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Kailong Li Principal investigator School of Basic Medical Sciences, Peking University
Dr. Kailong Li received his B.S. in Life Sciences from Wuhan University and Ph.D. in Pathology and Pathophysiology at Chinese Academy of Medical Sciences & Peking Union Medical College, where he studied the mechanisms that control pancreatic cancer metastasis under the mentorship of Dr. Limin Li. In September 2015, he joined Dr. Jian Xu's laboratory in Children's Research Institute at UT Southwestern Medical Center as a postdoctoral fellow and focused on the functional and molecular studies of non-coding regulatory DNA elements, particularly transcriptional enhancers, in blood stem cell differentiation and cancers. His studies with Dr. Jian Xu developed the CRISPR epigenetic editing toolsets, enCRISPRa and enCRISPRi for interrogation of enhancer function and an integrative framework to identify and functionally dissect non-coding regulatory variants in human diseases including cancer. In 2021, Dr. Li joined the faculty of School of Basic Medical Sciences, Peking University. Dr. Li is the recipient of the CPRIT training grant (2018, 2019), the Travel Award for Best Postdoc Poster, Cancer Biology Retreat (2019) and the Collaborator of the Year Award, CRI (2020).
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Our lab investigates the genetic and epigenetic mechanisms that control cancer and other disorders. Ongoing studies include: 1. Development and application of novel CRISPR-based epigenome editors 2. Epigenetic regulation in cancer progression and metastasis 3. Epigenetics of host-pathogen interactions
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