2023
32. Kuanhui Xiang#, Yi-hua Zhou. Breastmilk-old but not obsolete: from the safety of breastfeeding during the coronavirus disease 2019 pandemic to broad antiviral drug development. Maternal-Fetal Medicine, 2023, doi.org/10.1097/FM9.0000000000000188
31. Tian Tian#, Huijun Dong#, Shengju Yin, Mengyuan Liu, Yongyan Chen, Kuanhui Xiang, Linlin Wang, Jie Qiao*, Aiguo Ren*. In Utero Exposure to Lead is Associated with Neural Tube Defectsvia Disturbing the Expression of Endocannabinoid Retrograde Signaling‑Related Genes. Exposure and Health, 2023, doi.org/10.1007/s12403-023-00564-x
30. Kuanhui Xiang*, Hui Zhuang. Liver organoid potential application for hepatitis E virus. Advances in Experimental Medicince and Biology, 2023, 1417:133-139.
29. Yang Yi#, Wenzhe Li#, Kefang Liu, Heng Xue, Rong Yu, Meng Zhang, Yang-Oujie Bao, Xinyuan Lai, Jingjing Fan, Yuxi Huanga, Jing Wang, Xiaomeng Shi, Junhua Li, Hongping Wei, Kuanhui Xiang, Linjie Li, Rong Zhang, Xin Zhao, Xue Qiao*, Hang Yang*, Min Ye*. Licorice-saponin A3 is a broad-spectrum inhibitor for COVID-19 by targeting viral spike and anti-inflammation. Journal of Pharmaceutical Analysis. 2023,
2022
27. Xinyuan Lai, Hui Zhuang, Tong Li, Kuanhui Xiang. Protocol for characterizing the inhibition of SARS-CoV-2 infection by a protein of interest in cultured cells. STAR Protocols, 2022, 101802.
26. Xing Tian#, Huijun Dong#, Xinyuan Lai, Guomin Ou, Junning Cao, Jihang Shi, Chengang Xiang, Lei Wang, Xuechao Zhang, Kai Zhang, Ji Song, Juan Deng, Hongkui Deng, Shichun Lu, Hui Zhuang*, Tong Li*, Kuanhui Xiang*. TRIM56 impairs HBV infection and replication by inhibiting HBV core promoter activity. Antiviral Research, 2022, 105406
25. Luo Yuqian*, Xiang Kuanhui*, Liu Jingli, Song Ji, Feng Jing, Chen Jie, Dai Yimin, Hu Yali, Zhuang Hui#, Zhou Yihua#. Inhibition of In Vitro Infection of Hepatitis B Virus by Human Breastmilk. Nutrients, 2022, 14(8):1561
24. Yi Yang*, Li Junhua*, Lai Xinyuan*, Zhang Meng*, Kuang Yi, Bao Yang-oujie, Yu Rong, Hong Wei, Muturi Elishiba, Xue Heng, Wei Hongping, Li Tong, Zhuang Hui, Qiao Xue, Xiang Kuanhui#, Yang Hang#, Ye Min#. Natural triterpenoids from licorice potently inhibit SARS-CoV-2 infection. Journal of Advanced Research, 2022, 36:201-210
23. Xiao Yiwei*, Cao Junning*, Zhang Ze, Zeng Chaoting, Ou Guomin, Shi Jihang, Liu Zhixiu, Li Yi, Deng Juan, Xu Yinzhe, Zhang Wenwen, Li Jie, Li Tong, Zhuang Hui#, Lu Shichun#, Xiang Kuanhui#. Hepatitis B virus pregenomic RNA reflecting viral replication in distal non-tumor tissues as a determinant of the stemness and recurrence of HCC. Frontiers in Microbiology, 2022, 13:830741
22. Zhou Yihua#, Luo Yuqian, Xiang Kuanhui. Thinking more about inhibition of breast milk on the infectivity of SARS-CoV-2. JAMA Pediatrics, 2022, 176(5):526-527
21. Lai Xinyuan*, Yu Yanying*, Xian Wei*, Ye Fei*, Ju Xiaohui, Luo Yuqian, Dong Huijun, Zhou Yihua, Tan Wenjie, Zhuang Hui, Li Tong, Liu Xiaoyun#, Ding Qiang#, Xiang Kuanhui#. Inhibition of in vitro SAR S-CoV-2 infection and replication by lactoferrin, mucin1 and α-lactalbumin identified in human breastmilk. iScience, 2022, 25(4):104136
20. Song Ji, Ou Guomin, Lai Xinyuan, Tian Xing, Wang Luwei, Zhang Kai, Wang Lei, Zhang Xuechao, Zhao Chengyu, Zhuang Hui, Xiang Kuanhui#, Li Tong#. The enhancement role of Matrigel on HBV infection in HepG2-NTCP cells. Journal of Virological Methods, 2022, 299:114345
2021
19. Tian Tian, Lai Xinyuan, Xiang Kuanhui, Han Xiao, Yin Shengju, Cabrera Robert M, Steele John W, Lei Yunping, Cao Xuanye, Finnell Richard H, Wang Linlin #, Ren Aiguo #. Hypermethylation of PI3K-AKT signalling pathway genes is associated with human neural tube defects. Epigenetics, 2021, 17;1-14
18. Ou Guomin, He Lingyuan, Wang Luwei, Song Ji, Lai Xinyuan, Tian Xing, Wang Lei, Zhang Kai, Zhang Xuechao, Deng Juan, Zhuang Hui #, Xiang Kuanhui #, Li Tong #. The Genotype (A to H) Dependent N-terminal Sequence of HBV Large Surface Protein Affects Viral Replication, Secretion and Infectivity. Frontiers in Microbiology, 2021, 12:687785
17. Zhang Kai *, Lai Xinyuan *, Song Ji, He Lingyuan, Wang Luwei, Ou Guomin, Tian Xing, Wang Lei, Deng Juan, Zhang Jiajia, Li Chuanyun, Zhuang Hui #, Li Tong #, Xiang Kuanhui #. A novel cell culture model reveals the viral interference during hepatitis B and C virus coinfection. Antiviral Research, 2021,189:105061
2020
16. Fan Huahao*, Hong Bixia*, Luo Yuqian*, Peng Qi*, Wang Liqin, Jin Xiangshu, Chen Yangzhen, Hu Yunjia, Shi Yi, Li Tong, Zhuang Hui, Zhou Yi-Hua#, Tong Yigang#, Xiang Kuanhui#. The effect of whey protein on viral infection and replication of SARS-CoV-2 and pangolin coronavirus in vitro. Signal Transduction and Targeted Therapy, 2020, 24;5(1):275
15. Chen Xinxin, Xiang Kuanhui, Zhang Haiping, Kong Xiangsha, Huang Chunyang, Liu Yanmin, Lou Jinli, Gao Zuhua, Yan Huiping#. Occult HBV infection in patients with autoimmune hepatitis: A virological and clinical study. Journal of Microbiology, Immunology and Infection, 2020, 53(6):946-954
2019
14. He Lingyuan; Su Mingze; Ou Guomin; Wang Luwei; Deng Juan; Zhuang Hui; Xiang Kuanhui#, Li Tong#. The modulation of HBsAg level by sI126T is affected by additional amino acid substitutions in the S region of HBV. Infection Genetics and Evolution, 2019, 20:104006
13. Xiang Kuanhui*, Xiao Yiwei, Li Yao, He Lingyuan, Wang Luwei, Zhuang Hui, Li Tong#. The effect of the hepatitis B virus surface protein truncated sC69∗ mutation on viral infectivity and the host innate immune response. Frontiers in Microbiology, 2019, 10:1341
12. Xie Bingqing, Sun Da, Du Yuanyuan, Jia Jun, Sun Shicheng, Xu Jun, Liu Yifang, Xiang Chengang, Chen Sitong, Xie Huangfan, Wang Qiming, Li Guangya, Lyu Xuehui, Shen Hui, Li Shiyu, Wu Min, Zhang Xiaonan, Pu Yue, Xiang Kuanhui, Lai Weifeng, Du Peng, Yuan Zhenghong, Li Cheng, Shi Yan#, Lu Shichun#, Deng Hongkui#. A two-step lineage reprogramming strategy to generate functionally competent human hepatocytes from fibroblasts. Cell Research, 2019, 29(9):696-710
11. Xiang Chengang, Du Yuanyuan, Meng Gaofan, Yi Liewsoon, Sun Shicheng, Song Nan, Zhang Xiaonan, Xiao Yiwei, Wang Jie, Yi Zhigang, Liu Yifang, Xie Bingqing, Wu Min, Shu Jun, Sun Da, Jia Jun, Liang Zhen, Sun Dong, Huang Yanxiang, Shi Yan, Xu Jun, Lu Fengmin, Li Cheng, Xiang Kuanhui, Yuan Z#, Lu S#, Deng H#. Long-term functional maintenance of primary human hepatocytes in vitro. Science, 2019, 364 (6438): 399-402
10. Hao Ran, Xiang Kuanhui, Shi Yan, Zhao Dong, Tian Huifang, Xu Baohong, Zhu Yufang, Dong Huan, Ding Hai, Zhuang Hui#, Hu Jie#, Li Tong#. Naturally occurring mutations within HBV surface promoter II sequences affect transcription activity, HBsAg and HBV DNA levels in HBeAg-positive chronic hepatitis B patients. Viruses, 2019, 11 (1) pii: E78
2018
9. Wu Xianfang, Dao Thi Viet Loan, Liu Peng, Takacs Constantin N, Xiang Kuanhui, Andrus Linda, Gouttenoire Jerome, Moradpour Darius, Rice Charles M#. Pan-genotype hepatitis E virus replication in stem cell-derived hepatocellular systems. Gastroenterology, 2018, 154(3):663-674
8. Xiang Kuanhui, Zhao Chengyu, Wang Shuai, Li Yao, Su Mingze, Wang Qiangyi, Xu Xizhan, Deng Juan, Zhuang Hui#, Li Tong#. Impacts of HBV rtH55R polymerase substitution on viral replication and rtM204I/V resistance to nucleos(t)ide antiviral drugs. Antiviral Therapy, 2018, 23(1):33-42
2017
7. Michailidis Elefterios, Pabon Jonathan*, Xiang Kuanhui*, Park Paul, Ramanan Vyas, Hoffmann Hans-heinrich, Schneider Williams M, Bhatia Shatia N, de Jong Ype P, Shlomai Amir, Rice Charles M. A robust cell culture system supporting the complete life cycle of hepatitis B virus. Scientific Reports, 2017, 7(1):16616
6. Xiang Kuanhui, Michailidis Eleftherios, Ding Hai, Peng Ya-qin, Su Ming-ze, Li Yao, Liu Xue-en, Dao Thi Viet Loan, Wu Xian-fang, Schneider William M, Rice Charles M, Zhuang Hui#, Li Tong #. Effects of amino acid substitutions in hepatitis B virus surface protein on virion secretion, antigenicity, HBsAg and viral DNA. Journal of Hepatology, 2017, 66:288-296
5. Peng Yaqin, Li Yutang, Hou Jinlin, Sun Jian, Su Mingze, Li Yao, Xiang Kuanhui, Yan Ling, zhuang Hui, Li Tong. The nucleotide changes within HBV core promoter/precore during the first 12 weeks of nucleos(t)ide treatment might be associated with a better virological response. Infection Genetics and Evolution, 2017; 49:116-121
4. Xu Xizhan, Xiang Kuanhui, Su Mingze, Li Yao, Ji Wei, Li Yao, Zhuang Hui#, Li Tong#. HBV drug resistance substitutions existed before the clinical approval of nucleos(t)ide analogues: a bioinformatic analysis by genbank data mining. Viruses, 2017; 9(8). pii: E199
2016
3. Su Mingze, Xiang Kuanhui, Li Yao, Deng Juan, Xu Xizhan, Yan Ling, Zhuang Hui#, Li Tong#. The higher detection rates of amino acid substitutions in reverse transcription/ surface protein overlapping sequence is correlated with lower serum HBV DNA and HBsAg levels in HBeAg-positive chronic hepatitis B patients with subgenotype B2 HBV infection. Infection Genetics and Evolution, 2016; 40:275-81
2015
2. Hao Ran, Xiang Kuanhui, Peng Yaqin, Hou Jinlin, Sun Jian, Li Yao, Su Mingze, Yan Ling, Zhuang Hui#, Li Tong#. Naturally occurring deletion/insertion mutations within HBV whole genome sequences in HBeAg-positive chronic hepatitis B patients are correlated with baseline serum HBsAg and HBeAg levels and might predict a shorter interval to HBeAg loss and seroconversion during antiviral treatment. Infection Genetics and Evolution, 2015; 33:261-268
1. Peng Yaqin, Li Yutang, Hou Jinlin, Sun Jian, Su Mingze, Li Yao, Xiang Kuanhui, Yan Ling, Zhuang Hui, Li Tong. Naturally occurring deletions/insertions in HBV core promoter tend to decrease in HBeAg-positive chronic hepatitis B patients during antiviral therapy. Antiviral Therapy, 2015; 20(6): 623-32
