2024年

41.Yang, C., Ji, X., Vaskuri, G.S.S.J. et al. CO prodrugs: a new scaffold of adamantane-fused norbornen-7-ones with tunable water solubility. Med Chem Res (2024). https://doi.org/10.1007/s00044-024-03312-1

40.Sun, J., Wang, X., Gao, Y. et al. H2S scavenger as a broad-spectrum strategy to deplete bacteria-derived H2S for antibacterial sensitization. Nat Commun 15, 9422 (2024).https://doi.org/10.1038/s41467-024-53764-7

2023年

39.J. Med. Chem. 2023, 66, 24, 16546–16567

38.J. Am. Chem. Soc. 2023, 145, 45, 24698–24706

2020年

37.Shengchao Zhou, Yujie Mou, Miao Liu, Qian Du, Basharat Ali, Jurupula Ramprasad, Chunhua Qiao, Li-Fang Hu, and Xingyue JiThe Journal of Organic Chemistry 2020 85 (13), 8352-8359.DOI: 10.1021/acs.joc.0c00559

36. Xingyue Ji, Zhuorong Li. Medicinal chemistry strategies toward host targeting antiviral agents. Med Res Rev. 2020;1–39. DOI: 10.1002/med.21664

2019年

35. Xingyue Ji, Robert E. Aghoghovbia, Ladie Kimberly C. De La Cruz, Zhixiang Pan, Xiaoxiao Yang, Bingchen Yu, and Binghe Wang. Click and Release: A High-Content Bioorthogonal Prodrug with Multiple Outputs. Org Lett. 2019. 21(10):3649-3652. DOI: 10.1021/acs.orglett.9b01086

34. Yixuan Wang, Huiqiang Wang, Xinbei Jiang, Zhi Jiang, Tingting Guo, Xingyue Ji, Yanping Li, Yuhuan Li, and Zhuorong Li. Synthesis and Broad Antiviral Activity of Novel 2-aryl-isoindolin-1-ones towards Diverse Enterovirus A71 Clinical Isolates. Molecules. 2019,24, 985. DOI: 10.3390/molecules24050985

33. Ji Xing-yue, Pan Zhixiang, Li Chunjie, Kang Ting. Cruz Ladie, Yang Lingyun, Ke Bowen, Wang Binghe. Esterase-Sensitive and pH-Controlled Carbon Monoxide Prodrugs for Treating Systemic Inflammation. J Med Chem. 2019 62(6):3163-3168.  DOI: 10.1021/acs.jmedchem.9b00073

32. Ji Xing-yue, Pan Zhixiang, Yu Bingchen, Cruz Ladie, Zheng Yueqin, Ke Bowen, Wang Binghe. Click and release: Bioorthogonal approaches to "on-demand" activation of prodrugs. Chem. Soc. Rev., 2019,48, 1077-1094.  DOI:10.1039/C8CS00395E. 

2018年

31. Yueqing Zheng#, Xingyue Ji#, Bingchen Yu, Kaili Ji, Gallo, D.; Csizmadia, E.; Mengyuan Zhu, Roy Choudhury, M.; De La Cruz, L.; Chittavong, V.; Zhixiang Pan, Zhengnan Yuan, Otterbein, L. E.; Binghe Wang*. Enrichment-triggered Prodrug Activation Demonstrated through Mitochondria-targeted Delivery of Doxorubicin and Carbon Monoxide. Nat. Chem. 2018, 10, 787-794. DOI:10.1038/s41557-018-0055-2. 

30. Xingyue Ji and Binghe Wang. Strategies toward Organic Carbon Monoxide Prodrugs. Acc. Chem. Res. 2018, 51 (6), 1377–1385. DOI:10.1021/acs.accounts.8b00019. 

29. Matheus Correa-Costa, David Gallo, Eva Csizmadia, Edward Gomperts, Judith-Lisa Lieberum, Carl J. Hauser, Xingyue Ji, Binghe Wang, Niels Olsen Saraiva Câmara, Simon C. Robson, and Leo E. Otterbein. Carbon monoxide protects the kidney through the central circadian clock and CD39. Proc Natl Acad Sci U S A. 2018. 115(10):E2302-E2310.  DOI:10.1073/pnas.1716747115. 

28. Zhixiang Pan, Jun Zhang, Kaili Ji, Vayou Chittavong, Xingyue Ji*, and Binghe Wang*.Organic CO Prodrugs Activated by Endogenous ROS. Org. Lett. 2018, 20, 8-11. DOI:10.1021/acs.orglett.7b02775. 

27. Ladie Kimberly C. De La Cruz, Stéphane L. Benoit, Zhixiang Pan, Bingchen Yu, Robert J. Maier, Xingyue Ji*and Binghe Wang*. Click, release, and fluoresce: a chemical strategy for a cascade prodrug system for co-delivery of carbon monoxide, a drug payload and a fluorescent reporter. Org. Lett. 2018, 20 (4), pp 897–900. DOI:10.1021/acs.orglett.7b03348. 

26. Minhang Xin, XinyueJi, Ladie Kimberly De La Cruz, Suresh Thareja, Binghe Wang. Strategies to target the Hedgehog signaling pathway for cancer therapy. Med Res Rev. 2018;38:870–913.  DOI:10.1002/med.21482. 

2017年

25. Zhixiang Pan, Vayou Chittavong, Wei Li, Jun Zhang, Kaili Ji, Mengyuan Zhu, Xingyue Ji,* and Binghe Wang*. Organic CO-prodrugs: Structure CO-release rate relationship Studies. Chem. Eur. J. 2017, 23, 9838-9845. DOI:10.1002/chem.201700936 

24. Xingyue Ji, Ladie Kimberly C. De La Cruz, Zhixiang Pan, Vayou Chittavong and Binghe Wang*. pH-Sensitive metal-free carbon monoxide prodrugs with tunable and predictable release rates. Chem. Commun. 2017, 53, 9628-9631. DOI:10.1039/C7CC04866A. 

23. Xingyue Ji, and Binghe Wang. Toward carbon monoxide based therapeutics: carbon monoxide in a pill. Pharm Pat Anal. 2017, 6, 171-177. DOI:10.4155/ppa-2017-0013. 

22. Xingyue Ji, Kaili Ji, Vayou Chittavong, Bingchen Yu, Zhixiang Pan and Binghe Wang.An esterase-activated click and release approach to metal-free CO-prodrugs. Chem. Commun., 2017, 53, 8296-8299. DOI:10.1039/C7CC03832A. 

21. Suresh Thareja, Mengyuan Zhu, Xingyue Ji* and Binghe Wang*. Boron-based small molecules in disease detection and treatment (2013–2016). Heterocycl. Comm. 2017, 23, 137-153. DOI: 10.1515/hc-2017-0086.

20. Xingyue Ji, Eman M. El-labbad, Kaili Ji, Deena S. Lasheen, Rabah A.T. Serya, Khaled A. Abouzid, and Binghe Wang. Click and Release: SO2 Prodrugs with Tunable Release Rates. Org. Lett. 2017, 19 (4): 818–821. DOI:10.1021/acs.orglett.6b03805. 

19. Wenyi Wang, Xingyue Ji,* Zhenming Du and Binghe Wang*. Sulfur dioxide prodrugs: triggered release of SO2 via a click reaction. Chem. Commun., 2017, 53(8): 1370-1373. DOI:10.1039/c6cc08844a. 

18. Xingyue Ji, Kaili Ji, Vayou Chittavong, Robert E. Aghoghovbia, Mengyuan Zhu, and Binghe Wang.Click and Fluoresce: A Bioorthogonally Activated Smart Probe for Wash-Free Fluorescent Labeling of Biomolecules. J. Org. Chem., 2017, 82(3): 1471–1476. DOI:10.1021/acs.joc.6b02654. 

2016年

17. Wang, K.; Wang, D.; Ji, Xing-yue; Zheng, Yueqin; Wang, Binghe. Fluorescent Probes for Gaseous Biological Signaling Agents.comprehensive supramolecular chemistry ii, 2017:423-434. DOI:10.1016/B978-0-12-409547-2.12628-9. 

16. Xingyue Ji, Cheng Zhou, Kaili Ji, Robert E. Aghoghovbia, Zhixiang Pan, Vayou Chittavong, Bowen Ke, Binghe Wang. Click and Release: A Chemical Strategy toward Developing Gasotransmitter Prodrugs by Using an Intramolecular Diels–Alder Reaction. Angew. Chem. Int. Ed. 2016, 55(51):15846-15851. DOI:10.1002/ange.201608732. 

15. Xingyue Ji, Cheng Zhou, Kaili Ji, Robert E. Aghoghovbia, Zhixiang Pan, Vayou Chittavong, Bowen Ke, Binghe Wang. Click and Release: A Chemical Strategy toward Developing Gasotransmitter Prodrugs by Using an Intramolecular Diels–Alder Reaction. Angew. Chem. Int. Ed. 2016, 55(51):15846-15851. DOI:10.1002/anie.201608732. 

14. Xingyue Ji, Jinhua Chen, Guanghui Zheng, Menghao Huang, Lei Zhang, Hong Yi, Jie Jin, Jiandong Jiang, Zonggen Peng, and Zhuorong Li. Design and Synthesis of Cajanine Analogues against Hepatitis C Virus through Down-Regulating Host Chondroitin Sulfate N-Acetylgalactosaminyltransferase 1. J. Med. Chem., 2016, 59 (22), 10268–10284. DOI:10.1021/acs.jmedchem.6b01301. 

13.Xingyue Ji, Krishna Damera, Yue-qin Zheng, Bing-chen Yu, Leo E. Otterbein, Bing-he Wang. Toward Carbon Monoxide–Based Therapeutics: Critical Drug Delivery and Developability Issues. J. Pharm. Sci. 2016, 105(2):406-16. DOI:10.1016/j.xphs.2015.10.018. 

2015年

12. Zhang, Lin; Shan, Yuanyuan; Ji, Xing-yue; Zhu, Mengyuan; Li, Chuansheng; Sun, Ying; Si, Ru; Pan, Xiaoyan; Wang, Jinfeng; Ma, Weina; Dai, Bingling; Wang, Binghe; Zhang, Jie. Discovery and evaluation of triple inhibitors of VEGFR-2, TIE-2 and EphB4 as anti-angiogenic and anti-cancer agents.Oncotarget, 2017, 8, pp: 104745-104760. DOI:10.18632/oncotarget.20065. 

11. Yueqin Zheng, Xingyue Ji, Kaili Ji, Binghe Wang. Hydrogen sulfide prodrugs—a review. Acta Pharmaceutica Sinica B 2015; 5(5): 367–377.  DOI:10.1016/j.apsb.2015.06.004. 

2014年

10.Xing-yue Ji, Si-tu Xue, Yue-chen Zhan, Jia-jia Shen, Lin-tao Wu, Jie Jin, Zhen Wang, Zhuo-rong Li. Design, synthesis and antiproliferative activity of a novel class of indole-2-carboxylate derivatives. Eur. J. Med. Chem. 2014, 83: 409–418. DOI:10.1016/j.ejmech.2014.05.043. 

9. Guang-hui Zheng, Jia-jia Shen, Hong Yi, Si-tu Xue, Zhen Wang, Xing-yue Ji*, and Zhuo-rong Li*. Design, synthesis and in vitro and in vivo antitumor activity of 3-benzylideneindolin-2-one derivatives, a novel class of small-molecule inhibitors of the MDM2-p53 interaction. Eur. J. Med. Chem. 2014, 81: 277-88. DOI:10.1016/j.ejmech.2014.05.027. 

2013年

8. Xue, Si-Tu; He, Wei-Ying; Ma, Lin-Lin; Wang, Hui-Qiang; Wang, Bo; Zheng, Guang-Hui; Ji, Xing-yue; Zhang, Tian; Li, Yu-Huan; Jiang, Jian-Dong; Li, Zhuo-Rong. Synthesis and Anti-Influenza Virus Activities of a Novel Class of Gastrodin Derivatives. Molecules (Basel, Switzerland). 2013. 18. 3789-805. DOI:10.3390/molecules18043789. 

7. Ji, Xing-yue; Jin, Jie; Zheng, Guang-hui; Li, Zhuo-rong. (E)-2-Hy-droxy-4-meth-oxy-3-(3-methyl-but-2-en-yl)-6-styryl-benzoic acid. Acta Crystallogr Sect E Struct Rep Online. 2013. 69(Pt 1):o91.  DOI:10.1107/S1600536812050258. 

6. Xing-Yue Ji, Hui-Qiang Wang, Lan-Hu Hao, Wei-Ying He, Rong-Mei Gao, Yan-Ping Li, Yu-Huan Li, Jian-Dong Jiang and Zhuo-Rong Li. Synthesis and Antiviral Activity of N-Phenylbenzamide Derivatives, a Novel Class of Enterovirus 71 Inhibitors. Molecules. 2013, 18(3): 3630-3640. DOI:10.3390/molecules18033630. 

2012年

5. Zhang Dajun^#, Ji Xing-yue^#, Gao Rongmei, Wang Huiqiang, Meng Shuai, Zhong Zhaojin, Li Yuhuan, Jiang Jiandong, Li Zhuorong. Synthesis and antiviral activities of a novel class of thioflavone and flavonoid analogues. Acta Pharmaceutica Sinica B. 2012. 2. 575–580. DOI:10.1016/j.apsb.2012.10.005. 

4. Ji X Y , Li Z R . Synthesis and antimycobacterial activity of ternatolide. Journal of Chinese Pharmaceutical Sciences, 2012, 21(3):265-268. DOI:10.5246/jcps.2012.03.034. 

2011年

3. Xingyue Ji, Si-tu Xue, Zong-ying Liu, Guang-hui Zheng, and Zhuo-rong Li*. Total synthesis of cajanine and its antiproliferative activity against human hepatoma cells. Acta. Pharm. Sin.B. 2011, 1(2): 93-99. DOI:10.1016/j.apsb.2011.06.005. 

2. Yang Yanhui, Gao Peng, Liu Yishuang, Ji Xing-yue, Gan Maoluo, Guan Yan, Hao Xueqin, Li Zhuorong, Xiao Chunling. A discovery of novel Mycobacterium tuberculosis pantothenate synthetase inhibitors based on the molecular mechanism of actinomycin D inhibition. Bioorganic & medicinal chemistry letters. 2011.21. 3943-6. DOI:10.1016/j.bmcl.2011.05.021. 

2010年

1. Ji Xing-yue, Zhong Zhao-jin, Xue Si-tu, Meng Shuai, He Wei-ying, Gao Rong-mei, Li Yu-huan, Li Zhuo-Rong. Synthesis and Antiviral Activities of Synthetic Glutarimide Derivatives. Chemical & pharmaceutical bulletin. 2010. 58. 1436-41. DOI:10.1248/cpb.58.1436.