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成果及论文

52.  Pd-catalyzed enantioselective and regioselective asymmetric hydrophosphorylation and hydrophosphinylation of enynes. Yanxin Jiang, Kwai Wun Cheng, Zhiping Yang, Jun (Joelle) Wang.* Chin. Chem. Lett. 2024. Link


51.  Enantio- and Regioselective Cascade Hydroboration of Methylenecyclopropanes for Facile Access to Chiral 1,3- and 1,4-Bis(boronates). Jian Zhou,  Ling Meng,  Ziyi Yang,  Jun (Joelle) Wang.*  Adv. Sci. 2024, 2400096. Link


50. Ni-catalyzed propargylic substitution reaction: A general and versatile tool to assemble axially chiral phosphorus-containing allenes. Xiao-dong Gu, Ka Yan Ngai, Wei Wang, Bin Li, Jun (Joelle) Wang*,  Chem Catalysis, 4 (2024) 100903. Link



49. Palladium-catalyzed Enantio- and Regioselective Ring-Opening Hydrophosphinylation of Methylenecyclopropanes. Jian Zhou†, Ling Meng†, Shujuan Lin, Baohua Cai, Jun Wang*, Angew. Chem. Int. Ed. 2023, DOI: 10.1002/anie.202303727Link


48. Jiang, Y.; Cheng, K. W.; Zhang, H.; Yang, Z.; Wang, J., Palladium-Azaphos Catalyzed Asymmetric Suzuki-Miyaura Coupling. Synthesis. 2023, DOI: 10.1055/a-2069-4665 Link.


47. Research Progress on Synthesis of Thioflavonoids. Meng, L. Wang, J.* Chin. J. Org. Chem. 2023, 43, 873-891 (Invited review for issue of “Chinese Women Chemists”). Link


46. Organocatalytic construction of axially chiral phosphorus-containing arylpyrazoles. Luo, S.; Wang, J.* Chem Catal. 2023, 3, 100579 (preview)  Link


45. Enantioselective copper-catalyzed hydrophosphination of alkenyl isoquinolines. Yang, Q.; Zhou, J.; Wang, J., Chem. Sci. 2023, DOI: 10.1039/D2SC06950D. Link

44. Asymmetric Hydrophosphinylation of Alkynes: Facile Access to Axially Chiral Styrene-Phosphines. Cai, B.; Cui, Y.; Zhou, J.; Wang, Y.-B.; Yang, L.*; Tan, B.*; Wang, J.* Angew. Chem. Int. Ed.  2023135, e202215820, DOI: 10.1002/anie.202215820 Link


43. Nickel-catalyzed Enantioselective α-Heteroarylation of Ketones via C‒F bond Activation to Construct All-Carbon Quaternary Stereocenters. Gu, X.; Liu, K.; Yang, L. Xie, C.; Li, M.*; Wang, J.* Chem. Sci. 2022, 13, 12498–12502.  Link


42. Catalyst-free Regio- and Diastereoselective Synthesis of Heterocyclic Nucleosides in the Eco-friendly Solvent 2-Methyltetrahydrofuran. Gu, X.; Du, Q.; Song, W.; Wang, J.* Chin. J. Chem. 2022, 40, DOI: 10.1002/cjoc.202200550Link


41. Asymmetric synthesis of flavanols via Cu-catalyzed kinetic resolution of chromenes and their anti-inflammatory activity. Yang, Q.; Wang, Z.; Hor, C. H. H.; Xiao, H.; Bian, Z.*; Wang, J.* Sci. Adv. 2022, 8, DOI: 10.1126/sciadv.abm9603 . Link


40. Enantio- and Regioselective Construction of 1,4-Diamines via Cascade Hydroamination of Methylene Cyclopropanes. Zhou, J.; Yang, Q.; Lee, C. S.*; Wang, J.* Angew. Chem. Int. Ed. 2022, 61, doi.org/10.1002/anie.202202160 Link

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39. Palladium-Catalyzed Diastereo- and Enantioselective Desymmetric Hydrophosphination of Cyclopropenes. Zhang,Y.; Jiang, Y.; Li, M.; Huang, Z.; Wang, J.* Chem. Catal. 2022, doi.org/10.1016/j.checat.2022.08.008 . Link

 (Front Cover, Invited paper for special issue on asymmetric catalysis, New journal of Cell Press)

        


38. Synthetic and Computational Study of the Enantioselective [3+2]-Cycloaddition of Chromones with MBH Carbonates. Meng, L.; Liu, H.; Lin, Z.; Wang, J.* Org. Lett. 2022, 24, 5890–5895Link

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37. Nickel-Catalyzed Enantioselective C(sp3 )–H Arylation of Ketones with Aryl Ethers via Selective CAr–O Cleavage to Construct All-Carbon Quaternary Stereocenters. Li, M.; Wang, J.* CCS Chem. 2022, 4, 2921-2929 Link


35. Recent Advances on Transition-Metal-Catalyzed Asymmetric C–H Arylation Reactions. Li, M.; Wang, J.* Synthesis202254, 4734-4752. Link 


35. Enantioselective Palladium-Catalyzed Hydrophosphinylation of Allenes with Phosphine Oxides: Access to Chiral Allylic Phosphine Oxides. YangZ.WangJ.* Angew. Chem. Int. Ed. 2021, 60, 27288–27292. Link


34. Asymmetric Access of γ-AminoAcidsandγ-AminoPhosphonicAcidDerivatives via Copper-Catalyzed Enantioselective and Regioselective Hydroamination. YangZ.; DuQ.; JiangY.; WangJ.* CCSChem. 20224, 1901-1911Link

33. Kinetic Resolution of 2-Substitued 1,2-Dihydroquinolines by Rhodium-Catalyzed Asymmetric Hydroarylation. Cai, B.; Yang, Q.; Meng, L.; Wang, J.* Chin. J. Chem. 2021, 6, 1606-1610. Link

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32. Highly enantioselective access to chiral chromanes and thiochromanes via Cu-catalyzed hydroamination with antranils. Gu, X.; Meng. L.;  Li, M.; Wang, J.* Org. Chem. Front. 2021, 8, 1563-1568. Link

Graphical abstract: Highly enantioselective access to chiral chromanes and thiochromanes via Cu-catalyzed hydroamination with anthranils

 

31. Metal-free access to 3-allyl-2-alkoxychromanones via phosphine-catalyzed alkoxy allylation of chromones with MBH carbonates and alcohols. Meng, L.; ChangX.; LinZ.;* WangJ.* Org.Biomol.Chem. 2021, 19, 2663-2667. Link

Graphical abstract: Metal-free access to 3-allyl-2-alkoxychromanones via phosphine-catalyzed alkoxy allylation of chromones with MBH carbonates and alcohols

 

30. Catalytic mutual multicomponent reaction: facile access to alpha-trifluoromethylthiolated ketones. Jin, M.-Y.; Gu, X.; Deng, M; Wang, C.; Wang J.* Chem.Commun. 2020, 56, 10552-10555. Link

Graphical abstract: Catalytic mutual multicomponent reaction: facile access to α-trifluoromethylthiolated ketones

 

29. Palladium-Catalyzed Asymmetric Hydrophorylation of Alkynes: Facile Access to P-Stereogenic Phosphinates. Yang, Z.; Gu, X.; Han, L., Wang, J.* Chem. Sci. 2020, 11, 7451-7455. Link

 

28. Enantioselective synthesis of indole derivatives by Rh/Pd relay cataysis and their anti-inflammatory evaluation. Li, S.; Wang, Z.; Xiao, H.; Bian, Z.;* Wang, J.* Chem. Commun. 2020, 56, 7573-7576. Link

Graphical abstract: Enantioselective synthesis of indole derivatives by Rh/Pd relay catalysis and their anti-inflammatory evaluation 


27. Rhodium-Catalyzed Enantioselective Hydroselenation of Heterobicyclic Alkenes. Li, S.; Yang, Q.; Bian, Z.;* Wang, J.*  Org. Lett. 2020, 22, 2781-2785. Link

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26. Cu(I)-Catalyzed Enantioselective Alkynylation of Thiochromone. Meng, L.; Ngai, K.-Y. Chang, X.; Lin, Z.;* Wang, J.*  Org. Lett. 2020, 22, 1155-1159. Link

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25. Kinetic Resolution and Dyanmic Kinetic Resolution of Chromene by Rh-Catalyzed Asymmetric Hydroarylation. Yang, Q.; Wang, Y.; Luo, S.;  Wang, J.* Angew. Chem. Int. Ed. 201958, 5343-5347 (Highlighted in Synfacts, 2019, 15, 5343 and X-MOL). Link

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24. Asymmetric Hydrophosphination of Heterobicyclic Alkenes: Facile Access to Phosphine Ligands for Asymmetric Catalysis. Lu, Z.; Zhang, H.; Yang, Z.; Ding, N.; Meng, L.; Wang, J.* ACS Catal. 2019, 9, 1457-1463 (Highlighted by X-MOL). Link

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23. Phosphoric Acid Catalyzed Atroposelective Construction of Axially Chiral Arylpyrroles. Zhang, L.; Xiang, S.-H.; Wang, J.;* Tan, B.* Nat. Commun. 2019, 10, 566-575 (Highlighted by CBG news). Link

 


22. Asymmetric construction of atropisomeric biaryls via a redox neutral cross-coupling strategy. Qi, L.-W.; Li, S.; Xiang, S.-H.; Wang, J.*; Tan, B.* Nat. Catal., 2019, 314-323 (Highlighted by Chemical & Engineering News). Link

 

21. Sulfide-Catalyzed Trifluoromethylthiolation-Cyclization of Tryptamine Derivatives. Guo, R.*Cai, B.; Jin M.-Y.; Mu H.; Wang, J.* Asian J. Org. Chem. 2019, 8, 687-690. Link

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20. Cobalt-Catalyzed Direct C-H Thiolation of Aromatic Amides with Disulfides: Application to the Synthesis of Quetiapine. Li M.; Wang, J.* Org. Lett. 201820, 6490-6493. Link

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19. Catalytic Asymmetric Trifluoromethylthiolation of Carbonyl Compounds via a Diastereo- and Enantioselective Cu-Catalyzed Tandem Reaction. Jin, M.-Y.; Li, J.; Huang, R.; Zhou, Y.; Chung, L.-W.; Wang, J.* Chem. Commun. 201854, 4581-4584 (Highlighted in Synfacts201814, 0731). Link

Graphical abstract: Catalytic asymmetric trifluoromethylthiolation of carbonyl compounds via a diastereo and enantioselective Cu-catalyzed tandem reaction

 

18. Cobalt-Catalyzed Cross-Dehydrogenative Coupling of Imizazo[1,2-a]pyridines with Isochroman Using Molecular Oxygen as Oxidant. Yang, Q.; Li, S.; Wang, J.* Org. Chem. Front.20185, 577-581. Link

Graphical abstract: Cobalt-catalyzed cross-dehydrogenative coupling of imidazo[1,2-a]pyridines with isochroman using molecular oxygen as the oxidant

 

17. Cu-Catalyzed Conjugate Addition of Grignard Reagents to Thiochromones: An Enantioselective Pathway for Accessing 2-Alkylthiochromanones. Luo, S.; Meng, L.; Yang, Q.*; Wang, J.*  Synlett 201829, 2071-2075. Link

 

16. Atom-Economical and Stereoselective Difunctionalization of Electron-Withdrawing Alkynes with N-Trifluoromethylthiophthalimide. Li, J.; Yang, Z.;  Guo, R.; Jin, M.-Y.*; Wang, J.Asian J. Org. Chem. 20187, 1784-1787. Link

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15. A Highly Enantioselective Access to Chiral Chromanone and Thiochromanones by Copper- Catalyzed Asymmetric Conjugated Reduction of Chromones and Thiochromones. Xiong, D.; Zhou, W.; Lu, Z.; Zeng, S.; Wang, J.* Chem. Commun. 201753, 6844-6847 (Highlighted by X-MOL). Link

 


14. Iridium-Catalyzed Asymmetric Addition of Thiophenols to Oxabenzonorbornatienes. Li, S.; Lu, Z.; Meng, L.;  Wang, J.* Org. Lett.  2016, 18, 5276-5279  (Highlighted in Synfacts201612, 1272). Link

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13. Rh-Catalyzed Conjugate Addition of Arylzinc Chlorides to Thiochromones : A Highly Enantioselective Pathway for Accessing Chiral Thioflavanones. Meng, L.; Jin, M.-Y.; Wang, J.* Org. Lett. 2016, 18, 4986-4989 (Highlighted in Synfacts201713, 0048). Link

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12. Copper(II) triflate-catalyzed highly efficient synthesis of N-substituted 1,4-dihydropyridine derivatives via three-component cyclizations of alkynes, amines, and α, β-unsaturated aldehydes. Li, S.; Yang, Q.; Wang, J.* Tetrahedron Lett. 2016, 57, 4500-4504. Link

 

11. Bi(OTf)3-catalyzed addition of isocyanides to 2H-chromene acetals: an efficient pathway for accessing 2-carboxamide-2H-chromenes. Lyu, L.; Jin, M.-Y.; He, Q.; Xie. H.; Bian, Z.; Wang, J.* Org. Biomol. Chem. 201614, 8088-8091. Link

Graphical abstract: Bi(OTf)3-catalyzed addition of isocyanides to 2H-chromene acetals: an efficient pathway for accessing 2-carboxamide-2H-chromenes

 

10. Recent Progress on the Asymmetric Synthesis of Chiral Flavanones. Meng, L.; Wang, J.* Synlett. 2016, 27, 656-663 (Invited Account). Link

 


9. 1,4-Diazabicyclo[2.2.2]octane-Promoted Aminotrifluoromethylthiolation of α,β-Unsaturated Carbonyl Compounds: N-Trifluoromethylthio-4-nitrophthalimide Acts as Both the Nitrogen and SCF3. Xiao, Q.; He, Q.; Li, J.; Wang J.* Org. Lett. 201517, 6090-6093 (Highlighted by X-MOL). Link

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8. Palladium-Catalyzed Asymmetric Ring Opening Reaction of Azabemzpmprbp,adoemes with Aromatic Amines. Lu, Z.; Wang, J.;Han, B.; Li, S.; Zhou, Y.; Fan, B.* Adv. Synth. Catal. 2015, 357, 3121-3125 (Highlighted in Synfacts201511, 1296) . Link

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7. Palladium/Zinc Co-catalyzed Syn-Stereoselectively Asymmetric Ring Openting Reaction of Oxabenzonorbomadienes with Phenols. Li, S.; Xu, J.; Fan, B.* Lu, Z.; Zeng, C.; Bian, Z.; Zhou, Y.; Wang, J.* Chem. Eur. J. 2015, 21, 9003-9007 (Inside Cover). Link

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6. AlCl3-Catalyzed O-Alkylative Passerini Reaction of Isocyanides, Cinnamaldehydes and Various Aliphatic Alcohols for Accessing α-Alkoxy-β,γ-Enamides. Lyu, L., Xie, H.; Mu, H., He, Q.; Bian, Z.*; Wang, J.* Org. Chem. Front. 2015, 2, 815-818. Link

Graphical abstract: AlCl3-catalyzed O-alkylative Passerini reaction of isocyanides, cinnamaldehydes and various aliphatic alcohols for accessing α-alkoxy-β,γ-enamides

 

5. Rhodium/Chiral Diene-Catalyzed Asymmetric 1,4-Addition of Arylboronic Acids to Chromones: A Highly Enantioselective Pathway for Accessing Chiral Flavanones. He, Q.-J; So, C.-M.; Bian, Z.; Hayashi, T.; Wang, J.* Chem. Asian. J. 201510, 540-543. Link

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4. Iridium/copper-cocatalyzed asymmetric ring opening reaction of azabenzonorbomadienes with amines. Zeng, C.; Yang, F.; Chen, J.; Wang, J.;* Fan, B.* Org. Biomol. Chem. 201513, 8425-8428 (Highlighted in Synfacts, 2015, 11, 1078). Link

Graphical abstract: Iridium/copper-cocatalyzed asymmetric ring opening reaction of azabenzonorbornadienes with amines

 

3. Recent Progress on Asymmetric Organocatalytic Construction of Chiral Cyclohexenone Skeletons. Yang, X.; Wang, J.;* Li, P.* Org. Biomol. Chem. 201412, 2499-2513 (Front Cover). Link

Graphical abstract: Recent progress on asymmetric organocatalytic construction of chiral cyclohexenone skeletons

 

2. Organocatalytic Asymmetric Azai-Michael addition of Pyrazole to chalcone. Li, P.*;  Fang, F.; Chen, J.;  Wang, J.* Tetrahedron: Asymmetry. 201425, 98-101. Link

 


 

1. Palladium/Copper Complexes Co-Catalyzed Highly Enantioselective Ring Opening Reaction of Azabenzonorbernadienes with Terminal Alkynes. Fan, B.;* Li, S.; Chen, H.; Lu, Z.; Liu, S.; Yang, Q.; Yu, L.; Zhou, Y.; Wang, J.* Adv. Synth. Catal. 2013, 355, 2827-2832 ( Highlighted in Synfacts, 2014, 10, 59). Link

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