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成果及论文

Total Synthesis of (±)- and (−)-Daphnillonin B

Zou, Y.-P.; Lai, Z.-L.; Zhang, M.-W.;  Peng, J.-Z.; Ning, S.; Li, C.-C.*

J. Am. Chem. Soc., 2023xxx, xxxx.  [doi]


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Strategies and Lessons Learned from Total Synthesis of Taxol

Min, L.; Han, J.-C.; Zhang, W.; Gu, C.-C.; Zou, Y.-P.; Li, C.-C.*

Chem. Rev., 2023123, 4934.  [doi]


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Asymmetric Total Synthesis of Twin Bufogargarizins A and B

Zhong, L.-P.; Feng, R.; Wang, J.-J.; Li, C.-C.*

J. Am. Chem. Soc., 2023145, 2098.  [doi]

• Highlighted in ChemistryViews, 01/2023

•  Highlighted in X-MOL, 01/2023

• Top 20 Most Accessed Article in 02/2023

•  Highlighted in HUAXUEJIA (化学加), 01/2023


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Total Synthesis of Yuzurine-type Alkaloid Daphgraciline

Li, L.-X.; Min, L.; Yao, T.-B.; Ji, S.-X.; Qiao, C.; Tian, P.-L.; Sun, J.-W;* Li, C.-C.*

J. Am. Chem. Soc., 2022144, 18823.  [doi]

•  Highlighted in X-MOL, 10/2022

•  Top 5 Most Read Article in 10-11/2022

•  Highlighted in Synfacts, 12/2022 (Synfact of the Month)

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Asymmetric Total Syntheses of Hypoestin A, Albolic Acid, and Ceroplastol II

Wang, Y-Q.; Xu, K.-H.; Min, L.; Li, C.-C.*

J. Am. Chem. Soc., 2022144, 10162.  [doi]

• Highlighted in ChemistryViews,  06/2022

• Highlighted in HUAXUE JIA (化学加),  06/2022

• Highlighted in SUSTech News, 06/2022

• Highlighted in Synfacts202218, 0942

Publications(图1)


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Asymmetric Total Synthesis of Taxol

Hu, Y.-J.; Gu, C.-C.; Wang, X-F.; Min, L.; Li, C.-C.*

J. Am. Chem. Soc., 2021143, 17862.  [doi]

• Highlighted in SUSTech News, 10/2021

• Highlighted in HUAXUE JIA (化学加), 10/2021

• Highlighted in Rationalscience  (微信公众号:研之成理),10/2021

• Highlighted in NSFC, 10/2021

• Highlighted in CBG 资讯, 10/2021

• Top 5 Most Accessed Article in 10-11/2021

• Highlighted in Synfacts202218, 5

• Highlighted in Chin. J. Org. Chem2021

• Top 10 Most Accessed Article in 10/2021-now

• Highlighted in Org. Chem. Highlights, 04/2022

Publications(图1)

Publications(图1)


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Facile generation of bridged medium-sized polycyclic systems by rhodium-catalysed intramolecular (3+2) dipolar cycloadditions

 Hou, B-L.; Jonathan J. Wong.; Lv, N.; Wang, Y-Q.; K. N. Houk*.; Li, C.-C.*

Nat. Comm., 202112, 5239.  [doi]

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Synthesis of natural products containing highly strained trans-fused bicyclo[3.3.0]octane: historical overview and future prospects

Zhang, W.; Li, L-Z.; Li, C.-C.*

Chem. Soc. Rev., 2021. [doi]

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Recent advances in total syntheses of natural products containing the benzocycloheptane motif

Fan, J.-H.; Hu, Y.-J.; Li, L.-X.; Wang, J.-J.; Li, S.-P.; Zhao, J* Li, C.-C.*

Nat. Prod. Rep., 2021. [doi]


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Asymmetric Total Synthesis of Phomarol

Fan, J.-H.; Wang, J.-J.; Li, F.; Wang, G.; Guo, Q.; Chung, L.-W.; Li, C.-C.*

CCS Chem., 2021, 3, 348.  [doi]

• Highlighted in X-MOL2021

• Highlighted in CBG 资讯2021

• Highlighted in SUSTech News2021

Publications(图1)


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Asymmetric Total Synthesis of the Highly Strained Acetoxyprobotryane-diol

Zhang, W.; Zhou, Z.-X.; Zhu, X.-J.; Sun, Z.-H.; Dai, W.-M.; Li, C.-C.*

J. Am. Chem. Soc., 2020, 142, 19868. [doi]

• Highlighted in X-MOL, 11/2020

• Highlighted in HUAXUE JIA (化学加), 11/2020 

• Highlighted in CBG 资讯, 11/2020

• Highlighted in SUSTech News, 12/2020 

Publications(图1)


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Synthetic Applications of Type II Intramolecular Cycloadditions

Min, L.; Hu, Y.-J.; Fan, J.-H.; Zhang, W.; Li, C.-C.*

Chem. SocRev., 2020, 49, 7015.  [doi]

• Highlighted in HUAXUE JIA, 09/2020.

• Highlighted in SUSTech News, 09/2020.

Publications(图1)


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Asymmetric Total Synthesis of Bufospirostenin A

Cheng, M.; Zhong, L.; Gu, C.-C.; Zhu, X.-J.; Chen, B.; Liu, J.-S.; Wang, L*.; Ye, W.-C*.; Li, C.-C*

J. Am. Chem. Soc., 2020142, 12602.  [doi]

• Highlighted in NANOER, 07/2020.

• Highlighted in OrgChemNews, 07/2020

• Highlighted in X-MOL, 07/2020.

• Highlighted in HUAXUE JIA, 07/2020.

• Highlighted in CBG, 07/2020.

• Highlighted in SUSTech News, 07/2020.

• Highlighted in Liang 's Medicinal Chemistry, 07/2020.

• Highlighted in Total Synthesis, 08/2020.

• Top 5 Most Read Article in 07-08/2020. 

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Recent Advances in the Total Synthesis of Natural Products Containing Eight-Membered Carbocycles (2009−2019)

Hu, Y.-J.; Li, L.-X.; Han, J.-C.; Min, L.; Li, C.-C* 

Chem. Rev., 2020120,  5910.  [doi]


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 Unusual KIE and Dynamics Effects in the Fe-catalyzed Hetero-Diels-Alder Reaction of Unactivated Aldehydes and Dienes

Yang, Y.; Zhang, X.; Zhong, L.; Lan, J.; Li, X.; Li, C.-C.; Chung, L.-W.

Nat. Comm., 2020. 53703  [doi]


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Leptosperols A and B, Two Cinnamoylphloroglucinol−Sesquiterpenoid Hybrids from Leptospermum scoparium: Structural Elucidation and Biomimetic Synthesis

Gu, J.; Wang, W.; Chen, J.; Liu, J.; Li, N.; Cheng, M.; Hu, L.; Li, C.-C.*; Ye, W.-C.*; Wang, L.* 

Org. Lett.2020, 22, 1796.   [doi]  


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Total Synthesis of Natural Products with Bridged Ring Systems via Type II [5+2] Cycloaddition

Min, L.; Liu, X.; Li, C.-C*

Acc. Chem. Res., 202053, 703.  [doi]

• Highlighted in HUAXUE JIA, 02/2020. 

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Total Synthesis of Natural Products Containing a Bridgehead Double Bond

Liu, J.; Liu, X.; Wu, J.; Li, C.-C* 

Chem., 20206, 579.  [doi]

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Asymmetric Total Synthesis of (−)-Vinigrol

Min, L.; Lin, X.; Li, C.-C*

J. Am. Chem. Soc., 2019141, 15773.  [doi]                         

• Highlighted in SUSTech NEWS, 09/2019.                                         

• Top 5 Most Accessed Article in 10/2019

• Highlighted in HUAXUE JIA, 10/2019.   

• Highlighted in  Liang's  Medicinal chemistry, 10/2019.    

• Highlighted in Chemical Science News, 09/2019.                       

• Highlighted in ChemistryViews, 10/2019.

• Highlighted in NSFC Center for Science Communication, 10/2019


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 Asymmetric Total Synthesis of Cerorubenic Acid-III

Liu, X.; Liu, J.; Wu, J.; Huang, G.; Liang, R.; Chung,L.-W.; Li, C.-C*

J. Am. Chem. Soc., 2019, 141, 2872.  [doi] 

• Top 5 Most Accessed Article in 03/2019

• Highlighted in Synfacts, 05/2019.  

• Highlighted in HUAXUE JIA, 02/2019.  

• Highlighted in X-MOL, 02/2019.  

• Highlighted in Chin. J. Org. Chem2019.  

• Highlighted in SUSTech NEWS, 02/2019

 


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 Asymmetric Total Synthesis of Cyclocitrinol

Liu, J.; Wu, J.; Fan, J.-H.; Yan, X.; Mei, G.; Li, C.-C* 

J. Am. Chem. Soc., 2018140,  5365.  [doi]  

• Highlighted in SUSTech NEWS, April, 2018.  

• Top 5 Most Read Article in 04-05/2018

• Highlighted in HUAXUE JIA, April, 2018.  

• Highlighted in X-MOL, July, 2018.  

• Highlighted in Chin. J. Org. Chem., August, 2018.


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Asymmetric Total Syntheses of Callistrilones B, G and J

Hu, L.; Cheng, M.; Cao, J.; Zhong, L.; Hu, Y.; Wang, Y.; Wang, L.*; Ye, W.-C.*; Li, C.-C* 

Org. Chem. Front., 2018, 5, 1506.  [doi]    

 


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 Recent Synthetic Study towards Natural Products via (5+2) Cycloaddition

Liu, X.; Hu, Y.-J.; Fan, J.-H. Zhao, J.*; Li, S.*; Li, C.-C.*

Org. Chem. Front.20185, 1217.  [doi]

 

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 Catalytic Asymmetric Total Synthesis of Myrtucommuacetalones and Callistrilones 

Cheng, M.; Cao, J.; Yang, X.; Zhong, L.; Hu, L.; Lu, X.; Hou, B.; Hu, Y.; Wang, Y.; You, X.; Wang, L.*; Ye, W.-C.*; Li, C.-C* 

Chem. Sci., 20189, 1488.  [doi] 

• Highlighted in Royal Society of Chemistry, December, 2017.

• Highlighted in SUSTech NEWS, December, 2017.

 

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 Asymmetric Total Syntheses of Colchicine, beta-Lumicolchicine and Allocolchicinoid NCME

Liu, X.; Hu, Y.-J.; Chen, B. Min, L.; Peng, X.-S.; Zhao, J.*; Li, S.*; Wong, H. N. C.; Li, C.-C.*

Org. Lett., 2017, 19,  4612.  [doi]

ACS Editors' Choice

• Top 1 Most Accessed Article in 08-09/2017.

• Top 5 Most Accessed Article in 08/2017-09/2018.

 

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 Enantioselective Total Synthesis of (-)-Colchicine, (+)-Demecolcinone and Metacolchicine

Chen, B.; Liu, X.; Hu, Y.-J.; Zhang, D.-M.; Deng, L.J.; Lu, J.Y.; Min, L.; Ye, W.-C.; Li, C.-C.*

Chem. Sci., 20178, 4961.  [doi]

 

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 Toward the Total Synthesis of Eurifoloid A

Liu, X.; Liu, J.Y.; Zhao, J.*; Li, S.*; Li, C.-C.*

Org. Lett., 201719, 2742.  [doi] 

• Top 20 Most Accessed Article in 06/2017.

 

 

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 Synthetic Study toward the Total Synthesis of Solanoeclepin A

Liu, G.; Han, J.-C.; Li, C.-C.*

Tetrahedron.201773, 3629.  [doi]  

 

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 Recent Progress toward the Total Synthesis of Humulanolides

Han, J.-C.; Liu, X.; Zhao, J.; Li, S.; Li, C.-C.*

Tetrahedron., 201773, 3289.  [doi] 

        


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 Catalytic Enantioselective Total Synthesis of Hypocrolide A

Qiao, C.; Zhang, W.; Han, J.; Li, C.-C.*

Org. Lett., 2016, 18, 4932.  [doi]
• Top 10 Most Accessed Article in 10/2016.

• Top 20 Most Accessed Article in 09/2016-08/2017

 

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 Ruthenium-Catalyzed Metathesis Cascade Reactions in Natural Products Synthesis

Han, J.; Li, C.-C.*

The Chemial Record., 2017, 499.  [doi]

• An invited Account article.


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 Collective Synthesis of Natural Products Using Metathesis Cascade Reactions

Han, J.; Li, C.-C.*

Synlett., 201526, 1289.  [doi]

•  An invited Account article.     


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 Type II Intramolecular [5+2] Cycloaddition: Facile Synthesis of Highly Functionalized Bridged Ring Systems

Mei, G.; Liu, X.; Qiao, C.; Chen, W.; Li, C.-C.*

Angew. Chem. Int. Ed., 2015, 54, 1745.  [doi]

• Highlighted in Angew Cover2015.

• Highlighted in SUSTech NEWS, 2014.


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 Collective Synthesis of Humulanolides Using a Metathesis Cascade Reaction

Han, J.; Li, F.; Li, C.-C.*

J. Am. Chem. Soc., 2014136, 13610.  [doi] 

•  Highlighted in Synfacts, 2014, 10, 1234.

•  Highlighted in Chemicals & Chemistry, 2014, Pubz ID: 009477592.

•  Highlighted in SUSTech NEWS2014.
•  Highlighted in ChemInform, March, 2015.


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 Dearomative Indole [5+2] Cycloaddition Reactions: Stereoselective Synthesis of Highly Functionalized Cyclohepta[b]indoles

Mei, G.; Yuan, H.; Gu, Y.; Chen, W.; Chung, L.; Li, C.-C.*

Angew. Chem. Int. Ed., 201453, 11051. [doi]

• Highlighted in Chin. J. Org. Chem., December, 2014.

• Highlighted in ChemInform, March, 2015.

 

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 Total Synthesis of Aplykurodinone-1

Liu,G.; Mei, G.; Chen, R.; Yuan, H.; Yang, Z.*; Li, C.-C.*

Org.Lett.201416, 4380.  [doi]

• Top 10 Most Accessed Article in 08/2014.

• Highlighted in ChemInform, Februry, 2015.

• Top 20 Most Accessed Article in 08/2014-06/2015.

 

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 Stereoselective Total Syntheses of (−)-Flueggine A and (+)-Virosaine B

Wei, H.; Qiao, C.; Liu, G.; Yang, Z.*; Li, C.-C.*

Angew. Chem. Int. Ed.201352, 620.  [doi]

• Chosen as “Hot Paper” by the Editors.

• Top 3 Most Accessed Article in 11/2012.

• Highlighted in PKUSZ NEWS2012.

• Highlighted in Chemistry World, January, 2013.

• Highlighted in Synfacts2013, 9, 237 (“Synfact of the Month”).

 

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 Total Synthesis of (±)-Pentalenolactone A Methyl Ester

Liu, Q.; Yue, G.; Wu, N.; Lin, G.; Li, Y.; Quan, J.; Li, C.-C.*; Wang, G.*; Yang, Z.*

Angew. Chem. Int. Ed., 201251, 12072.  [doi]

• Top 10 Most Accessed Article in 10/2012.

• Highlighted in Chin. J. Org. Chem., January, 2013.

• Highlighted in Chemistry World, November, 2012.