhao, Yong-mei Hu ,Hua Mu, A novel human TINP1 gene promotes cell proliferation by inhibition of p53 and p21 expression,oncology reports, 2013 ,30(4):1848-52

4.Wei Li ,Qing-yu Kong, Cui-fen Zhao*, Fang Zhao,Fu-hai Li,Xia Wang,Rong Wang,  Yong-mei Hu,Hua Mu, Adrenomedullin and adrenotensin regulate collagen synthesis and proliferation in pulmonary arterial smooth muscle cells,Brazilian journal of medical and biological research, 2013 ,46(12):1047-1055

5.Li W, Cai Z, Liu M, Zhao C*, Li D, Lv C, Wang Y, Xu TUrotensin II   contributesto collagen synthesis and up-regulates Egr-1 expression in cultured pulmonaryarterial smooth muscle cells through the ERK1/2 pathway,Biochem Biophys Res Commun,2015, 467(4):1076-82.

6. Li W, Guo A, Wang L, Kong Q, Wang R, Han L, Zhao C, Expression of peptidefragments from proADM and involvement of mitogen-activated protein kinasesignaling pathways in pulmonary remodeling induced by high pulmonary blood flow, Congenit Anom (Kyoto), 2016,56(1):28-34.

 7. Lv C, Wang X, Pang N, Wang L, Wang Y, Xu T, Zhang Y, Zhou T, Li W, The impact of airborne particulate matter on pediatric hospital admissions For pneumonia among Jinan children: a case-crossover study,J Air Waste Manag Assoc,2017 , 67 (6) :669-676.

8.Wei Li*, Xiangfeng Leng, Qiu Zhang, Cuifen Zhao4*, Chenguang Lv,Tengfei Xu,Nuclear localization signal of TGF-β-inducible nuclear protein 1 mediates functions of TINP1 in suppression of the p53 signaling pathway and promotion of cell proliferation, Int J Clin Exp Med , 2017-03,10(3):4748-4755

9.Xiaolin Sun, Haiying Weib, Dominique E. Youngd, Keith J. Beinc,Suzette M. Smiley-Jewellc, Qi Zhangd, Ciara Catherine B. Fulgarc, Alejandro R. Castañedac, Alexa K. Phamc, Wei Li*, Kent E. Pinkertonc,The impact of airborne particulate matter on pediatric hospital admissions For pneumonia among Jinan children: a case-crossover study,Toxicology Letters,2017-07,2781-8

10. .2017-09-29,一种基于图像处理的药瓶液位检测方法,发明

11.2017-09-29,基于机器视觉检测平台的液体药瓶异物检测方法,发明

12.2017-11-21,弓型臂螺旋加压式复位钳,实用新型

13.2018-06-30,一种血栓切除系统,实用新型

      

马德东:

1. Ma D, Lu H, Qu Y, et al. Primary Sjögren’s syndrome accompanied by pleural effusion: a case report and literature review[J]. International journal of clinical and experimental pathology, 2015, 8(11): 15322.    IF1.643    第一作者

2. Ma D, Lu H, Zhang C, et al. Use of polarized light microscopy is essential in the efficient diagnosis of respiratory amyloidosis and could decrease disease prevalence[J]. The clinical respiratory journal, 2017, 11(6): 691-695.   IF2.021    第一作者

3. Lu H, Zhang H, Zhang D, et al. A biocompatible reconstituted high-density lipoprotein nano-system as a probe for lung cancer detection[J]. Medical science monitor: international medical journal of experimental and clinical research, 2015, 21: 2726.    IF1.8    通讯作者

4. Wang W, Ying Y, Wu Q, et al. A GIS-based spatial correlation analysis for ambient air pollution and AECOPD hospitalizations in Jinan, China[J]. Respiratory medicine, 2015, 109(3): 372-378.    IF3.611    共同通讯作者

5. Ma D, Lu H, Qu Y, et al. Developing an effective therapeutic by delivery of synthetic microRNA-520e in lung cancer treatment[J]. Biomedicine & Pharmacotherapy, 2015, 69: 249-254.    IF3.224    第一作者

6. Ma D, Zhang R, Sun Y, et al. A novel role of periostin in postnatal tooth formation and mineralization[J]. Journal of Biological Chemistry, 2011, 286(6): 4302-4309. IF4.254(被选为当期封面照片)    第一作者

7. Ma D, Barragan-Adjemian C, Xie Y, et al. Pre-odontoblasts, odontoblasts, or" odontocytes"[J]. Journal of Dental Research, 2008, 87(3): 199.    IF5.716    第一作者

8. Ma D, Lu H, Xu L, et al. Mechanical loading promotes Lewis lung cancer cell growth through periostin[J]. In Vitro Cellular & Developmental Biology-Animal, 2009, 45(8): 467-472.    IF1.36    第一作者

9. Ma D D, Lu H X, Xu L S, et al. Polyphyllin D exerts potent anti-tumour effects on Lewis cancer cells under hypoxic conditions[J]. Journal of International Medical Research, 2009, 37(3): 631-640.    IF1.379    第一作者

10. Liu Y, Ying Y, Pandu J S, et al. Efficacy and safety assessment of expiratory positive airway pressure (EPAP) mask for OSAHS therapy[J]. Auris Nasus Larynx, 2019, 46(2): 238-245.    IF 1.387    共同通讯作者

国内期刊:

1. 刘雅璇, 应央央, 王岩, 窦双, 李延忠, & 马德东. (2017). 呼气正压鼻塞治疗阻塞性睡眠呼吸暂停低通气综合征的安全性和疗效评估. 山东大学耳鼻喉眼学报, 31(1), 31-37. 共同通讯作者

2. 王川;马德东;肖伟 等. 济南市城市居民慢性阻塞性肺病现状调查及相关危险因素分析[J]. 山东大学学报医学版, 2011 492):128-132.  共同第一作者

3. 马德东, 陈宏礼, 肖伟. 肺发育不全误诊为气流受限疾病一例[J]. 中华结核和呼吸杂志, 2009, 32(12): 958-959.     第一作者

(四) 出版书籍(内容包括:主编姓名、参编章节、书名、出版社、出版时间)

陈学良 等主编 临床实习医师手册-4版 人民卫生出版社2011-12-1 ISBN9787117149822

陈荣昌主编  呼吸与危重症医学2017-2018 北京:中华医学电子音像出版社,2018.8  ISBN978-7-83005-075-7        第八部分 睡眠呼吸障碍:治疗策略与方法的优化  12.具有二氧化碳监测功能的远程无创呼吸机在睡眠呼吸疾病中的应用P645

(五) 参与指南、共识及规范制定(内容包括:指南/共识/规范名称、制定负责人、发表时间、发表期刊)

(六) 参与国家行业标准制定(内容包括:行业标准名称、行业标准负责人、制定时间等)

(七) 申请专利(内容包括:专利名称、申请时间等)

发明专利

1.   2013.7 CT and MRI Synchronous Detection Positioning NeedleUS8588888B2   PCT/CN11/00716       第一发明人

2.   2011.04.13 一种CTMRI同步检测定位针(201110001927.3) 第一发明人

3.   2015.06.01 变压无创正压通气方法及应用该方法的医用呼吸机(ZL 2015 1 0292476.1) 第一发明人

4.   2015.03.11 一种基于智能手机的肺功能传感器(201410714201.8) 第一发明人

5.   2013.11.27 一种随体位变化调节呼气正压的通气面罩(201310334941.4) 第一发明人

新型设计专利

1.   2011.04.27 双音频应答交互数据传输装置(201020574007.1) 第一发明人

2.   2011.12.21 一种GPRS无线睡眠监测仪(201120171807.3) 第一发明人

3.   2012.10.31 一种基于体外膈肌起搏的睡眠呼吸暂停治疗装置(201220045744.1) 第一发明人

4.   2013.11.27 一种具有呼气正压的通气鼻塞(201310316347.2) 第一发明人

5.   2015.02.18 一种具有体外膈肌起搏功能的呼气正压通气面罩(201410716981.X)  第一发明人

6.   2015.03.11 一种吸/呼相压力比可反向调节的无创呼吸机(201410714202.2) 第一发明人

7.   2011.04.27 医疗数据播送系统(201020574008.6) 第一发明人

8.   2012.05.30 一种医疗数据采集装置(201120331514.7) 第一发明人

9.   2012.03.21 一种基于光波的吸入药物药量检测器(201110300093.6) 第一发明人

10.  2011.05.04 基于手机的肺功能监控系统(201020573995.8) 第一发明人

11.  2012.05.23 一种基于音频传输的肺功能监控系统(201120355441.5) 第一发明人

12.  2012.05.30 一种基于音频的肺功能传感器(201120355500.9) 第一发明人

13.  2011.04.27 纤支镜经鼻气管插管引导器(201020545730.7) 第二发明人

14.  2011.12.21 一种脉冲震荡雾化诱导痰装置(201120171140.7) 第一发明人

15.  2012.04.04 一种气流频率调节装置(201120235226.1) 第一发明人

16.  2011.12.21 一种射频震荡雾化诱导痰装置(201120172003.5) 第一发明人

17.  2012.05.30 一种吸入药物记录器(201120355459.5) 第一发明人

18.  2011.04.20 小动物喉镜(201020545657.3)第二发明人

19.  2016.08.24 一种带可插拔的SD卡的呼吸机系统(201620100477.1) 第一发明人

20.  2012.07.04 一种动物支气管肺癌模型的建立方法及装置(201210031560.4) 第一发明人

21.  2012.11.07 一种肺功能传感器(201210253737.5) 第一发明人

22.  2012.10.17 一种肺功能仪(201210253738.X) 第一发明人

23.  2011.05.11 一种气管镜管径测量器(201020557684.2) 第一发明人

24.  2013.11.27 一种全肺强迫振荡频谱检测系统(201310334081.4) 第一发明人


Kent E. Pinkerton

1.PM研究的新方向

Castañeda AR, Pinkerton KE, Bein KJ, Magaña-Méndez A, Yang HT, Ashwood P, Vogel CFA. 2018. Ambient particulate matter activates the aryl hydrocarbon receptor in dendritic cells and enhances Th17 polarization. Toxicol Lett. 292:85-96. PMID: 29689377; PubMed Central PMCID: PMC5971007.

 

Hopkins LE, Laing EA, Peake JL, Uyeminami D, Mack SM, Li X, Smiley-Jewell S, Pinkerton KE. 2018. Repeated Iron-Soot Exposure and Nose-to-brain Transport of Inhaled Ultrafine Particles. Toxicol Pathol. 46(1):75-84. PMID: 28914166

 

Sun X, Wei H, Young DE, Bein KJ, Smiley-Jewell SM, Zhang Q, Fulgar CCB, Castañeda AR, Pham AK, Li W, Pinkerton KE. 2017. Differential pulmonary effects of wintertime California and China particulate matter in healthy young mice. Toxicol Lett. 278:1-8. PMID: 28698096; PubMed Central PMCID: PMC5572813.

 

Plummer LE, Carosino CM, Bein KJ, Zhao Y, Willits N, Smiley-Jewell S, Wexler AS, Pinkerton KE. 2015. Pulmonary inflammatory effects of source-oriented particulate matter from California's San Joaquin Valley. Atmos Environ 119:174-181. PMID: 26568698; PubMed Central PMCID: PMC4639935.

2.    PM的收集、分析和生物效应研究

Mirowsky JE, Jin L, Thurston G, Lighthall D, Tyner T, Horton L, Galdanes K, Chillrud S, Ross J, Pinkerton KE, Chen LC, Lippmann M, Gordon T. 2015. In vitro and in vivo toxicity of urban and rural particulate matter from California. Atmos Environ 103:256-262. PMID: 26478712; PubMed Central PMCID: PMC4606878.

 

Van Winkle LS, Bein K, Anderson D, Pinkerton KE, Tablin F, Wilson D, Wexler AS. 2015. Biological dose response to PM2.5: effect of particle extraction method on platelet and lung responses. Toxicol Sci. 143(2):349-59. PMID: 25389146; PubMed Central PMCID: PMC4306718.

 

Madl AK, Plummer LE, Carosino C, Pinkerton KE. 2014. Nanoparticles, lung injury, and the role of oxidant stress. Annu Rev Physiol. 76:447-65. PMID: 24215442; PubMed Central PMCID: PMC4408931.

3. 气候变化

Rice MB, Motto Malea N, Pinkerton KE, Schwartz J, Nadeau KC, Browner CM, Whitehouse S, Thurston GD. 2018. Realizing the Paris Climate Agreement to Improve Cardiopulmonary Health. Where Science Meets Policy. Ann Am Thorac Soc. 15(7):791-798. PMID: 29652522

 

Bayram H, Bauer AK, Abdalati W, Carlsten C, Pinkerton KE, Thurston GD, Balmes JR, Takaro TK. 2017. Environment, Global Climate Change, and Cardiopulmonary Health. Am J Respir Crit Care Med. 195(6):718-724. PMID: 27654004; PubMed Central PMCID: PMC5363965.

 

Rice MB, Thurston GD, Balmes JR, Pinkerton KE. 2014. Climate change. A global threat to cardiopulmonary health. Am J Respir Crit Care Med. 189(5):512-9. PMID: 24400619; PubMed Central PMCID: PMC3977715.

4.环境与肺发育

Cole E, Brown TA, Pinkerton KE, Postma B, Malany K, Yang M, Kim YJ, Hamilton RF Jr, Holian A, Cho YH. 2017. Perinatal exposure to environmental tobacco smoke is associated with changes in DNA methylation that precede the adult onset of lung disease in a mouse model. Inhal Toxicol. 29(10):435-442. PMID: 29124997; PubMed Central PMCID: PMC6114174.

 

Christensen S, Jaffar Z, Cole E, Porter V, Ferrini M, Postma B, Pinkerton KE, Yang M, Kim YJ, Montrose L, Roberts K, Holian A, Cho YH. 2017. Prenatal environmental tobacco smoke exposure increases allergic asthma risk with methylation changes in mice. Environ Mol Mutagen. 58(6):423-433. PMID: 28543436; PubMed Central PMCID: PMC5513771.

 

Brown TA, Holian A, Pinkerton KE, Lee JW, Cho YH. 2016. Early life exposure to environmental tobacco smoke alters immune response to asbestos via a shift in inflammatory phenotype resulting in increased disease development. Inhal Toxicol. 28(8):349-56. PMID: 27138493; PubMed Central PMCID: PMC5109924.

我的书目中已发表工作的完整列表:

https://www.ncbi.nlm.nih.gov/sites/myncbi/kent.pinkerton.1/bibliography/41148594/public/?sort=date&direction=ascending