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成果及论文

62.Yingyin Zhang, Qingyuan Feng, Yu Zheng, Yanju Lu, Saihu Liao, and Shenlin Huang* Radical Hydro-Fluorosulfonylation of Propargylic Alcohols via Electron Donor–Acceptor Photoactivation. Org. Lett. 2024, 26, 1410–1415.https://doi.org/10.1021/acs.orglett.4c00010

Figure 1

61.Tianyu He, Chaoqiang Liang, Haoyuan Cheng, Shuai Shi, and Shenlin Huang* Cathodically Coupled Electrolysis to Access Biheteroaryls. Org. Lett. 2024, 26, 607–612.https://doi.org/10.1021/acs.orglett.3c03859

Figure 1

60.Peng-Cheng Xu, Shencheng Qian, Xiangtai Meng, Yu Zheng, and Shenlin Huang* Electrochemical Ring-Opening of Cyclopropylamides with Alcohols toward the Synthesis of 1,3-Oxazines.Org. Lett. 2023,https://doi.org/10.1021/acs.orglett.3c03537

Figure 1

59.Qingyuan Feng, Tianyu He, Shencheng Qian, Peng Xu, Saihu Liao, and Shenlin Huang* Electroreductive Hydroxy Fluorosulfonylation of Alkenes. Nat. Commun. 2023https://www.nature.com/articles/s41467-023-44029-w.

58.Yu Zheng, *Wenguang Lu, Tianting Ma, Shenlin Huang*Recent advances in photochemical and electrochemical strategies for the synthesis of sulfonyl fluorides.Org. Chem. Front., 2024,https://doi.org/10.1039/D3QO01610B

Graphical abstract: Recent advances in photochemical and electrochemical strategies for the synthesis of sulfonyl fluorides

57.Meizhong Tang, Ye Wang, Shenlin Huang*, Lan-Gui Xie Synthesis of Aryl Thioalkynes Enabled by Electrophilic Sulfenylation of Alkynes and the Following Elimination.J. Org. Chem. 2023, 88, 21, 15466–15472https://doi.org/10.1021/acs.joc.3c01592

56. Xueyan Zhao, Dengfeng Chen, Shengzhen Zhu, Jinyue Luo, Saihu Liao, Binnan Zheng, Shenlin Huang* Fluorosulfonylvinylation of Unactivated C(sp3)–H via Electron Donor–Acceptor Photoactivation. Org. Lett. 2023, 25, 3109.https://doi.org/10.1021/acs.orglett.3c00950

55. Shuai Shi, Xueyan Zhao, Dengfeng Chen, Jinyue Luo, Saihu Liao, Shenlin Huang* C(sp3)–H fluorosulfonylvinylation/aza-Michael addition approach to FSO2-functionalized tetrahydropyridines. Org. Chem. Front. 2023, 10, 3805.https://doi.org/10.1039/D3QO00639E

Graphical abstract: C(sp3)–H fluorosulfonylvinylation/aza-Michael addition approach to FSO2-functionalized tetrahydropyridines

54. Yu Zheng,* Tianting Ma, Bingcong Liu, Shenlin Huang* SO2ClF-promoted chlorination-oxidation of 2-methylindoles: a one-step synthetic method to access 2,3-difunctionalized indoles. Org. Chem. Front., 2023,10, 4100-4104.https://doi.org/10.1039/D3QO00879G

Graphical abstract: SO2ClF-promoted chlorination-oxidation of 2-methylindoles: a one-step synthetic method to access 2,3-difunctionalized indoles

53. Meizhong Tang, Ye-Xin Wang, Shenlin Huang,* Lan-Gui Xie Regio- and stereoselective oxidative conversion of alkynes to sulfenylated α,β-unsaturated carbonyls. Org. Chem. Front. 2023, 10, 2416.https://doi.org/10.1039/D3QO00236E

52. Tianting Ma, Yu Zheng,* Shenlin Huang* SO2ClF: A Reagent for Controllable Chlorination and Chlorooxidation of Simple Unprotected Indoles. J. Org. Chem. 2023, 88, 4839.https://doi.org/10.1021/acs.joc.3c00039

Figure 1

51. Tianyu He, Chaoqiang Liang, Shenlin Huang* Cobalt-electrocatalytic C–H hydroxyalkylation of N-heteroarenes with trifluoromethyl ketones. Chem. Sci. 2023, 14, 143.https://doi.org/ 10.1039/D2SC05198B

image file: d2sc05198b-s1.tif

50. Qingyuan Feng, Yamin Wang, Binnan Zheng, Shenlin Huang* Electrochemical Oxidative Cleavage of Alkynes to Carboxylic Acids. Org. Lett. 2023, 25, 293.https://doi.org/10.1021/acs.orglett.2c04204

Figure 1

49. Jiajin Xia, Baolong Zhu, Qiuling Wan, Yinghua Yu,* Shenlin Huang,* Jian Zhang, Xueliang Huang* Gold-Catalyzed Cascade Reaction of Diynamides with Allylic Alcohols: A Versatile Platform to Allenamide, 2-Aminofuran and Bridged [2.2.2]Octadiene Derivatives. Chem. Eur. J. 2023, 29, e202300826.https://doi.org/10.1002/chem.202300826

Description unavailable

48. Shencheng Qian, Pengcheng Xu, Yu Zheng, Shenlin Huang* Electrochemical oxythiocyanation of ortho-olefinic amides: Access to diverse thiocyanated benzoxazines. Tetrahedron Let. 2023, 116, 154341.https://doi.org/10.1016/j.tetlet.2023.154341

47. Ping Jiang, Rui Liu, Xiangtai Meng, Binnan Zheng, Yu Zheng, Shenlin Huang* Electrochemical Synthesis of 3-Sulfonylindoles via Annulation of o-Alkynylanilines with Sodium Sulfinates. Synthesis 2023, 10.1055/a-1996-8054 (Invited)https://doi.org/10.1055/a-1996-8054

46. Yu Zheng, Shencheng Qian, Pengcheng Xu, Binnan Zheng, Shenlin Huang* Electrochemical Oxidative Thiocyanosulfonylation of Aryl Acetylenes. Chin. J. Org. Chem. 2022, 42, 4275. (Invited)https://doi.org/10.6023/cjoc202209041

45. Yu Zheng, Shencheng Qian, Pengcheng Xu, Tianting Ma, Shenlin Huang* BF3·Et2O Promoted Inverse-Electron-Demand Oxa-Diels-Alder Reaction of Alkylidene Isoxazol-5-ones with Unactivated Alkenes. Adv. Synth. Catal. 2022, 364, 3800.https://doi.org/10.1002/adsc.202200805

image

44. Meizhong Tang, Yongjiao Wei, Shenlin Huang,* Lan-Gui Xie* Regio- and Stereoselective Synthesis of β‑Methylthio Vinyl Triflates. Org. Lett. 2022, 24, 7026.https://doi.org/10.1021/acs.orglett.2c02880

43. Yuanyuan Fu, Shengzhen Zhu, Xueyan Zhao, Shenlin Huang* Photoredox-catalyzed coupling of acyl oxime acetates with thiophenols to give arylthioesters in water at room temperature. Green Chem. 2022, 24, 6849.https://doi.org/10.1039/D2GC02438A

Graphical abstract: Photoredox-catalyzed coupling of acyl oxime acetates with thiophenols to give arylthioesters in water at room temperature

42. Sichang Wang, Ming Yuan, Qunzheng Zhang, Shenlin Huang* Recent progress in copper nanocatalysis for sustainable transformations. Curr. Opin. Green. Sustain. Chem. 2022, 38, 100698.https://doi.org/10.1016/j.cogsc.2022.100698

Scheme 1

41. Qingyuan Feng, Yuanyuan Fu, Yu Zheng, Saihu Liao, Shenlin Huang* Electrochemical Synthesis of β‑Keto Sulfonyl Fluorides via Radical Fluorosulfonylation of Vinyl Triflates. Org. Lett. 2022, 24, 3702.https://doi.org/10.1021/acs.orglett.2c01336

40. Xiangtai Meng, Hehua Xu, Rui Liu, Yu Zheng, Shenlin Huang* Electrochemical triamination of alkynes: controllable synthesis of functionalized indolines and indoles. Green Chem. 2022, 24, 4754.https://doi.org/10.1039/D2GC01129H

Graphical abstract: Electrochemical triamination of alkynes: controllable synthesis of functionalized indolines and indoles

39. Jinli Wang, Meizhong Tang, Weijin Gu, Shenlin Huang, and Lan-Gui Xie* Synthesis of Pyrrole via Formal Cycloaddition of Allyl Ketone and Amine under Metal-Free Conditions. J. Org. Chem. 2022, 87, 12482.https://doi.org/10.1021/acs.joc.2c01565

Figure 1

38. Xiangtai Meng, Hehua Xu, Yu Zheng, Jinyue Luo, Shenlin Huang* Electrochemical Decarboxylative Oxygenation of Carboxylic Acids. ACS Sustainable Chem. Eng. 2022, 10, 5067. (Invited)https://doi.org/10.1021/acssuschemeng.2c01495

Figure 1

37. Yuan Huang, Xueyan Zhao, Dengfeng Chen, Yu Zheng, Jinyue Luo, Shenlin Huang* Access to Sulfocoumarins by Three-Component Reaction of β-Keto Sulfonyl Fluorides, Arynes, and DMF. Eur. J. Org. Chem. 2022, e202200715.https://doi.org/10.1002/ejoc.202200715

Description unavailable

36. Ping Jiang, Yaming Wang, Dengfeng Chen, Yu Zheng,* Shenlin Huang* Synthesis of 3-Acyl-Isoxazoles via Radical 5-endo trig Cyclization of β,γ-Unsaturated Ketones with NaNO2. Eur. J. Org. Chem. 2022, e202101411.https://doi.org/10.1002/ejoc.202101411

Description unavailable

35. Yingyin Zhang, Baolong Zhu, Yu Zheng, Shenlin Huang A rosin-based surfactant enabling cross-couplings of vinyl dibromides with sulfonamides in water. J. Organomet. Chem. 2022, 122321. (Invited)https://doi.org/10.1016/j.jorganchem.2022.122321

34. Yuan Huang, Dengfeng Chen, Yu Zheng,* Shenlin Huang* Synthesis of 3-Sulfonyl Indenones via Copper-Catalyzed Redox-Neutral Coupling Reaction. ChemistrySelect 2022, 7, e20210434.https://doi.org/10.1002/slct.202104347

Description unavailable

33. Dengfeng Chen, Tianyu He, Yongcan Jin,* Shenlin Huang* Electrooxidative Dearomatization to Spiroisoxazolines: Application to Total Synthesis of Xanthoisoxazoline B. Adv. Syn. Catal. 2022364, 286.https://doi.org/10.1002/adsc.202101062

image

32. Hehua Xu, Xiangtai Meng, Yu Zheng, Jinyue Luo,* Shenlin Huang* Electrochemical Annulations of o-Alkynylanilines for Synthesis of 3-Iodoindoles. Chin. J. Org. Chem. 2021, 41, 4696. (Invited)

31. Dengfeng Chen, Xingliang Nie, Qingyuan Feng, Yingyin Zhang, Yiheng Wang, Qiuyue Wang, Lin Huang, Shenlin Huang,* Saihu Liao* Electrochemical Oxo-Fluorosulfonylation of Alkynes under Air: Facile Access to β-Keto Sulfonyl Fluorides. Angew. Chem. Int. Ed. 2021, 60, 27271.

30. Yuanyuan Fu, Xueyan Zhao, Dengfeng Chen, Jinyue Luo, Shenlin Huang* Cu-catalyzed coupling of indanone oxime acetates with thiols to 2,3-difunctionalized indenones. Chem. Commun. 2021, 57, 10719.

29. Tianyu He, Dengfeng Chen, Shencheng Qian, Yu Zheng, Shenlin Huang* Selective C–C Bond Cleavage of Cycloalkanones by NaNO2/HCl. Org. Lett. 2021, 23, 6525.

28. Xiangtai Meng, Dengfeng Chen, Rui Liu, Ping Jiang, Shenlin Huang* Synthesis of 2-(Cyanomethyl)benzoic Esters via Carbon–Carbon Bond Cleavage of Indanones. J. Org. Chem. 2021, 86, 10852.

27. Xu-Min Cai, Yuting Lin, Ying Li, Zaiyu Wang, Xueqian Zhao, Shenlin Huang,* Zheng Zhao,* Ben Zhong Tang* BioAIEgens Derived from Rosin: How Does Molecular Motion Affect Their Photophysical Processes in Solid State? Nat. Commun. 2021, 12, 1773.

26. Meizhong Tang, Shuxiong Han, Shenglan Huang, Shenlin Huang, Lan-Gui Xie* Carbosulfenylation of Alkenes with Organozinc Reagents and Dimethyl(methylthio)sulfonium Trifluoromethanesulfonate. Org. Lett. 2020, 22, 9729.

25. Xiangtai Meng, Hehua Xu, Xiaoji Cao, Xu-Min Cai, Jinyue Luo, Fei Wang, Shenlin Huang* Electrochemically Enabled Sulfonylation of Alkynes with Sodium Sulfinates. Org. Lett. 2020, 22, 6827. 

24. Dengfeng Chen, Yaming Wang, Xu-Min Cai, Xiaoji Cao, Ping Jiang, Fei Wang, Shenlin Huang* Synthesis of Spiroisoxazolines via TEMPO/NaNO2-Catalyzed Aerobic Oxidative Dearomatization. Org. Lett. 2020, 22, 6847. 

23. Chenjing Liu, Dengfeng Chen, Yuanyuan Fu, Fei Wang, Jinyue Luo*, Shenlin Huang* Sulfoxide Reduction/C(sp3)–S Metathesis Cascade in Ionic Liquid. Org. Lett. 2020, 22, 5701.

22. Dengfeng Chen, Tianyu He, Yuan Huang, Jinyue Luo, Fei Wang, Shenlin Huang* Synthesis of Spiroisoxazolines via an Oximation/Dearomatization Cascade under Air. Org. Lett. 2020, 22, 4429.

21. Baolong Zhu, Lei Zhu, Jiajin Xia, Shenlin Huang,* Xueliang Huang* Gold-catalyzed cycloisomerization of enynamides: Regio- and stereoselective approach to tetracyclic spiroindolines. Tetrahedron 2020, 76, 131056.

20. Shengzhen Zhu, Yu Zhang, Jinyue Luo, Fei Wang, Xiaoji Cao, Shenlin Huang* Temperature-controlled regioselective thiolation of 2-indolylmethanols under aqueous micellar conditions. Green Chem. 2020, 22, 657.

19. Xiangtai Meng, Yu Zhang, Jinyue Luo, Fei Wang, Xiaoji Cao, Shenlin Huang* Electrochemical Oxidative Oxydihalogenation of Alkynes for the Synthesis of α,α-Dihaloketones. Org. Lett. 2020, 22, 1169.

18. Tianxiao Xu, Tianpeng Cao, Qingyuan Feng, Shenlin Huang,* Saihu Liao* Metal-free dehydrosulfurization of thioamides to nitriles under visible light. Chem. Commun. 2020, 56, 5151.

17. Xiangtai Meng, Dengfeng Chen, Xiaoji Cao, Jinyue Luo, Fei Wang, Shenlin Huang* Synthesis of polysubstituted cyclic 1,2-diketonesenabled by iterative sulfoxide-mediated arylation. Chem. Commun. 2019, 55, 12495.

16. Wenqian Lina, Dengfeng Chen, Qiang Yong, Caoxing Huang,* Shenlin Huang* Improving enzymatic hydrolysis of acid-pretreated bamboo residues using amphiphilic surfactant derived from dehydroabietic acid. Bioresour. Technol. 2019, 293, 122055.

15. Dengfeng Chen, Yuanyuan Fu, Xiaoji Cao, Jinyue Luo, Fei Wang, Shenlin Huang* Metal-Free Cyclopropanol Ring Opening C(sp3)–C(sp2) Cross-Couplings with Aryl Sulfoxides. Org. Lett. 2019, 21, 5600.

14. Heng Zhang, Yinghua Yu, Shenlin Huang, Xueliang Huang* Palladium-Catalyzed Cascade Reaction of o-Bromobenzaldehydes with N-Sulfonylhydrazones: An Efficient Approach to the Naphthalene Skeleton. Adv. Syn. Catal. 2019, 361, 1576.

13. Yunqin Yang, Xiangtai Meng, Baolong Zhu, Ying Jia, Xiaoji Cao, Shenlin Huang* A Micellar Catalysis Strategy for Amidation of Alkynyl Bromides: Synthesis of Ynamides in Water. Eur. J. Org. Chem. 2019, 1166.

12. Dengfeng Chen, Yuchen Zhang, Xingyu Pan, Fei Wang, Shenlin Huang* Oxidation of Tertiary Aromatic Alcohols to Ketones in Water. Adv. Syn. Catal. 2018, 360, 3607.

11. Qingyuan Feng, Dengfeng Chen, Mei Hong, Fei Wang, Shenlin Huang* Phenyliodine(III) Bis(trifluoroacetate) (PIFA)-Mediated Synthesis of Aryl Sulfides in Water. J. Org. Chem. 2018, 83, 7553.

10. Xiao Chen, Xinfei Chen, Xu-Min Cai*, Shenlin Huang, Fei Wang* Cellulose Dissolution in a Mixed Solvent of Tetra(n‑butyl)ammonium Hydroxide/Dimethyl Sulfoxide via Radical Reactions. ACS Sustainable Chem. Eng. 2018, 6, 2898. 

9. Tao Yuan, Shenlin Huang, Chun Cai, Guo-ping Lu* Metal-free electrophilic phosphination of electron-rich arenes, arenols and aromatic thiols with diarylphosphine oxides. Org. Biomol. Chem. 2018, 16, 30.

8. Dengfeng Chen, Qingyuan Feng, Yunqin Yang, Xu-Min Cai, Fei Wang, Shenlin Huang* Metal-Free O–H/C–H Difunctionalization of Phenols by o-Hydroxyarylsulfonium Salts in Water. Chem. Sci. 2017, 8, 1601. 

7. Takashi Nishikata, Alexander R. Abela, Shenlin Huang, Bruce H. Lipshutz* Cationic Pd(II)-catalyzed C–H Activation/Cross-coupling Reactions at Room Temperature: Synthetic and Mechanistic Studies. Beilstein J. Org. Chem. 2016, 12, 1040.

6. Shenlin Huang, Lisa Kötzner, Chandra Kanta De, Benjamin List* Catalytic Asymmetric Dearomatizing Redox Cross Coupling of Ketones with Aryl Hydrazines Giving 1,4-Diketones. J. Am. Chem. Soc. 2015, 137, 3446. 

5. Bruce H. Lipshutz*, Shenlin Huang, Wendy Wen Yi Leong, Guofu Zhong, Nicholas A. Isley C–C Bond Formation via Copper-Catalyzed Conjugate Addition Reactions to Enones in Water at Room Temperature. J. Am. Chem. Soc. 2012, 134, 19985.

4. Shenlin Huang, Tue B. Petersen, Bruce H. Lipshutz* Total Synthesis of (+)-Korupensamine B via an Atropselective Intermolecular Biaryl Coupling. J. Am. Chem. Soc. 2010, 132, 14021.

3. Shenlin Huang, Karl R. Voigtritter, John B. Unger, Bruce H. Lipshutz* Asymmetric CuH-Catalyzed 1,4-Reductions in Water at Room Temperature. Synlett 2010, 2041.

2. Takashi Nishikata, Alexander R. Abela, Shenlin Huang, Bruce H. Lipshutz* Cationic Palladium(II) Catalysis: C-H Activation/Suzuki-Miyaura Couplings at Room Temperature. J. Am. Chem. Soc. 2010, 132, 4978.

1. Ching-Tien Lee, Shenlin Huang, Bruce H. Lipshutz* Cu/C-Catalyzed, Tandem One-Pot Diazo Transfer-Click Reactions Adv. Syn. Catal. 2009, 353, 3139.