2024
Wenqiu Xu,
Jiayi Liu,
Yuzhu Zhang,
Yilu Tang,
Shihao Xu,
Xiaojian Li,
Xiaojian Li,
Xiaojian Li,
Xiaojian Li,
Xiuqing Su,
Binfa Liang#, Xiuqing Su#,
Qiqi Shi#, YuZhu Zhang#,
Yue Guan#, Yiwen Wang#, Chenghui Liao#, Huijie Ma*, Chenyang Li*.
Yue Guan#, Yingying Han#, Chenghui Liao#, Huijie Ma*, Chenyang Li*.
Qin Gong#, Yifan Song#,
Peng Yi#, Yaping Guo#,
Binfa Liang,
Jiahua Lu,
Jin Zhang#, Xiaoling Cheng#, Gang Chen#, Xiya Chen, Xi Zhao, Weiji Chen, Hailing Wang, Dabo Pan, Jinhui Wang, Jian Huang, Zhendan He, Chenyang Li*, Xiaojun Yao*, Dahong Yao*. Design, Synthesis and Biological Evaluation of Novel PAK1/HDAC10 Dual Inhibitors with pyrido[2,3-d]pyrimidin-7(8H)-one scaffold for the Treatment of Triple Negative Breast Cancer. (Submitted)
Guichan Huang#, Hailing Wang#, Xi Zhao, Dahong Yao*, Chenyang Li*. Design, Synthesis and Biological Evaluation of new SIRT3 Activators forthe Treatment of Triple-Negative Breast Cancer. (Submitted)
Jianwei Wang#, Xiaojia Lv#, Ying Li, Haiqiang Wu, Meiwan Chen, Hua Yu, Jianwei Wu , Chenyang Li*, Wei Xiong*. A ROS-responsive hydrogel that targets inflamed mucosa to relieve ulcerative colitis by reversing intestinal mucosal barrier loss. (Submitted)
Chenyang Li#, Shuai Wang#, Chenghui Liao, Ying Li, Yunfeng Zhou, Haiqiang Wu, Wei Xiong. An in situ sustained-release chitosan hydrogel to attenuate renalfibrosis by retaining klotho expression. Biomaterials Research, 2024. (中科院大类1区,JCR Q1,IF=8.1)
Yi Du#, Xiya Chen#, Weiji Chen, Gang Chen, Xiaoling Cheng, Hailing Wang, Chenyang Li*, Dahong Yao*. Design, Synthesis and Biological Evaluation of a Novel PAK1 degrader for the Treatment of Triple Negative Breast Cancer. Bioorganic & Medicinal Chemistry, 2024, 112: 117896. (中科院大类3区,JCR Q1,IF=3.3)
Yun-Shi Zhi#, Tie Chen#, Bin-Fa Liang, Qin Gong, Xiu-Qing Su, Shan Jiang, Da-Hong Yao, Zhen-Dan He, Chen-Yang Li*, Liang He*, Zheng-Yin Pan*. Endoplasmic Reticulum-Targeted Iridium(III) Photosensitizer Induces Pyroptosis for Augmented Tumor Immunotherap. Journal of Inorganic Biochemistry, 2024, 260, 112695. (中科院大类2区,JCR Q1,IF=3.8)
Ruirui Yu, Xiaojian Li, Peng Yi, Ping Wen, Shuhong Wang, Chenghui Liao, Xun Song, Haiqiang Wu, Zhendan He*, Chenyang Li*. Isolation and Identification of Chemical Compounds from Agaricus blazei Murrill and Their In Vitro Antifungal Activities. Molecules, 2023, 28(21), 7321. (中科院大类2区,JCR Q2,IF=4.6)
李晨阳*, 熊炜, 李颖, 郝悦, 陈铁, 王晓冬, 赵韵诗, 王子梅, 吴海强*. “创新创业”型教育模式在药学人才培养上的探究. 药学教育, 2023.(核心期刊,影响因子:1.14)
Ya-Ping Guo, Peng Yi, Qi-Qi Shi, Rui-Rui Yu, Jin-Hui Wang, Chen-yang Li*, Hai-Qiang Wu*. Cytotoxic Compounds from Belamcanda chinensis (L.) DC Induced Apoptosis in Triple-Negative Breast Cancer Cells. Molecules, 2023, 28(12), 4715. (中科院大类2区,JCR Q2,IF=4.927)
Zhengyin Pan, Binfa Liang, Yunshi Zhi, Dahong Yao*, Chenyang Li*, Hai-Qiang Wu* and Liang He*. Near-infrared AIE-active phosphorescent iridium(III) complex for mitochondria-targeted photodynamic therapy. Dalton Transactions, 2023. (中科院大类2区,JCR Q1,IF=4.569)
2022
Ying Li, Guoxing Deng, Xianlong Hu, Chenyang Li, Xiaodong Wang, Qinchang Zhu, Kai Zheng, Wei Xiong, Haiqiang Wu. Recent advances in mesoporous silica nanoparticle-based targeted drug-delivery systems for cancer therapy. Nanomedicine, 2022, 17(18), 1253-1279. (中科院大类2区,JCR Q1,IF=6.096)
Xiaopeng Hu, Ruirui Yu, Chenyang Li*. Experimental validation and virtual docking of anti-influenza effects of robinin based on network pharmacology. Experimental and Therapeutic Medicine. 2022. (中科院大类4区,JCR Q4,IF=2.751)
Xiao-Peng Hu#, Ya-Ping Guo#, Tie Chen, Er-Jie Chen, Yi Du, Qian Zhang, Peng Yi, Rui-Rui Yu, Yun-Shi Zhi, Chen-Yang Li*. Isolation, Structure Elucidation, and In-vitro Evaluation of New Trisubstituted Tetrahydrofuran Lignins from Rabdosia lophanthoides var. gerardiana as anti-inflammatory agents. Phytochemistry Letters. 2022, 52, 76-81. (中科院大类4区,JCR Q3,IF=1.873)
Mengxun Zhang#, Yi Du#, Liping Huang, Qinchang Zhu, Chenyang Li*, Zhendan He*. Electromediated Aldol Reaction in EtOH/H2O. Journal of The Electrochemical Society. 2022, 169(7), 075501. (中科院大类3区,JCR Q2,IF=4.386)
Qian Zhang#, Mengxun Zhang#, Yingchao Wang, Tingting Zhen, Roujuan Wang, Shuhong Wang, Yi Du, Ruirui Yu, Peng Yi, Yifan Song, Yunshi Zhi, Xun Song, Yaping Guo, Zhendan He, Tie Chen, Chenyang Li*. Natural compound 2-chloro-1,3-dimethoxy-5-methylbenzene, isolated from Hericium erinaceus, inhibits fungal growth by disrupting membranes and triggering apoptosis. Journal of Agricultural and Food Chemistry. 2022, 70(21), 6444–6454. (中科院大类1区,JCR Q1,IF=5.279)
2021
Xiaopeng Hu#, Tie Chen#, Shuquan Zhang, Qian Zhang, Chenyang Li*, Xiaodong Wang*. Anti-tumor effect of Odoroside A and its derivative on human leukemia cells through the ROS/JNK pathway. Basic & Clinical Pharmacology & Toxicology. 2021, 130(1), 56-59. (中科院大类3区,JCR Q2,IF=4.084)
Huiling Hong, Yiu Ming Cheung, Xiaoyun Cao, Yalan Wu, Chenyang Li, Xiao Yu Tian. REV-ERB alpha agonist SR9009 suppresses IL-1 beta production in macrophages through BMAL1-dependent inhibition of inflammasome. Biochemical Pharmacology. 2021, 192. (中科院大类2区,JCR Q1,IF=5.858)
Mengxun Zhang, Jiaqing Zhong, Yongai Xiong, Xun Song, Chenyang Li*, Zhendan He*. Development of Broad-Spectrum Antiviral Agents-Inspiration from Immunomodulatory Natural Products. Viruses. 2021, 13(7), 1257. (中科院大类2区,JCR Q2,IF=5.048)
Jonathan Shpigelman#, Fitzgerald S. Lao#, Shiyin Yao, Chenyang Li, Tetsuya Saito, Fumi Sato-Kaneko, John P. Nolan, Nikunj M. Shukla, Minya Pu, Karen Messer, Dennis A. Carson, Maripat Corr, Tomoko Hayashi*. Generation and application of a reporter cell line for the quantitative measurement of extracellular vesicle release. Frontiers in Pharmacology. 2021, 12, 668609. (中科院大类2区,JCR Q1,IF=5.81)
Yongai Xiong, Muhammad Shahid Riaz Rajoka, MengXun Zhang, Ning Liang, Chenyang Li*, Zhendan He*. Virucidal activity of Moringa A from Moringa oleifera seeds against Influenza A Viruses by regulating TFEB. International Immunopharmacology. 2021, 95, 107561. (中科院大类3区,JCR Q1,IF=4.932)
Mengxun Zhang#, Tie Chen, Shisong Fang, Weihua Wu, Xin Wang, Haiqiang Wu, Yongai Xiong, Jun Song, Chenyang Li*, Zhendan He*, Chi-Sing Lee*. Peroxide- and transition metal-free electrochemical synthesis of α,β-epoxy ketones. Organic & Biomolecular Chemistry. 2021, 19(11), 2481-2486. (中科院大类3区,JCR Q1,IF=3.876)
Tongxin Song#, Pengli Wang#, Chenyang Li#, Qianqian Liang, Yuanlin Cao, Pengzhi Dong, Hong Shi, Miaomiao Jiang*. Salidroside simultaneously reduces de novo lipogenesis and cholesterol biosynthesis to attenuate atherosclerosis in apoE-deficient mice. Biomedicine & Pharmacotherapy. 2021, 134, 111137. (中科院大类2区,JCR Q1,IF=6.529)
Chen-Yang Li#, Xiao-Jun Zhong#, Xiao-Peng Hu, Qin-Chang Zhu, Hai-Tao Xiao, Peng Zhai, Da-Hong Yao, Muhammad Shahid Riaz, Zhen-Dan He*, Xun Song*. Modulation of antiviral cytokine production and lung protection against influenza virus by the glycosides from Ligustrum purpurascens. Asian Toxicology Research. 2021, 3 (1): 3.
2020
Qianqian Pang#, Weiyang Zhang#, Chenyang Li#, Haibo Li, Yu Zhang, Lin Li, Caixia Zang, Xinsheng Yao, Dan Zhang*, Yang Yu*. Antidementia effects, metabolic profiles and pharmacokinetics of GJ-4, a crocin-rich botanical candidate from Gardeniae fructus. Food & Function. 2020, 11(10), 8825-8836. (中科院大类1区,JCR Q1,IF=5.396)
Dahong Yao#, Chenyang Li#, Muhammad Shahid Riaz Rajoka, Zhendan He, Jian Huang, Jinhui Wang*, Jin Zhang*. P21-Activated Kinase 1: Emerging biological functions and potential therapeutic targets in Cancer. Theranostics. 2020, 10(21), 9741-9766. (中科院大类1区,JCR Q1,IF=11.556)
Dahong Yao#, Chenyang Li#, Jin Jiang, Jian Huang, Jinhui Wang, Zhendan He*, Jin Zhang*. Design, synthesis and biological evaluation of novel HDAC inhibitors with improved pharmacokinetic profile in breast cancer. European Journal of Medicinal Chemistry. 2020, 205, 112648. (中科院大类2区,JCR Q1,IF=6.514)
Xiaobin Li#, Chenyang Li#, Yongqiang Zhu, Yongping Shi, Xuanming Zhang, Shanshan Zhang, Lizhen Wang, Houwen Lin, Hairong Hou, Chung-Der Hsiao, Liwen Han*, Kechun Liu*. Lipid Fingerprinting of Different Material Sources by UPLC-Q-Exactive Orbitrap/MS Approach and Their Zebrafish-Based Activities Comparison. Journal of Agricultural and Food Chemistry. 2020, 68(7), 2007-2015. (中科院大类1区,JCR Q1,IF=5.279)
Prior to 2020
Yuanlin Cao, Menghan Zhang, Yunfang Lu, Chenyang Li*, Jinshan Tang, Miaomiao Jiang*. Cardenolides from the leaves of Nerium oleander. Fitoterapia, 2018, 127, 293-300. (中科院大类3区,JCR Q3,IF=2.527)
Xiaodong Wang#, Chenyang Li#, Miaomiao Jiang, Dong Li, Ping Wen, Xun Song, Junda Chen, Lixuan Guo, Xiaopeng Hu, Guoqiang Li, Jian Zhang, Chunhua Wang*, Zhendan He*. Induction of apoptosis in human leukemia cells through an intrinsic pathway by cathachunine, a unique alkaloid isolated from Catharanthus roseus. Phytomedicine, 2016, 23(6), 641-653. (中科院大类2区,JCR Q1,IF=4.268)
Jiangtao Zhou#, Chenyang Li#, Chunhua Wang*, Yuefei Wang, Xiaodong Wang, Hongtao Wang, Yan Zhu, Miaomiao Jiang*, Xiumei Gao. Phenolic compounds from the roots of Rhodiola crenulata and their antioxidant and inducing IFN-γ production activities. Molecules, 2015, 20, 13725-13739. (中科院大类3区,JCR Q2,IF=3.267)
李晨阳#, 王晓冬, 郝悦, 贺震旦, 谢苗. 对我国现有药学课程改革与创新的思考.药学教育. 2015, (5), 9-13. (核心期刊,影响因子:1.14)
Chenyang Li#, David Taiwai Lau#, Tina Tingxia Dong, Jian Zhang, Roy Chiyan Choi, Haiqiang Wu, Liyan Wang, Ruisha Hong, Shihe Li, Xun Song, Tian Yu, Weiwei Su, Karl Wahkeung Tsim*, Zhendan He*. Dual-Index Evaluation of Character Changes in Panax ginseng C. A. Mey Stored in Different Conditions. Journal of Agricultural and Food Chemistry, 2013, 61 (26): 6568-6573. (中科院大类1区,JCR Q1,IF=4.192)
Xun Song#, Chenyang Li#, Yong Zeng, Haiqiang Wu, Zhong Huang, Jian Zhang, Ruisha Hong, Xianxiong Chen, Liyan Wang, Xiaopeng Hu, Weiwei Su, Yan Li*, Zhendan He*. Immunomodulatory effects of crude phenylethanoid glycosides from Ligustrum purpurascens. Journal of Ethnopharmacology, 2012, 144 (3): 584-591. (中科院大类3区,JCR Q1,IF=3.690)
Chenyang Li#, Hao Gao, Weihua Jiao, Long Zhang, Guangxiong Zhou, Xinsheng Yao*. Three new diterpenoids from Rabdosia lophanthoides var. gerandiana. Helvetica Chimica Acta, 2010, 93 (3): 450-456. (中科院大类4区,JCR Q3,IF=2.309)
专利
姚新生, 高昊, 赵峰, 李晨阳, 王国才, 焦伟华, 张龙, 贺飞, 戴毅, 姚志红, 周光雄, 叶文才. 复方消炎利胆制剂的质量控制方法. 中国. 公布号: CN101361793.
姚新生, 高昊, 赵峰, 焦伟华, 李晨阳, 贺飞, 戴毅, 姚志红, 周光雄, 叶文才. 苦木中的β-卡巴林类生物碱及其制备方法和用途. 中国. 公布号: CN101367802.
贺震旦, 廖程晖, 宋勋, 胡小鹏, 李晨阳. 紫茎女贞总苷诱导抗病毒细胞因子的应用. 专利号:ZL 2015 1 0083455.9. 授权日:2018年5月1日。
王春华, 李晨阳, 王晓冬, 王跃飞, 朱彦, 李东. 化合物、其提取方法、包含其的药物组合物及其用途. 专利号:ZL 2015 1 0108820.7. 授权日:2017年2月1日。
陈铁, 李璟端, 王绍祥, 李晨阳, 舒兴盛, 常港, 陈家杰. 一种新的胃癌肿瘤干细胞杀伤剂及其应用. 专利号:ZL 2018 1 0923567.4. 授权日:2020年11月27日。
熊炜, 王健伟, 李晨阳, 李颖. 一种可用于结肠炎症的制剂及其制备方法. 申请号:2023102254726。
李晨阳,韩颖颖,廖程晖,吴海强,郝悦. 一种射干流分的制备方法及其在制备抗单纯疱疹病毒 1 型药物上的应用. 申请号:202410068995.9。
李晨阳,廖程晖,吴海强,郝悦,陈铁,张羽竹. 一种二萜类化合物及其制备方法和应用. 申请号:2024112907136
专著
李晨阳等编著,《中药学》[M],天津科技出版社,2020年10月。
李晨阳等编著,《药学技能综合实训》[M],中国海洋出版社,2020年10月。
贺震旦、赵韵诗、李晨阳等编著,《常用中药毒性成分分析与结构鉴定》[M],科学出版社,2020年10月。
获奖
冬青属药用植物与苦丁茶的药效物质及其在感冒灵中的应用. 2020年度高等学校科学研究优秀成果奖科技进步奖一等奖。
贺震旦, 吴序栎, 宋勋, 李晨阳, 胡小鹏. 深圳大学. 苦丁茶资源科学、物质基础及其功效机制研究. 2020年度深圳市科学技术奖,自然科学类二等奖(排名第四)。
深圳市优秀教师,2023、2024。
深圳大学腾讯益友奖“优秀班主任”,2016、2021。
深圳大学百篇优秀本科毕业论文指导教师,2017。
深圳大学学生创新发展基金基础实验项目一等奖(2015)和优秀奖(2015)。
深圳大学“优秀实习指导教师”,2021、2022。
深圳大学2020-2021学年教学单项奖“优秀本科课程”奖,(生药学),2022。