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成果及论文

近五年代表成果列表(第一或通讯作者):

48. Ying Dong,§ Fangzhi Hu,§ Huixin Wu, Feng-Wei Guo, Liang Wang, Feng-Yu Du,* Shuai-Shuai Li*, Controllable Synthesis of N-Heterocycles via Hydride Trans-fer Strategy-enabled Formal [5+1] and [5+2] Cyclizations, Org. Lett. 2024, DOI 10.1021/acs.orglett.3c03986. (IF = 5.2, 中科院top一区)

 

47. Zhipeng Sun,§ Ranran Hou,§ Shuai-Shuai Li,* Xinyu Wang, Liang Wang, Fangzhi Hu,* Feng-Wei Guo*, Controllable Synthesis of N-Containing and O-Containing Heterocycles via Formal [3+2] and [5+2] Cyclizations, Org. Lett. 2024, DOI 10.1021/acs.orglett.3c03227. (IF = 5.2, 中科院top一区)

 

46. Fangzhi Hu, Zhipeng Sun, Mengzhe Pan, Liang Wang, Lubin Xu, Xiong-Li Liu, Shuai-Shuai Li*, Divergent synthesis of nitrogen heterocycles via H2O-mediated hydride transfer reactions, Green Chem. 2023, 25, 5134–5141. (IF = 9.8, 中科院top一区) 

45. Lianyi Cao, Fangzhi Hu, Jiacheng Dong, Xiao-Mei Zhang,* Shuai-Shuai Li*, Aromatization-driven cascade [1,5]-hydride transfer/cyclization for synthesis of spirochromanes, Org. Chem. Front. 2023, 10, 1796-1802. (IF = 5.456, 中科院top一区)

44. Yufeng Wang, Qiang Li, Xiaopei Song, Jing Wang, Xiangcong Yin, Shuai-Shuai Li*, Liang Wang*, Chemoselective and diastereoselective construction of 4-alkylidene-tetrahydroquinoline via a redox-neutral vinylogous cascade [1,7]-hydride transfer/6-endo-trig cyclization strategy, Org. Biomol. Chem. 2023, 21, 4007–4012. (IF = 3.89, 中科院三)

 

43. 陈玉琢, 孙红梅,  , 胡方芝*, 李帅帅*, 基于 α-氢迁移策略构建杂环骨架的研究进展, 有机化学, 2023, 43, 23232337. Invited Review

 


42. Yao-Bin Shen, Fangzhi Hu, Shuai-Shuai Li*, Alkyl amines and ethers as traceless hydride donors in [1,5]-hydride transfer cascade reactions, Org. Biomol. Chem. 2023, 21, 700-714. Invited Review (IF = 3.89, 中科院三)

 

41. Fangzhi Hu, Liang Wang, Peng Wang, Zhanshuai Ding, Yuzhuo Chen, LubinXu, Xiong-Li Liu, Shuai-Shuai Li*, Switchable construction of oxa-heterocycles with diverse ring sizes via chemoselective cyclization controlled by dibrominated compounds, Org. Chem. Front. 2022, 9, 6187-6193. (IF = 5.456, 中科院top一区)

 

40. Yao-Bin Shen, Fangzhi Hu, Shuai-Shuai Li*, Advances in α-C(sp3)–H functionalization of ethers via cascade [1,n]-hydride transfer/cyclization, Tetrahedron 2022, 127, 133089. Invited Review (IF = 2.388, 中科院三)

39. Fangzhi Hu, Yao-Bin Shen, Liang Wang, Shuai-Shuai Li*, Merging dearomatization with redox-neutral C(sp3)–H functionalization via hydride transfer/cyclization: recent advances and perspectives, Org. Chem. Front. 2022, DOI 10.1039/d2qo01054b. Invited Review (IF = 5.456, 中科院top一区)

38. Ronghao Xie, Shixiao Chen, Yufeng Wang, Xiangcong Yin, Shuai-Shuai Li*, Lubin Xu and Liang Wang*, Controllable construction of pharmaceutically significant scaffolds of 2,3-dihydroquinolin-4-one and benzoazepine-5-one via redox-neutral cascade hydride transfer/cyclization, Org. Chem. Front. 2022, DOI 10.1039/d2qo01103d. (IF = 5.456, 中科院top一区)

37. Chunyan Ge, Liang Wang, Fangzhi Hu, Zhanshuai Ding, Xinyao Li, Deshuai Xiao, Jiayi Wang, Shuai-Shuai Li*, HFIP-mediated imidization of electron-rich arenes with in situ formed spiroindolenines as new imidization reagents for facile construction of 2-arylspiroindolenines, Org. Chem. Front. 2022, 9, 1696-1702. (IF = 5.456, 中科院top一区)

 

36. Lianyi Cao, Fangzhi Hu, Hongmei Sun, Xiaomei Zhang,* Shuai-Shuai Li*, Redox-triggered dearomative [5+1] annulation of indoles with O-alkyl ortho-oxybenzaldehydes for synthesis of spirochromanes, Org. Chem. Front. 2022, 9, 1668-1674. (IF = 5.456, 中科院top一区)


35. Fangzhi Hu, Xinyao Li, Zhanshuai Ding, Liang Wang, Chunyan Ge, Lubin Xu, and Shuai-Shuai Li*, Divergent Synthesis of [3,4]-Fused 3‑Alkenyl-Oxindoles via Propargyl Alcohol-Triggered C(sp3)−H Functionalization, ACS Catal. 2022, 12, 943-952. (IF = 13.084, 中科院top一区)  

34. Ronghao Xie, Shixiao Chen, Xianping Xiang, Xiangcong Yin, Lubin Xu, Shuai-Shuai Li,* Liang Wang* and Fengying Dong, Diastereoselective construction of structurally diverse 2,3-dihydroquinolin-4-one scaffolds via redox neutral cascade [1,7]-hydride transfer/cyclization, Org. Chem. Front. 2022, DOI 10.1039/d1qo01530c. (IF = 5.281, 中科院top一区)

33. Fangzhi Hu, Liang Wang, Chunyan Ge, Xinyao Li, Zhanshuai Ding, Lubin Xu, Shuai-Shuai Li*Divergent α-Functionalization of Cyclic Amines via Ring Construction by Molecular O2 Oxidized Dearomatization and Ring Deconstruction by Aromatization Driven C-C σ-Bond Cleavage, Green Chem., 2021, 23, 5535–5541 (IF = 10.18, 中科院top一区)

32. Mengzhu Guo, Fengying Dong, Xiangcong Yin, Lubin Xu, Liang Wang*, and Shuai-Shuai Li*, Facile Syntheses of Tetrahydroquinolines and 1,2-Dihydroquinolines via Vinylogous Cascade Hydride Transfer/Cyclization, Org. Chem. Front. 2021, 8, 2224–2231. (IF = 5.281, 中科院top一区)

31. Xiaoyu Yang, Jianlin Liu, Fangzhi Hu, Hongmei Sun, Liang Wang*, and Shuai-Shuai Li*, Diverse Application of 4-Hydroxycoumarin in Syntheses of Tetrahydroquinoline and Zwitterionic Biscoumarin Derivatives, Chin. J. Org. Chem., 2021, 41, 2788-2799. (中国期刊 有机化学》,中科院三区) 

30. Xiaoyu Yang, Liang Wang, Fangzhi Hu, Lubin Xu, Sanming Li, and Shuai-Shuai Li*, Redox-Triggered Switchable Synthesis of 3,4-Dihydroquinolin-2(1H)-one Derivatives via Hydride Transfer/N-Dealkylation/N-Acylation, Org. Lett. 2021, 23, 358–364. (IF = 6.005, 中科院top一区)

29. Kejin Yuan, Fengying Dong, Xiangcong Yin, Shuai-Shuai Li*, Liang Wang,* Lubin Xu, The dual alkylation of the C(sp3)-H bond of the cyclic α-methyl-N-sulfonyl imines via sequential condensation/hydride transfer/cyclization process, Org. Chem. Front. 2020, 7, 3868–3873. (IF = 5.281, 中科院top一区)

28. Yingying Xing, Fengying Dong, Xiangcong Yin, Liang Wang* and Shuai-Shuai Li*, Facile Construction of 3,4-dihydro-2H-1,2,4-Benzothiadiazine 1,1-Dioxides via Redox-Neutral Cascade Condensation/[1,7]-Hydride Transfer/Cyclization, Asian J. Org. Chem. 2020, 9, 1787-1792. (IF = 3.319, 中科院三区)

27. Kang Duan, Hongjin Shi, Lin-Xuan Wang, Shuai-Shuai Li*, Lubin Xu, Jian Xiao*, Hydride Transfer Enabled Switchable Dearomatization of Indoles in the Carbocyclic Ring and the Pyrrole Ring, Org. Chem. Front. 2020, 7, 2511–2517. (IF = 5.281, 中科院top一区)



26. Fangzhi Hu, Liang Wang, Lubin Xua and Shuai-Shuai Li*, Aromatization-driven deconstruction/refunctionalization of unstrained rings, Org. Chem. Front. 2020, 7, 1570–1575. (IF = 5.076, JCR分区, 一区)

                                                                        

25. Xiaoyu Yang, Fangzhi Hu, Liang Wang, Lubin Xu and Shuai-Shuai Li*, Hydrogen-bonding-assisted redox-neutral construction of tetrahydroquinolines via hydride transfer, Org. Biomol. Chem. 2020, 18, 4267–4271. (IF = 3.490, JCR分区, 三区)

24.  Hongjin Shi, Liang Wang, Shuai-Shuai Li,* Yongjun Liu, and Lubin Xu*, Divergent syntheses of spirooxindoles from oxindole-embedded four-membered synthon via cycloaddition reactions, Org. Chem. Front. 2020, 7, 747–755. (IF = 5.076, JCR分区, 一区)

23. Hongjin Shi, Lubin Xu, Didi Ren, Liang Wang,* Weisi Guo and Shuai-Shuai Li*, Fluorinated alcohol mediated N,N’-dialkylation of amino acid derivatives via cascade [1,5]-hydride transfer/cyclization for concise synthesis of tetrahydroquinazoline, Org. Biomol. Chem. 2020, 18, 895-904. (IF = 3.490, JCR分区, 三区)

22.  Lan Zhou, Yao-Bin Shen, Xiao-De An, Xian-Jiang Li, Shuai-Shuai Li*, Qing Liu, and Jian Xiao*, Redox-Neutral β‑C(sp3)−H Functionalization of Cyclic Amines via Intermolecular Hydride Transfer, Org. Lett. 2019, 21, 8543−8547. (IF = 6.555, JCR分区, 一区)

21.  Guangxian Bai, Fengying Dong, Lubin Xu, Yongjun Liu, Liang Wang,* and Shuai-Shuai Li*, Controllable Syntheses of Spiroindolenines and Benzazepinoindoles via Hexafluoroisopropanol-Mediated Redox-Neutral Cascade Process, Org. Lett. 2019, 21, 6225-6230. (IF = 6.555, JCR分区, 一区)

20.  Shuai-Shuai Li, Shuai Zhu, Chunqi Chen, Kang Duan, Qing Liu, and Jian Xiao*, Redox-Neutral Cascade Cyclizations for Construction of Spirocyclic Bisoxindoles Featuring a [3,4]-Fused Oxindole Moiety, Org. Lett2019, 21, 1058-1062. (IF = 6.555, JCR分区, 一区)

19.  Didi Ren, Lubin Xu, Liang Wang*, Shuai-Shuai Li*, Catalytic Formal Benzylic C−H Bond Functionalization of 2,5-Dialkylfuran Derivatives with Ferrocenyl Alcohols as Alkylation Reagents, Org. Lett2019, 21, 627–631. (IF = 6.555, JCR分区, 一区)

18.  Shuai Zhu, Chunqi Chen, Kang Duan, Yun-Ming Sun, Shuai-Shuai Li*, Qing Liu, and Jian Xiao*, Cascade [1,5]-Hydride Transfer/Cyclization for Synthesis of [3,4]-Fused Oxindoles, J. Org. Chem. 2019, 84, 8440−8448. (IF = 4.745, JCR分区, 二区)

17. Xintong Lv,# Fangzhi Hu,# Kang Duan, Shuai-Shuai Li*, Qing Liu, and Jian Xiao*, Aromatization-Driven Cascade [1,5]-Hydride Transfer/Spirocyclization Promoted by Fluorinated Alcohols, J. Org. Chem. 2019, 84, 1833-1844. (IF = 4.745, JCR分区, 二区)

16.  Shuai-Shuai Li, Xintong Lv, Didi Ren, Chang-Lun Shao, Qing Liu and Jian Xiao*, Redox-Triggered Cascade Dearomative Cyclizations Enabled by Hexafluoroisopropanol, Chem. Sci. 2018, 9, 8253–8259. (IF = 9.556, JCR分区, 一区)

15.  Shuai-Shuai Li,# Lan Zhou,# Liang Wang, Huaili Zhao, Liping Yu, and Jian Xiao*, Organocatalytic C(sp3)-H Functionalization via Carbocation-Initiated Cascade [1,5]-Hydride Transfer/Cyclization: Synthesis of Dihydrodibenzo[b,e]azepines, Org. Lett2018, 20, 138-141. (IF = 6.555, JCR分区, 一区)

14.  Chunqi Chen, Lubin Xu, Liang Wang* and Shuai-Shuai Li*, Efficient construction of tetrahydroquinolines via fluorinated alcohol mediated cascade [1,5]-hydride transfer/cyclization, Org. Biomol. Chem. 2018, 16, 7109–7114. (IF = 3.490, JCR分区, 三区)

13.  Shuai-Shuai Li, Shiheng Fu, Liang Wang, Lubin Xu, and Jian Xiao, t-BuOK-Mediated Oxidative Dehydrogenative C(sp3)-H Arylation of 2-Alkylazaarenes with Nitroarenes, J. Org. Chem. 201782, 8703. (IF = 4.745, JCR分区, 二区)

12.  Shuai-Shuai Li, Lin Wu, Liu Qin, Yu-Qin Zhu, Fu Su, Yan-Jun Xu*, Lin Dong*, Iridium(III)-catalyzed Tandem [3 + 2] Annulation: Synthesis of Spirocyclic Phosphoramide Derivatives, Org. Lett2016, 18, 4214-4217. (IF = 6.555, JCR分区, 一区)

11.  Shuai-Shuai Li, Cheng-Qi Wang, Hui Lin, Xiao-Mei Zhang, Lin Dong*, Rhodium(III)-Catalyzed Oxidative Annulation of 7‑Azaindoles and Alkynes via Double C-H Activation, Org. Lett. 201517, 3018-3021. (IF = 6.555, JCR分区, 一区)

10.  Shuai-Shuai Li, Hui Lin, Chen-Fei Liu, Ying-Qi Xia, Xiao-Mei Zhang, Lin Dong*, Rhodium-Catalyzed Tandem Annulation Reactions of 7-Azaindoles with Electron-Deficient Olefins via Double C-H Activation, Adv. Synth. Catal. 2016, 358, 1595-1601.

9.  Shuai-Shuai Li#, Ying-Qi Xia#, Chen-Fei Liu, Guo-Tai Zhang, Xiao-Mei Zhang, Lin Dong*, Diverse Reactivity in a Rhodium(III)-Catalyzed Vinylic sp2 C–H Bond Functionalization: Synthesis of Fused Polycyclic Heteroarenes or Conjugated Dienes, Adv. Synth. Catal. 2016, 358, 3724-3729.

8.  Shuai-Shuai Li#, Chen-Fei Liu#, Guo-Tai Zhang, Ying-Qi Xia, Wei-Huan Li, Lin Dong*, A Convenient One-Pot Route to Screw-Shaped [5]Azahelicenes via Rhodium(III)-Catalyzed Multiple C−H Bond Activation, Chemistry – An Asian Journal 2017, 12, 415-418.

7.   Shuai-Shuai Li, Ying-Qi Xia, Fang-Zhi Hu, Chen-Fei Liu, Xiao-Mei Zhang, Lin Dong*, IrIII-Catalyzed One-Pot Cascade Synthesis of Pentacyclic-Fused Carbazoles from Indoles and Diazoes, Chemistry – An Asian Journal 2016, 11, 3165-3168.

6.  Shuai-Shuai Li, Cheng-Qi Wang, Hui Lin, Xiao-Mei Zhang, Lin Dong*, Rhodium(III)-catalyzed C–C coupling of 7-azaindoles with vinyl acetates and allyl acetates, Org. Biomol. Chem. 2016, 14, 229-237.

5.  Shuai-Shuai Li#, Liu Qin#, Lin Dong*, Rhodium-catalyzed C–C Coupling Reactions via Double C–H Activation, Org. Biomol. Chem. 2016, 14, 4554-4570. (过渡金属铑催化双C-H活化综述,高被引论文)


4.  Shuai-Shuai Li, Chen-Fei Liu, Ying-Qi Xia, Xiao-Mei Zhang, Lin Dong*, A Unique Annulation of 7-Azaindoles with Alkenyl Esters to Produce π-Conjugated 7-Azaindole Derivatives, Org. Biomol. Chem. 2016, 14, 5214-5218.

3.  Shuai-Shuai Li#, Wei-Huan Li#, Guo-Tai Zhang, Ying-Qi Xia, Xiao-Mei Zhang, Lin Dong*, One-pot Construction of Fused Polycyclic Heteroarenes Involving 7-Azaindoles and α,β-Unsaturated Ketones, Org. Biomol. Chem. 2016, 14, 7859-7863.

2.  Shuai-Shuai Li, Hui Lin, Xiao-Mei Zhang, Lin Dong*, Ruthenium-catalyzed direct C3 alkylation of indoles with α,β-unsaturated ketones, Org. Biomol. Chem. 2015, 13, 1254-1263.

1.  Shuai-Shuai Li, Cheng-Qi Wang, Wei-Huan Li, Xiao-Mei Zhang, Lin Dong*, Rhodium-catalyzed Selective Oxidative Coupling of 7-Azaindoles, Tetrahedron 2016, 72, 2581-2586.


非第一及通讯作者论文:

10. Yao-Bin Shen, Shuai-Shuai Li, Xicheng Liu, Liping Yu, Yun-Ming Sun,* Qing Liu, and Jian Xiao*, Formal [4 + 2] Annulation of Oxindole-Embedded ortho-Quinone Methides with 1,3-Dicarbonyls: Synthesis of Spiro[Chromen-4,3’-Oxindole] Scaffolds, J. Org. Chem. 2019, 84, 3990−3999.

9. Yao-Bin Shen, Shuai-Shuai Li, Yun-Ming Sun, Liping Yu, Zhi-Hui Hao,* Qing Liu, and Jian Xiao*, Organocatalytic C(sp3)−H Functionalization of 5‑Methyl-2,3-dihydrofuran Derivatives with Trifluoropyruvates via a Sequential exo-Tautomerization/Carbonyl-Ene Process, J. Org. Chem. 2019, 84, 2779−2785.

8. Yao-Bin Shen, Shuai-Shuai Li, Xicheng Liu, Liping Yu,* Qing Liu, Jian Xiao*, Dearomative [4+2] Cycloaddition of Oxindole-Embedded orthoQuinone Methides with 2,5-Dialkylfurans, Adv. Syn. Catal. 2019, 361, 1453.

7. Liping Yu, Shuai-Shuai Li, Weina Li, Shitao Yu,* Qing Liu, and Jian Xiao*, Fluorinated Alcohol-Promoted Reaction of Chlorohydrocarbons with Diverse Nucleophiles for the Synthesis of Triarylmethanes and Tetraarylmethanes, J. Org. Chem. 2018, 83, 15277-15283.

6. Shuai Wang, Xiao-De An, Shuai-Shuai Li, Xicheng Liu, Qing Liud and Jian Xiao*, Hydride transfer initiated ring expansion of pyrrolidines toward highly functionalized tetrahydro-1-benzazepines, Chem. Commun. 2018, 54, 13833-13836.

5. Yao-Bin Shen, Shuai-Shuai Li, Liang Wang, Xiao-De An, Qing Liu, Xicheng Liu, and Jian Xiao*, Organocatalytic Dearomative [4+2] Cycloadditions of BiomassDerived 2,5-Dimethylfuran with ortho-Quinone Methides: Access to Multisubstituted Chromanes, Org. Lett. 2018, 20, 6069−6073.

4. Mingyan Xiao, Didi Ren, Lubin Xu, Shuai-Shuai Li, Liping Yu, and Jian Xiao*, SN1‑Type Alkylation of N‑Heteroaromatics with Alcohols, Org. Lett. 2017, 19, 5724−5727.

3. Haoxun Dong, Lubin Xu, Shuai-Shuai Li, Liang Wang, Chang-Lun Shao, and Jian Xiao*, Facile Synthesis of Azaarene-Substituted Hydroxycoumarins Possessing High Biological Activities via Three-Component C(sp3)−H Functionalization, ACS Comb. Sci. 2016, 18, 604−610.

2. Wei-Huan Li, Lin Wu, Shuai-Shuai Li, Chen-Fei Liu, Guo-Tai Zhang, and Lin Dong*, Rhodium-Catalyzed Hydrogen-Releasing ortho-Alkenylation of 7-Azaindoles, Chem. Eur. J. 2016, 22, 17926-17929.

1. Hui Lin, Shuai-Shuai Li and Lin Dong*, Synthesis of indoles and polycyclic amides via ruthenium(II)-catalyzed C–H activation and annulation, Org. Biomol. Chem. 2015, 13, 11228–11234.


授权专利:

1. 3,4-二氢-3-(2-羟基苯甲酰)-2(1H)-喹啉酮活性骨架及合成方法和应用专利号:ZL 201910530179.4

发明人:李帅帅、胡方芝、王亮、徐鲁斌、杨晓宇

2. 一种氧气促进的去芳香化反应在构建螺环二烯酮骨架中的应用 (专利号:ZL 202110792351.0)   

发明人:李帅帅、胡方芝、李鑫瑶

3. 一种双香豆素内盐生物活性骨架的绿色合成方法及应用 (专利号:ZL 202110224263.0)   

发明人:李帅帅、胡方芝、王亮、徐鲁斌、杨晓宇



1、一种3,4-二氢-3-(2-羟基苯甲酰)-2(1H)-喹啉酮生物活性骨架及其合成方法和应用,201910530179.42020.08.041/5

2、一种苯酚类化合物的苄基化合成方法,201810725188.42020.07.212/3

3、一种基于靛红骨架的苯并[b,e]氮杂卓化合物及其制备方法,201810979889.02019.12.103/4

4、一种氮杂环取代对醌骨架螺环化合物的合成方法,201810733970.02020.05.193/3